{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T19:40:32Z","timestamp":1790019632658,"version":"4.0.1"},"reference-count":113,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejog.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.ejogrb.2026.114941","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:17:50Z","timestamp":1767658670000},"page":"114941","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Microbiota and infertility: a translational review of mechanisms and clinical applications in assisted reproduction"],"prefix":"10.1016","volume":"318","author":[{"given":"Bixiu","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaru","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lang","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejogrb.2026.114941_b0005","doi-asserted-by":"crossref","unstructured":"1. Eisenberg ML, Esteves SC, Lamb DJ, Hotaling JM, Giwercman A, Hwang K, Cheng YS: Male infertility. Nature reviews Disease primers 2023, 9(1):49.","DOI":"10.1038\/s41572-023-00459-w"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0010","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/jama.2021.4788","article-title":"Diagnosis and management of infertility: a review","volume":"326","author":"Carson","year":"2021","journal-title":"J Am Med Assoc"},{"issue":"6641","key":"10.1016\/j.ejogrb.2026.114941_b0015","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1126\/science.adf7760","article-title":"Understanding the genetics of human infertility","volume":"380","author":"Sang","year":"2023","journal-title":"Science (New York, NY)"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0020","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/s41585-023-00816-0","article-title":"Improved phenotypic classification of male infertility to promote discovery of genetic causes","volume":"21","author":"Wyrwoll","year":"2024","journal-title":"Nat Rev Urol"},{"issue":"6","key":"10.1016\/j.ejogrb.2026.114941_b0025","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s40618-022-01752-3","article-title":"Human genital tracts microbiota: dysbiosis crucial for infertility","volume":"45","author":"Venneri","year":"2022","journal-title":"J Endocrinol Invest"},{"issue":"10","key":"10.1016\/j.ejogrb.2026.114941_b0030","article-title":"Microbial dysbiosis and male infertility: understanding the impact and exploring therapeutic interventions","volume":"13","author":"Kaltsas","year":"2023","journal-title":"J Personal Med"},{"key":"10.1016\/j.ejogrb.2026.114941_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2024.104418","article-title":"The role of reproductive tract microbiota in gynecological health and diseases","volume":"167","author":"Wang","year":"2025","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0040","article-title":"Interaction between chronic endometritis caused endometrial microbiota disorder and endometrial immune environment change in recurrent implantation failure","volume":"12","author":"Chen","year":"2021","journal-title":"Front Immunol"},{"issue":"9","key":"10.1016\/j.ejogrb.2026.114941_b0045","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines11092391","article-title":"Chronic endometritis and uterine endometrium microbiota in recurrent implantation failure and recurrent pregnancy loss","volume":"11","author":"Takimoto","year":"2023","journal-title":"Biomedicines"},{"key":"10.1016\/j.ejogrb.2026.114941_b0050","doi-asserted-by":"crossref","unstructured":"Toson B, Simon C, Moreno I: The Endometrial Microbiome and Its Impact on Human Conception. International journal of molecular sciences 2022, 23(1).","DOI":"10.3390\/ijms23010485"},{"issue":"6","key":"10.1016\/j.ejogrb.2026.114941_b0055","doi-asserted-by":"crossref","DOI":"10.3390\/metabo15060390","article-title":"Gut microbiome dysbiosis and its impact on reproductive health: mechanisms and clinical applications","volume":"15","author":"Moustakli","year":"2025","journal-title":"Metabolites"},{"key":"10.1016\/j.ejogrb.2026.114941_b0060","article-title":"Role of the gut microbiota in the pathogenesis of endometriosis: a review","volume":"15","author":"Guo","year":"2024","journal-title":"Front Microbiol"},{"issue":"5","key":"10.1016\/j.ejogrb.2026.114941_b0065","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1007\/s12602-024-10223-5","article-title":"Gut microbiota and polycystic ovary syndrome (PCOS): understanding the pathogenesis and the role of probiotics as a therapeutic strategy","volume":"16","author":"Salehi","year":"2024","journal-title":"Probiotics Antimicrob Proteins"},{"key":"10.1016\/j.ejogrb.2026.114941_b0070","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2024.1371667","article-title":"Gut microbiota is involved in male reproductive function: a review","volume":"15","author":"Lv","year":"2024","journal-title":"Front Microbiol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0075","doi-asserted-by":"crossref","unstructured":"Kaltsas A, Giannakodimos I, Markou E, Stavropoulos M, Deligiannis D, Kratiras Z, Chrisofos M: The Androbactome and the Gut Microbiota-Testis Axis: A Narrative Review of Emerging Insights into Male Fertility. International journal of molecular sciences 2025, 26(13).","DOI":"10.3390\/ijms26136211"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0080","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1093\/humupd\/dmab035","article-title":"The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain","volume":"28","author":"Salliss","year":"2021","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ejogrb.2026.114941_b0085","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.698840","article-title":"Alterations of vaginal microbiota in women with infertility and chlamydia trachomatis infection","volume":"11","author":"Chen","year":"2021","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0090","doi-asserted-by":"crossref","first-page":"350","DOI":"10.3389\/fcimb.2020.00350","article-title":"Structural variations of vaginal and endometrial microbiota: hints on female infertility","volume":"10","author":"Riganelli","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0095","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s12905-022-01681-6","article-title":"Distinct gut and vaginal microbiota profile in women with recurrent implantation failure and unexplained infertility","volume":"22","author":"Patel","year":"2022","journal-title":"BMC Womens Health"},{"key":"10.1016\/j.ejogrb.2026.114941_b0100","doi-asserted-by":"crossref","unstructured":"Vanstokstraeten R, Callewaert E, Blotwijk S, Rombauts E, Cromb\u00e9 F, Emmerechts K, Soetens O, Vandoorslaer K, De Geyter D, Allonsius C et al: Comparing Vaginal and Endometrial Microbiota Using Culturomics: Proof of Concept. International journal of molecular sciences 2023, 24(6).","DOI":"10.3390\/ijms24065947"},{"issue":"6","key":"10.1016\/j.ejogrb.2026.114941_b0105","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01650-23","article-title":"Longitudinal analysis of vaginal microbiota during IVF fresh embryo transfer and in early pregnancy","volume":"11","author":"V\u00e4in\u00e4m\u00f6","year":"2023","journal-title":"Microbiol Spectrum"},{"issue":"3","key":"10.1016\/j.ejogrb.2026.114941_b0110","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ajog.2020.10.019","article-title":"Bacterial vaginosis and its association with infertility, endometritis, and pelvic inflammatory disease","volume":"224","author":"Ravel","year":"2021","journal-title":"Am J Obstet Gynecol"},{"issue":"20","key":"10.1016\/j.ejogrb.2026.114941_b0115","first-page":"347","article-title":"Bacterial vaginosis-vaginal polymicrobial biofilms and dysbiosis","volume":"120","author":"Swidsinski","year":"2023","journal-title":"Deutsches Arzteblatt Int"},{"key":"10.1016\/j.ejogrb.2026.114941_b0120","doi-asserted-by":"crossref","unstructured":"Chudzicka-Struga\u0142a I, Go\u0142\u0119biewska I, Banaszewska B, Trzci\u0144ski M, Brudecki G, Elamin W, Zwo\u017adziak B: Bacterial Vaginosis (BV) and Vaginal Microbiome Disorders in Women Suffering from Polycystic Ovary Syndrome (PCOS). Diagnostics (Basel, Switzerland) 2024, 14(4).","DOI":"10.3390\/diagnostics14040404"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0125","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/s10815-023-03000-w","article-title":"Bacterial vaginosis in a subfertile population undergoing fertility treatments: a prospective cohort study","volume":"41","author":"van den Tweel","year":"2024","journal-title":"J Assist Reprod Genet"},{"issue":"7","key":"10.1016\/j.ejogrb.2026.114941_b0130","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1111\/aogs.14598","article-title":"Lactobacillus crispatus-dominated vaginal microbiome and acinetobacter-dominated seminal microbiome support beneficial ART outcome","volume":"102","author":"Koort","year":"2023","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ejogrb.2026.114941_b0135","doi-asserted-by":"crossref","unstructured":"Gao X, Louwers YV, Laven JSE, Schoenmakers S: Clinical Relevance of Vaginal and Endometrial Microbiome Investigation in Women with Repeated Implantation Failure and Recurrent Pregnancy Loss. International journal of molecular sciences 2024, 25(1).","DOI":"10.3390\/ijms25010622"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0140","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12941-024-00710-6","article-title":"Chronic endometritis and the endometrial microbiota: implications for reproductive success in patients with recurrent implantation failure","volume":"23","author":"Zhang","year":"2024","journal-title":"Ann Clin Microbiol Antimicrob"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0145","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1186\/s12958-024-01274-y","article-title":"Vaginal and endometrial microbiome dysbiosis associated with adverse embryo transfer outcomes","volume":"22","author":"Su","year":"2024","journal-title":"Reproduct Biol Endocrinol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0150","doi-asserted-by":"crossref","unstructured":"Zhang R, Wang M, Zhong J, Xue H: Altered Endometrial Microbiota Profile Is Associated With Poor Endometrial Receptivity of Repeated Implantation Failure. American journal of reproductive immunology (New York, NY : 1989) 2024, 92(5):e70005.","DOI":"10.1111\/aji.70005"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0155","first-page":"267","article-title":"Endometrial and vaginal microbiomes influence assisted reproductive technology outcomes","volume":"27","author":"Miyagi","year":"2023","journal-title":"JBRA Assist Reproduct"},{"issue":"18","key":"10.1016\/j.ejogrb.2026.114941_b0160","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10184063","article-title":"Impact of the vaginal and endometrial microbiome pattern on assisted reproduction outcomes","volume":"10","author":"Diaz-Mart\u00ednez","year":"2021","journal-title":"J Clin Med"},{"issue":"9","key":"10.1016\/j.ejogrb.2026.114941_b0165","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1007\/s10815-022-02573-2","article-title":"Interaction between endometrial microbiota and host gene regulation in recurrent implantation failure","volume":"39","author":"Chen","year":"2022","journal-title":"J Assist Reprod Genet"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0170","doi-asserted-by":"crossref","first-page":"30508","DOI":"10.1038\/s41598-024-82466-9","article-title":"Differential characteristics of vaginal versus endometrial microbiota in IVF patients","volume":"14","author":"Polifke","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.ejogrb.2026.114941_b0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2022.103782","article-title":"The endometrial microbiota profile influenced pregnancy outcomes in patients with repeated implantation failure: a retrospective study","volume":"155","author":"Zou","year":"2023","journal-title":"J Reprod Immunol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0180","doi-asserted-by":"crossref","unstructured":"Tomaiuolo R, Veneruso I, Cariati F, D'Argenio V: Microbiota and Human Reproduction: The Case of Male Infertility. High-throughput 2020, 9(2).","DOI":"10.3390\/ht9020010"},{"key":"10.1016\/j.ejogrb.2026.114941_b0185","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2023.1228693","article-title":"Male infertility risk and gut microbiota: a Mendelian randomization study","volume":"14","author":"Fu","year":"2023","journal-title":"Front Microbiol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0190","doi-asserted-by":"crossref","unstructured":"Mowla S, Farahani L, Tharakan T, Davies R, Correia GDS, Lee YS, Kundu S, Khanjani S, Sindi E, Rai R et al: Characterisation and comparison of semen microbiota and bacterial load in men with infertility, recurrent miscarriage, or proven fertility. eLife 2025, 13.","DOI":"10.7554\/eLife.96090"},{"issue":"4","key":"10.1016\/j.ejogrb.2026.114941_b0195","doi-asserted-by":"crossref","first-page":"353","DOI":"10.4103\/aja202169","article-title":"Semen microbiota and cytokines of healthy and infertile men","volume":"24","author":"Bukharin","year":"2022","journal-title":"Asian J Androl"},{"issue":"S2","key":"10.1016\/j.ejogrb.2026.114941_b0200","doi-asserted-by":"crossref","first-page":"82","DOI":"10.33594\/000000802","article-title":"Oxidative stress, ANTIOXIDANTS, GUT MICROBIOTA AND MALE FERTILity","volume":"59","author":"Kurhaluk","year":"2025","journal-title":"Cell Physiol Biochem"},{"issue":"6","key":"10.1016\/j.ejogrb.2026.114941_b0205","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/j.eururo.2021.01.014","article-title":"Functional and taxonomic dysbiosis of the gut, urine, and semen microbiomes in male infertility","volume":"79","author":"Lundy","year":"2021","journal-title":"Eur Urol"},{"issue":"15","key":"10.1016\/j.ejogrb.2026.114941_b0210","doi-asserted-by":"crossref","DOI":"10.3390\/cells13151275","article-title":"Male tract microbiota and male infertility","volume":"13","author":"Grande","year":"2024","journal-title":"Cells"},{"issue":"5","key":"10.1016\/j.ejogrb.2026.114941_b0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.rbmo.2025.105056","article-title":"Genital microbiota in infertile couples","volume":"51","author":"Baud","year":"2025","journal-title":"Reprod Biomed Online"},{"issue":"6","key":"10.1016\/j.ejogrb.2026.114941_b0220","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1007\/s11596-024-2931-x","article-title":"Causal link between gut microbiota and infertility: a two-sample bidirectional mendelian randomization study","volume":"44","author":"Zhang","year":"2024","journal-title":"Curr Med Sci"},{"key":"10.1016\/j.ejogrb.2026.114941_b0225","doi-asserted-by":"crossref","unstructured":"Kukaev E, Kirillova E, Tokareva A, Rimskaya E, Starodubtseva N, Chernukha G, Priputnevich T, Frankevich V, Sukhikh G: Impact of Gut Microbiota and SCFAs in the Pathogenesis of PCOS and the Effect of Metformin Therapy. International journal of molecular sciences 2024, 25(19).","DOI":"10.3390\/ijms251910636"},{"key":"10.1016\/j.ejogrb.2026.114941_b0230","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2025.1549499","article-title":"Systematic review of gut microbiota composition, metabolic alterations, and the effects of treatments on PCOS and gut microbiota across human and animal studies","volume":"16","author":"Hanna","year":"2025","journal-title":"Front Microbiol"},{"issue":"8","key":"10.1016\/j.ejogrb.2026.114941_b0235","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1038\/s41591-019-0509-0","article-title":"Gut microbiota-bile acid-interleukin-22 axis orchestrates polycystic ovary syndrome","volume":"25","author":"Qi","year":"2019","journal-title":"Nat Med"},{"key":"10.1016\/j.ejogrb.2026.114941_b0240","article-title":"Association between the dietary index for gut microbiota and female infertility: a cross-sectional study of NHANES 2013-2018","volume":"12","author":"Zhang","year":"2025","journal-title":"Front Nutr"},{"issue":"8","key":"10.1016\/j.ejogrb.2026.114941_b0245","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.04291-23","article-title":"Dysbiotic alteration in the fecal microbiota of patients with polycystic ovary syndrome","volume":"12","author":"Chen","year":"2024","journal-title":"Microbiol Spectrum"},{"issue":"7","key":"10.1016\/j.ejogrb.2026.114941_b0250","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1007\/s43032-023-01440-4","article-title":"Gut microbiome composition in polycystic ovary syndrome adult women: a systematic review and meta-analysis of observational studies","volume":"31","author":"Zhu","year":"2024","journal-title":"Reproduct Sci"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0255","doi-asserted-by":"crossref","first-page":"11426","DOI":"10.1038\/s41598-023-38624-6","article-title":"A two-sample mendelian randomization analysis investigates associations between gut microbiota and infertility","volume":"13","author":"Li","year":"2023","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.ejogrb.2026.114941_b0260","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02360-23","article-title":"Alteration in gut mycobiota of patients with polycystic ovary syndrome","volume":"11","author":"Chen","year":"2023","journal-title":"Microbiol Spectrum"},{"key":"10.1016\/j.ejogrb.2026.114941_b0265","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1368334","article-title":"Inflammatory cytokines may mediate the causal relationship between gut microbiota and male infertility: a bidirectional, mediating, multivariate Mendelian randomization study","volume":"15","author":"Zou","year":"2024","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0270","doi-asserted-by":"crossref","unstructured":"Bau\u0219ic AIG, Scurtu F, Manu A, Matasariu DR, Br\u0103til\u0103 E: Gut Microbiota Dysbiosis in Endometriosis: A Potential Link to Inflammation and Disease Progression. International journal of molecular sciences 2025, 26(11).","DOI":"10.3390\/ijms26115144"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0275","article-title":"The impact of the microbiota-gut-brain axis on endometriosis-associated symptoms: mechanisms and opportunities for personalised management strategies","volume":"5","author":"Hearn-Yeates","year":"2024","journal-title":"Reproduct Fertility"},{"key":"10.1016\/j.ejogrb.2026.114941_b0280","doi-asserted-by":"crossref","DOI":"10.1177\/03915603251358953","article-title":"Bugs and babies: how gut microbiota affect infertility? A narrative Review","author":"Azmy Nabeh","year":"2025","journal-title":"Urologia"},{"issue":"8","key":"10.1016\/j.ejogrb.2026.114941_b0285","doi-asserted-by":"crossref","first-page":"3673","DOI":"10.7150\/thno.91873","article-title":"Transcriptomic profiling of murine GnRH neurons reveals developmental trajectories linked to human reproduction and infertility","volume":"15","author":"Zouaghi","year":"2025","journal-title":"Theranostics"},{"issue":"10","key":"10.1016\/j.ejogrb.2026.114941_b0290","doi-asserted-by":"crossref","DOI":"10.3390\/biom14101325","article-title":"Endometrial dysbiosis: a possible association with estrobolome alteration","volume":"14","author":"Scarf\u00f2","year":"2024","journal-title":"Biomolecules"},{"issue":"6","key":"10.1016\/j.ejogrb.2026.114941_b0295","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/s41419-023-05866-1","article-title":"METTL3-dependent m(6)A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling","volume":"14","author":"Wan","year":"2023","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.ejogrb.2026.114941_b0300","doi-asserted-by":"crossref","unstructured":"Teveroni E, Di Nicuolo F, Vergani E, Bruno C, Maulucci G, Bianchetti G, Astorri AL, Grande G, Gervasoni J, Santucci L et al: Short-Chain Fatty Acids Modulate Sperm Migration through Olfactory Receptor 51E2 Activity. International journal of molecular sciences 2022, 23(21).","DOI":"10.3390\/ijms232112726"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0305","article-title":"Identification of distinct stool metabolites in women with endometriosis for non-invasive diagnosis and potential for microbiota-based therapies","volume":"6","author":"Talwar","year":"2025","journal-title":"Med (New York, NY)"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0310","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/cen.14399","article-title":"A review of the pathophysiology of functional hypothalamic amenorrhoea in women subject to psychological stress, disordered eating, excessive exercise or a combination of these factors","volume":"95","author":"Morrison","year":"2021","journal-title":"Clin Endocrinol"},{"issue":"4","key":"10.1016\/j.ejogrb.2026.114941_b0315","doi-asserted-by":"crossref","first-page":"398","DOI":"10.4103\/aja202172","article-title":"Semen microbiota in normal and leukocytospermic males","volume":"24","author":"Yao","year":"2022","journal-title":"Asian J Androl"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0320","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms9010039","article-title":"Lactobacillus iners and gasseri, Prevotella bivia and HPV belong to the microbiological signature negatively affecting human reproduction","volume":"9","author":"Campisciano","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.ejogrb.2026.114941_b0325","article-title":"Role of lactobacillus in female infertility via modulating sperm agglutination and immobilization","volume":"10","author":"Zhang","year":"2020","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0330","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1125640","article-title":"Analysis of the microbiota composition in the genital tract of infertile patients with chronic endometritis or endometrial polyps","volume":"13","author":"Liang","year":"2023","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0335","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.937157","article-title":"Seminal microbiota of idiopathic infertile patients and its relationship with sperm DNA integrity","volume":"10","author":"Garcia-Segura","year":"2022","journal-title":"Front Cell Dev Biol"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0340","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s12958-024-01273-z","article-title":"Molecular regulation of DNA damage and repair in female infertility: a systematic review","volume":"22","author":"Xu","year":"2024","journal-title":"Reproduct Biol Endocrinol"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0345","doi-asserted-by":"crossref","first-page":"50","DOI":"10.5653\/cerm.2020.03972","article-title":"High mRNA expression of GABA receptors in human sperm with oligoasthenoteratozoospermia and teratozoospermia and its association with sperm parameters and intracytoplasmic sperm injection outcomes","volume":"48","author":"Kaewman","year":"2021","journal-title":"Clin Exp Reprod Med"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0350","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1186\/s13048-024-01573-3","article-title":"Bile acids in follicular fluid: potential new therapeutic targets and predictive markers for women with diminished ovarian reserve","volume":"17","author":"Ding","year":"2024","journal-title":"J Ovarian Res"},{"key":"10.1016\/j.ejogrb.2026.114941_b0355","doi-asserted-by":"crossref","unstructured":"Bracewell-Milnes T, Saso S, Nikolaou D, Norman-Taylor J, Johnson M, Thum MY: Investigating the effect of an abnormal cervico-vaginal and endometrial microbiome on assisted reproductive technologies: A systematic review. American journal of reproductive immunology (New York, NY : 1989) 2018, 80(5):e13037.","DOI":"10.1111\/aji.13037"},{"key":"10.1016\/j.ejogrb.2026.114941_b0360","doi-asserted-by":"crossref","unstructured":"Vitale SG, Ferrari F, Ciebiera M, Zgliczy\u0144ska M, Rapisarda AMC, Vecchio GM, Pino A, Angelico G, Knafel A, Riemma G et al: The Role of Genital Tract Microbiome in Fertility: A Systematic Review. International journal of molecular sciences 2021, 23(1).","DOI":"10.3390\/ijms23010180"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0365","doi-asserted-by":"crossref","first-page":"3444","DOI":"10.1038\/s41598-023-30591-2","article-title":"The endometrial microbiota of women with or without a live birth within 12\u2002months after a first failed IVF\/ICSI cycle","volume":"13","author":"Bui","year":"2023","journal-title":"Sci Rep"},{"key":"10.1016\/j.ejogrb.2026.114941_b0370","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2023.104138","article-title":"Impact of Lactobacillus in the uterine microbiota on in vitro fertilization outcomes","volume":"160","author":"Kadogami","year":"2023","journal-title":"J Reprod Immunol"},{"issue":"8","key":"10.1016\/j.ejogrb.2026.114941_b0375","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1007\/s10815-022-02558-1","article-title":"Does antibiotic therapy for chronic endometritis improve clinical outcomes of patients with recurrent implantation failure in subsequent IVF cycles? a systematic review and meta-analysis","volume":"39","author":"Cheng","year":"2022","journal-title":"J Assist Reprod Genet"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0380","doi-asserted-by":"crossref","first-page":"142","DOI":"10.5653\/cerm.2020.04203","article-title":"Staphylococcus saprophyticus and Escherichia coli: Tracking from sperm fertility potential to assisted reproductive outcomes","volume":"48","author":"Ghasemian","year":"2021","journal-title":"Clin Exp Reprod Med"},{"issue":"13","key":"10.1016\/j.ejogrb.2026.114941_b0385","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1111\/1471-0528.16782","article-title":"The vaginal microbiota composition of women undergoing assisted reproduction: a prospective cohort study","volume":"128","author":"Karaer","year":"2021","journal-title":"BJOG"},{"issue":"3","key":"10.1016\/j.ejogrb.2026.114941_b0390","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/jog.12898","article-title":"Gross motor function and general development of babies born after assisted reproductive technology","volume":"42","author":"Hashimoto","year":"2016","journal-title":"J Obstet Gynaecol Res"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0395","first-page":"306","article-title":"Sperm DNA Fragmentation: causes, evaluation and management in male infertility","volume":"28","author":"Andrabi","year":"2024","journal-title":"JBRA Assisted Reproduct"},{"issue":"3","key":"10.1016\/j.ejogrb.2026.114941_b0400","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1556\/030.2024.02323","article-title":"Characterization of the vaginal microbiota in\u2002infertile women with repeated implantation failure","volume":"71","author":"Liu","year":"2024","journal-title":"Acta Microbiol Immunol Hung"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0405","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.fertnstert.2024.08.326","article-title":"Preimplantation genetic testing for aneuploidy in unexplained recurrent pregnancy loss: a systematic review and meta-analysis","volume":"123","author":"Mumusoglu","year":"2025","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0410","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1080\/14647273.2019.1686775","article-title":"Comparison of the assisted reproductive technology outcomes between conventional IVF and ICSI with donor oocytes in normozoospermic patients","volume":"25","author":"Ten","year":"2022","journal-title":"Hum Fertil (Camb)"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0415","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2020.1794466","article-title":"Alternations of gut microbiota composition in neonates conceived by assisted reproductive technology and its relation to infant growth","volume":"12","author":"Lu","year":"2020","journal-title":"Gut Microbes"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0420","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.rbmo.2011.10.011","article-title":"Cryptic sperm defects may be the cause for total fertilization failure in oocyte donor cycles","volume":"24","author":"Goudakou","year":"2012","journal-title":"Reprod Biomed Online"},{"issue":"11","key":"10.1016\/j.ejogrb.2026.114941_b0425","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0207684","article-title":"Impact of asymptomatic genital tract infections on in vitro Fertilization (IVF) outcome","volume":"13","author":"Ricci","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.ejogrb.2026.114941_b0430","doi-asserted-by":"crossref","unstructured":"Boychuk AV, Kotsabyn NV, Yakymchuk JB, Nikitina IM: Pregravid preparation of women with chronic endometritis in IVF cycles. Wiadomosci lekarskie (Warsaw, Poland : 1960) 2024, 77(1):25-28.","DOI":"10.36740\/WLek202401103"},{"issue":"4","key":"10.1016\/j.ejogrb.2026.114941_b0435","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1093\/humrep\/dew026","article-title":"Abnormal vaginal microbiota may be associated with poor reproductive outcomes: a prospective study in IVF patients","volume":"31","author":"Haahr","year":"2016","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.ejogrb.2026.114941_b0440","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1097\/GCO.0000000000000953","article-title":"Vaginal dysbiosis - the association with reproductive outcomes in IVF patients: a systematic review and meta-analysis","volume":"36","author":"Maksimovic Celicanin","year":"2024","journal-title":"Curr Opin Obstet Gynecol"},{"issue":"10","key":"10.1016\/j.ejogrb.2026.114941_b0445","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.25122\/jml-2023-0056","article-title":"Probiotics and NLRP3 mRNA inflammasome levels in women with endometriosis-related infertility undergoing assisted reproductive technologies","volume":"16","author":"Bakun","year":"2023","journal-title":"J Med Life"},{"issue":"3","key":"10.1016\/j.ejogrb.2026.114941_b0450","doi-asserted-by":"crossref","first-page":"234","DOI":"10.36740\/Merkur202303108","article-title":"A new approach to assisted reproductive technologies preparation in women with endometriosis associated infertility using probiotics","volume":"51","author":"Bakun","year":"2023","journal-title":"Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego"},{"key":"10.1016\/j.ejogrb.2026.114941_b0455","doi-asserted-by":"crossref","unstructured":"Bakun OV, Koval HD, Dudka YA, Oshchepkova IA, Makoviichuk KY: INFLUENCE OF PROBIOTICS ON THE MESOTHELIN LEVEL IN WOMEN WITH ENDOMETRIOSIS ASSOCIATED WITH INFERTILITY IN COMPLEX PREPARATION FOR ASSISTED REPRODUCTIVE TECHNOLOGIES. Wiadomosci lekarskie (Warsaw, Poland : 1960) 2023, 76(11):2455-2459.","DOI":"10.36740\/WLek202311118"},{"issue":"3","key":"10.1016\/j.ejogrb.2026.114941_b0460","article-title":"Expert opinion: place in therapy of probiotics in infertility and recurrent implantation failure","volume":"17","author":"Patki","year":"2025","journal-title":"Cureus"},{"issue":"5","key":"10.1016\/j.ejogrb.2026.114941_b0465","first-page":"485","article-title":"Myo-inositol: from induction of ovulation to menopausal disorder management","volume":"67","author":"Gullo","year":"2015","journal-title":"Minerva Ginecol"},{"issue":"4","key":"10.1016\/j.ejogrb.2026.114941_b0470","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1080\/09513590.2016.1254613","article-title":"Myo-inositol and melatonin in the menopausal transition","author":"D'Anna","year":"2017","journal-title":"Gynecol Endocrinol"},{"issue":"4","key":"10.1016\/j.ejogrb.2026.114941_b0475","first-page":"1241","article-title":"Does Alpha-lipoic acid improve effects on polycystic ovary syndrome?","volume":"26","author":"Lagan\u00e0","year":"2022","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0480","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1024\/0300-9831\/a000691","article-title":"The role of vitamin D in metabolic and reproductive disturbances of polycystic ovary syndrome: a narrative mini-review","volume":"92","author":"Menichini","year":"2022","journal-title":"Int J Vitamin Nutr Res Int"},{"issue":"11","key":"10.1016\/j.ejogrb.2026.114941_b0485","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1007\/s10815-017-1010-7","article-title":"GnRH antagonist administered twice the day before hCG trigger combined with a step-down protocol may prevent OHSS in IVF\/ICSI antagonist cycles at risk for OHSS without affecting the reproductive outcomes: a prospective randomized control trial","volume":"34","author":"Prapas","year":"2017","journal-title":"J Assist Reprod Genet"},{"key":"10.1016\/j.ejogrb.2026.114941_b0490","doi-asserted-by":"crossref","unstructured":"Gullo G, Zaami S, Streva AV, Burgio S, Billone V, Kotlik Y, Chitoran E, Ganduscio S, Baglio G, Perino A et al: Multivitamin Supplementation and Fertility Outcome: A Retrospective Single-Center Cohort Study and the Clinical and Medicolegal Value of Nutritional Counseling. Life (Basel, Switzerland) 2025, 15(1).","DOI":"10.3390\/life15010048"},{"issue":"9","key":"10.1016\/j.ejogrb.2026.114941_b0495","doi-asserted-by":"crossref","DOI":"10.3390\/jcm14092923","article-title":"The role of the genital tract microbiome in human fertility: a literature review","volume":"14","author":"Gullo","year":"2025","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0500","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12978-023-01652-6","article-title":"Effectiveness of a mixed lifestyle program in couples undergoing assisted reproductive technology: a study protocol","volume":"20","author":"Malekpour","year":"2023","journal-title":"Reprod Health"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0505","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.fertnstert.2021.10.021","article-title":"Paternal adherence to healthy dietary patterns in relation to sperm parameters and outcomes of assisted reproductive technologies","volume":"117","author":"Salas-Huetos","year":"2022","journal-title":"Fertil Steril"},{"issue":"11","key":"10.1016\/j.ejogrb.2026.114941_b0510","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1093\/aje\/kwaa073","article-title":"A prospective cohort study to evaluate the impact of diet, exercise, and lifestyle on fertility: design and baseline characteristics","volume":"189","author":"Mumford","year":"2020","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.ejogrb.2026.114941_b0515","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1346084","article-title":"Lifestyle and fertility-specific quality of life affect reproductive outcomes in couples undergoing in vitro fertilization","volume":"15","author":"Urata","year":"2024","journal-title":"Front Endocrinol"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0520","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2447815","article-title":"Failure of colonization following gut microbiota transfer exacerbates DSS-induced colitis","volume":"17","author":"Gustafson","year":"2025","journal-title":"Gut Microbes"},{"issue":"2","key":"10.1016\/j.ejogrb.2026.114941_b0525","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/1471-0528.15881","article-title":"The vaginal microbiome in uterine transplantation","volume":"127","author":"Jones","year":"2020","journal-title":"BJOG"},{"issue":"6","key":"10.1016\/j.ejogrb.2026.114941_b0530","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1016\/j.fertnstert.2016.07.1066","article-title":"How does closed system vitrification of human oocytes affect the clinical outcome? a prospective, observational, cohort, noninferiority trial in an oocyte donation program","volume":"106","author":"Papatheodorou","year":"2016","journal-title":"Fertil Steril"},{"issue":"10","key":"10.1016\/j.ejogrb.2026.114941_b0535","doi-asserted-by":"crossref","first-page":"2896","DOI":"10.1007\/s43032-023-01252-6","article-title":"Assisted reproductive techniques and risk of congenital heart diseases in children: a systematic review and meta-analysis","volume":"30","author":"Gullo","year":"2023","journal-title":"Reproductive sciences (Thousand Oaks, Calif)"},{"issue":"3","key":"10.1016\/j.ejogrb.2026.114941_b0540","article-title":"Artificial intelligence in in-vitro fertilization (IVF): a new era of precision and personalization in fertility treatments","volume":"54","author":"Olawade","year":"2025","journal-title":"J Gynecol Obstetr Hum Reproduct"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0545","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/s12978-024-01857-3","article-title":"Relationships between couple collaboration, well-being, and psychological health of infertile couples undergoing assisted reproductive treatment","volume":"21","author":"Reisi","year":"2024","journal-title":"Reprod Health"},{"issue":"1","key":"10.1016\/j.ejogrb.2026.114941_b0550","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/nop2.1062","article-title":"A qualitative study of the factors that help the coping of infertile women","volume":"9","author":"Halkola","year":"2022","journal-title":"Nurs Open"},{"issue":"1\u20132","key":"10.1016\/j.ejogrb.2026.114941_b0555","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s11010-020-03833-4","article-title":"Staphylococcal infections and infertility: mechanisms and management","volume":"474","author":"Dutta","year":"2020","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.ejogrb.2026.114941_b0560","first-page":"e3926","article-title":"Factors that affect career success of nurses who practice in assisted reproductive technology","volume":"31","author":"Li","year":"2023","journal-title":"Rev Lat Am Enfermagem"},{"issue":"5","key":"10.1016\/j.ejogrb.2026.114941_b0565","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1080\/14647273.2022.2163465","article-title":"Comparing infertility-related stress, coping, and quality of life among assisted reproductive technology and non-assisted reproductive technology treatments","volume":"26","author":"Swift","year":"2023","journal-title":"Hum Fertil (Camb)"}],"container-title":["European Journal of Obstetrics & Gynecology and Reproductive Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211526000072?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0301211526000072?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T11:20:30Z","timestamp":1779448830000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0301211526000072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":113,"alternative-id":["S0301211526000072"],"URL":"https:\/\/doi.org\/10.1016\/j.ejogrb.2026.114941","relation":{},"ISSN":["0301-2115"],"issn-type":[{"value":"0301-2115","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Microbiota and infertility: a translational review of mechanisms and clinical applications in assisted reproduction","name":"articletitle","label":"Article Title"},{"value":"European Journal of Obstetrics & Gynecology and Reproductive Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejogrb.2026.114941","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114941"}}