{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T20:10:05Z","timestamp":1791144605155,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1016\/j.ejphar.2010.05.050","type":"journal-article","created":{"date-parts":[[2010,6,14]],"date-time":"2010-06-14T04:31:06Z","timestamp":1276489866000},"page":"93-98","source":"Crossref","is-referenced-by-count":80,"title":["Effect of 5-aza-2-deoxycytidine microinjecting into hippocampus and prelimbic cortex on acquisition and retrieval of cocaine-induced place preference in C57BL\/6 mice"],"prefix":"10.1016","volume":"642","author":[{"given":"Jin","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonghui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuguang","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Sui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2010.05.050_bib1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s002130000569","article-title":"Conditioned place preference: what does it add to our preclinical understanding of drug reward?","volume":"153","author":"Bardo","year":"2000","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ejphar.2010.05.050_bib2","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/23270","article-title":"Time-dependent reorganization of brain circuitry underlying long-term memory storage","volume":"400","author":"Bontempi","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.ejphar.2010.05.050_bib3","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.neulet.2008.05.028","article-title":"Regional-specific global cytosine methylation and DNA methyltransferase expression in the adult rat hippocampus","volume":"440","author":"Brown","year":"2008","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ejphar.2010.05.050_bib4","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1124\/mol.106.022301","article-title":"Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain","volume":"70","author":"Cassel","year":"2006","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ejphar.2010.05.050_bib5","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1002\/hipo.20216","article-title":"Morphine conditioned place preference depends on glucocorticoid receptors in both hippocampus and nucleus accumbens","volume":"16","author":"Dong","year":"2006","journal-title":"Hippocampus"},{"key":"10.1016\/j.ejphar.2010.05.050_bib6","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1523\/JNEUROSCI.20-09-03175.2000","article-title":"DNA methyltransferase contributes to delayed ischemic brain injury","volume":"20","author":"Endres","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ejphar.2010.05.050_bib7","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.nlm.2007.05.006","article-title":"NMDA receptor blockade in the basolateral amygdala disrupts consolidation of stimulus-reward memory and extinction learning during reinstatement of cocaine-seeking in an animal model of relapse","volume":"88","author":"Feltenstein","year":"2007","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.ejphar.2010.05.050_bib8","doi-asserted-by":"crossref","first-page":"e65","DOI":"10.1371\/journal.pgen.0020065","article-title":"DNA methylation supports intrinsic epigenetic memory in mammalian cells","volume":"2","author":"Feng","year":"2006","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ejphar.2010.05.050_bib9","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1073\/pnas.0510133103","article-title":"Fast track to the medial prefrontal cortex","volume":"103","author":"Frankland","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.ejphar.2010.05.050_bib10","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1101\/lm.183406","article-title":"Stability of recent and remote contextual fear memory","volume":"13","author":"Frankland","year":"2006","journal-title":"Learn. Mem."},{"key":"10.1016\/j.ejphar.2010.05.050_bib11","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1038\/sj.npp.1300579","article-title":"The role of the dorsomedial prefrontal cortex, basolateral amygdala, and dorsal hippocampus in contextual reinstatement of cocaine seeking in rats","volume":"30","author":"Fuchs","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ejphar.2010.05.050_bib12","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1601-183X.2007.00338.x","article-title":"Transcriptional responses to reinforcing effects of cocaine in the rat hippocampus and cortex","volume":"7","author":"Krasnova","year":"2008","journal-title":"Genes Brain Behav."},{"key":"10.1016\/j.ejphar.2010.05.050_bib13","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.neuron.2005.09.023","article-title":"Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum","volume":"48","author":"Kumar","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.ejphar.2010.05.050_bib14","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.nlm.2006.06.004","article-title":"Cocaine\u2014but not methamphetamine-associated memory requires de novo protein synthesis","volume":"87","author":"Kuo","year":"2007","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.ejphar.2010.05.050_bib15","doi-asserted-by":"crossref","first-page":"15,763","DOI":"10.1074\/jbc.M511767200","article-title":"Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus","volume":"281","author":"Levenson","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2010.05.050_bib16","doi-asserted-by":"crossref","first-page":"10,576","DOI":"10.1523\/JNEUROSCI.1786-08.2008","article-title":"Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory","volume":"28","author":"Lubin","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ejphar.2010.05.050_bib17","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.pnpbp.2007.02.012","article-title":"Effect of memantine and CNQX in the acquisition, expression and reinstatement of cocaine-induced conditioned place preference","volume":"31","author":"Maldonado","year":"2007","journal-title":"Prog. Neuro-Psychoph."},{"key":"10.1016\/j.ejphar.2010.05.050_bib18","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0304-3940(03)00307-0","article-title":"Fos but not Cart (cocaine and amphetamine regulated transcript) is overexpressed by several drugs of abuse: a comparative study using real-time quantitative polymerase chain reaction in rat brain","volume":"345","author":"Marie-Claire","year":"2003","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ejphar.2010.05.050_bib19","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/BF02244907","article-title":"Animal models of drug craving","volume":"112","author":"Markou","year":"1993","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.ejphar.2010.05.050_bib20","doi-asserted-by":"crossref","first-page":"1,8561","DOI":"10.1073\/pnas.0806078105","article-title":"Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology","volume":"105","author":"Meyer","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U S A"},{"key":"10.1016\/j.ejphar.2010.05.050_bib21","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1037\/0735-7044.120.2.401","article-title":"Dorsal hippocampus inhibition disrupts acquisition and expression, but not consolidation, of cocaine conditioned place preference","volume":"120","author":"Meyers","year":"2006","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.ejphar.2010.05.050_bib22","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1111\/j.1460-9568.2005.03974.x","article-title":"Altered Fos expression in neural pathways underlying cue-elicited drug seeking in the rat","volume":"21","author":"Miller","year":"2005","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.ejphar.2010.05.050_bib23","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.neuron.2007.02.022","article-title":"Covalent modification of DNA regulates memory formation","volume":"53","author":"Miller","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.ejphar.2010.05.050_bib24","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.nlm.2007.07.016","article-title":"DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity","volume":"89","author":"Miller","year":"2008","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.ejphar.2010.05.050_bib25","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0163-7258(85)90052-X","article-title":"Clinical trial on 5-aza-2\u2032-deoxycytidine in patients with acute leukemia","volume":"30","author":"Momparler","year":"1985","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.ejphar.2010.05.050_bib26","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1523\/JNEUROSCI.3796-07.2008","article-title":"Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation","volume":"28","author":"Nelson","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ejphar.2010.05.050_bib27","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.neulet.2006.12.052","article-title":"Methamphetamine alters expression of DNA methyltransferase 1 mRNA in rat brain","volume":"414","author":"Numachi","year":"2007","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ejphar.2010.05.050_bib28","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0006-8993(03)02230-3","article-title":"Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine","volume":"970","author":"Peakman","year":"2003","journal-title":"Brain Res."},{"key":"10.1016\/j.ejphar.2010.05.050_bib29","doi-asserted-by":"crossref","first-page":"e8798","DOI":"10.1371\/journal.pone.0008798","article-title":"The site specific demethylation in the 5\u2032-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription","volume":"5","author":"Qiang","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ejphar.2010.05.050_bib30","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.molmed.2008.06.004","article-title":"Epigenetic mechanisms in drug addiction","volume":"14","author":"Renthal","year":"2008","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.ejphar.2010.05.050_bib31","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1177\/0269881103174005","article-title":"Involvement of dopamine receptors of the dorsal hippocampus on the acquisition and expression of morphine-induced place preference in rats","volume":"17","author":"Rezayof","year":"2003","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2010.05.050_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1441.020","article-title":"Drug addiction and the memory systems of the brain","volume":"1141","author":"Robbins","year":"2008","journal-title":"Ann. NY Acad. Sci."},{"key":"10.1016\/j.ejphar.2010.05.050_bib33","doi-asserted-by":"crossref","first-page":"74","DOI":"10.4161\/epi.3.2.6103","article-title":"Depolarization induces downregulation of DNMT1 and DNMT3a in primary cortical cultures","volume":"3","author":"Sharma","year":"2008","journal-title":"Epigenetics"},{"key":"10.1016\/j.ejphar.2010.05.050_bib34","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/nrn2132","article-title":"Epigenetic regulation in psychiatric disorders","volume":"8","author":"Tsankova","year":"2007","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ejphar.2010.05.050_bib35","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0166-4328(98)00034-5","article-title":"Discrete quinolinic acid lesions of the rat prelimbic medial prefrontal cortex affect cocaine- and MK-801-, but not morphine- and amphetamine-induced reward and psychomotor activation as measured with the place preference conditioning paradigm","volume":"97","author":"Tzschentke","year":"1998","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ejphar.2010.05.050_bib36","doi-asserted-by":"crossref","first-page":"4099","DOI":"10.1046\/j.1460-9568.1999.00834.x","article-title":"Functional heterogeneity of the rat medial prefrontal cortex: effects of discrete subarea-specific lesions on drug-induced conditioned place preference and behavioural sensitization","volume":"11","author":"Tzschentke","year":"1999","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.ejphar.2010.05.050_bib37","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1126\/science.270.5237.769","article-title":"Functional brain imaging studies of cortical mechanisms for memory","volume":"270","author":"Ungerleider","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.ejphar.2010.05.050_bib38","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0006-8993(03)03452-8","article-title":"Role of the prelimbic subregion of the medial prefrontal cortex in acquisition, extinction, and reinstatement of cocaine-conditioned place preference","volume":"990","author":"Zavala","year":"2003","journal-title":"Brain Res."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299910005017?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299910005017?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T22:56:24Z","timestamp":1559170584000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299910005017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":38,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["S0014299910005017"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2010.05.050","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}