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A."},{"key":"10.1016\/j.ejphar.2003.08.101_BIB75","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0006-8993(91)90970-7","article-title":"Neuronal localization of cannabinoid receptors in the basal ganglia of the rat","volume":"547","author":"Herkenham","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.ejphar.2003.08.101_BIB76","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1523\/JNEUROSCI.11-02-00563.1991","article-title":"Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study","volume":"11","author":"Herkenham","year":"1991","journal-title":"J. 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Biol. Chem."},{"key":"10.1016\/j.ejphar.2003.08.101_BIB80","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1126\/science.1167428","article-title":"Morphine-dependent rats: blockade of precipitated abstinence by tetrahydrocannabinol","volume":"187","author":"Hine","year":"1975","journal-title":"Science"},{"key":"10.1016\/j.ejphar.2003.08.101_BIB81","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1152\/jn.2001.85.1.72","article-title":"Direct actions of cannabinoids on synaptic transmission in the nucleus accumbens: a comparison with opioids","volume":"85","author":"Hoffman","year":"2001","journal-title":"J. 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A."},{"key":"10.1016\/j.ejphar.2003.08.101_BIB86","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1038\/sj.bjp.0704379","article-title":"Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats","volume":"134","author":"Jamshidi","year":"2001","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2003.08.101_BIB87","doi-asserted-by":"crossref","DOI":"10.1016\/S0306-4522(03)00070-8","article-title":"Neuroanatomical relationship between type 1 cannabinoid receptors and dopaminergic systems in the rat basal ganglia","author":"Julian","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.ejphar.2003.08.101_BIB88","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/nm803","article-title":"Modulation of anxiety through blockade of anandamide hydrolysis","volume":"9","author":"Kathuria","year":"2003","journal-title":"Nat. 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Neurosci."},{"key":"10.1016\/j.ejphar.2003.08.101_BIB92","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0896-6273(01)00246-X","article-title":"Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells","volume":"29","author":"Kreitzer","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.ejphar.2003.08.101_BIB93","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S0028-3908(01)00039-9","article-title":"Chronic treatment with Delta(9)-tetrahydrocannabinol enhances the locomotor response to amphetamine and heroin. 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