{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T09:07:05Z","timestamp":1793869625742,"version":"4.6.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFD1700500"],"award-info":[{"award-number":["2024YFD1700500"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","award":["231107541242397"],"award-info":[{"award-number":["231107541242397"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","award":["231107541235424"],"award-info":[{"award-number":["231107541235424"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.ejpb.2026.115046","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T09:39:52Z","timestamp":1773049192000},"page":"115046","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["One-step synthesized NIR-responsive polydopamine nanoparticles for synergistic nitric oxide chemotherapy and photothermal therapy against multidrug-resistant bacteria"],"prefix":"10.1016","volume":"223","author":[{"given":"Jiale","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuru","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitao","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuanmin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5641-3539","authenticated-orcid":false,"given":"Yanrong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejpb.2026.115046_b0005","doi-asserted-by":"crossref","first-page":"6278","DOI":"10.1039\/D3NA00530E","article-title":"Recent advances in nanoantibiotics against multidrug-resistant bacteria","volume":"5","author":"Li","year":"2023","journal-title":"Nanoscale Adv."},{"key":"10.1016\/j.ejpb.2026.115046_b0010","article-title":"Nitric oxide released injectable hydrogel combined with synergistic photothermal therapy for antibacterial and accelerated wound healing","volume":"20","author":"Liu","year":"2020","journal-title":"Appl. Mater. Today"},{"key":"10.1016\/j.ejpb.2026.115046_b0015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12274-021-3417-4","article-title":"Nanomaterial-based strategies in antimicrobial applications: progress and perspectives","volume":"14","author":"Zhao","year":"2021","journal-title":"Nano Res."},{"key":"10.1016\/j.ejpb.2026.115046_b0020","doi-asserted-by":"crossref","first-page":"7909","DOI":"10.3390\/ijms23147909","article-title":"Antitumor applications of photothermal agents and photothermal synergistic therapies","volume":"23","author":"Li","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ejpb.2026.115046_b0025","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.niox.2020.10.003","article-title":"Chitosan chemically modified to deliver nitric oxide with high antibacterial activity","volume":"106","author":"Pelegrino","year":"2021","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.ejpb.2026.115046_b0030","first-page":"522","article-title":"Nanoparticles modified by polydopamine: working as \u201cdrug\u201d carriers","volume":"5","author":"Jin","year":"2020","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.ejpb.2026.115046_b0035","article-title":"Polydopamine-based nanostructures: a new generation of versatile, multi-tasking, and smart theranostic tools","volume":"55","author":"Matteo","year":"2024","journal-title":"Nano Today"},{"key":"10.1016\/j.ejpb.2026.115046_b0040","article-title":"Active food packaging based on chitosan-gelatin nanocomposites functionalized with bioactive nanoparticles: fabrication, properties, and application in seafood preservation","volume":"227","author":"Hui","year":"2026","journal-title":"Food Res. Int."},{"key":"10.1016\/j.ejpb.2026.115046_b0045","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.actbio.2022.02.029","article-title":"Near-infrared laser-controlled nitric oxide-releasing gold nanostar\/hollow polydopamine Janus nanoparticles for synergistic elimination of methicillin-resistant Staphylococcus aureus and wound healing","volume":"143","author":"Liang","year":"2022","journal-title":"Acta Biomater."},{"key":"10.1016\/j.ejpb.2026.115046_b0050","doi-asserted-by":"crossref","first-page":"e2101476","DOI":"10.1002\/adhm.202101476","article-title":"Polydopamine nanosheets doped injectable hydrogel with nitric oxide release and photothermal effects for bacterial ablation and wound healing","volume":"10","author":"Liu","year":"2021","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.ejpb.2026.115046_b0055","doi-asserted-by":"crossref","first-page":"11499","DOI":"10.2147\/IJN.S486640","article-title":"Controlled nitric oxide-releasing nanovehicles for enhanced infected wound healing: a study on PDA@BNN6 encapsulated in GelMA hydrogel","volume":"2024","author":"Yang","year":"2024","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.ejpb.2026.115046_b0060","doi-asserted-by":"crossref","first-page":"e2300247","DOI":"10.1002\/adhm.202300247","article-title":"Bacteria-targeted combined with photothermal\/NO nanoparticles for the treatment and diagnosis of MRSA infection in vivo","volume":"12","author":"Lv","year":"2023","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.ejpb.2026.115046_b0065","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1021\/acsestwater.1c00065","article-title":"Determination of nitrate in natural waters by vanadium reduction and the griess assay: reassessment and optimization","volume":"1","author":"Pai","year":"2021","journal-title":"ACS EST Water."},{"key":"10.1016\/j.ejpb.2026.115046_b0070","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.jcis.2025.01.007","article-title":"Multifunctional metal\u2013organic frameworks with photothermal-triggered nitric oxide release for gas\/photothermal synergistic cancer therapy","volume":"684","author":"Luo","year":"2025","journal-title":"J. Colloid Interf. Sci."},{"key":"10.1016\/j.ejpb.2026.115046_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.123445","article-title":"Multifunctional chitosan\/alginate hydrogel incorporated with bioactive glass nanocomposites enabling photothermal and nitric oxide release activities for bacteria-infected wound healing","volume":"232","author":"Zhang","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ejpb.2026.115046_b0080","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.actbio.2022.05.006","article-title":"An injectable and biodegradable hydrogel incorporated with photoregulated NO generators to heal MRSA-infected wounds","volume":"146","author":"Lv","year":"2022","journal-title":"Acta Biomater."},{"key":"10.1016\/j.ejpb.2026.115046_b0085","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202303095","article-title":"An injectable self\u2010crosslinked wholly supramolecular polyzwitterionic hydrogel for regulating microenvironment to boost infected diabetic wound healing","volume":"33","author":"Pang","year":"2023","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.ejpb.2026.115046_b0090","article-title":"Mild NIR controlled NO-Releasing adenine-based composite hydrogel with excellent Antimicrobial, wound adaptiveness and angiogenic capabilities for rapid bacterial-infected wounds healing","volume":"238","author":"He","year":"2024","journal-title":"Mater Design."},{"key":"10.1016\/j.ejpb.2026.115046_b0095","doi-asserted-by":"crossref","DOI":"10.3389\/fchem.2022.1111701","article-title":"Polydopamine-based nanospheres as nanoplatforms to kill Staphylococcus aureus and to promote wound healing by photothermal therapy","volume":"10","author":"Hou","year":"2022","journal-title":"Front. Chem."},{"key":"10.1016\/j.ejpb.2026.115046_b0100","article-title":"Polydopamine nanocomposite-based aptasensor for rapid detection and effective killing of Staphylococcus aureus","volume":"68","author":"Zhang","year":"2025","journal-title":"Food Biosci."},{"key":"10.1016\/j.ejpb.2026.115046_b0105","article-title":"Strategically staged tumor ablation and inflammation suppression using shell-core nanoparticles to eradicate bladder tumors and prevent recurrence","volume":"34","author":"Xu","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.ejpb.2026.115046_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.130225","article-title":"Nitric oxide-releasing multifunctional catechol-modified chitosan\/oxidized dextran hydrogel with antibacterial, antioxidant, and pro-angiogenic properties for MRSA-infected diabetic wound healing","volume":"263","author":"Liu","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ejpb.2026.115046_b0115","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3390\/polym13010090","article-title":"Thermal behaviour of common thermoresponsive polymers in phosphate buffer and in its salt solutions","volume":"13","author":"Otulakowski","year":"2020","journal-title":"Polymers"},{"key":"10.1016\/j.ejpb.2026.115046_b0120","doi-asserted-by":"crossref","DOI":"10.1002\/admi.202201442","article-title":"Characterization and biomedical application opportunities of the nanoparticle's protein corona","volume":"9","author":"Li","year":"2022","journal-title":"Adv. Mater. Interfaces"},{"key":"10.1016\/j.ejpb.2026.115046_b0125","doi-asserted-by":"crossref","first-page":"18198","DOI":"10.1039\/D1RA02116H","article-title":"Probing protein dissociation from gold nanoparticles and the influence of temperature from the protein corona formation mechanism","volume":"11","author":"Li","year":"2021","journal-title":"RSC Adv."},{"key":"10.1016\/j.ejpb.2026.115046_b0130","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3390\/jfb16030091","article-title":"Nanoparticle-enhanced collagen hydrogels for chronic wound management","volume":"16","author":"Alexandra","year":"2025","journal-title":"J Funct Biomater."},{"key":"10.1016\/j.ejpb.2026.115046_b0135","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.3390\/cells14201637","article-title":"Biological nanoparticles for enhancing chronic wound regeneration","volume":"14","author":"Daniil","year":"2025","journal-title":"Cells"}],"container-title":["European Journal of Pharmaceutics and Biopharmaceutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641126000676?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0939641126000676?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T12:25:57Z","timestamp":1782822357000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0939641126000676"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":27,"alternative-id":["S0939641126000676"],"URL":"https:\/\/doi.org\/10.1016\/j.ejpb.2026.115046","relation":{},"ISSN":["0939-6411"],"issn-type":[{"value":"0939-6411","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"One-step synthesized NIR-responsive polydopamine nanoparticles for synergistic nitric oxide chemotherapy and photothermal therapy against multidrug-resistant bacteria","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmaceutics and Biopharmaceutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejpb.2026.115046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"115046"}}