{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:06:23Z","timestamp":1782878783764,"version":"3.54.5"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T00:00:00Z","timestamp":1663286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.ejpb.2022.09.004","type":"journal-article","created":{"date-parts":[[2022,9,10]],"date-time":"2022-09-10T02:19:30Z","timestamp":1662776370000},"page":"194-205","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Antifungal nanosuspensions with surfactants and silver for the treatment of onychomycosis"],"prefix":"10.1016","volume":"179","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9735-0303","authenticated-orcid":false,"given":"Hisham","family":"Al-Obaidi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ieva","family":"Petraityte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1419-9773","authenticated-orcid":false,"given":"Thomas","family":"Hibbard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mridul","family":"Majumder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachith","family":"Kalgudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Gulrez","family":"Zariwala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejpb.2022.09.004_b0005","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1128\/CMR.11.3.415","article-title":"Onychomycosis: pathogenesis, diagnosis, and management","volume":"11","author":"Elewski","year":"1998","journal-title":"Clin. Microbiol. Rev."},{"issue":"6","key":"10.1016\/j.ejpb.2022.09.004_b0010","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1177\/1203475417716362","article-title":"Onychomycosis in the 21st Century: An Update on Diagnosis, Epidemiology, and Treatment","volume":"21","author":"Gupta","year":"2017","journal-title":"J. Cutan Med. Surg."},{"key":"10.1016\/j.ejpb.2022.09.004_b0015","doi-asserted-by":"crossref","first-page":"50","DOI":"10.23736\/S0392-0488.18.06001-7","article-title":"Evidence for biofilms in onychomycosis","volume":"154","author":"Gupta","year":"2019","journal-title":"G Ital Dermatol. Venereol."},{"key":"10.1016\/j.ejpb.2022.09.004_b0020","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/5584_2016_6","article-title":"The extracellular matrix of fungal biofilms","volume":"931","author":"Mitchell","year":"2016","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.ejpb.2022.09.004_b0025","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.cmi.2014.10.024","article-title":"ESCMID\u2217 guideline for the diagnosis and treatment of biofilm infections 2014","volume":"21","author":"H\u00f8iby","year":"2015","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.ejpb.2022.09.004_b0030","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/myc.12706","article-title":"In vitro biofilms and antifungal susceptibility of dermatophyte and non-dermatophyte moulds involved in foot mycosis","volume":"61","author":"Toukabri","year":"2018","journal-title":"Mycoses"},{"key":"10.1016\/j.ejpb.2022.09.004_b0035","doi-asserted-by":"crossref","first-page":"350","DOI":"10.2174\/1381612822666161107162109","article-title":"Amorphous and crystalline particulates: challenges and perspectives in drug delivery","volume":"23","author":"Al-Obaidi","year":"2017","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.ejpb.2022.09.004_b0040","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1111\/jphp.12645","article-title":"Atypical effects of incorporated surfactants on stability and dissolution properties of amorphous polymeric dispersions","volume":"68","author":"Al-Obaidi","year":"2016","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.ejpb.2022.09.004_b0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2019.110540","article-title":"Griseofulvin solvate solid dispersions with synergistic effect against fungal biofilms","volume":"184","author":"Al-Obaidi","year":"2019","journal-title":"Colloids Surf B Biointerfaces"},{"key":"10.1016\/j.ejpb.2022.09.004_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jddst.2021.102606","article-title":"Evaluation of the impact of surfactants on miscibility of griseofulvin in spray dried amorphous solid dispersions","volume":"64","author":"Bhanderi","year":"2021","journal-title":"J. Drug Delivery Sci. Technol."},{"issue":"4","key":"10.1016\/j.ejpb.2022.09.004_b0055","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1205\/fbp06022","article-title":"Control of flow-generated biofilms with surfactants: evidence of resistance and recovery","volume":"84","author":"Sim\u00f5es","year":"2006","journal-title":"Food Bioprod. Process."},{"issue":"14","key":"10.1016\/j.ejpb.2022.09.004_b0060","doi-asserted-by":"crossref","first-page":"7715","DOI":"10.3390\/ijms22147715","article-title":"Biodirected Synthesis of Silver Nanoparticles Using Aqueous Honey Solutions and Evaluation of Their Antifungal Activity against Pathogenic Candida Spp","volume":"22","author":"Czernel","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ejpb.2022.09.004_b0065","doi-asserted-by":"crossref","first-page":"6333","DOI":"10.1016\/j.biomaterials.2009.07.065","article-title":"Antifungal activity of silver nanoparticles against Candida spp","volume":"30","author":"Panacek","year":"2009","journal-title":"Biomaterials"},{"key":"10.1016\/j.ejpb.2022.09.004_b0070","doi-asserted-by":"crossref","first-page":"e1800525","DOI":"10.1002\/cbdv.201800525","article-title":"Antimycotic Activity Potentiation of Allium sativum Extract and Silver Nanoparticles against Trichophyton rubrum","volume":"16","author":"Robles-Martinez","year":"2019","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.ejpb.2022.09.004_b0075","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1111\/jam.12652","article-title":"Synthesis, characterization and antifungal activity of chemically and fungal-produced silver nanoparticles against Trichophyton rubrum","volume":"117","author":"Pereira","year":"2014","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.ejpb.2022.09.004_b0080","doi-asserted-by":"crossref","first-page":"63","DOI":"10.14715\/cmb\/2017.63.11.12","article-title":"Antifungal activity of silver nanoparticles on Fluconazole resistant Dermatophytes identified by (GACA)4 and isolated from primary school children suffering from Tinea Capitis in Ismailia - Egypt","volume":"63","author":"Amin","year":"2017","journal-title":"Cell Mol. Biol. (Noisy-le-grand)"},{"issue":"3","key":"10.1016\/j.ejpb.2022.09.004_b0085","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0378-5173(94)90249-6","article-title":"Effect of counterions on the interactions in solid dispersions between polyethylene glycol, griseofulvin and alkali dodecyl sulphates","volume":"110","author":"Ald\u00e9n","year":"1994","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ejpb.2022.09.004_b0090","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ejpb.2018.04.006","article-title":"Fabrication of inhaled hybrid silver\/ciprofloxacin nanoparticles with synergetic effect against Pseudomonas aeruginosa","volume":"128","author":"Al-Obaidi","year":"2018","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"2","key":"10.1016\/j.ejpb.2022.09.004_b0095","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0378-5173(79)90051-6","article-title":"Crystal-structure analysis of the desolvation of the chloroform solvate of Griseofulvin","volume":"2","author":"Cheng","year":"1979","journal-title":"Int. J. Pharm."},{"issue":"5","key":"10.1016\/j.ejpb.2022.09.004_b0100","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/BF01161404","article-title":"Crystal-structure of Griseofulvin","volume":"12","author":"Puttaraja","year":"1982","journal-title":"J. Crystallogr. Spectrosc. Res."},{"key":"10.1016\/j.ejpb.2022.09.004_b0105","doi-asserted-by":"crossref","first-page":"3867","DOI":"10.1007\/s11434-012-5245-5","article-title":"Comparative crystal structure determination of griseofulvin: Powder X-ray diffraction versus single-crystal X-ray diffraction","volume":"57","author":"Pan","year":"2012","journal-title":"Chin. Sci. Bull."},{"key":"10.1016\/j.ejpb.2022.09.004_b0110","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1002\/jps.23583","article-title":"Prediction of drug-polymer miscibility through the use of solubility parameter based flory-huggins interaction parameter and the experimental validation: PEG as model polymer","volume":"102","author":"Thakral","year":"2013","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejpb.2022.09.004_b0115","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1021\/ja01864a025","article-title":"On a theory of the van der Waals adsorption of gases","volume":"62","author":"Brunauer","year":"1940","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.ejpb.2022.09.004_b0120","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1365-2133.2011.10303.x","article-title":"Validation of bovine hoof slices as a model for infected human toenails: in vitro ciclopirox transungual permeation","volume":"165","author":"Monti","year":"2011","journal-title":"Br. J. Dermatol."}],"container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641122002004?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641122002004?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T16:50:11Z","timestamp":1760547011000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939641122002004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":24,"alternative-id":["S0939641122002004"],"URL":"https:\/\/doi.org\/10.1016\/j.ejpb.2022.09.004","relation":{},"ISSN":["0939-6411"],"issn-type":[{"value":"0939-6411","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antifungal nanosuspensions with surfactants and silver for the treatment of onychomycosis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmaceutics and Biopharmaceutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejpb.2022.09.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}