{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T08:43:10Z","timestamp":1762332190155,"version":"build-2065373602"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T00:00:00Z","timestamp":1750464000000},"content-version":"am","delay-in-days":324,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100014055","name":"USAMRAA","doi-asserted-by":"publisher","award":["W81XWH-19-1-0005"],"award-info":[{"award-number":["W81XWH-19-1-0005"]}],"id":[{"id":"10.13039\/100014055","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.ejpb.2024.114365","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T17:16:58Z","timestamp":1718212618000},"page":"114365","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Sustained release system from PLGA particles co-encapsulated with inactivated influenza virus with natural killer T cell agonist \u03b1-galactosylceramide"],"prefix":"10.1016","volume":"201","author":[{"given":"Yuhan","family":"Wen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-8509-7674","authenticated-orcid":false,"given":"Zachary","family":"Sparks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian","family":"Hawkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4069-0539","authenticated-orcid":false,"given":"John","family":"Lednicky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georges","family":"Abboud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0195-5610","authenticated-orcid":false,"given":"Corwin","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1920-2900","authenticated-orcid":false,"given":"Anuj","family":"Chauhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Driver","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejpb.2024.114365_b0005","unstructured":"Past Seasons Vaccine Effectiveness Estimates [Online], 2021, Available: https:\/\/www.cdc.gov\/flu\/vaccines-work\/past-seasons-estimates.html#."},{"issue":"2","key":"10.1016\/j.ejpb.2024.114365_b0010","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/s41577-020-00479-7","article-title":"A guide to vaccinology: from basic principles to new developments","volume":"21","author":"Pollard","year":"2021","journal-title":"Nat. Rev. Immunol."},{"issue":"19","key":"10.1016\/j.ejpb.2024.114365_b0015","doi-asserted-by":"crossref","first-page":"7914","DOI":"10.1073\/pnas.1104588108","article-title":"Vaccine adjuvants aluminum and monophosphoryl lipid A provide distinct signals to generate protective cytotoxic memory CD8 T cells","volume":"108","author":"MacLeod","year":"2011","journal-title":"PNAS"},{"issue":"12","key":"10.1016\/j.ejpb.2024.114365_b0020","doi-asserted-by":"crossref","first-page":"4490","DOI":"10.1002\/jps.23311","article-title":"AF03, An alternative squalene emulsion-based vaccine adjuvant prepared by a phase inversion temperature method","volume":"101","author":"Klucker","year":"2012","journal-title":"J. Pharm. Sci."},{"issue":"2","key":"10.1016\/j.ejpb.2024.114365_b0025","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.imlet.2008.11.006","article-title":"Influenza vaccines: the virosome concept","volume":"122","author":"Wilschut","year":"2009","journal-title":"Immunol. Lett."},{"issue":"6","key":"10.1016\/j.ejpb.2024.114365_b0030","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.vaccine.2008.11.046","article-title":"Incorporation of LpxL1, a detoxified lipopolysaccharide adjuvant, in influenza H5N1 virosomes increases vaccine immunogenicity","volume":"27","author":"De Vries","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.ejpb.2024.114365_b0035","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jconrel.2013.11.013","article-title":"Evaluation of monophosphoryl lipid A as adjuvant for pulmonary delivered influenza vaccine","volume":"174","author":"Patil","year":"2014","journal-title":"J. Control. Release"},{"issue":"2","key":"10.1016\/j.ejpb.2024.114365_b0040","doi-asserted-by":"crossref","first-page":"64","DOI":"10.2174\/156802608783378882","article-title":"Synthetic TLR4-active glycolipids as vaccine adjuvants and stand-alone immunotherapeutics","volume":"8","author":"Johnson","year":"2008","journal-title":"CTMC"},{"issue":"5","key":"10.1016\/j.ejpb.2024.114365_b0045","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1089\/vim.2015.0144","article-title":"Characterization of immune responses to an inactivated avian influenza virus vaccine adjuvanted with nanoparticles containing CpG ODN","volume":"29","author":"Singh","year":"2016","journal-title":"Viral Immunol."},{"key":"10.1016\/j.ejpb.2024.114365_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.coi.2022.102229","article-title":"Resolving adjuvant mode of action to enhance vaccine efficacy","volume":"77","author":"Turley","year":"2022","journal-title":"Curr. Opin. Immunol."},{"issue":"5","key":"10.1016\/j.ejpb.2024.114365_b0055","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.4049\/jimmunol.100.5.1139","article-title":"Lack of adjuvant effect of A1PO4 on purified influenza virus hemagglutinins in man","volume":"100","author":"Davenport","year":"1968","journal-title":"J. Immunol."},{"issue":"6","key":"10.1016\/j.ejpb.2024.114365_b0060","doi-asserted-by":"crossref","first-page":"e1011485","DOI":"10.1371\/journal.ppat.1011485","article-title":"Targeting the MR1-MAIT cell axis improves vaccine efficacy and affords protection against viral pathogens","volume":"19","author":"Rashu","year":"2023","journal-title":"PLoS Pathog."},{"issue":"1","key":"10.1016\/j.ejpb.2024.114365_b0065","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/s12985-020-01449-0","article-title":"Role of \u03b3\u03b4 T cells in controlling viral infections with a focus on influenza virus: implications for designing novel therapeutic approaches","volume":"17","author":"Sabbaghi","year":"2020","journal-title":"Virol. J."},{"key":"10.1016\/j.ejpb.2024.114365_b0070","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.02172","article-title":"Modulation of immune responses to influenza A virus vaccines by natural killer T cells","volume":"11","author":"Driver","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ejpb.2024.114365_b0075","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cellimm.2018.04.005","article-title":"Intranasal delivery of influenza antigen by nanoparticles, but not NKT-cell adjuvant differentially induces the expression of B-cell activation factors in mice and swine","volume":"329","author":"Renu","year":"2018","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.ejpb.2024.114365_b0080","doi-asserted-by":"crossref","unstructured":"Z. Moldoveanu et al., Immune responses to influenza virus in orally and systemically immunized mice, in: J. Mestecky, J.R. McGhee (Eds.), New Strategies for Oral Immunization, vol. 146, in Current Topics in Microbiology and Immunology, vol. 146, Springer Berlin Heidelberg, Berlin, Heidelberg, 1989, pp. 91\u201399, doi: 10.1007\/978-3-642-74529-4_10.","DOI":"10.1007\/978-3-642-74529-4_10"},{"issue":"1","key":"10.1016\/j.ejpb.2024.114365_b0085","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1093\/infdis\/167.1.84","article-title":"Oral immunization with influenza virus in biodegradable microspheres","volume":"167","author":"Moldoveanu","year":"1993","journal-title":"J. Infect. Dis."},{"issue":"2","key":"10.1016\/j.ejpb.2024.114365_b0090","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0168-3659(98)00161-8","article-title":"Biodegradable microparticles of influenza viral vaccine: comparison of the effects of routes of administration on the in vivo immune response in mice","volume":"58","author":"Chattaraj","year":"1999","journal-title":"J. Control. Release"},{"issue":"9\u201310","key":"10.1016\/j.ejpb.2024.114365_b0095","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/S0264-410X(98)00323-5","article-title":"Biodegradable microspheres containing influenza A vaccine: immune response in mice","volume":"17","author":"Hilbert","year":"1999","journal-title":"Vaccine"},{"issue":"9","key":"10.1016\/j.ejpb.2024.114365_b0100","first-page":"723","article-title":"Comparison of biodegradable nanoparticles and multiple emulsions (water-in-oil-in-water) containing influenza virus antigen on the in vivo immune response in rats","volume":"59","author":"Bozkir","year":"2004","journal-title":"Pharmazie"},{"issue":"11","key":"10.1016\/j.ejpb.2024.114365_b0105","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1016\/j.vaccine.2005.10.032","article-title":"Encapsulation of proteins and peptides into biodegradable poly(D, L-lactide-co-glycolide) microspheres prolongs and enhances antigen presentation by human dendritic cells","volume":"24","author":"Waeckerle-Men","year":"2006","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.ejpb.2024.114365_b0110","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.jconrel.2009.10.033","article-title":"Claudin 4-targeted protein incorporated into PLGA nanoparticles can mediate M cell targeted delivery","volume":"142","author":"Rajapaksa","year":"2010","journal-title":"J. Control. Release"},{"issue":"4","key":"10.1016\/j.ejpb.2024.114365_b0115","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.nano.2012.11.001","article-title":"Development of a nanoparticle-based influenza vaccine using the PRINT\u00ae technology","volume":"9","author":"Galloway","year":"2013","journal-title":"Nanomed.: Nanotechnol. Biol. Med."},{"issue":"40","key":"10.1016\/j.ejpb.2024.114365_b0120","doi-asserted-by":"crossref","first-page":"5373","DOI":"10.1016\/j.vaccine.2017.08.013","article-title":"A single dose and long lasting vaccine against pandemic influenza through the controlled release of a heterospecies tandem M2 sequence embedded within detoxified bacterial outer membrane vesicles","volume":"35","author":"Watkins","year":"2017","journal-title":"Vaccine"},{"key":"10.1016\/j.ejpb.2024.114365_b0125","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jconrel.2016.12.039","article-title":"Biodegradable nanoparticle delivery of inactivated swine influenza virus vaccine provides heterologous cell-mediated immune response in pigs","volume":"247","author":"Dhakal","year":"2017","journal-title":"J. Control. Release"},{"key":"10.1016\/j.ejpb.2024.114365_b0130","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jconrel.2015.08.019","article-title":"Cytotoxic T cell vaccination with PLGA microspheres interferes with influenza A virus replication in the lung and suppresses the infectious disease","volume":"216","author":"Herrmann","year":"2015","journal-title":"J. Control. Release"},{"issue":"7335","key":"10.1016\/j.ejpb.2024.114365_b0135","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/nature09737","article-title":"Programming the magnitude and persistence of antibody responses with innate immunity","volume":"470","author":"Kasturi","year":"2011","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.ejpb.2024.114365_b0140","article-title":"Adjuvantation of an influenza hemagglutinin antigen with TLR4 and NOD2 agonists encapsulated in Poly(D, L-lactide-co-glycolide) nanoparticles enhances immunogenicity and protection against lethal influenza virus infection in mice","volume":"8","author":"Tukhvatulin","year":"2020","journal-title":"Vaccines (Basel)"},{"issue":"1","key":"10.1016\/j.ejpb.2024.114365_b0145","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2015.1068493","article-title":"Co-delivery of PLGA encapsulated invariant NKT cell agonist with antigenic protein induce strong T cell-mediated antitumor immune responses","volume":"5","author":"D\u00f6len","year":"2016","journal-title":"Oncoimmunology"},{"issue":"1","key":"10.1016\/j.ejpb.2024.114365_b0150","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2020.1738813","article-title":"Nanovaccine administration route is critical to obtain pertinent iNKt cell help for robust anti-tumor T and B cell responses","volume":"9","author":"D\u00f6len","year":"2020","journal-title":"OncoImmunology"},{"issue":"1","key":"10.1016\/j.ejpb.2024.114365_b0155","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jconrel.2004.09.014","article-title":"Enhancement of T helper type 1 immune responses against hepatitis B virus core antigen by PLGA nanoparticle vaccine delivery","volume":"102","author":"Chong","year":"2005","journal-title":"J. Control. Release"},{"issue":"12","key":"10.1016\/j.ejpb.2024.114365_b0160","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1007\/s11095-004-7666-6","article-title":"Adsorption of a novel recombinant glycoprotein from HIV (Env gp120dV2 SF162) to anionic PLG microparticles retains the structural integrity of the protein, whereas encapsulation in PLG microparticles does not","volume":"21","author":"Singh","year":"2004","journal-title":"Pharm. Res."},{"issue":"3","key":"10.1016\/j.ejpb.2024.114365_b0165","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.jconrel.2005.10.010","article-title":"Encapsulation of the immune potentiators MPL and RC529 in PLG microparticles enhances their potency","volume":"110","author":"Kazzaz","year":"2006","journal-title":"J. Control. Release"},{"issue":"2","key":"10.1016\/j.ejpb.2024.114365_b0170","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.ejpb.2014.04.003","article-title":"Characterization of protein-adjuvant coencapsulation in microparticles for vaccine delivery","volume":"87","author":"Mathew","year":"2014","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.ejpb.2024.114365_b0175","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.ijms.2015.09.016","article-title":"Selective quantitation of the incorporation of the immunomodulator \u03b1-galactosylceramide in liposomes using LC\u2013MS\/MS","volume":"392","author":"Kaneko","year":"2015","journal-title":"Int. J. Mass Spectrom."},{"key":"10.1016\/j.ejpb.2024.114365_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.dci.2020.103843","article-title":"Unaltered influenza disease outcomes in swine prophylactically treated with \u03b1-galactosylceramide","volume":"114","author":"Gu","year":"2021","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.ejpb.2024.114365_b0185","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2022.999507","article-title":"Comparison of oseltamivir and \u03b1-galactosylceramide for reducing disease and transmission in pigs infected with 2009 H1N1 pandemic influenza virus","volume":"9","author":"Madrid","year":"2022","journal-title":"Front. Vet. Sci."},{"issue":"10","key":"10.1016\/j.ejpb.2024.114365_b0190","doi-asserted-by":"crossref","first-page":"3984","DOI":"10.1073\/pnas.0700191104","article-title":"Invariant NKT cells sustain specific B cell responses and memory","volume":"104","author":"Galli","year":"2007","journal-title":"PNAS"},{"issue":"1","key":"10.1016\/j.ejpb.2024.114365_b0195","doi-asserted-by":"crossref","DOI":"10.1038\/srep37999","article-title":"Rapid control of pandemic H1N1 influenza by targeting NKT-cells","volume":"6","author":"Artiaga","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ejpb.2024.114365_b0200","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1016\/j.nano.2018.05.020","article-title":"A33 antibody-functionalized exosomes for targeted delivery of doxorubicin against colorectal cancer","volume":"14","author":"Li","year":"2018","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"10.1016\/j.ejpb.2024.114365_b0205","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-34557-7","article-title":"Receptor-ligand interaction mediates targeting of endothelial colony forming cell-derived exosomes to the kidney after ischemic injury","volume":"8","author":"Vi\u00f1as","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ejpb.2024.114365_b0210","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aat0195","article-title":"Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy","author":"Gao","year":"2018","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.ejpb.2024.114365_b0215","doi-asserted-by":"crossref","first-page":"19514","DOI":"10.18632\/oncotarget.4004","article-title":"Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death","volume":"6","author":"Raimondo","year":"2015","journal-title":"Oncotarget"},{"issue":"1","key":"10.1016\/j.ejpb.2024.114365_b0220","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jconrel.2006.01.012","article-title":"Pharmaceutical and immunological evaluation of a single-dose hepatitis B vaccine using PLGA microspheres","volume":"112","author":"Feng","year":"2006","journal-title":"J. Control. Release"},{"issue":"11","key":"10.1016\/j.ejpb.2024.114365_b0225","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1128\/CVI.00374-14","article-title":"Influenza virus-specific neutralizing IgM antibodies persist for a lifetime","volume":"21","author":"Skountzou","year":"2014","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.ejpb.2024.114365_b0230","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ejps.2018.01.040","article-title":"Dual dye in-vivo imaging of differentially charged PLGA carriers reveals antigen-depot effect, leading to improved immune responses in preclinical models","volume":"117","author":"Riehl","year":"2018","journal-title":"Eur. J. Pharm. Sci."},{"issue":"2","key":"10.1016\/j.ejpb.2024.114365_b0235","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jconrel.2011.10.029","article-title":"Polyelectrolyte LbL microcapsules versus PLGA microparticles for immunization with a protein antigen","volume":"158","author":"De Temmerman","year":"2012","journal-title":"J. Control. Release"},{"issue":"9","key":"10.1016\/j.ejpb.2024.114365_b0240","doi-asserted-by":"crossref","first-page":"2572","DOI":"10.1172\/JCI24762","article-title":"Glycolipid antigen induces long-term natural killer T cell anergy in mice","volume":"115","author":"Parekh","year":"2005","journal-title":"J. Clin. Investig."},{"issue":"5","key":"10.1016\/j.ejpb.2024.114365_b0245","doi-asserted-by":"crossref","first-page":"3092","DOI":"10.4049\/jimmunol.175.5.3092","article-title":"NKT cell stimulation with glycolipid antigen in vivo: costimulation-dependent expansion, bim-dependent contraction, and hyporesponsiveness to further antigenic challenge","volume":"175","author":"Uldrich","year":"2005","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.ejpb.2024.114365_b0250","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1172\/JCI26297","article-title":"Activation or anergy: NKT cells are stunned by -galactosylceramide","volume":"115","author":"Sullivan","year":"2005","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.ejpb.2024.114365_b0255","unstructured":"C. Janeway (Ed.), Immunobiology: The Immune System in Health and Disease\u00a0; [animated CD-ROM inside], 5th ed., Garland Publ. [u.a.], New York, NY, 2001."}],"container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641124001917?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641124001917?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T08:38:33Z","timestamp":1762331913000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939641124001917"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":51,"alternative-id":["S0939641124001917"],"URL":"https:\/\/doi.org\/10.1016\/j.ejpb.2024.114365","relation":{},"ISSN":["0939-6411"],"issn-type":[{"type":"print","value":"0939-6411"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sustained release system from PLGA particles co-encapsulated with inactivated influenza virus with natural killer T cell agonist \u03b1-galactosylceramide","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmaceutics and Biopharmaceutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejpb.2024.114365","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"114365"}}