{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T15:20:22Z","timestamp":1788880822114,"version":"build-2803163510"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.ejogrb.2025.114887","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T02:59:06Z","timestamp":1765421946000},"page":"114887","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Ferric carboxymaltose for third-trimester refractory anemia and perinatal outcomes: Retrospective cohort analysis"],"prefix":"10.1016","volume":"317","author":[{"given":"\u015eebnem","family":"Karag\u00fcn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamza","family":"Y\u0131ld\u0131z","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf","family":"Dal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sefanur Gamze","family":"Karaca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice Banu","family":"Atay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00fcr\u015fide \u00c7eviko\u011flu","family":"K\u0131ll\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayhan","family":"Co\u015fkun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.ejogrb.2025.114887_b0005","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1111\/ejh.13870","article-title":"The incidence, complications, and treatment of iron deficiency in pregnancy","volume":"109","author":"Benson","year":"2022","journal-title":"Eur J Haematol"},{"issue":"6","key":"10.1016\/j.ejogrb.2025.114887_b0010","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2016-1319","article-title":"Prenatal iron deficiency, neonatal ferritin, and infant cognitive function","volume":"138","author":"Mireku","year":"2016","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.ejogrb.2025.114887_b0015","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/bjh.16221","article-title":"UK guidelines on the management of iron deficiency in pregnancy","volume":"188","author":"Pavord","year":"2020","journal-title":"Br J Haematol"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.114887_b0020","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/imj.16602","article-title":"Iron optimisation in pregnancy: a haematology in obstetric and women's health collaborative consensus statement","volume":"55","author":"Clarke","year":"2025","journal-title":"Intern Med J"},{"issue":"1 Suppl","key":"10.1016\/j.ejogrb.2025.114887_b0025","doi-asserted-by":"crossref","first-page":"257s","DOI":"10.1093\/ajcn\/72.1.257S","article-title":"Iron requirements in pregnancy and strategies to meet them","volume":"72","author":"Bothwell","year":"2000","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0030","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1182\/hematology.2023000474","article-title":"Identifying and treating iron deficiency anemia in pregnancy","volume":"2023","author":"Lewkowitz","year":"2023","journal-title":"Hematology Am Soc Hematol Educ Program"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.114887_b0035","doi-asserted-by":"crossref","first-page":"495","DOI":"10.3945\/ajcn.115.107896","article-title":"Maternal anemia and risk of adverse birth and health outcomes in low- and middle-income countries: systematic review and meta-analysis","volume":"103","author":"Rahman","year":"2016","journal-title":"Am J Clin Nutr"},{"issue":"5","key":"10.1016\/j.ejogrb.2025.114887_b0040","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1111\/bjh.14961","article-title":"Association between maternal haemoglobin and stillbirth: acohort study among a multi-ethnic population in England","volume":"179","author":"Nair","year":"2017","journal-title":"Br J Haematol"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0045","doi-asserted-by":"crossref","first-page":"e76","DOI":"10.1542\/peds.2015-0491","article-title":"Prenatal hemoglobin levels and early cognitive and motor functions of one-year-old children","volume":"136","author":"Mireku","year":"2015","journal-title":"Pediatrics"},{"issue":"Suppl 6","key":"10.1016\/j.ejogrb.2025.114887_b0050","doi-asserted-by":"crossref","first-page":"1588s","DOI":"10.3945\/ajcn.117.155846","article-title":"Iron assessment to protect the developing brain","volume":"106","author":"Georgieff","year":"2017","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.114887_b0055","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.1097\/AOG.0000000000004477","article-title":"ACOG Practice Bulletin, Number 233","volume":"138","author":"Anemia in Pregnancy","year":"2021","journal-title":"Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0060","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s00277-019-03871-z","article-title":"Randomized controlled trial of twice-daily versus alternate-day oral iron therapy in the treatment of iron-deficiency anemia","volume":"99","author":"Kaundal","year":"2020","journal-title":"Ann Hematol"},{"key":"10.1016\/j.ejogrb.2025.114887_b0065","doi-asserted-by":"crossref","unstructured":"Pe\u00f1a-Rosas JP, De-Regil LM, Garcia-Casal MN, Dowswell T. Daily oral iron supplementation during pregnancy. The Cochrane database of systematic reviews. 2015;2015(7):Cd004736.","DOI":"10.1002\/14651858.CD004736.pub5"},{"issue":"8","key":"10.1016\/j.ejogrb.2025.114887_b0070","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1055\/s-0041-1740003","article-title":"Intravenous versus Oral Iron for Iron-Deficiency Anemia in Pregnancy (IVIDA): a Randomized Controlled Trial","volume":"39","author":"Lewkowitz","year":"2022","journal-title":"Am J Perinatol"},{"issue":"4","key":"10.1016\/j.ejogrb.2025.114887_b0075","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1007\/s00404-022-06768-x","article-title":"Intravenous ferric derisomaltose versus oral iron for persistent iron deficient pregnant women: a randomised controlled trial","volume":"308","author":"Hansen","year":"2023","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.ejogrb.2025.114887_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2025.01.037","article-title":"Single-dose intravenous iron vs oral iron for treatment of maternal iron deficiency anemia: a randomized clinical trial","author":"Derman","year":"2025","journal-title":"Am J Obstet Gynecol"},{"issue":"10388","key":"10.1016\/j.ejogrb.2025.114887_b0085","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1016\/S0140-6736(23)00278-7","article-title":"Ferric carboxymaltose versus standard-of-care oral iron to treat second-trimester anaemia in Malawian pregnant women: a randomised controlled trial","volume":"401","author":"Pasricha","year":"2023","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.114887_b0090","doi-asserted-by":"crossref","first-page":"e49","DOI":"10.1097\/AOG.0000000000002501","article-title":"190: Gestational Diabetes Mellitus","volume":"131","author":"ACOG Practice Bulletin No","year":"2018","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.114887_b0095","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1097\/AOG.0000000000004251","article-title":"ACOG Practice Bulletin, Number 227","volume":"137","author":"Fetal Growth Restriction","year":"2021","journal-title":"Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0100","first-page":"1","article-title":"202: Gestational hypertension and preeclampsia","volume":"133","author":"ACOG Practice Bulletin No","year":"2019","journal-title":"Obstet Gynecol"},{"issue":"6","key":"10.1016\/j.ejogrb.2025.114887_b0105","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1097\/AOG.0000000000004612","article-title":"Prediction and Prevention of spontaneous preterm birth: ACOG practice bulletin, number 234","volume":"138","author":"Hoffman","year":"2021","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ejogrb.2025.114887_b0110","doi-asserted-by":"crossref","DOI":"10.61622\/rbgo\/2024AO21","article-title":"A meta-analysis of ferric carboxymaltose versus other intravenous iron preparations for the management of iron deficiency anemia during pregnancy","volume":"46","author":"Gupte","year":"2024","journal-title":"Rev Bras Ginecol Obstet"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0115","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s12884-019-2200-3","article-title":"Comparison of ferric carboxymaltose and iron sucrose complex for treatment of iron deficiency anemia in pregnancy- randomised controlled trial","volume":"19","author":"Jose","year":"2019","journal-title":"BMC Pregnancy Childbirth"},{"issue":"8","key":"10.1016\/j.ejogrb.2025.114887_b0120","doi-asserted-by":"crossref","first-page":"367","DOI":"10.5694\/mja2.50308","article-title":"Intravenous or oral iron for treating iron deficiency anaemia during pregnancy: systematic review and meta-analysis","volume":"211","author":"Qassim","year":"2019","journal-title":"Med J Aust"},{"issue":"15","key":"10.1016\/j.ejogrb.2025.114887_b0125","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1080\/14767058.2018.1555811","article-title":"The relationship between maternal anemia during pregnancy with preterm birth: a systematic review and meta-analysis","volume":"33","author":"Rahmati","year":"2020","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"4","key":"10.1016\/j.ejogrb.2025.114887_b0130","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1515\/jpm-2020-0379","article-title":"Gestational iron deficiency anemia is associated with preterm birth, fetal growth restriction, and postpartum infections","volume":"49","author":"Kemppinen","year":"2021","journal-title":"J Perinat Med"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0135","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/s41430-019-0464-3","article-title":"Anaemia and iron deficiency in pregnancy and adverse perinatal outcomes in Southern India","volume":"74","author":"Finkelstein","year":"2020","journal-title":"Eur J Clin Nutr"},{"issue":"9","key":"10.1016\/j.ejogrb.2025.114887_b0140","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1111\/aogs.14607","article-title":"Iron supplements in pregnant women with normal iron status: a systematic review and meta-analysis","volume":"102","author":"Hansen","year":"2023","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"3","key":"10.1016\/j.ejogrb.2025.114887_b0145","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s00404-020-05817-7","article-title":"Comparison of the maternal and neonatal outcomes of pregnant women whose anemia was not corrected before delivery and pregnant women who were treated with intravenous iron in the third trimester","volume":"303","author":"Oskovi-Kaplan","year":"2021","journal-title":"Arch Gynecol Obstet"},{"issue":"10","key":"10.1016\/j.ejogrb.2025.114887_b0150","doi-asserted-by":"crossref","first-page":"e1649","DOI":"10.1016\/S2214-109X(24)00239-0","article-title":"Intravenous versus oral iron for anaemia among pregnant women in Nigeria (IVON): an open-label, randomised controlled trial","volume":"12","author":"Afolabi","year":"2024","journal-title":"Lancet Glob Health"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0155","doi-asserted-by":"crossref","first-page":"39","DOI":"10.4103\/jcn.JCN_94_18","article-title":"Characteristics and predictors of outcome of care of preterm newborns in resource constraints setting, Maiduguri","volume":"8","author":"Bello","year":"2019","journal-title":"Northeastern Nigeria Journal of Clinical Neonatology"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0160","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/s41591-024-03385-w","article-title":"Ferric carboxymaltose for anemia in late pregnancy: a randomized controlled trial","volume":"31","author":"Pasricha","year":"2025","journal-title":"Nat Med"},{"issue":"12","key":"10.1016\/j.ejogrb.2025.114887_b0165","doi-asserted-by":"crossref","first-page":"e1706","DOI":"10.1016\/S2214-109X(19)30427-9","article-title":"Safety and effectiveness of intravenous iron sucrose versus standard oral iron therapy in pregnant women with moderate-to-severe anaemia in India: a multicentre, open-label, phase 3, randomised, controlled trial","volume":"7","author":"Neogi","year":"2019","journal-title":"Lancet Glob Health"},{"issue":"4","key":"10.1016\/j.ejogrb.2025.114887_b0170","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1515\/jpm-2016-0050","article-title":"Ferric carboxymaltose vs. oral iron in the treatment of pregnant women with iron deficiency anemia: an international, open-label, randomized controlled trial (FER-ASAP)","volume":"45","author":"Breymann","year":"2017","journal-title":"J Perinat Med"},{"issue":"4","key":"10.1016\/j.ejogrb.2025.114887_b0175","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1053\/j.seminhematol.2018.04.006","article-title":"A prospective randomised controlled trial of a single intravenous infusion of ferric carboxymaltose vs single intravenous iron polymaltose or daily oral ferrous sulphate in the treatment of iron deficiency anaemia in pregnancy","volume":"55","author":"Khalafallah","year":"2018","journal-title":"Semin Hematol"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.114887_b0180","doi-asserted-by":"crossref","DOI":"10.3390\/nu12020491","article-title":"Vitamin and mineral supplementation during pregnancy on maternal, birth, child health and development outcomes in low- and middle-income countries: a systematic review and meta-analysis","volume":"12","author":"Oh","year":"2020","journal-title":"Nutrients"},{"issue":"6","key":"10.1016\/j.ejogrb.2025.114887_b0185","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1111\/ejh.14298","article-title":"Perinatal outcomes following intravenous iron for treatment of iron deficiency with and without anemia","volume":"113","author":"Ryan","year":"2024","journal-title":"Eur J Haematol"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0190","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/s12884-024-06349-7","article-title":"Neonatal outcomes in the surgical management of placenta accreta spectrum disorders: a retrospective single-center observational study from 468 Vietnamese pregnancies beyond 28 weeks of gestation","volume":"24","author":"Nguyen","year":"2024","journal-title":"BMC Pregnancy Childbirth"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.114887_b0195","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1002\/ijgo.15220","article-title":"Modified one-step conservative uterine surgery (MOSCUS) versus cesarean hysterectomy in the management of placenta accreta spectrum: a single-center retrospective analysis based on 619 Vietnamese pregnant women","volume":"165","author":"Vuong","year":"2024","journal-title":"Int J Gynaecol Obstet"},{"issue":"1","key":"10.1016\/j.ejogrb.2025.114887_b0200","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1186\/s12884-025-07491-6","article-title":"The effect of preoperative intravenous iron administration on patient outcomes in the spectrum of placenta accreta: a retrospective case-control study","volume":"25","author":"Zeki Nessar","year":"2025","journal-title":"BMC Pregnancy Childbirth"},{"issue":"2","key":"10.1016\/j.ejogrb.2025.114887_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajogmf.2022.100569","article-title":"The impact of response to iron therapy on maternal and neonatal outcomes among pregnant women with anemia","volume":"4","author":"Detlefs","year":"2022","journal-title":"Am J Obstet Gynecol MFM"},{"issue":"12","key":"10.1016\/j.ejogrb.2025.114887_b0210","doi-asserted-by":"crossref","first-page":"e2049","DOI":"10.1016\/S2214-109X(24)00380-2","article-title":"Postpartum maternal and infant haematological effects of second-trimester ferric carboxymaltose versus standard-of-care oral iron in Malawi: longitudinal follow-up of a randomised controlled trial","volume":"12","author":"Mzembe","year":"2024","journal-title":"Lancet Glob Health"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211525011637?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211525011637?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T12:00:45Z","timestamp":1767096045000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211525011637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":42,"alternative-id":["S0301211525011637"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2025.114887","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ferric carboxymaltose for third-trimester refractory anemia and perinatal outcomes: Retrospective cohort analysis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2025.114887","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114887"}}