{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T21:20:43Z","timestamp":1784755243294,"version":"3.55.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.ejpb.2023.01.024","type":"journal-article","created":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T02:10:20Z","timestamp":1675390220000},"page":"5-12","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Hydroquinone cream-based polymer microneedle roller for the combined treatment of large-area chloasma"],"prefix":"10.1016","volume":"185","author":[{"given":"Yu Ting","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu Ying","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui Xing","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo Zhi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin Dong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejpb.2023.01.024_b0005","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.ijwd.2017.11.003","volume":"4","author":"Jiang","year":"2018","journal-title":"International Journal of Women's Dermatology"},{"key":"10.1016\/j.ejpb.2023.01.024_b0010","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.yder.2011.01.041","volume":"2011","author":"Glick","year":"2011","journal-title":"Yearbook of Dermatology and Dermatologic Surgery"},{"key":"10.1016\/j.ejpb.2023.01.024_b0015","first-page":"123","article-title":"Clinical, Cosmetic and Investigational","volume":"5","author":"Seite","year":"2012","journal-title":"Dermatology"},{"key":"10.1016\/j.ejpb.2023.01.024_b0020","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1590\/abd1806-4841.20143063","volume":"89","author":"Handel","year":"2014","journal-title":"An Bras Dermatol"},{"key":"10.1016\/j.ejpb.2023.01.024_b0025","volume":"17","author":"Kwon","year":"2016","journal-title":"International Journal of Molecular Sciences"},{"key":"10.1016\/j.ejpb.2023.01.024_b0030","doi-asserted-by":"crossref","first-page":"13","DOI":"10.7554\/eLife.15104","volume":"5","author":"Natale","year":"2016","journal-title":"Elife"},{"key":"10.1016\/j.ejpb.2023.01.024_b0035","doi-asserted-by":"crossref","unstructured":"M.P. D'Elia, M.C. Brandao, B.R. de Andrade Ramos, M.G. da Silva, L.D. Miot, S.E. DosSantos, H.A. Miot, BMC Medical Genetics 18 (2017) 17 Doi: 10.1186\/s12881-017-0378-7.","DOI":"10.1186\/s12881-017-0378-7"},{"key":"10.1016\/j.ejpb.2023.01.024_b0040","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/j.1529-8019.2006.00085.x","volume":"19","author":"Ortonne","year":"2006","journal-title":"Dermatologic Therapy"},{"key":"10.1016\/j.ejpb.2023.01.024_b0045","first-page":"781","article-title":"Journal of European Academy of","volume":"20","author":"Nordlund","year":"2006","journal-title":"Dermatology and Venereology"},{"key":"10.1016\/j.ejpb.2023.01.024_b0050","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1473-2165.2005.40202.x","volume":"4","author":"Westerhof","year":"2005","journal-title":"Journal of Cosmetic Dermatology"},{"key":"10.1016\/j.ejpb.2023.01.024_b0055","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/pcmr.12684","volume":"31","author":"Passeron","year":"2018","journal-title":"Pigment Cell and Melanoma Research"},{"key":"10.1016\/j.ejpb.2023.01.024_b0060","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/j.1346-8138.2007.00341.x","volume":"34","author":"Chung","year":"2007","journal-title":"Journal of Dermatology"},{"key":"10.1016\/j.ejpb.2023.01.024_b0065","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1600-0781.2009.00425.x","author":"Moncada","year":"2009","journal-title":"Photodermatology, Photoimmunology and Photomedicine"},{"key":"10.1016\/j.ejpb.2023.01.024_b0070","doi-asserted-by":"crossref","unstructured":"B T \u00c1lvarez, I G. M Garza, J P C-C\u00e1zares, C F Ahumada, C O Ovalle, J N Solis, B Moncada, Am J Dermatopathol 33 (2011) 291-295 Doi: 10.1097\/DAD.0b013e3181ef2d45.","DOI":"10.1097\/DAD.0b013e3181ef2d45"},{"key":"10.1016\/j.ejpb.2023.01.024_b0075","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.jdermsci.2007.01.009","volume":"46","author":"Kim","year":"2007","journal-title":"Journal of Dermatological Science"},{"key":"10.1016\/j.ejpb.2023.01.024_b0080","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.ijpharm.2018.12.019","volume":"556","author":"Chen","year":"2019","journal-title":"Int J Pharm"},{"key":"10.1016\/j.ejpb.2023.01.024_b0085","first-page":"121","author":"Akmal","year":"2019","journal-title":"Eur J Pharm Biopharm 140"},{"key":"10.1016\/j.ejpb.2023.01.024_b0090","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.ejpb.2013.10.007","volume":"86","author":"Kaur","year":"2014","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.ejpb.2023.01.024_b0095","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1038\/nbt.1504","volume":"26","author":"Prausnitz","year":"2008","journal-title":"Nature Biotechnology"},{"key":"10.1016\/j.ejpb.2023.01.024_b0100","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3109\/1061186X.2012.741136","volume":"21","author":"Lee","year":"2013","journal-title":"Journal of Drug Targeting"},{"key":"10.1016\/j.ejpb.2023.01.024_b0105","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.ejps.2013.05.005","volume":"50","author":"Tuan-Mahmood","year":"2013","journal-title":"European Journal of Pharmaceutical Sciences"},{"key":"10.1016\/j.ejpb.2023.01.024_b0110","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.ejpb.2021.04.016","volume":"164","author":"Liang","year":"2021","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.ejpb.2023.01.024_b0115","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3109\/14764172.2012.748201","volume":"15","author":"Seo","year":"2013","journal-title":"Journal of Cosmetic and Laser Therapy"},{"key":"10.1016\/j.ejpb.2023.01.024_b0120","volume":"163","author":"Huang","year":"2022","journal-title":"European Polymer Journal"},{"key":"10.1016\/j.ejpb.2023.01.024_b0125","first-page":"87","author":"S","year":"2017","journal-title":"Journal of Controlled Release 261"},{"key":"10.1016\/j.ejpb.2023.01.024_b0130","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.lfs.2015.12.051","volume":"168","author":"Hirobe","year":"2017","journal-title":"Life Sciences"},{"key":"10.1016\/j.ejpb.2023.01.024_b0135","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1590\/abd1806-4841.20154748","volume":"90","author":"Lima Ede","year":"2015","journal-title":"An Bras Dermatol"},{"key":"10.1016\/j.ejpb.2023.01.024_b0140","doi-asserted-by":"crossref","first-page":"15408","DOI":"10.1039\/C6RA26759A","volume":"7","author":"Li","year":"2017","journal-title":"RSC Advances"},{"key":"10.1016\/j.ejpb.2023.01.024_b0145","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jiec.2022.07.008","volume":"114","author":"Liu","year":"2022","journal-title":"J Ind Eng Chem"},{"key":"10.1016\/j.ejpb.2023.01.024_b0150","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jiec.2020.04.019","volume":"88","author":"Zhang","year":"2020","journal-title":"J Ind Eng Chem"},{"key":"10.1016\/j.ejpb.2023.01.024_b0155","doi-asserted-by":"crossref","first-page":"e0229545","DOI":"10.1371\/journal.pone.0229545","volume":"15","author":"Ashrafi","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.ejpb.2023.01.024_b0160","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/lsm.23233","volume":"52","author":"Kislevitz","year":"2020","journal-title":"Lasers in Surgery and Medicine"}],"updated-by":[{"DOI":"10.1016\/j.ejpb.2025.114865","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000}}],"container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641123000309?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641123000309?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T16:49:39Z","timestamp":1760546979000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939641123000309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":32,"alternative-id":["S0939641123000309"],"URL":"https:\/\/doi.org\/10.1016\/j.ejpb.2023.01.024","relation":{},"ISSN":["0939-6411"],"issn-type":[{"value":"0939-6411","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hydroquinone cream-based polymer microneedle roller for the combined treatment of large-area chloasma","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmaceutics and Biopharmaceutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejpb.2023.01.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}