{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T19:05:31Z","timestamp":1770836731958,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.ejphar.2009.02.043","type":"journal-article","created":{"date-parts":[[2009,3,17]],"date-time":"2009-03-17T08:38:59Z","timestamp":1237279139000},"page":"18-22","source":"Crossref","is-referenced-by-count":16,"title":["Immunohistochemical study on GABAergic system in salivary glands"],"prefix":"10.1016","volume":"610","author":[{"given":"Yasuhiro","family":"Kosuge","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuru","family":"Kawaguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohei","family":"Sawaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Migiwa","family":"Okubo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Shinomiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Sakai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2009.02.043_bib1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0165-6147(99)01413-3","article-title":"The \u2018ABC\u2019 of GABA receptors","volume":"21","author":"Bormann","year":"2000","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.ejphar.2009.02.043_bib2","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein\u2013dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.ejphar.2009.02.043_bib3","doi-asserted-by":"crossref","first-page":"2115","DOI":"10.1073\/pnas.89.6.2115","article-title":"Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene","volume":"89","author":"Bu","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ejphar.2009.02.043_bib4","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1046\/j.1440-1681.1999.03151.x","article-title":"The 'ABC' of GABA receptors: a brief review","volume":"26","author":"Chebib","year":"1999","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib5","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1083\/jcb.118.2.309","article-title":"Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain","volume":"118","author":"Christgau","year":"1992","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib6","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1523\/JNEUROSCI.14-03-01834.1994","article-title":"Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms","volume":"14","author":"Esclapez","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ejphar.2009.02.043_bib7","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/cne.902720404","article-title":"GABAergic basal forebrain neurons project to the neocortex: the localization of glutamic acid decarboxylase and choline acetyltransferase in feline corticopetal neurons","volume":"272","author":"Fisher","year":"1988","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib8","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/sj.bjp.0702524","article-title":"Effects of GABA on noradrenaline release and vasoconstriction induced by renal nerve stimulation in isolated perfused rat kidney","volume":"127","author":"Fujimura","year":"1999","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib9","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1159\/000070897","article-title":"Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors","volume":"77","author":"Geigerseder","year":"2003","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.ejphar.2009.02.043_bib10","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/BF00271357","article-title":"Localization of GAD-like immunoreactivity in the pancreas and stomach of the rat and mouse","volume":"96","author":"Gilon","year":"1991","journal-title":"Histochemistry"},{"key":"10.1016\/j.ejphar.2009.02.043_bib11","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1002\/cne.903290403","article-title":"Codistribution of GABA\u2014with acetylcholine-synthesizing neurons in the basal forebrain of the rat","volume":"329","author":"Gritti","year":"1993","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib12","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/0306-4522(86)90297-6","article-title":"Colocalization of gamma-aminobutyric acid and acetylcholinesterase in rodent cortical neurons","volume":"19","author":"Hallanger","year":"1986","journal-title":"Neuroscience"},{"key":"10.1016\/j.ejphar.2009.02.043_bib13","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1292\/jvms.61.631","article-title":"Colocalization of gamma-aminobutyric acid immunoreactivity and acetylcholinesterase activity in nerve fibers of the mouse adrenal gland","volume":"61","author":"Iwasa","year":"1999","journal-title":"J. Vet. Med. Sci."},{"key":"10.1016\/j.ejphar.2009.02.043_bib14","first-page":"291","article-title":"Coupling of benzodiazepine and GABA(A) receptors in the salivary glands is a factor of drug-induced Xerostomia","volume":"11","author":"Kawaguchi","year":"1996","journal-title":"Int. Acad. Biomed. Drud. Res."},{"key":"10.1016\/j.ejphar.2009.02.043_bib15","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.neuroscience.2003.08.026","article-title":"S-allyl-L-cysteine selectively protects cultured rat hippocampal neurons from amyloid beta-protein- and tunicamycin-induced neuronal death","volume":"122","author":"Kosuge","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.ejphar.2009.02.043_bib16","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1038\/sj.bjp.0704968","article-title":"Inhibitory effect of diazepam on muscarinic receptor-stimulated inositol 1,4,5-trisphosphate production in rat parotid acinar cells","volume":"137","author":"Kujirai","year":"2002","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib17","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0014-2999(98)00628-1","article-title":"Inhibitory regulation of amylase release in rat parotid acinar cells by benzodiazepine receptors","volume":"359","author":"Okubo","year":"1998","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib18","first-page":"291","article-title":"Occurrence of GABA in rat testis and its effect on androgen production","volume":"42","author":"Ritta","year":"1986","journal-title":"Adv. Biochem. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib19","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1254\/jjp.67.359","article-title":"Existence of gamma-aminobutyric acid and its biosynthetic and metabolic enzymes in rat salivary glands","volume":"67","author":"Sawaki","year":"1995","journal-title":"Jpn. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib20","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0169-328X(95)00138-I","article-title":"Role of amino acids in salivation and the localization of their receptors in the rat salivary gland","volume":"33","author":"Shida","year":"1995","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.ejphar.2009.02.043_bib21","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S0165-6147(98)01270-X","article-title":"Two isoforms of glutamate decarboxylase: why?","volume":"19","author":"Soghomonian","year":"1998","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.ejphar.2009.02.043_bib22","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.2337\/diabetes.40.11.1365","article-title":"Structural and functional considerations of GABA in islets of Langerhans. Beta-cells and nerves","volume":"40","author":"Sorenson","year":"1991","journal-title":"Diabetes"},{"key":"10.1016\/j.ejphar.2009.02.043_bib23","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1741-2358.1986.tb00055.x","article-title":"A reference guide to drugs and dry mouth","volume":"5","author":"Sreebny","year":"1986","journal-title":"Gerodontology"},{"key":"10.1016\/j.ejphar.2009.02.043_bib24","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/274383a0","article-title":"GABAergic modulation of benzodiazepine binding site sensitivity","volume":"274","author":"Tallman","year":"1978","journal-title":"Nature"},{"key":"10.1016\/j.ejphar.2009.02.043_bib25","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1146\/annurev.pa.29.040189.001515","article-title":"Peripheral type benzodiazepine receptors","volume":"29","author":"Verma","year":"1989","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0074-7696(02)13011-7","article-title":"GABA and GABA receptors in the central nervous system and other organs","volume":"213","author":"Watanabe","year":"2002","journal-title":"Int. Rev. Cytol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib27","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0006-2952(97)00433-4","article-title":"Characterization of central- and peripheral-type benzodiazepine receptors in rat salivary glands","volume":"55","author":"Yamagishi","year":"1998","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib28","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1254\/jjp.82.110","article-title":"Pharmacological characterization of an 18-kDa protein associated with the peripheral-type benzodiazepine receptor in salivary glands","volume":"82","author":"Yamagishi","year":"2000","journal-title":"Jpn. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2009.02.043_bib29","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/j.1365-2567.2005.02212.x","article-title":"Lipopolysaccharide-induced elevation and secretion of interleukin-1\u03b2 in the submandibular gland of male mice","volume":"116","author":"Yao","year":"2005","journal-title":"Immunology"},{"key":"10.1016\/j.ejphar.2009.02.043_bib30","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.molbrainres.2004.06.015","article-title":"Distribution and MK-801-induced expression of serine racemase mRNA in rat brain by real-time quantitative PCR","volume":"128","author":"Yoshikawa","year":"2004","journal-title":"Brain Res. Mol. Brain Res."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299909002374?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299909002374?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,18]],"date-time":"2019-05-18T21:15:01Z","timestamp":1558214101000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299909002374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":30,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S0014299909002374"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2009.02.043","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}