{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:17:01Z","timestamp":1761707821541,"version":"3.32.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2005,9]]},"DOI":"10.1016\/j.ejphar.2005.06.044","type":"journal-article","created":{"date-parts":[[2005,9,25]],"date-time":"2005-09-25T11:13:42Z","timestamp":1127646822000},"page":"1-11","source":"Crossref","is-referenced-by-count":20,"title":["Albumin prevents mitochondrial depolarization and apoptosis elicited by endoplasmic reticulum calcium depletion of neuroblastoma cells"],"prefix":"10.1016","volume":"520","author":[{"given":"Sonia","family":"Gallego-Sand\u00edn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Novalbos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ar\u00e1nzazu","family":"Rosado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda F.","family":"Cano-Abad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esperanza","family":"Arias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Abad-Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio G.","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2005.06.044_bib1","doi-asserted-by":"crossref","first-page":"22368","DOI":"10.1074\/jbc.M011688200","article-title":"Hypoxia induces the activation of phosphatidylinositol 3-kinase\/Akt cell survival pathway in PC12 cells. Protective role in apoptosis","volume":"276","author":"\u00c1lvarez-Tejado","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib2","series-title":"Plasma Proteins","first-page":"43","article-title":"Serum albumin","author":"Andersson","year":"1979"},{"key":"10.1016\/j.ejphar.2005.06.044_bib3","doi-asserted-by":"crossref","first-page":"44735","DOI":"10.1074\/jbc.M302673200","article-title":"Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes","volume":"278","author":"Aon","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib4","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0028-3908(03)00317-4","article-title":"Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors","volume":"46","author":"Arias","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ejphar.2005.06.044_bib5","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1006\/bbrc.2001.5042","article-title":"An analog of the human albumin N-terminus (Asp-Ala-His-Lys) prevents formation of copper-induced reactive oxygen species","volume":"284","author":"Bar-Or","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ejphar.2005.06.044_bib6","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1161\/01.STR.32.2.553","article-title":"Human albumin therapy of acute ischemic stroke. Marked neuroprotective efficacy at moderate doses and with a broad therapeutic window","volume":"32","author":"Belayev","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.ejphar.2005.06.044_bib7","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/BF02110643","article-title":"The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal","volume":"28","author":"Bernardi","year":"1996","journal-title":"J. Bioenerg. Biomembranes"},{"key":"10.1016\/j.ejphar.2005.06.044_bib8","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1126\/science.7901908","article-title":"Oxidative stress, glutamate, and neurodegenerative disorders","volume":"262","author":"Coyle","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.ejphar.2005.06.044_bib9","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1016\/S0021-9258(18)45880-2","article-title":"Cyclopiazonic acid depletes intracellular Ca2+ stores and activates an influx pathway for divalent cations in HL-60 cells","volume":"267","author":"Demaurex","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib10","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1046\/j.1471-4159.2000.0740960.x","article-title":"Opioids transiently prevent activation of apoptotic mechanisms following short periods of serum withdrawal","volume":"74","author":"Dermitzaki","year":"2000","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib11","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1006\/bbrc.1995.2360","article-title":"Serum withdrawal induces apoptotic cell death in Ki-ras transformed but not in normal differentiated thyroid cells","volume":"214","author":"Di Jeso","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ejphar.2005.06.044_bib12","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1097\/00003246-198907000-00020","article-title":"Unique features of albumin: a brief review","volume":"17","author":"Emerson","year":"1989","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.ejphar.2005.06.044_bib13","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1006\/abio.1994.1184","article-title":"A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry","volume":"218","author":"Gong","year":"1994","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib14","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1161\/01.STR.0000110790.05859.DA","article-title":"Human serum albumin and its N-terminal tetrapeptide (DAHK) block oxidant-induced neuronal death","volume":"35","author":"Gum","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.ejphar.2005.06.044_bib15","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1523\/JNEUROSCI.21-08-02553.2001","article-title":"Calcium-dependent inhibition of L, N, and P\/Q Ca2+ channels in chromaffin cells: role of mitochondria","volume":"21","author":"Hern\u00e1ndez-Guijo","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ejphar.2005.06.044_bib16","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1111\/j.1471-4159.1993.tb13404.x","article-title":"Cell cycle arrest of proliferating neuronal cells by serum deprivation can result in either apoptosis or differentiation","volume":"60","author":"Howard","year":"1993","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib17","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0006-8993(98)00674-X","article-title":"The effect of high-dose albumin therapy on local cerebral perfusion after transient focal cerebral ischemia in rats","volume":"804","author":"Huh","year":"1998","journal-title":"Brain Res."},{"key":"10.1016\/j.ejphar.2005.06.044_bib18","doi-asserted-by":"crossref","first-page":"22912","DOI":"10.1016\/S0021-9258(18)54441-0","article-title":"Drug action of thapsigargin on the calcium pump protein of sarcoplasmic reticulum","volume":"266","author":"Kijima","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib19","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1242\/jcs.107.5.1169","article-title":"Serum deprivation induces apoptotic cell death in a subset of Balb\/c 3 T3 fibroblasts","volume":"107","author":"Kulkarni","year":"1994","journal-title":"J. Cell. Sci."},{"key":"10.1016\/j.ejphar.2005.06.044_bib20","doi-asserted-by":"crossref","first-page":"17067","DOI":"10.1016\/S0021-9258(19)47340-7","article-title":"Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca2+-ATPase family of calcium pumps","volume":"266","author":"Lytton","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib21","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1227\/00006123-199308000-00017","article-title":"Beneficial effect of prolonged administration of albumin on ischemic cerebral edema and infarction after occlusion of middle cerebral artery in rats","volume":"33","author":"Matsui","year":"1993","journal-title":"Neurosurgery"},{"key":"10.1016\/j.ejphar.2005.06.044_bib22","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/35000001","article-title":"Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate secretion","volume":"2","author":"Montero","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ejphar.2005.06.044_bib23","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1046\/j.1365-2141.2002.03280.x","article-title":"Cytoprotective antioxidant activity of serum albumin and autocrine catalase in chronic lymphocytic leukaemia","volume":"116","author":"Moran","year":"2002","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.ejphar.2005.06.044_bib24","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1073\/pnas.92.5.1426","article-title":"Plasma albumin is a potent trigger of calcium signals and DNA synthesis in astrocytes","volume":"92","author":"Nadal","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ejphar.2005.06.044_bib25","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0006-8993(01)03229-2","article-title":"Depletion of intracelullar calcium stores is toxic to SH-SY5Y neuronal cells","volume":"924","author":"Nguyen","year":"2002","journal-title":"Brain Res."},{"key":"10.1016\/j.ejphar.2005.06.044_bib26","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/sj.bjp.0702853","article-title":"Novel antimigraineur dotarizine releases Ca2+ from caffeine-sensitive Ca2+ stores of chromaffin cells","volume":"128","author":"Novalbos","year":"1999","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2005.06.044_bib27","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/S0014-2999(98)00916-9","article-title":"Effects of dotarizine and flunarizine on chromaffin cells viability and cytosolic Ca2+","volume":"366","author":"Novalbos","year":"1999","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2005.06.044_bib28","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1113\/jphysiol.1996.sp021168","article-title":"Two different constituents of plasma increase cytosolic calcium selectively in neurons or glia of primary rat cerebellar cultures","volume":"490","author":"N\u00fa\u00f1ez","year":"1996","journal-title":"J. Physiol."},{"key":"10.1016\/j.ejphar.2005.06.044_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1054\/ceca.2000.0162","article-title":"Dependence of vital cell function on endoplasmic reticulum calcium levels: implications for the mechanisms underlying neuronal cell injury in different pathological states","volume":"29","author":"Paschen","year":"2001","journal-title":"Cell Calcium"},{"key":"10.1016\/j.ejphar.2005.06.044_bib30","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1126\/science.8235595","article-title":"Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria","volume":"262","author":"Rizzuto","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.ejphar.2005.06.044_bib31","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1126\/science.280.5370.1763","article-title":"Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses","volume":"280","author":"Rizzuto","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.ejphar.2005.06.044_bib32","doi-asserted-by":"crossref","first-page":"8619","DOI":"10.1038\/sj.onc.1207105","article-title":"Calcium and apoptosis: facts and hypotheses","volume":"22","author":"Rizzuto","year":"2003","journal-title":"Oncogene"},{"year":"1997","series-title":"Current Protocols in Cytometry","author":"Robinson","key":"10.1016\/j.ejphar.2005.06.044_bib33"},{"key":"10.1016\/j.ejphar.2005.06.044_bib34","doi-asserted-by":"crossref","first-page":"6125","DOI":"10.1523\/JNEUROSCI.16-19-06125.1996","article-title":"Mitochondrial disfunction is a primary event in glutamate neurotoxicity","volume":"16","author":"Schinder","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ejphar.2005.06.044_bib35","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1046\/j.1471-4159.2002.00843.x","article-title":"Albumin promotes neuronal survival by increasing the synthesis and release of glutamate","volume":"81","author":"Tabernero","year":"2002","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib36","doi-asserted-by":"crossref","first-page":"354","DOI":"10.33588\/rn.3504.2002389","article-title":"Papel del poro de permeabilidad transitoria mitocondrial en los procesos neurodegenerativos","volume":"35","author":"Tornero","year":"2002","journal-title":"Rev. Neurol."},{"key":"10.1016\/j.ejphar.2005.06.044_bib37","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1476-5381.1995.tb13236.x","article-title":"Dotarizine versus flunarizine as calcium antagonists in chromaffin cells","volume":"114","author":"Villarroya","year":"1995","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2005.06.044_bib38","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1046\/j.1471-4159.1998.70062305.x","article-title":"Bcl-2 protects against apoptosis in neuronal cell line caused by thapsigargin-induced depletion of intracellular calcium stores","volume":"70","author":"Wei","year":"1998","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ejphar.2005.06.044_bib39","doi-asserted-by":"crossref","first-page":"4533","DOI":"10.1073\/pnas.90.10.4533","article-title":"Bcl-2 inhibits death of central neuronal cells induced by multiple agents","volume":"90","author":"Zhong","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ejphar.2005.06.044_bib40","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0304-4157(95)00003-A","article-title":"The mitochondrial permeability transition","volume":"1241","author":"Zoratti","year":"1995","journal-title":"Biochim. Biophys. Acta"}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299905007193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299905007193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,4]],"date-time":"2025-01-04T15:13:18Z","timestamp":1736003598000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299905007193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9]]},"references-count":40,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2005,9]]}},"alternative-id":["S0014299905007193"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2005.06.044","relation":{},"ISSN":["0014-2999"],"issn-type":[{"type":"print","value":"0014-2999"}],"subject":[],"published":{"date-parts":[[2005,9]]}}}