{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:15:48Z","timestamp":1790007348325,"version":"4.0.1"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T00:00:00Z","timestamp":1764806400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014786","name":"Northern Border University","doi-asserted-by":"publisher","award":["NBU-SAFIR-2025"],"award-info":[{"award-number":["NBU-SAFIR-2025"]}],"id":[{"id":"10.13039\/501100014786","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.ejpb.2025.114953","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T16:21:21Z","timestamp":1764951681000},"page":"114953","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Development of 3D-printed chitosan\/p-coumaric acid scaffolds for wound healing: antibacterial properties and drug release kinetics"],"prefix":"10.1016","volume":"219","author":[{"given":"Nouf D.","family":"Alshammari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2962-5387","authenticated-orcid":false,"given":"Prateek","family":"Uttreja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasha","family":"Elkanayati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leela Raghava","family":"Jaidev Chakka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9860-0976","authenticated-orcid":false,"given":"Sateesh Kumar","family":"Vemula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2049-4696","authenticated-orcid":false,"given":"Michael A.","family":"Repka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.ejpb.2025.114953_b0005","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.3390\/biomedicines11092457","article-title":"Chronic wound management: from gauze to homologous cellular matrix","volume":"11","author":"Popescu","year":"2023","journal-title":"Biomedicines"},{"issue":"11","key":"10.1016\/j.ejpb.2025.114953_b0010","doi-asserted-by":"crossref","first-page":"719","DOI":"10.4155\/tde-2019-0066","article-title":"Challenges and opportunities of pH in chronic wounds","volume":"10","author":"Wallace","year":"2019","journal-title":"Ther. Deliv."},{"issue":"1","key":"10.1016\/j.ejpb.2025.114953_b0015","doi-asserted-by":"crossref","first-page":"3431","DOI":"10.1038\/s41467-023-39129-6","article-title":"Scarless wound healing programmed by core-shell microneedles","volume":"14","author":"Zhang","year":"2023","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.ejpb.2025.114953_b0020","first-page":"159","article-title":"Chronic wounds: evaluation and management","volume":"101","author":"Bowers","year":"2020","journal-title":"Am. Fam. Physician"},{"issue":"1","key":"10.1016\/j.ejpb.2025.114953_b0025","doi-asserted-by":"crossref","first-page":"65","DOI":"10.7150\/thno.29766","article-title":"Engineering bioactive self-healing antibacterial exosomes hydrogel for promoting chronic diabetic wound healing and complete skin regeneration","volume":"9","author":"Wang","year":"2019","journal-title":"Theranostics"},{"issue":"2","key":"10.1016\/j.ejpb.2025.114953_b0030","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/bmjmilitary-2020-001509","article-title":"Novel micropore particle technology for spinal cord injury chronic wound healing: a new paradigm?","volume":"169","author":"O\u2019Sullivan","year":"2023","journal-title":"BMJ Mil. Health"},{"issue":"12","key":"10.1016\/j.ejpb.2025.114953_b0035","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1002\/jbm.b.34861","article-title":"Enhancing wound healing dressing development through interdisciplinary collaboration","volume":"109","author":"Hawthorne","year":"2021","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"issue":"12","key":"10.1016\/j.ejpb.2025.114953_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e22520","article-title":"The emerging progress on wound dressings and their application in clinic wound management","volume":"9","author":"Su","year":"2023","journal-title":"Heliyon"},{"issue":"4","key":"10.1016\/j.ejpb.2025.114953_b0045","article-title":"The trends in wound management: sensing, therapeutic treatment, and \u201ctheranostics.","volume":"8","author":"Yang","year":"2023","journal-title":"J. Sci.: Adv. Mater. Devices"},{"key":"10.1016\/j.ejpb.2025.114953_b0050","article-title":"Challenges in healing wound: role of complementary and alternative medicine","volume":"8","author":"Monika","year":"2021","journal-title":"Front. Nutr."},{"key":"10.1016\/j.ejpb.2025.114953_b0055","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.bjps.2025.01.036","article-title":"Benefits of negative pressure wound therapy in skin grafts: a systematic review and meta-analysis of randomised controlled trials","volume":"102","author":"Lee","year":"2025","journal-title":"J. Plast. Reconstr. Aesthet. Surg."},{"issue":"4","key":"10.1016\/j.ejpb.2025.114953_b0060","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1080\/15476278.2020.1844507","article-title":"An evaluation of wound healing efficacy of a film dressing made from polymer-integrated amnion membrane","volume":"16","author":"Wang","year":"2020","journal-title":"Organogenesis"},{"issue":"9","key":"10.1016\/j.ejpb.2025.114953_b0065","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.3390\/polym12092010","article-title":"Scaffolds for wound healing applications","volume":"12","author":"Negut","year":"2020","journal-title":"Polymers"},{"issue":"11","key":"10.1016\/j.ejpb.2025.114953_b0070","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.2217\/nnm-2017-0017","article-title":"Recent advances in electrospun nanofibers for wound healing","volume":"12","author":"Chen","year":"2017","journal-title":"Nanomed"},{"key":"10.1016\/j.ejpb.2025.114953_b0075","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.jconrel.2020.09.039","article-title":"Chronic wounds: current status, available strategies and emerging therapeutic solutions","volume":"328","author":"Las Heras","year":"2020","journal-title":"J. Controlled Release"},{"issue":"9","key":"10.1016\/j.ejpb.2025.114953_b0080","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/exd.13290","article-title":"Biomaterials: a potential pathway to healing chronic wounds?","volume":"26","author":"Pop","year":"2017","journal-title":"Exp. Dermatol."},{"issue":"10","key":"10.1016\/j.ejpb.2025.114953_b0085","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.3390\/pr12102100","article-title":"Challenges associated with the production of nanofibers","volume":"12","author":"Maduna","year":"2024","journal-title":"Processes"},{"key":"10.1016\/j.ejpb.2025.114953_b0090","doi-asserted-by":"crossref","unstructured":"Rohani Shirvan A, Hemmatinejad N, Bahrami SH, Bashari A. A comparison between solvent casting and electrospinning methods for the fabrication of neem extract-containing buccal films. J Ind Text. 2022 Jun;51(1_suppl):311S-335S.","DOI":"10.1177\/15280837211027785"},{"key":"10.1016\/j.ejpb.2025.114953_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.matchemphys.2022.126544","article-title":"Obtaining a freeze-dried biomaterial for skin regeneration: reinforcement of the microstructure through the use of crosslinkers and in vivo application","volume":"290","author":"Mello Zamudio","year":"2022","journal-title":"Mater. Chem. Phys."},{"issue":"122","key":"10.1016\/j.ejpb.2025.114953_b0100","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.actbio.2020.12.044","article-title":"3D and 4D printing in dentistry and maxillofacial surgery: printing techniques, materials, and applications","volume":"1","author":"Khorsandi","year":"2021","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.ejpb.2025.114953_b0105","doi-asserted-by":"crossref","DOI":"10.1088\/1758-5090\/8\/1\/014103","article-title":"Towards artificial tissue models: past, present, and future of 3D bioprinting","volume":"8","author":"Arslan-Yildiz","year":"2016","journal-title":"Biofabrication"},{"issue":"17","key":"10.1016\/j.ejpb.2025.114953_b0110","article-title":"Faster and protective wound healing mechanistic of para\u2010coumaric acid loaded liver ECM scaffold cross\u2010linked with acellular marine kelp","volume":"33","author":"Arin","year":"2023","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.ejpb.2025.114953_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2023.113280","article-title":"A bio-polymeric scaffold incorporated with p-Coumaric acid enhances diabetic wound healing by modulating MMP-9 and TGF-\u03b23 expression","volume":"225","author":"Selvakumar","year":"2023","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.ejpb.2025.114953_b0120","doi-asserted-by":"crossref","unstructured":"Acree WE, Barrera M, Abraham MH. Comment on \u201cMeasurement and Correlation of the Solubility of p -Coumaric Acid in Nine Pure and Water + Ethanol Mixed Solvents at Temperatures from 293.15 to 333.15 K.\u201d J Chem Eng Data. 2017 Jan 12;62(1):578\u201383.","DOI":"10.1021\/acs.jced.6b00807"},{"key":"10.1016\/j.ejpb.2025.114953_b0125","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.molstruc.2014.12.064","article-title":"Structural, thermal and quantum chemical studies of p-coumaric and caffeic acids","volume":"1085","author":"Kumar","year":"2015","journal-title":"J. Mol. Struct."},{"issue":"3","key":"10.1016\/j.ejpb.2025.114953_b0130","first-page":"411","article-title":"Chitin and chitosan: production and application of versatile biomedical nanomaterials","volume":"4","author":"Elieh-Ali-Komi","year":"2016","journal-title":"Int. J. Adv. Res."},{"issue":"7","key":"10.1016\/j.ejpb.2025.114953_b0135","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1080\/17425247.2019.1634051","article-title":"Hyaluronic acid and chitosan-based nanosystems: a new dressing generation for wound care","volume":"16","author":"Vigani","year":"2019","journal-title":"Expert Opin. Drug Deliv."},{"key":"10.1016\/j.ejpb.2025.114953_b0140","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.carbpol.2018.07.057","article-title":"3D-printed chitosan-based scaffolds: an in vitro study of human skin cell growth and an in-vivo wound healing evaluation in experimental diabetes in rats","volume":"199","author":"Intini","year":"2018","journal-title":"Carbohydr. Polym."},{"issue":"4","key":"10.1016\/j.ejpb.2025.114953_b0145","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.3390\/pharmaceutics15041313","article-title":"Chitosan: a potential biopolymer in drug delivery and biomedical applications","volume":"15","author":"Desai","year":"2023","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.ejpb.2025.114953_b0150","doi-asserted-by":"crossref","unstructured":"Osanloo M, Noori F, Varaa N, Tavassoli A, Goodarzi A, Moghaddam MT, et al. The wound healing effect of polycaprolactone-chitosan scaffold coated with a gel containing Zataria multiflora Boiss. volatile oil nanoemulsions. BMC Complement Med Ther. 2024 Jan 25;24(1):56.","DOI":"10.1186\/s12906-024-04352-1"},{"key":"10.1016\/j.ejpb.2025.114953_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2023.122709","article-title":"Disulfiram 3D printed film produced via hot-melt extrusion techniques as a potential anticervical cancer candidate","volume":"635","author":"Almotairy","year":"2023","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ejpb.2025.114953_b0160","article-title":"Mucoadhesive buccal films for treatment of xerostomia prepared by coupling HME and 3D printing technologies","volume":"75","author":"Elkanayati","year":"2022","journal-title":"J Drug Deliv Sci Technol."},{"key":"10.1016\/j.ejpb.2025.114953_b0165","doi-asserted-by":"crossref","unstructured":"Oh CM, Choi JY, Bae IA, Kim HT, Hong SS, Noah JK, et al. Identification of p-Coumaric Acid and Ethyl p-Coumarate as the Main Phenolic Components of Hemp (Cannabis sativa L.) Roots. Mol Basel Switz. 2022 Apr 27;27(9):2781.","DOI":"10.3390\/molecules27092781"},{"issue":"1","key":"10.1016\/j.ejpb.2025.114953_b0170","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.ejpb.2007.11.003","article-title":"Drug release mechanism of paclitaxel from a chitosan\u2013lipid implant system: effect of swelling, degradation and morphology","volume":"69","author":"Lim Soo","year":"2008","journal-title":"Eur. J. Pharm. Biopharm."},{"issue":"23","key":"10.1016\/j.ejpb.2025.114953_b0175","doi-asserted-by":"crossref","first-page":"5306","DOI":"10.3390\/polym14235306","article-title":"Production of 3D printed bi-layer and tri-layer sandwich scaffolds with polycaprolactone and poly (vinyl alcohol)-metformin towards diabetic wound healing","volume":"14","author":"Harmanci","year":"2022","journal-title":"Polymers"},{"issue":"1","key":"10.1016\/j.ejpb.2025.114953_b0180","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1208\/s12249-024-03004-4","article-title":"Formulation, development, and characterization of amb-based subcutaneous implants using PCL and PLGA via hot-melt extrusion","volume":"26","author":"Chitnis","year":"2024","journal-title":"AAPS PharmSciTech"},{"issue":"1","key":"10.1016\/j.ejpb.2025.114953_b0185","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00289-007-0846-x","article-title":"Properties of hydrophilic chitosan network membranes by introducing binary crosslink agents","volume":"60","author":"Tsai","year":"2008","journal-title":"Polym. Bull."},{"key":"10.1016\/j.ejpb.2025.114953_b0190","article-title":"Colon-targeted 3D-printed mesalamine tablets: core-shell design and in vitro\/ex-vivo evaluation","volume":"95","author":"Alshammari","year":"2024","journal-title":"J Drug Deliv Sci Technol."},{"key":"10.1016\/j.ejpb.2025.114953_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.matdes.2022.110394","article-title":"3D-printed polycaprolactone-chitosan based drug delivery implants for personalized administration","volume":"214","author":"Yang","year":"2022","journal-title":"Mater. Des."},{"issue":"11","key":"10.1016\/j.ejpb.2025.114953_b0200","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1002\/mabi.200350034","article-title":"Hydrogen\u2010bonding interaction and crystalline morphology in the binary blends of poly(\u03b5 \u2010caprolactone) and polyphenol catechin","volume":"3","author":"Zhu","year":"2003","journal-title":"Macromol. Biosci."},{"key":"10.1016\/j.ejpb.2025.114953_b0205","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/j.carbpol.2013.09.096","article-title":"Comprehensive characterization of chitosan\/PEO\/levan ternary blend films","volume":"102","author":"Bostan","year":"2014","journal-title":"Carbohydr. Polym."},{"issue":"1","key":"10.1016\/j.ejpb.2025.114953_b0210","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jconrel.2004.06.008","article-title":"Characterization of chitosan acetate as a binder for sustained release tablets","volume":"99","author":"Nunthanid","year":"2004","journal-title":"J. Controlled Release"},{"issue":"12","key":"10.1016\/j.ejpb.2025.114953_b0215","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1007\/s11051-020-05096-y","article-title":"Development and evaluation of polycaprolactone based docetaxel nanoparticle formulation for targeted breast cancer therapy","volume":"22","author":"Kolluru","year":"2020","journal-title":"J Nanoparticle Res."},{"issue":"3\u20134","key":"10.1016\/j.ejpb.2025.114953_b0220","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s10847-021-01121-2","article-title":"Formulation and modification of physicochemical parameters of p-Coumaric acid by cyclodextrin nanosponges","volume":"102","author":"Kumar","year":"2022","journal-title":"J. Incl. Phenom. Macrocycl. Chem."},{"issue":"4","key":"10.1016\/j.ejpb.2025.114953_b0225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0214956","article-title":"Low molecular weight \u03b5-caprolactone-p-coumaric acid copolymers as potential biomaterials for skin regeneration applications","volume":"14","author":"Contardi","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.ejpb.2025.114953_b0230","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.polymdegradstab.2014.12.006","article-title":"Advanced physico-chemical characterization of chitosan by means of TGA coupled on-line with FTIR and GCMS: thermal degradation and water adsorption capacity","volume":"112","author":"Corazzari","year":"2015","journal-title":"Polym. Degrad. Stab."},{"key":"10.1016\/j.ejpb.2025.114953_b0235","article-title":"Multilevel categoric factorial design for optimization of raloxifene hydrochloride solid dispersion in PVP K30 by hot-melt extrusion technology","volume":"92","author":"Elkanayati","year":"2024","journal-title":"J Drug Deliv Sci Technol."},{"key":"10.1016\/j.ejpb.2025.114953_b0240","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.foodchem.2018.01.091","article-title":"Combined spectroscopic, molecular docking and quantum mechanics study of \u03b2-casein and p-coumaric acid interactions following thermal treatment","volume":"252","author":"Kaur","year":"2018","journal-title":"Food Chem."},{"key":"10.1016\/j.ejpb.2025.114953_b0245","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.foodhyd.2019.02.044","article-title":"Lipophilization and molecular encapsulation of p-coumaric acid by amylose inclusion complex","volume":"93","author":"Wang","year":"2019","journal-title":"Food Hydrocoll."},{"key":"10.1016\/j.ejpb.2025.114953_b0250","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.ijbiomac.2015.01.063","article-title":"Characterization of polycaprolactone\/collagen fibrous scaffolds by electrospinning and their bioactivity","volume":"76","author":"Zhang","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"issue":"7","key":"10.1016\/j.ejpb.2025.114953_b0255","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1080\/15685551.2014.907621","article-title":"Fabrication and characterization of chitosan\u2013gelatin\/nanohydroxyapatite\u2013polyaniline composite with potential application in tissue engineering scaffolds","volume":"17","author":"Farshi Azhar","year":"2014","journal-title":"Des. Monomers Polym."},{"issue":"3","key":"10.1016\/j.ejpb.2025.114953_b0260","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.carbpol.2009.11.050","article-title":"Preparation and characterization of chitosan\u2013gelatin\/nanohydroxyapatite composite scaffolds for tissue engineering applications","volume":"80","author":"Peter","year":"2010","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ejpb.2025.114953_b0265","article-title":"Effect of pH modifiers on the solubility, dissolution rate, and stability of telmisartan solid dispersions produced by hot-melt extrusion technology","volume":"65","author":"Almotairy","year":"2021","journal-title":"J Drug Deliv Sci Technol."},{"key":"10.1016\/j.ejpb.2025.114953_b0270","article-title":"Formulation development of curcumin-piperine solid dispersion via hot-melt extrusion","volume":"76","author":"Althobaiti","year":"2022","journal-title":"J Drug Deliv Sci Technol."},{"issue":"13","key":"10.1016\/j.ejpb.2025.114953_b0275","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.3390\/polym16131934","article-title":"Electrospun ibuprofen-loaded blend PCL\/PEO fibers for topical drug delivery applications","volume":"16","author":"Bani Mustafa","year":"2024","journal-title":"Polymers"},{"issue":"1","key":"10.1016\/j.ejpb.2025.114953_b0280","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.2042-7158.1980.tb12970.x","article-title":"Zero order drug delivery from double-layered porous films: release rate profiles from ethyl cellulose, hydroxypropyl cellulose and polyethylene glycol mixtures","volume":"32","author":"Donbrow","year":"2011","journal-title":"J. Pharm. Pharmacol."},{"issue":"12","key":"10.1016\/j.ejpb.2025.114953_b0285","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1002\/jps.2600521210","article-title":"Mechanism of sustained\u2010action medication. Theoretical analysis of rate of release of solid drugs dispersed in solid matrices","volume":"52","author":"Higuchi","year":"1963","journal-title":"J. Pharm. Sci."},{"issue":"6","key":"10.1016\/j.ejpb.2025.114953_b0290","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1080\/03639040601179954","article-title":"Drug release kinetics from tablet matrices based upon ethylcellulose ether-derivatives: a comparison between different formulations","volume":"33","author":"Khan","year":"2007","journal-title":"Drug Dev. Ind. Pharm."},{"issue":"1","key":"10.1016\/j.ejpb.2025.114953_b0295","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/0378-5173(83)90064-9","article-title":"Mechanisms of solute release from porous hydrophilic polymers","volume":"15","author":"Korsmeyer","year":"1983","journal-title":"Int. J. Pharm."},{"issue":"4","key":"10.1016\/j.ejpb.2025.114953_b0300","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1517\/17425241003602259","article-title":"Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems","volume":"7","author":"Fu","year":"2010","journal-title":"Expert Opin. Drug Deliv."},{"issue":"5","key":"10.1016\/j.ejpb.2025.114953_b0305","doi-asserted-by":"crossref","first-page":"545","DOI":"10.3390\/ph17050545","article-title":"Antibacterial, anti-biofilm, and anti-inflammatory properties of gelatin\u2013chitosan\u2013moringa-biopolymer-based wound dressings towards staphylococcus aureus and escherichia coli","volume":"17","author":"Bessalah","year":"2024","journal-title":"Pharmaceuticals"},{"issue":"3","key":"10.1016\/j.ejpb.2025.114953_b0310","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/jbm.a.30808","article-title":"Antimicrobial effect of silver\u2010doped phosphate\u2010based glasses","volume":"79A","author":"Ahmed","year":"2006","journal-title":"J. Biomed. Mater. Res. A"},{"key":"10.1016\/j.ejpb.2025.114953_b0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.125087","article-title":"Preparation and characterization of antibacterial, antioxidant, and biocompatible p-coumaric acid modified quaternized chitosan nanoparticles","volume":"242","author":"Li","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ejpb.2025.114953_b0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2021.117930","article-title":"Characterization of polyvinyl alcohol\/starch composite films incorporated with p-coumaric acid modified chitosan and chitosan nanoparticles: a comparative study","volume":"262","author":"Lee","year":"2021","journal-title":"Carbohydr. Polym."},{"issue":"3","key":"10.1016\/j.ejpb.2025.114953_b0325","doi-asserted-by":"crossref","first-page":"455","DOI":"10.3390\/molecules30030455","article-title":"Exploring the potential of chitosan\u2013phytochemical composites in preventing the contamination of antibiotic-resistant bacteria on food surfaces: a review","volume":"30","author":"Doan","year":"2025","journal-title":"Molecules"}],"container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641125003315?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641125003315?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T06:39:14Z","timestamp":1773902354000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939641125003315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":65,"alternative-id":["S0939641125003315"],"URL":"https:\/\/doi.org\/10.1016\/j.ejpb.2025.114953","relation":{},"ISSN":["0939-6411"],"issn-type":[{"value":"0939-6411","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of 3D-printed chitosan\/p-coumaric acid scaffolds for wound healing: antibacterial properties and drug release kinetics","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmaceutics and Biopharmaceutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejpb.2025.114953","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"114953"}}