{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:18:31Z","timestamp":1787242711490,"version":"build-2736575974"},"reference-count":29,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1016\/j.ejphar.2010.07.034","type":"journal-article","created":{"date-parts":[[2010,8,3]],"date-time":"2010-08-03T05:22:21Z","timestamp":1280812941000},"page":"143-150","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":143,"title":["Sulfur dioxide upregulates the aortic nitric oxide pathway in rats"],"prefix":"10.1016","volume":"645","author":[{"given":"Junling","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqiang","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2010.07.034_bb0005","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.yrtph.2005.09.002","article-title":"Effects of sulfur dioxide on apoptosis-related gene expressions in lungs from rats","volume":"l43","author":"Bai","year":"2005","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0010","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.bbrc.2003.10.055","article-title":"Identification of carbonyl sulfide and sulfur dioxide in porcine coronary artery by gas chromatography\/mass spectrometry, possible relevance to EDHF","volume":"311","author":"Balazy","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0015","first-page":"160","article-title":"Endothelial function and hemostasis","volume":"89","author":"Becker","year":"2000","journal-title":"Z. Kardiol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0020","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein\u2013dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0025","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/21218","article-title":"Regulation of endothelium-derived nitric oxide production by the protein kinase Akt","volume":"399","author":"Fulton","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.ejphar.2010.07.034_bb0035","doi-asserted-by":"crossref","first-page":"R1608","DOI":"10.1152\/ajpregu.00207.2006","article-title":"Hydrogen sulfide downregulates the aortic l-arginine\/nitric oxide pathway in rats","volume":"293","author":"Geng","year":"2007","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0040","doi-asserted-by":"crossref","first-page":"F193","DOI":"10.1152\/ajprenal.2001.280.2.F193","article-title":"Cellular regulation of endothelial nitric oxide synthase","volume":"280","author":"Govers","year":"2001","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0045","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1039\/b106209n","article-title":"Use of rosaniline hydrochloride dye for atmospheric SO2 determination and method sensitivity analysis","volume":"3","author":"Goyal","year":"2001","journal-title":"J. Environ. Monit."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0050","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/sj.bjp.0706177","article-title":"The role of nitric oxide synthase in reduced vasocontractile responsiveness induced by prolonged a1-adrenergic receptor stimulation in rat thoracic aorta","volume":"145","author":"G\u00fcrdal","year":"2005","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0055","doi-asserted-by":"crossref","first-page":"9265","DOI":"10.1073\/pnas.84.24.9265","article-title":"Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide","volume":"84","author":"Ignarro","year":"1987","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.ejphar.2010.07.034_bb0150","first-page":"385","article-title":"Tetrandrine is not a selective calcium channel blocker in vascular smooth muscle","volume":"13","author":"Kwan","year":"1992","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0060","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.niox.2008.12.003","article-title":"The role of sulfur dioxide as an endogenous gaseous vasoactive factor in synergy with nitric oxide","volume":"20","author":"Li","year":"2009","journal-title":"Nitric Oxide Biol. Chem."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0065","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s00726-009-0264-5","article-title":"Amino acids and gaseous signaling","volume":"37","author":"Li","year":"2009","journal-title":"Amino Acids"},{"key":"10.1016\/j.ejphar.2010.07.034_bb0070","doi-asserted-by":"crossref","first-page":"3264","DOI":"10.1074\/jbc.273.6.3264","article-title":"A new pathway of nitric oxide\/cyclic GMP signaling involving S-nitrosoglutathione","volume":"273","author":"Mayer","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0075","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1080\/08958370304476","article-title":"Oxidative damage of sulfur dioxide on various organs of mice: sulfur dioxide is a systemic oxidative damage agent","volume":"15","author":"Meng","year":"2003","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0080","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1080\/08958370390215785","article-title":"Blood pressure of rats lowered by sulfur dioxide and its derivatives","volume":"15","author":"Meng","year":"2003","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0085","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.abb.2007.08.028","article-title":"Vasodilatation of sulfur dioxide derivatives and signal transduction","volume":"467","author":"Meng","year":"2007","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0090","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.3109\/08958370902798463","article-title":"Vasodilator effect of gaseous sulfur dioxide and regulation of its level by Ach in rat vascular tissues","volume":"21","author":"Meng","year":"2009","journal-title":"Inhal. Toxicol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0095","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1097\/01.shk.0000105501.75189.85","article-title":"Increased levels of serum sulfite in patients with acute pneumonia","volume":"21","author":"Mitsuhashi","year":"2004","journal-title":"Shock"},{"key":"10.1016\/j.ejphar.2010.07.034_bb0100","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.yrtph.2006.02.006","article-title":"The expressions of protooncogenes and CYP1A in lungs of rats exposed to sulfur dioxide and benzo(a)pyrene","volume":"45","author":"Qin","year":"2007","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0105","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.neuint.2007.05.016","article-title":"Hydrogen sulfide: neurochemistry and neurobiology","volume":"52","author":"Qu","year":"2008","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0110","doi-asserted-by":"crossref","first-page":"C142","DOI":"10.1152\/ajpcell.00589.2006","article-title":"l-Glutamine in vitro regulates rat aortic glutamate content and modulates nitric oxide formation and contractility responses","volume":"293","author":"Schachter","year":"2007","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0115","doi-asserted-by":"crossref","first-page":"C803","DOI":"10.1152\/ajpcell.00457.2005","article-title":"Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression","volume":"291","author":"Searles","year":"2006","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0120","doi-asserted-by":"crossref","first-page":"1652S","DOI":"10.1093\/jn\/136.6.1652S","article-title":"Mammalian cysteine metabolism: new insights into regulation of cysteine metabolism","volume":"136","author":"Stipanuk","year":"2006","journal-title":"J. Nutr."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0125","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00726-008-0202-y","article-title":"Cysteine dioxygenase: a robust system for regulation of cellular cysteine levels","volume":"37","author":"Stipanuk","year":"2009","journal-title":"Amino Acids"},{"key":"10.1016\/j.ejphar.2010.07.034_bb0130","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0195-668X(02)00808-4","article-title":"The association of daily sulfur dioxide air pollution levels with hospital admissions for cardiovascular diseases in Europe (the Aphea-II study)","volume":"24","author":"Sunyer","year":"2003","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0135","first-page":"948","article-title":"Lipoteichoic acid from Staphylococcus aureus depresses contractile function of human arteries in vitro due to the induction of nitric oxide synthase","volume":"82","author":"Tsuneyoshi","year":"1996","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0140","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1046\/j.1538-7836.2003.00345.x","article-title":"Nitric oxide in vascular biology","volume":"1","author":"Walford","year":"2003","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.ejphar.2010.07.034_bb0145","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ejphar.2008.11.030","article-title":"The vasodilator mechanism of sulfur dioxide on isolated aortic rings of rats: involvement of the K+ and Ca2+ channels","volume":"602","author":"Zhang","year":"2009","journal-title":"Eur. J. Pharmacol."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299910007533?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299910007533?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T22:12:30Z","timestamp":1757974350000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299910007533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":29,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["S0014299910007533"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2010.07.034","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2010,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sulfur dioxide upregulates the aortic nitric oxide pathway in rats","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2010.07.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}