{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T01:49:19Z","timestamp":1777081759363,"version":"3.51.4"},"reference-count":40,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1016\/j.ejphar.2010.10.089","type":"journal-article","created":{"date-parts":[[2010,11,30]],"date-time":"2010-11-30T10:38:16Z","timestamp":1291113496000},"page":"111-116","source":"Crossref","is-referenced-by-count":10,"title":["Hydrocortisone administration increases pulmonary artery pressure in asphyxiated newborn piglets reoxygenated with 100% oxygen"],"prefix":"10.1016","volume":"652","author":[{"given":"Isabelle","family":"Chapados","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tze-Fun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constance L.","family":"Chik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po-Yin","family":"Cheung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2010.10.089_bb0005","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1210\/endo-108-3-977","article-title":"Glucocorticoid regulation of myocardial beta-adrenergic receptors","volume":"108","author":"Abrass","year":"1981","journal-title":"Endocrinology"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0010","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1046\/j.1365-2125.1998.00833.x","article-title":"Impaired pressor sensitivity to noradrenaline in septic shock patients with and without impaired adrenal function reserve","volume":"46","author":"Annane","year":"1998","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0015","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1001\/jama.283.8.1038","article-title":"A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin","volume":"283","author":"Annane","year":"2000","journal-title":"JAMA"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0020","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD002243.pub2","article-title":"Corticosteroids for treating severe sepsis and septic shock","author":"Annane","year":"2004","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0025","series-title":"Basic and Clinical Endocrinology","first-page":"362","article-title":"Glucocorticoids and adrenal androgens","author":"Aron","year":"2004"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0030","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/sj.jp.7211225","article-title":"Hypotension in the newborn: who needs hydrocortisone?","volume":"25","author":"Aucott","year":"2005","journal-title":"J. Perinatol."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0035","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1097\/00005237-200604000-00011","article-title":"Brain injury in the infant: the old, the new, and the uncertain","volume":"20","author":"Badr Zahr","year":"2006","journal-title":"J. Perinat. Neonatal Nurs."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0040","series-title":"(Abstract) EPAS 2005:57:585","article-title":"Evaluation of hydrocortisone in neonates with pressor resistant hypotension","author":"Baker","year":"2005"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0045","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1016\/j.freeradbiomed.2004.07.029","article-title":"Peroxynitrite inhibits relaxation and induces pulmonary artery muscle contraction in the newborn rat","volume":"37","author":"Belik","year":"2004","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0050","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1345\/aph.1C435","article-title":"Role of corticosteroids in septic shock","volume":"38","author":"Burry","year":"2004","journal-title":"Ann. Pharmacother."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0055","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/SHK.0b013e3181c99727","article-title":"Plasma cortisol response to ACTH challenge in hypoxic newborn piglets resuscitated with 21% and 100% oxygen","volume":"33","author":"Chapados","year":"2010","journal-title":"Shock"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0060","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/S0002-9149(97)00144-6","article-title":"Dobutamine pharmacokinetics during dobutamine stress echocardiography","volume":"79","author":"Daly","year":"1997","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0065","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/sj.jp.7211193","article-title":"A randomized-controlled trial of prophylactic hydrocortisone supplementation for the prevention of hypotension in extremely low birth weight infants","volume":"25","author":"Efird","year":"2005","journal-title":"J. Perinatol."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0070","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/sj.jp.7211211","article-title":"Prevalence of low cortisol values in term and near-term infants with vasopressor-resistant hypotension","volume":"25","author":"Fernandez","year":"2005","journal-title":"J. Perinatol."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0075","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1161\/01.RES.85.10.906","article-title":"Vascular matrix metalloproteinase-2 cleaves big endothelin-1 yielding a novel vasoconstrictor","volume":"85","author":"Fernandez-Patron","year":"1999","journal-title":"Circ. Res."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0080","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.ijcard.2005.11.109","article-title":"A role for matrix metalloproteinase-9 in the hemodynamic changes following acute pulmonary embolism","volume":"114","author":"Fortuna","year":"2007","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0085","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.cardiores.2003.11.026","article-title":"The endothelin system in pulmonary arterial hypertension","volume":"61","author":"Galie","year":"2004","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0090","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/01.shk.0000158962.83529.ce","article-title":"Cardiac function, myocardial glutathione, and matrix metalloproteinase-2 levels in hypoxic newborn pigs reoxygenated by 21%, 50%, or 100% oxygen","volume":"23","author":"Haase","year":"2005","journal-title":"Shock"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0095","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1097\/01.CCM.0000189743.55352.0E","article-title":"Hydrocortisone increases the sensitivity to alpha1-adrenoceptor stimulation in humans following hemorrhagic shock","volume":"33","author":"Hoen","year":"2005","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0100","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/01.mop.0000236397.79580.85","article-title":"Adrenal insufficiency in the critically ill neonate and child","volume":"18","author":"Langer","year":"2006","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0105","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1067\/mpd.2002.122730","article-title":"Neurodevelopmental and medical outcomes of persistent pulmonary hypertension in term newborns treated with nitric oxide","volume":"140","author":"Lipkin","year":"2002","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0110","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/S0022-3476(95)70174-5","article-title":"Multiple organ involvement in perinatal asphyxia","volume":"127","author":"Martin-Ancel","year":"1995","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0115","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1542\/peds.2005-0869","article-title":"A double-blind, randomized, controlled study of a \u201cstress dose\u201d of hydrocortisone for rescue treatment of refractory hypotension in preterm infants","volume":"117","author":"Ng","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0120","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1007\/BF02820871","article-title":"Effects of methylprednisolone on hemodynamics and beta-adrenergic receptor signaling in rabbits with acute left ventricular failure","volume":"12","author":"Nishimura","year":"1997","journal-title":"Heart Vessels"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0125","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.earlhumdev.2005.03.007","article-title":"Pathophysiology of newborn hypotension outside the transitional period","volume":"81","author":"Noori","year":"2005","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0130","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1542\/peds.2006-0661","article-title":"Hemodynamic changes after low-dosage hydrocortisone administration in vasopressor-treated preterm and term neonates","volume":"118","author":"Noori","year":"2006","journal-title":"Pediatrics"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0135","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1159\/000088289","article-title":"Cardiovascular effects of low-dose dexamethasone in very low birth weight neonates with refractory hypotension","volume":"89","author":"Noori","year":"2006","journal-title":"Biol. Neonate"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0140","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.earlhumdev.2005.03.009","article-title":"Diagnosis and treatment of preterm transitional circulatory compromise","volume":"81","author":"Osborn","year":"2005","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0145","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1097\/01.CCM.0000159854.23324.84","article-title":"Absolute and relative adrenal insufficiency in children with septic shock","volume":"33","author":"Pizarro","year":"2005","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0150","doi-asserted-by":"crossref","first-page":"10043","DOI":"10.1073\/pnas.87.24.10043","article-title":"Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells","volume":"87","author":"Radomski","year":"1990","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.ejphar.2010.10.089_bb0155","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/BF01701473","article-title":"Corticosteroid effect on early beta-adrenergic down-regulation during circulatory shock: hemodynamic study and beta-adrenergic receptor assay","volume":"21","author":"Saito","year":"1995","journal-title":"Intensive Care Med."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0160","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/00008480-200104000-00005","article-title":"Controversies in the diagnosis and management of hypotension in the newborn infant","volume":"13","author":"Seri","year":"2001","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0165","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.earlhumdev.2005.03.008","article-title":"Diagnosis and treatment of neonatal hypotension outside the transitional period","volume":"81","author":"Seri","year":"2005","journal-title":"Early Hum. Dev."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0170","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003662.pub3","article-title":"Corticosteroids for treating hypotension in preterm infants","author":"Subhedar","year":"2007","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0175","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1097\/01.PCC.0000185487.69215.29","article-title":"Hemodynamic effects of rescue protocol hydrocortisone in neonates with low cardiac output syndrome after cardiac surgery","volume":"6","author":"Suominen","year":"2005","journal-title":"Pediatr. Crit. Care Med."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0180","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/sj.jp.7200202","article-title":"Low serum cortisol in term newborns with refractory hypotension","volume":"19","author":"Tantivit","year":"1999","journal-title":"J. Perinatol."},{"issue":"5 Suppl. 1","key":"10.1016\/j.ejphar.2010.10.089_bb0185","first-page":"S238","article-title":"Glucocorticoids decrease endothelin-A- and -B-receptor expression in the kidney","volume":"36","author":"Villeneuve","year":"2000","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0190","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1146\/annurev.physiol.59.1.365","article-title":"Specific, nongenomic actions of steroid hormones","volume":"59","author":"Wehling","year":"1997","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0195","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/sj.bjp.0703834","article-title":"Nitric oxide-mediated modulation of the endothelin-1 signalling pathway in the human cardiovascular system","volume":"132","author":"Wiley","year":"2001","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2010.10.089_bb0200","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1559-4572.2008.07263.x","article-title":"Environmental stress, erythrocyte dysfunctions, inflammation, and the metabolic syndrome: adaptations to CO2 increases?","volume":"3","author":"Zappulla","year":"2008","journal-title":"J. Cardiometab. Syndr."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299910011416?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299910011416?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,14]],"date-time":"2021-11-14T10:44:25Z","timestamp":1636886665000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299910011416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":40,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S0014299910011416"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2010.10.089","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2]]}}}