{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T13:28:57Z","timestamp":1778160537360,"version":"3.51.4"},"reference-count":23,"publisher":"Elsevier BV","issue":"1-3","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.ejphar.2012.10.036","type":"journal-article","created":{"date-parts":[[2012,11,2]],"date-time":"2012-11-02T05:12:52Z","timestamp":1351833172000},"page":"206-212","source":"Crossref","is-referenced-by-count":21,"title":["Neuropeptide Y is analgesic in rats after plantar incision"],"prefix":"10.1016","volume":"698","author":[{"given":"Suraj M.","family":"Yalamuri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Brennan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina M.","family":"Spofford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2012.10.036_bib1","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1213\/01.ANE.0000068822.10113.9E","article-title":"Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged","volume":"97","author":"Apfelbaum","year":"2003","journal-title":"Anesth. Analg."},{"key":"10.1016\/j.ejphar.2012.10.036_bib2","doi-asserted-by":"crossref","first-page":"3202","DOI":"10.1016\/j.peptides.2006.07.020","article-title":"Anxiolytic-like effect of the selective Neuropeptide Y Y2 receptor antagonist BIIE0246 in the elevated plus-maze","volume":"27","author":"Bacchi","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.ejphar.2012.10.036_bib3","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1136\/bjsm.2008.055780","article-title":"Presence of the neuropeptide Y1 receptor in tenocytes and blood vessel walls in the human Achilles tendon","volume":"43","author":"Bjur","year":"2009","journal-title":"Br. J. Sports Med."},{"key":"10.1016\/j.ejphar.2012.10.036_bib4","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/0304-3959(95)01441-1","article-title":"Characterization of a rat model of incisional pain","volume":"64","author":"Brennan","year":"1996","journal-title":"Pain"},{"key":"10.1016\/j.ejphar.2012.10.036_bib5","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.tips.2006.12.003","article-title":"Neuropeptide tyrosine and pain","volume":"28","author":"Brumovsky","year":"2007","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.ejphar.2012.10.036_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0014-2999(98)00242-8","article-title":"Neuropeptide Y Y1 receptors in vascular pharmacology","volume":"349","author":"Franco-Cereceda","year":"1998","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2012.10.036_bib7","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/sj.bjp.0706967","article-title":"Neuropeptide Y modulates effects of bradykinin and prostaglandin E2 on trigeminal nociceptors via activation of the Y1 and Y2 receptors","volume":"150","author":"Gibbs","year":"2007","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2012.10.036_bib8","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.pain.2006.04.013","article-title":"Attenuation of capsaicin-evoked mechanical allodynia by peripheral neuropeptide Y Y1 receptors","volume":"124","author":"Gibbs","year":"2006","journal-title":"Pain"},{"key":"10.1016\/j.ejphar.2012.10.036_bib9","first-page":"R546","article-title":"Neuropeptide Y and neurovascular control in skeletal muscle and skin","volume":"297","author":"Hodges","year":"2009","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.ejphar.2012.10.036_bib10","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.bbr.2005.09.024","article-title":"Interleukin-1\u03b1\u03b2 gene-deficient mice show reduced nociceptive sensitivity in models of inflammatory and neuropathic pain but not post-operative pain","volume":"167","author":"Honore","year":"2006","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ejphar.2012.10.036_bib11","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.pain.2007.09.016","article-title":"Intrathecal neuropeptide Y reduces behavioral and molecular markers of inflammatory or neuropathic pain","volume":"137","author":"Intondi","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.ejphar.2012.10.036_bib12","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.neuroscience.2009.10.052","article-title":"Topography and time course of changes in spinal neuropeptide Y immunoreactivity after spared nerve injury","volume":"165","author":"Intondi","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.ejphar.2012.10.036_bib13","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1016\/S0014-2999(00)00230-2","article-title":"Effect of a selective neuropeptide Y Y2 receptor antagonist, BIIE0246 on neuropeptide Y release","volume":"396","author":"King","year":"2000","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2012.10.036_bib14","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.nut.2008.06.022","article-title":"Y1 receptor knockout increases nociception and prevents the anti-allodynic actions of NPY","volume":"24","author":"Kuphal","year":"2008","journal-title":"Nutrition"},{"key":"10.1016\/j.ejphar.2012.10.036_bib15","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1006\/exnr.1999.7329","article-title":"Effect of axotomy on expression of NPY, galanin, and NPY Y1 and Y2 receptors in dorsal root ganglia and the superior cervical ganglion studied with double-labeling in situ hybridization and immunohistochemistry","volume":"162","author":"Landry","year":"2000","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.ejphar.2012.10.036_bib16","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.neuroscience.2003.09.017","article-title":"Involvement of peripheral neuropeptide Y receptors in sympathetic modulation of acute cutaneous flare induced by intradermal capsaicin","volume":"123","author":"Lin","year":"2004","journal-title":"Neuroscience"},{"key":"10.1016\/j.ejphar.2012.10.036_bib18","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0304-3940(83)90401-9","article-title":"High levels of neuropeptide Y in peripheral noradrenergic neurons in various mammals including man","volume":"42","author":"Lundberg","year":"1983","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ejphar.2012.10.036_bib19","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.neuropharm.2011.06.030","article-title":"Role of neuropeptide Y Y1 and Y2 receptors on behavioral despair in a rat model of depression with co-morbid anxiety","volume":"62","author":"Morales-Medina","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ejphar.2012.10.036_bib20","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/35054063","article-title":"Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor","volume":"409","author":"Naveilhan","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.ejphar.2012.10.036_bib21","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.peptides.2006.09.029","article-title":"Spinal mechanisms of NPY analgesia","volume":"28","author":"Smith","year":"2007","journal-title":"Peptides"},{"key":"10.1016\/j.ejphar.2012.10.036_bib22","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1097\/ALN.0b013e31825a2a2b","article-title":"Gene expression in skin, muscle and dorsal root ganglion after plantar incision in the rat","volume":"117","author":"Spofford","year":"2012","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ejphar.2012.10.036_bib23","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0304-3959(01)00481-X","article-title":"Antihyperalgesic effects of intrathecal neuropeptide Y during inflammation are mediated by Y1 receptors","volume":"96","author":"Taiwo","year":"2002","journal-title":"Pain"},{"key":"10.1016\/j.ejphar.2012.10.036_bib24","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.brainres.2007.04.021","article-title":"Involvement of Y5 receptors in neuropeptide Y agonist-induced analgesic-like effect in the rat hot plate test","volume":"1155","author":"Thomsen","year":"2007","journal-title":"Brain Res."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299912009053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299912009053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,21]],"date-time":"2018-10-21T16:24:40Z","timestamp":1540139080000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299912009053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":23,"journal-issue":{"issue":"1-3","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S0014299912009053"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2012.10.036","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}