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Twenty\u2010eight healthy subjects (range 22\u201344 years) performed a 90\u2010min standardized task of correcting a text on a word\u2010processor. Monetary reward was given according to productivity in order to induce time pressure. Pain intensity, general tension, and eye strain were reported on visual analogue scales before, during and after the computer session. Intramuscular trapezius blood fluxes were recorded by laser\u2010Doppler flowmetry (LDF) and analyzed as % of baseline level. Muscle activity was measured from the upper trapezius and forearm extensors by surface electromyography (EMG), analyzed as % of a maximal calibration contraction, %EMG<jats:sub>max<\/jats:sub>. Pain, tension, and eye strain increased considerably during the computer session with different time course for pain and tension. The LDF of the active side of trapezius was elevated for 30min followed by a falling trend. There was an initial short\u2010lasting increase in the inactive trapezius. The upper trapezius EMG was low (&lt;3 % of EMG<jats:sub>max<\/jats:sub>) but increased during the work, similar in both the active and passive side. There was a significant time and blood flux interaction effect on pain in the shoulders\/neck, but no association with EMG. In conclusion, considerable neck\/shoulder pain may develop in healthy pain\u2010free subjects during 90min of office\u2010work and seems to be related to the regulation of trapezius muscle blood flow.<\/jats:p>","DOI":"10.1016\/j.ejpain.2008.11.003","type":"journal-article","created":{"date-parts":[[2008,12,11]],"date-time":"2008-12-11T12:54:24Z","timestamp":1229000064000},"page":"843-852","source":"Crossref","is-referenced-by-count":33,"title":["Pain induced by a single simulated office\u2010work session: Time course and association with muscle blood flux and muscle activity"],"prefix":"10.1002","volume":"13","author":[{"given":"Vegard","family":"Str\u00f8m","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stein","family":"Knardahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan K.","family":"Stanghelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilie","family":"R\u00f8e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,1,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.504"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0274(200102)39:2<180::AID-AJIM1005>3.0.CO;2-#"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf029"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-4610.1999.3906417.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-003-0979-z"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01340.2003"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.10050"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-201x.2000.00713.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-006-0138-4"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(91)90026-W"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043764-199910000-00010"},{"key":"e_1_2_7_13_1","first-page":"1","volume-title":"Applied longitudinal analysis","author":"Fitzmaurice G.M.","year":"2004"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-006-0216-7"},{"key":"e_1_2_7_15_1","first-page":"34","article-title":"Physiological aspects of the \u201cdefence\u201d and \u201cdefeat\u201d reactions","volume":"640","author":"Folkow B.","year":"1997","journal-title":"Acta Physiol Scand Suppl"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2007.03.009"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00140138608967275"},{"key":"e_1_2_7_18_1","first-page":"141","volume-title":"Electromyographical kinesiology","author":"H\u00e4gg G.M.","year":"1991"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1997.211bf.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1042\/cs0860015"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.714"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(98)00067-4"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.364"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199909)36:1 <104::AID-AJIM37>3.0.CO;2-6"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/02678370210140117"},{"key":"e_1_2_7_26_1","first-page":"65","article-title":"Psychological and social factors at work: contribution to musculoskeletal disorders and disabilities","volume":"27","author":"Knardahl S.","year":"2005","journal-title":"Giorn Ital Med del Lavoro Ergon"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(99)00237-7"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(98)00144-4"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00634295"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00634296"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02425479"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0258(20000715)19:13<1793::AID-SIM482>3.0.CO;2-Q"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.10038"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01111.2005"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2006.11.004"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2005.10.001"},{"key":"e_1_2_7_37_1","unstructured":"L.Punnett U.BergqvistVisual display unit work and upper extremity musculoskeletal disorders. 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