{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T03:02:00Z","timestamp":1793070120906,"version":"4.5.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.ejogrb.2025.114668","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T15:53:23Z","timestamp":1755878003000},"page":"114668","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Ovarian response in natural cycle, minimal stimulation and conventional IVF protocols in relation to anti-mullerian hormone level \u2013 A multi-center study"],"prefix":"10.1016","volume":"314","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6998-0914","authenticated-orcid":false,"given":"I.","family":"Magaton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Arni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"von Arnim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Nordin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Siercks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RM.","family":"Popovici","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Bohlen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Eisenhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Reeka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J-S.","family":"Lanowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"L\u00fchr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Roumet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"von Wolff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2025.114668_b0005","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/humupd\/dmn053","article-title":"The clinical significance of the retrieval of a low number of oocytes following mild ovarian stimulation for IVF: a meta-analysis","volume":"15","author":"Verberg","year":"2009","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2025.114668_b0010","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.fertnstert.2015.05.006","article-title":"Mild ovarian stimulation with clomiphene citrate launch is a realistic option for in vitro fertilization","volume":"104","author":"Ferraretti","year":"2015","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2025.114668_b0015","series-title":"Natural Cycle and Minimal Stimulation IVF","author":"Von Wolff","year":"2022"},{"key":"10.1016\/j.ejogrb.2025.114668_b0020","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.3390\/cells11101636","article-title":"Ultrastructural Evaluation of the Human Oocyte at the Germinal Vesicle Stage during the Application of Assisted Reproductive Technologies","volume":"11","author":"Palmerini","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.ejogrb.2025.114668_b0025","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/ijgo.13626","article-title":"Comparison of in vitro fertilization cycles stimulated with 20 mg letrozole daily versus high-dose gonadotropins in Rotterdam Consensus ultra-poor responders: a proof of concept","volume":"156","author":"Khojah","year":"2022","journal-title":"Int J Gynecol Obstet"},{"key":"10.1016\/j.ejogrb.2025.114668_b0030","doi-asserted-by":"crossref","first-page":"2678","DOI":"10.1093\/humrep\/deq247","article-title":"Mild ovarian stimulation for IVF: 10 years later","volume":"25","author":"Fauser","year":"2010","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2025.114668_b0035","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.rbmo.2020.05.010","article-title":"Mild ovarian stimulation for IVF is the smartest way forward","volume":"41","author":"Nargund","year":"2020","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.ejogrb.2025.114668_b0040","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1093\/humupd\/dmaa035","article-title":"Mild versus conventional ovarian stimulation for IVF in poor, normal and hyper-responders: a systematic review and meta-analysis","volume":"27","author":"Datta","year":"2021","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2025.114668_b0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.rbmo.2024.104696","article-title":"Oocyte retrieval of few follicles does not require analgesia \u2013 a large-scale multicentre pain analysis","volume":"50","author":"Magaton","year":"2025","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.ejogrb.2025.114668_b0050","article-title":"Fresh and cumulative live birth rates in mild versus conventional stimulation for IVF cycles in poor ovarian responders: a systematic review and meta-analysis","volume":"hoaa066","author":"Montoya-Botero","year":"2021","journal-title":"Hum Reprod Open 2021"},{"key":"10.1016\/j.ejogrb.2025.114668_b0055","first-page":"35","article-title":"Comparison pregnancy outcomes between minimal stimulation protocol and conventional GnRH antagonist protocols in poor ovarian responders","volume":"10","author":"Pilehvari","year":"2016","journal-title":"J Fam Reprod Heal"},{"key":"10.1016\/j.ejogrb.2025.114668_b0060","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.fertnstert.2005.01.117","article-title":"The aromatase inhibitor letrozole increases the concentration of intraovarian androgens and improves in vitro fertilization outcome in low responder patients: a pilot study","volume":"84","author":"Garcia-Velasco","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2025.114668_b0065","doi-asserted-by":"crossref","first-page":"2496","DOI":"10.1093\/humrep\/dex318","article-title":"Individualized versus standard FSH dosing in women starting IVF\/ICSI: An RCT. Part 1: The predicted poor responder","volume":"32","author":"Van Tilborg","year":"2017","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2025.114668_b0070","doi-asserted-by":"crossref","first-page":"77","DOI":"10.52054\/FVVO.14.1.013","article-title":"Clomiphene citrate stimulated cycles \u2013 additional gonadotrophin stimulation increases endometrium thickness without increasing implantation rate","volume":"14","author":"Magaton","year":"2022","journal-title":"Facts, Views Vis ObGyn"},{"key":"10.1016\/j.ejogrb.2025.114668_b0075","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/aogs.13281","article-title":"Treatment-related psychological stress in different in vitro fertilization therapies with and without gonadotropin stimulation","volume":"97","author":"Haemmerli Keller","year":"2018","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ejogrb.2025.114668_b0080","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.855131","article-title":"Optimal Timing of Ovulation Triggering to Achieve Highest Success Rates in Natural Cycles\u2014An Analysis Based on Follicle Size and Oestradiol Concentration in Natural Cycle IVF","volume":"13","author":"Helmer","year":"2022","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.ejogrb.2025.114668_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.jogoh.2022.102416","article-title":"High dose gonadotropin stimulation increases endometrial thickness but this gonadotropin induced thickening does not have an effect on implantation","volume":"51","author":"Magaton","year":"2022","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"10.1016\/j.ejogrb.2025.114668_b0090","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s43032-022-01016-8","article-title":"Gonadotropin Stimulation Reduces the Implantation and Live Birth Rate but Not the Miscarriage Rate of Embryos Transferred When Compared to Unstimulated In Vitro Fertilization","volume":"30","author":"Mitter","year":"2023","journal-title":"Reprod Sci"},{"key":"10.1016\/j.ejogrb.2025.114668_b0095","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.fertnstert.2007.12.013","article-title":"The role of antimullerian hormone in prediction of outcome after IVF: comparison with the antral follicle count","volume":"91","author":"Broer","year":"2009","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2025.114668_b0100","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1093\/humupd\/dmt037","article-title":"Individualization of controlled ovarian stimulation in IVF using ovarian reserve markers: from theory to practice","volume":"20","author":"La Marca","year":"2014","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2025.114668_b0105","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.rbmo.2017.01.012","article-title":"A randomized controlled trial investigating the use of a predictive nomogram for the selection of the FSH starting dose in IVF\/ICSI cycles","volume":"34","author":"Allegra","year":"2017","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.ejogrb.2025.114668_b0110","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1093\/humrep\/den480","article-title":"Anti-M\u00fcllerian hormone-based approach to controlled ovarian stimulation for assisted conception","volume":"24","author":"Nelson","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2025.114668_b0115","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S0140-6736(07)61602-X","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"370","author":"von Elm","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.ejogrb.2025.114668_b0120","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1016\/j.fertnstert.2013.03.001","article-title":"Why we may abandon basal follicle-stimulating hormone testing: a sea change in determining ovarian reserve using antim\u00fcllerian hormone","volume":"99","author":"Toner","year":"2013","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2025.114668_b0125","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/rmb2.12270","article-title":"Different anti-M\u0171llerian hormone (AMH) levels respond to distinct ovarian stimulation methods in assisted reproductive technology (ART): Clues to better ART outcomes","volume":"18","author":"Ishii","year":"2019","journal-title":"Reprod Med Biol"},{"key":"10.1016\/j.ejogrb.2025.114668_b0130","article-title":"Female BMI has an effect on oocyte gene expression pattern","volume":"9","author":"Liu","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.ejogrb.2025.114668_b0135","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1016\/j.fertnstert.2019.08.009","article-title":"Effect of body mass index on pregnancy outcomes with the freeze-all strategy in women with polycystic ovarian syndrome","volume":"112","author":"Qiu","year":"2019","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2025.114668_b0140","doi-asserted-by":"crossref","first-page":"409","DOI":"10.3109\/09513590.2015.1014785","article-title":"Obesity adversely impacts the number and maturity of oocytes in conventional IVF not in minimal stimulation IVF","volume":"31","author":"Zhang","year":"2015","journal-title":"Gynecol Endocrinol"},{"key":"10.1016\/j.ejogrb.2025.114668_b0145","doi-asserted-by":"crossref","first-page":"880","DOI":"10.3109\/09513590.2011.569600","article-title":"Oocyte morphological abnormalities in overweight women undergoing in vitro fertilization cycles","volume":"27","author":"Depalo","year":"2011","journal-title":"Gynecol Endocrinol"},{"key":"10.1016\/j.ejogrb.2025.114668_b0150","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1093\/humrep\/dead042","article-title":"The combined effect of BMI and age on ART outcomes","volume":"38","author":"Rafael","year":"2023","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2025.114668_b0155","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1016\/j.fertnstert.2016.06.004","article-title":"Feasibility of a brief, intensive weight loss intervention to improve reproductive outcomes in obese, subfertile women: a pilot study","volume":"106","author":"Rothberg","year":"2016","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ejogrb.2025.114668_b0160","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1093\/humrep\/deq306","article-title":"Female obesity adversely affects assisted reproductive technology (ART) pregnancy and live birth rates","volume":"26","author":"Luke","year":"2011","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2025.114668_b0165","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1186\/s12884-020-03446-1","article-title":"Anti-M\u00fcllerian hormone is correlated with cumulative live birth in minimal ovarian stimulation with clomiphene citrate: a retrospective cohort study","volume":"20","author":"Ezoe","year":"2020","journal-title":"BMC Pregnancy Childbirth"},{"key":"10.1016\/j.ejogrb.2025.114668_b0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/581451","article-title":"Comparison of IVF Outcomes between Minimal Stimulation and High-Dose Stimulation for Patients with Poor Ovarian Reserve","volume":"2014","author":"Lazer","year":"2014","journal-title":"Int J Reprod Med"},{"key":"10.1016\/j.ejogrb.2025.114668_b0175","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.tjog.2018.08.018","article-title":"The role of anti-Mullerian hormone in predicting the response to clomiphene citrate in unexplained infertility","volume":"57","author":"Coskun","year":"2018","journal-title":"Taiwan J Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2025.114668_b0180","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.beem.2018.10.005","article-title":"The role of Natural Cycle IVF in assisted reproduction","volume":"33","author":"von Wolff","year":"2019","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1016\/j.ejogrb.2025.114668_b0185","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.rbmo.2022.11.008","article-title":"Oocyte maturity, oocyte fertilization and cleavage-stage embryo morphology are better in natural compared with high-dose gonadotrophin stimulated IVF cycles","volume":"46","author":"Magaton","year":"2023","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.ejogrb.2025.114668_b0190","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1093\/humrep\/dez184","article-title":"Individualized ovarian stimulation in IVF\/ICSI treatment: it is time to stop using high FSH doses in predicted low responders","volume":"35","author":"Leijdekkers","year":"2020","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ejogrb.2025.114668_b0195","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1111\/aogs.13691","article-title":"The greater incidence of small-for-gestational-age newborns after gonadotropin-stimulated in vitro fertilization with a supraphysiological estradiol level on ovulation trigger day","volume":"98","author":"Kohl Schwartz","year":"2019","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ejogrb.2025.114668_b0200","first-page":"23","article-title":"In Vitro Fertilization Technology and Child Health","volume":"117","author":"von Wolff","year":"2020","journal-title":"Dtsch Arztebl Int"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211525009443?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211525009443?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T19:43:37Z","timestamp":1762285417000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211525009443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":40,"alternative-id":["S0301211525009443"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2025.114668","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ovarian response in natural cycle, minimal stimulation and conventional IVF protocols in relation to anti-mullerian hormone level \u2013 A multi-center study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2025.114668","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"114668"}}