{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T17:08:31Z","timestamp":1767978511727,"version":"3.49.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1016\/j.ejphar.2008.11.030","type":"journal-article","created":{"date-parts":[[2008,12,3]],"date-time":"2008-12-03T18:10:48Z","timestamp":1228327848000},"page":"117-123","source":"Crossref","is-referenced-by-count":54,"title":["The vasodilator mechanism of sulfur dioxide on isolated aortic rings of rats: Involvement of the K+ and Ca2+ channels"],"prefix":"10.1016","volume":"602","author":[{"given":"Quanxi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziqiang","family":"Meng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2008.11.030_bib1","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.bbrc.2003.10.055","article-title":"Identification of carbonyl sulfide and sulfur dioxide in porcine coronary artery by gas chromatography\/mass spectrometry, possible relevance to EDHF","volume":"311","author":"Balazy","year":"2003","journal-title":"Biochem Biophys. Res. Commun."},{"key":"10.1016\/j.ejphar.2008.11.030_bib2","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0014-2999(79)90134-1","article-title":"A comparison of the inhibitory effect of cinnarizine and papaverine on the noradrenaline and calcium evoked vasoconstriction of isolated rabbit aorta and mesenteric arteries","volume":"53","author":"Broekaert","year":"1979","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib3","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.fct.2004.02.016","article-title":"Effects of derivatives of sulfur dioxide on transient outward potassium currents in acutely isolated rat hippocampal neurons","volume":"42","author":"Du","year":"2004","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib4","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.brainres.2004.03.011","article-title":"Modulation of sodium current in rat dorsal root ganglion neurons by sulfur dioxide derivatives","volume":"1010","author":"Du","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.ejphar.2008.11.030_bib5","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1745-7254.2008.00845.x","article-title":"Endogenously generated sulfur dioxide and its vasorelaxant effect in rats","volume":"29","author":"Du","year":"2008","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.ejphar.2008.11.030_bib6","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1161\/01.ATV.0000125701.18648.48","article-title":"Effect of ATP-sensitive potassium channel inhibition on coronary metabolic vasodilation in humans","volume":"24","author":"Farouque","year":"2004","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib7","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/288373a0","article-title":"The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine","volume":"288","author":"Furchgott","year":"1980","journal-title":"Nature"},{"key":"10.1016\/j.ejphar.2008.11.030_bib8","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/0143-4179(91)90063-O","article-title":"Calcitonin gene-related peptide (CGRP)-induced cyclic AMP, cyclic GMP and vasorelaxant responses in rat thoracic aorta are antagonized by blockers of endothelium-derived relaxant factor (EDRF)","volume":"20","author":"Fiscus","year":"1991","journal-title":"Neuropeptides"},{"key":"10.1016\/j.ejphar.2008.11.030_bib9","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1289\/ehp.02110187","article-title":"Effects of air pollutants on acute stroke mortality","volume":"110","author":"Hong","year":"2002","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ejphar.2008.11.030_bib10","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1097\/00005344-199424020-00020","article-title":"Role of L-type calcium channels on stimulated calcium influx and on proliferative activity of human coronary smooth muscle cells","volume":"24","author":"Kruse","year":"1994","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib11","first-page":"385","article-title":"Tetrandrine is not a selective calcium channel blocker in vascular smooth muscle","volume":"13","author":"Kwan","year":"1992","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.ejphar.2008.11.030_bib12","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.ejphar.2006.10.035","article-title":"Endothelium-independent relaxation to raloxifene in porcine coronary artery","volume":"555","author":"Leung","year":"2007","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib13","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1289\/ehp.00108347","article-title":"Associations between air pollution and mortality in Phoenix. 1995\u20131997","volume":"108","author":"Mar","year":"2000","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.ejphar.2008.11.030_bib14","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1080\/08958370304476","article-title":"Oxidative damage of sulfur dioxide on various organs of mice: sulfur dioxide is a systemic oxidative damage agent","volume":"15","author":"Meng","year":"2003","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib15","series-title":"Ecotoxicology","first-page":"154","author":"Meng","year":"2008"},{"key":"10.1016\/j.ejphar.2008.11.030_bib16","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.etap.2004.10.003","article-title":"Enhancement of sodium metabisulfile on sodium currents in acutely isolated rat hippocampal CAI neurons","volume":"20","author":"Meng","year":"2005","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib17","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.fct.2004.09.008","article-title":"Effects of sodium metabisulfite on potassium currents in acutely isolated CAI pyramidal neurons of rat hippocampus","volume":"43","author":"Meng","year":"2005","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib18","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0027-5107(99)00002-0","article-title":"Polymorase chain reaction based deletion screening of bisulfite (sulfite dioxide)-enhanced gpt-mutants in CHO-AS52 cells","volume":"425","author":"Meng","year":"1999","journal-title":"Mutat. Res."},{"key":"10.1016\/j.ejphar.2008.11.030_bib19","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1093\/mutage\/17.3.215","article-title":"Induction effects of sulfur dioxide inhalation on chromosomal aberrations in mouse bone marrow cells","volume":"17","author":"Meng","year":"2002","journal-title":"Mutagenesis"},{"key":"10.1016\/j.ejphar.2008.11.030_bib20","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1080\/08958370701515175","article-title":"The vasodilator effect and its mechanism of sulfur dioxide-derivatives on isolated aortic rings of rats","volume":"19","author":"Meng","year":"2007","journal-title":"Inhal. Toxicology"},{"key":"10.1016\/j.ejphar.2008.11.030_bib21","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1080\/08958370252809077","article-title":"Micronuclei induced by sulfur dioxide inhalation in mouse bone-marrow cells in vivo","volume":"14","author":"Meng","year":"2002","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib22","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1080\/08958370390215785","article-title":"Blood pressure of rats lowered by sulfur dioxide and its derivatives","volume":"15","author":"Meng","year":"2003","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib23","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1080\/08958370590922625","article-title":"Effect of sulfur dioxide inhalation on cytokine levels in lungs and serum of mice","volume":"17","author":"Meng","year":"2005","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib24","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/em.20142","article-title":"DNA damage in mice treated with sulfur dioxide by inhalation","volume":"46","author":"Meng","year":"2005","journal-title":"Environ. Mol. Mutagen."},{"key":"10.1016\/j.ejphar.2008.11.030_bib25","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.abb.2007.08.028","article-title":"Vasodilatation of sulfur dioxide derivatives and signal transduction","volume":"467","author":"Meng","year":"2007","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.ejphar.2008.11.030_bib26","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s11515-007-0055-x","article-title":"Alterations of gene expression profiles induced by sulfur dioxide in rat lungs","volume":"2","author":"Meng","year":"2007","journal-title":"Front. Biol. China."},{"key":"10.1016\/j.ejphar.2008.11.030_bib28","doi-asserted-by":"crossref","first-page":"C799","DOI":"10.1152\/ajpcell.1995.268.4.C799","article-title":"Physiological roles and properties of potassium channels in arterial smooth muscle","volume":"268","author":"Nelson","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib29","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.fct.2005.08.006","article-title":"Modulation of L-type calcium current in rat cardiac myocytes by sulfur diokicte derivatives","volume":"44","author":"Nie","year":"2006","journal-title":"Food. Chem. Toxicol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib30","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0022-3565(25)22918-4","article-title":"SR 33557, a novel calcium entry blocker. I. In vitro isolated tissue studies","volume":"255","author":"Polster","year":"1990","journal-title":"Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2008.11.030_bib31","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1113\/jphysiol.1996.sp021223","article-title":"Mechanism of inhibition of delayed rectifier K+ current by 4-aminopyridine in rabbit coronary myocytes","volume":"491","author":"Remillard","year":"1996","journal-title":"J. Physiol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib32","first-page":"299","article-title":"Cumulative dose\u2013response curve I. Technique for the making of dose\u2013response curves in isolated organs and the evaluation of drug parameters","volume":"143","author":"Rossum","year":"1963","journal-title":"Arch. Int. Pharmacol."},{"key":"10.1016\/j.ejphar.2008.11.030_bib33","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1161\/01.RES.52.2.137","article-title":"Mechanism of Ca2+ antagonist induced vasodilation. Intracellular actions","volume":"52","author":"Saida","year":"1983","journal-title":"Circ. Res."},{"key":"10.1016\/j.ejphar.2008.11.030_bib34","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1096\/fj.02-0211hyp","article-title":"Two's company, three's a crowd: can H2S be the third endogenous gaseous transmitter","volume":"16","author":"Wang","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.ejphar.2008.11.030_bib35","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1096\/fasebj.11.11.9285481","article-title":"The Hill equation revisited: uses and misuses","volume":"11","author":"Weiss","year":"1997","journal-title":"FASEB J."},{"key":"10.1016\/j.ejphar.2008.11.030_bib36","doi-asserted-by":"crossref","first-page":"6008","DOI":"10.1093\/emboj\/20.21.6008","article-title":"The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener","volume":"20","author":"Zhao","year":"2001","journal-title":"EMBO J."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299908011783?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299908011783?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T02:39:32Z","timestamp":1738723172000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299908011783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["S0014299908011783"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2008.11.030","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}