{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T19:05:08Z","timestamp":1774897508603,"version":"3.50.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Protistology"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.ejop.2023.126012","type":"journal-article","created":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T21:20:32Z","timestamp":1690579232000},"page":"126012","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Molecular characterization of methionine aminopeptidase1 from Eimeria tenella"],"prefix":"10.1016","volume":"90","author":[{"given":"Ke","family":"Xiao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haixia","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunhai","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyu","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"45","key":"10.1016\/j.ejop.2023.126012_b0005","doi-asserted-by":"crossref","first-page":"14741","DOI":"10.1021\/bi051691k","article-title":"Structural basis for the functional differences between type I and type II human methionine aminopeptidases","volume":"44","author":"Addlagatta","year":"2005","journal-title":"Biochemistry"},{"issue":"Pt 1","key":"10.1016\/j.ejop.2023.126012_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0031182002001828","article-title":"Properties, stage-dependent expression and localization of Plasmodium falciparum M1 family zinc-aminopeptidase","volume":"125","author":"Allary","year":"2002","journal-title":"Parasitology"},{"issue":"6","key":"10.1016\/j.ejop.2023.126012_b0015","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1002\/jcb.20493","article-title":"Methionine aminopeptidases type I and type II are essential to control cell proliferation","volume":"95","author":"Bernier","year":"2005","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.ejop.2023.126012_b0020","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/j.ijbiomac.2018.04.090","article-title":"Structural and functional highlights of methionine aminopeptidase 2 from Leishmania donovani","volume":"115","author":"Bhat","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"issue":"6473","key":"10.1016\/j.ejop.2023.126012_b0025","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1126\/science.aax4735","article-title":"A Kelch13-defined endocytosis pathway mediates artemisinin resistance in malaria parasites","volume":"367","author":"Birnbaum","year":"2020","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.ejop.2023.126012_b0030","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.pt.2013.10.003","article-title":"Securing poultry production from the ever-present Eimeria challenge","volume":"30","author":"Blake","year":"2014","journal-title":"Trends Parasitol."},{"issue":"7","key":"10.1016\/j.ejop.2023.126012_b0035","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0968-0004(98)01227-4","article-title":"N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families","volume":"23","author":"Bradshaw","year":"1998","journal-title":"Trends. Biochem. Sci."},{"issue":"1\u20132","key":"10.1016\/j.ejop.2023.126012_b0040","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0303-7207(95)03529-G","article-title":"Aminopeptidase-B in the rat testes: isolation, functional properties and cellular localization in the seminiferous tubules","volume":"110","author":"Cadel","year":"1995","journal-title":"Mol. Cell. Endocrinol."},{"issue":"7","key":"10.1016\/j.ejop.2023.126012_b0045","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.1128\/jb.171.7.4071-4072.1989","article-title":"Methionine aminopeptidase gene of Escherichia coli is essential for cell growth","volume":"171","author":"Chang","year":"1989","journal-title":"J. Bacteriol."},{"issue":"3","key":"10.1016\/j.ejop.2023.126012_b0050","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.ijpddr.2014.10.002","article-title":"Vaccination of chickens against coccidiosis ameliorates drug resistance in commercial poultry production","volume":"4","author":"Chapman","year":"2014","journal-title":"Int. J. Parasitol. Drugs Drug Resist."},{"key":"10.1016\/j.ejop.2023.126012_b0055","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/B978-0-12-407705-8.00002-1","article-title":"A selective review of advances in coccidiosis research","volume":"83","author":"Chapman","year":"2013","journal-title":"Adv. Parasitol."},{"issue":"39","key":"10.1016\/j.ejop.2023.126012_b0060","doi-asserted-by":"crossref","first-page":"14548","DOI":"10.1073\/pnas.0604101103","article-title":"Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity","volume":"103","author":"Chen","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"issue":"2","key":"10.1016\/j.ejop.2023.126012_b0065","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.chembiol.2009.01.006","article-title":"Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo","volume":"16","author":"Chen","year":"2009","journal-title":"Chem. Biol."},{"issue":"12","key":"10.1016\/j.ejop.2023.126012_b0070","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1007\/s00018-004-3466-8","article-title":"Protein N-terminal methionine excision","volume":"61","author":"Giglione","year":"2004","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.ejop.2023.126012_b0075","first-page":"138","article-title":"Experimental induction of drug-resistant strains of Eimeria tenella to Diclazuril and Maduramycin. Chinese","author":"Han","year":"2004","journal-title":"J. Vet. Sci."},{"key":"10.1016\/j.ejop.2023.126012_b0080","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.exppara.2015.04.002","article-title":"Molecular characterization and functional analysis of subunit 7 of eukaryotic initiation factor 3 from Eimeria tenella","volume":"154","author":"Han","year":"2015","journal-title":"Exp. Parasitol."},{"issue":"9","key":"10.1016\/j.ejop.2023.126012_b0085","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1002\/eji.1830230946","article-title":"A mouse aminopeptidase N is a marker for antigen-presenting cells and appears to be co-expressed with major histocompatibility complex class II molecules","volume":"23","author":"Hansen","year":"1993","journal-title":"Eur. J. Immunol."},{"issue":"6","key":"10.1016\/j.ejop.2023.126012_b0090","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1007\/s00436-022-07508-5","article-title":"Molecular characterization of glyceraldehyde-3-phosphate dehydrogenase from Eimeria tenella","volume":"121","author":"Huang","year":"2022","journal-title":"Parasitol. Res."},{"issue":"3","key":"10.1016\/j.ejop.2023.126012_b0095","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s00436-009-1437-6","article-title":"Model structure of the immunodominant surface antigen of Eimeria tenella identified as a target for sporozoite-neutralizing monoclonal antibody","volume":"105","author":"Jahn","year":"2009","journal-title":"Parasitol. Res."},{"issue":"1","key":"10.1016\/j.ejop.2023.126012_b0100","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.140175","article-title":"MHJ_0461 is a multifunctional leucine aminopeptidase on the surface of Mycoplasma hyopneumoniae","volume":"5","author":"Jarocki","year":"2015","journal-title":"Open Biol."},{"issue":"2","key":"10.1016\/j.ejop.2023.126012_b0105","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1007\/s00436-011-2568-0","article-title":"Identification and partial characterization of a serine protease inhibitor (serpin) of Eimeria tenella","volume":"110","author":"Jiang","year":"2012","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ejop.2023.126012_b0110","doi-asserted-by":"crossref","first-page":"200","DOI":"10.4172\/jpb.1000407","article-title":"Exploring Realm of Proteases of Leishmania donovani Genome and Gene Expression Analysis of Proteases under Apoptotic Condition","volume":"9","author":"Kumar","year":"2016","journal-title":"J. Proteomics Bioinform."},{"issue":"1","key":"10.1016\/j.ejop.2023.126012_b0115","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/s41598-017-00186-9","article-title":"Methionine aminopeptidase 2 is a key regulator of apoptotic like cell death in Leishmania donovani","volume":"7","author":"Kumar","year":"2017","journal-title":"Sci Rep"},{"issue":"26","key":"10.1016\/j.ejop.2023.126012_b0120","doi-asserted-by":"crossref","first-page":"12357","DOI":"10.1073\/pnas.92.26.12357","article-title":"Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases","volume":"92","author":"Li","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.ejop.2023.126012_b0125","first-page":"38","article-title":"Separation and purification of the second generation merozoites of Eimeria tenella","volume":"12","author":"Liu","year":"2006","journal-title":"Anim. Husb. Vet. Med."},{"issue":"10","key":"10.1016\/j.ejop.2023.126012_b0130","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1007\/s00436-019-06437-0","article-title":"Molecular characterization of surface antigen 10 of Eimeria tenella","volume":"118","author":"Liu","year":"2019","journal-title":"Parasitol. Res."},{"issue":"1\u20132","key":"10.1016\/j.ejop.2023.126012_b0135","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0167-4838(99)00271-X","article-title":"Structure and function of the methionine aminopeptidases","volume":"1477","author":"Lowther","year":"2000","journal-title":"Biochim. Biophys. Acta."},{"key":"10.1016\/j.ejop.2023.126012_b0140","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.3892\/ijo.2013.1860","article-title":"The expression of the CEACAM19 gene, a novel member of the CEA family, is associated with breast cancer progression","volume":"42","author":"Michaelidou","year":"2013","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.ejop.2023.126012_b0145","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.vetpar.2016.02.024","article-title":"Molecular and biochemical characterization of methionine aminopeptidase of Babesia bovis as a potent drug target","volume":"221","author":"Munkhjargal","year":"2016","journal-title":"Vet. Parasitol."},{"issue":"4","key":"10.1016\/j.ejop.2023.126012_b0150","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1007\/s00436-010-1956-1","article-title":"Molecular cloning and characterization of a gene encoding methionine aminopeptidase 2 of Schistosoma japonicum","volume":"107","author":"Peng","year":"2010","journal-title":"Parasitol. Res."},{"issue":"10\u201311","key":"10.1016\/j.ejop.2023.126012_b0155","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.ijpara.2006.04.006","article-title":"The heat shock protein 90 of Eimeria tenella is essential for invasion of host cell and schizont growth","volume":"36","author":"P\u00e9roval","year":"2006","journal-title":"Int. J. Parasitol."},{"issue":"3","key":"10.1016\/j.ejop.2023.126012_b0160","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/j.1365-2249.2008.03843.x","article-title":"Immunomodulatory activity of a methionine aminopeptidase-2 inhibitor on B cell differentiation","volume":"155","author":"Priest","year":"2009","journal-title":"Clin. Exp. Immunol."},{"issue":"6","key":"10.1016\/j.ejop.2023.126012_b0165","doi-asserted-by":"crossref","first-page":"e01422","DOI":"10.1128\/AAC.01422-19","article-title":"In Vitro and In Vivo Characterization of Potent Antileishmanial Methionine Aminopeptidase 1 Inhibitors","volume":"64","author":"Rodriguez","year":"2020","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ejop.2023.126012_b0170","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3389\/fvets.2020.00101","article-title":"Poultry Coccidiosis: Design and Interpretation of Vaccine Studies","volume":"7","author":"Soutter","year":"2020","journal-title":"Front. Vet. Sci."},{"issue":"2","key":"10.1016\/j.ejop.2023.126012_b0175","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1006\/meth.1997.0509","article-title":"Techniques for isolation and characterization of apical organelles from Eimeria tenella sporozoites","volume":"13","author":"Tomley","year":"1997","journal-title":"Methods"},{"issue":"1","key":"10.1016\/j.ejop.2023.126012_b0180","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s12864-015-1298-6","article-title":"RNA Seq analysis of the Eimeria tenella gametocyte transcriptome reveals clues about the molecular basis for sexual reproduction and oocyst biogenesis","volume":"16","author":"Walker","year":"2015","journal-title":"BMC Genomics"},{"issue":"3","key":"10.1016\/j.ejop.2023.126012_b0185","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1007\/s00436-020-07014-6","article-title":"Molecular characterization and functional analysis of Eimeria tenella citrate synthase","volume":"120","author":"Wang","year":"2021","journal-title":"Parasitol. Res."},{"issue":"2","key":"10.1016\/j.ejop.2023.126012_b0190","first-page":"47","article-title":"Experimental Development of an Eimeria Tenella Resistant Strain to Salinomycin","volume":"29","author":"Wang","year":"2021","journal-title":"Chinese J. Anim. Infectious Dis."},{"issue":"4","key":"10.1016\/j.ejop.2023.126012_b0195","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/jeu.12790","article-title":"Comparative Transcriptome Analyses of Drug-sensitive and Drug-resistant Strains of Eimeria tenella by RNA-sequencing","volume":"67","author":"Xie","year":"2020","journal-title":"J. Eukaryot. Microbiol."},{"issue":"5","key":"10.1016\/j.ejop.2023.126012_b0200","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1111\/jeu.12798","article-title":"Molecular characterization of serine\/threonine protein phosphatase of Eimeria tenella","volume":"67","author":"Yu","year":"2020","journal-title":"J. Eukaryot. Microbiol."},{"issue":"6\u20137","key":"10.1016\/j.ejop.2023.126012_b0205","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.ijpara.2020.03.004","article-title":"TgMAP1c is involved in apicoplast biogenesis in Toxoplasma gondii","volume":"50","author":"Zheng","year":"2020","journal-title":"Int. J. Parasitol."}],"container-title":["European Journal of Protistology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0932473923000573?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0932473923000573?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T15:03:38Z","timestamp":1760540618000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0932473923000573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":41,"alternative-id":["S0932473923000573"],"URL":"https:\/\/doi.org\/10.1016\/j.ejop.2023.126012","relation":{},"ISSN":["0932-4739"],"issn-type":[{"value":"0932-4739","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular characterization of methionine aminopeptidase1 from Eimeria tenella","name":"articletitle","label":"Article Title"},{"value":"European Journal of Protistology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejop.2023.126012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"126012"}}