{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T22:12:18Z","timestamp":1790201538280,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T00:00:00Z","timestamp":1423008000000},"content-version":"vor","delay-in-days":340,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.ejphar.2014.01.027","type":"journal-article","created":{"date-parts":[[2014,1,29]],"date-time":"2014-01-29T03:30:24Z","timestamp":1390966224000},"page":"16-26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Effects of clonidine in the isolated rat testicular capsule"],"prefix":"10.1016","volume":"726","author":[{"given":"Edilson","family":"Dantas da Silva J\u00fanior","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Palmieri de Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliano","family":"Quintella Dantas Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afonso","family":"Caricati-Neto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aron","family":"Jurkiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neide H.","family":"Jurkiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2014.01.027_bib1","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1474-8673.1982.tb00515.x","article-title":"Analysis of the antagonism by prazosin of noradrenaline and phenylephrine induced contractions of the rat anococcygeus muscle","volume":"2","author":"Adenekan","year":"1982","journal-title":"J. Auton. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib2","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/S0022-3565(24)37640-2","article-title":"Mechanism of relaxant effect of clonidine in isolated bovine tracheal smooth muscle","volume":"286","author":"Arimitsu","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.01.027_bib3","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.1365-3083.1991.tb01537.x","article-title":"Tumour necrosis factor-alpha induces neutrophil-mediated injury of cultured human endothelial cells","volume":"34","author":"von Asmuth","year":"1991","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib4","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1095\/biolreprod.105.044602","article-title":"Smooth muscle and purinergic contraction of the human, rabbit, rat, and mouse testicular capsule","volume":"74","author":"Banks","year":"2006","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ejphar.2014.01.027_bib5","first-page":"23","article-title":"Drug-induced sexual dysfunction and infertility","volume":"3","author":"Beeley","year":"1984","journal-title":"Adverse Drug React. Acute Poisoning Rev."},{"key":"10.1016\/j.ejphar.2014.01.027_bib6","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1530\/jrf.0.0320253","article-title":"The autonomic innervation of the rat testicular capsule","volume":"32","author":"Bell","year":"1973","journal-title":"J. Reprod. Fertil."},{"key":"10.1016\/j.ejphar.2014.01.027_bib7","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S0022-3565(25)30481-7","article-title":"Dissociation constants and relative efficacies of agonists acting on alpha adrenergic receptors in rabbit aorta","volume":"197","author":"Besse","year":"1976","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.01.027_bib8","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1111\/j.1476-5381.1995.tb13326.x","article-title":"Rapid, agonist-induced desensitization of alpha 2-autoreceptors modulating transmitter release","volume":"114","author":"Boehm","year":"1995","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0026-895X(25)08833-9","article-title":"Pharmacological characteristics of alpha 2-adrenergic receptors: comparison of pharmacologically defined subtypes with subtypes identified by molecular cloning","volume":"42","author":"Bylund","year":"1992","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib10","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1590\/S0100-879X2003001100015","article-title":"Effect of cyproterone acetate on alpha1-adrenoceptor subtypes in rat vas deferens","volume":"36","author":"Campos","year":"2003","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.ejphar.2014.01.027_bib11","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1439-0272.1990.tb01974.x","article-title":"Catecholamine distribution in adult rat testis","volume":"22","author":"Campos","year":"1990","journal-title":"Andrologia"},{"key":"10.1016\/j.ejphar.2014.01.027_bib12","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1111\/j.1749-6632.1995.tb32433.x","article-title":"Role of the epithelium in the release of contractile agents from the rat vas deferens by clonidine","volume":"763","author":"Caricati-Neto","year":"1995","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1016\/j.ejphar.2014.01.027_bib13","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1006\/phrs.2001.0857","article-title":"Alpha-adrenoceptor subtypes","volume":"44","author":"Civantos Calzada","year":"2001","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.ejphar.2014.01.027_bib14","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1159\/000124151","article-title":"Evidence for the modulation of sexual behavior by alpha-adrenoceptors in male rats","volume":"41","author":"Clark","year":"1985","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.ejphar.2014.01.027_bib15","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1476-5381.1990.tb14660.x","article-title":"No evidence for differences between pre- and postjunctional alpha 2-adrenoceptors in the periphery","volume":"99","author":"Connaughton","year":"1990","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib16","first-page":"113","article-title":"Idazoxan: a novel pharmacological tool for the study of alpha 2-adrenoceptors","volume":"17","author":"Dabire","year":"1986","journal-title":"J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib17","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/j.1476-5381.1988.tb11669.x","volume":"95","author":"Daly","year":"1988","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib18","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1124\/mol.51.5.711","article-title":"Subtype-specific intracellular trafficking of alpha2-adrenergic receptors","volume":"51","author":"Daunt","year":"1997","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib19","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1530\/jrf.0.0540269","article-title":"Age-related differences in the response of the isolated testicular capsule of the rat to norepinephrine, acetylcholine and prostaglandins","volume":"54","author":"Davis","year":"1978","journal-title":"J. Reprod. Fertil."},{"key":"10.1016\/j.ejphar.2014.01.027_bib20","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1439-0272.1979.tb02238.x","article-title":"Response of the rabbit isolated testicular capsule at hypothermic and hyperthermic temperatures to norepinephrine, acetylcholine and prostaglandin F2 alpha","volume":"11","author":"Davis","year":"1979","journal-title":"Andrologia"},{"key":"10.1016\/j.ejphar.2014.01.027_bib21","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1530\/jrf.0.0190595","article-title":"Response of the isolated testicular capsule of the rat to autonomic drugs","volume":"19","author":"Davis","year":"1969","journal-title":"J. Reprod. Fertil."},{"key":"10.1016\/j.ejphar.2014.01.027_bib22","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/222386a0","article-title":"Response of the testicular capsule to acetylcholine and noradrenaline","volume":"222","author":"Davis","year":"1969","journal-title":"Nature"},{"key":"10.1016\/j.ejphar.2014.01.027_bib23","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1007\/BF00506193","article-title":"Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine","volume":"325","author":"Doxey","year":"1984","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib24","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0014-2999(77)90351-X","article-title":"Pharmacological characterisation of the presynaptic alpha-adrenoceptor in the rat vas deferens","volume":"42","author":"Drew","year":"1977","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib25","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1006\/bbrc.1993.1626","article-title":"Functional alpha 2-adrenergic receptor-Gs coupling undergoes agonist-promoted desensitization in a subtype-selective manner","volume":"193","author":"Eason","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ejphar.2014.01.027_bib26","doi-asserted-by":"crossref","first-page":"15795","DOI":"10.1016\/S0021-9258(19)49605-1","article-title":"Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs","volume":"267","author":"Eason","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2014.01.027_bib27","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/0006-2952(94)00537-V","article-title":"Gi down-regulation and heterologous desensitization in adipocytes after treatment with the alpha 2-agonist UK 14304","volume":"49","author":"Gasic","year":"1995","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib28","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1476-5381.2011.01533.x","article-title":"Are the pharmacology and physiology of alpha(2) adrenoceptors determined by alpha(2)-heteroreceptors and autoreceptors respectively?","volume":"165","author":"Gilsbach","year":"2012","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib29","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1161\/01.HYP.6.4.551","article-title":"Evidence for the existence of vascular alpha 2-adrenergic receptors in humans","volume":"6","author":"Goldberg","year":"1984","journal-title":"Hypertension"},{"key":"10.1016\/j.ejphar.2014.01.027_bib30","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1111\/j.1476-5381.1991.tb12272.x","article-title":"The pharmacology of fluparoxan: a selective alpha 2-adrenoceptor antagonist","volume":"102","author":"Halliday","year":"1991","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib31","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1111\/j.1476-5381.1996.tb16023.x","article-title":"Alpha-adrenoceptor mediated responses of the cauda epididymis of the guinea-pig","volume":"119","author":"Haynes","year":"1996","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib32","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1152\/japplphysiol.00271.2005","article-title":"Clonidine induces nitric oxide- and prostaglandin-mediated vasodilation in healthy human skin","volume":"99","author":"Hermann","year":"2005","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib33","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1476-5381.1976.tb07439.x","article-title":"Dual effect of alpha-adrenoceptor antagonists in rat isolated vas deferens","volume":"56","author":"Jurkiewicz","year":"1976","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib34","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1016\/0024-3205(91)90059-K","article-title":"Release of contractile agents from rat vas deferens by clonidine","volume":"49","author":"Jurkiewicz","year":"1991","journal-title":"Life Sci."},{"key":"10.1016\/j.ejphar.2014.01.027_bib35","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0022-3565(25)31027-X","article-title":"Pharmacodynamic analysis of the rat isolated vas deferens after transplantation to intestinal wall","volume":"203","author":"Jurkiewicz","year":"1977","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.01.027_bib36","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ejphar.2006.05.045","article-title":"Sympathetic neurotransmission in the rat testicular capsule: functional characterization and identification of mRNA encoding alpha1-adrenoceptor subtypes","volume":"543","author":"Jurkiewicz","year":"2006","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib37","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/S0022-3565(25)24233-1","article-title":"Classification of phenoxybenzamine\/prazosin-resistant contractions of rat spleen to norepinephrine by Schild analysis: similarities and differences to postsynaptic alpha-2 adrenoceptors","volume":"244","author":"Kenakin","year":"1988","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.01.027_bib38","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1124\/mol.54.1.44","article-title":"Phosphorylation and functional desensitization of the alpha2A-adrenergic receptor by protein kinase C","volume":"54","author":"Liang","year":"1998","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib39","doi-asserted-by":"crossref","first-page":"4740","DOI":"10.1016\/S0021-9258(18)42894-3","article-title":"Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism","volume":"267","author":"Liggett","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2014.01.027_bib40","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1038\/sj.bjp.0701296","article-title":"Characterization of alpha 2-adrenoceptors mediating contraction of dog saphenous vein: identity with the human alpha 2A subtype","volume":"121","author":"MacLennan","year":"1997","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib41","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S0026-895X(25)09835-9","article-title":"Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes","volume":"46","author":"Minneman","year":"1994","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vph.2004.11.006","article-title":"Clonidine induces rat aorta relaxation by nitric oxide-dependent and -independent mechanisms","volume":"42","author":"Molin","year":"2004","journal-title":"Vasc. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib43","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1124\/pr.55.4.4","article-title":"International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on terms and symbols in quantitative pharmacology","volume":"55","author":"Neubig","year":"2003","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ejphar.2014.01.027_bib44","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0022-3565(25)23638-2","article-title":"Localization and characterization of alpha-2 adrenoceptors in the isolated canine pulmonary vein","volume":"248","author":"Ohlstein","year":"1989","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.01.027_bib45","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1111\/j.1476-5381.1993.tb13507.x","article-title":"Pharmacological characterization of two distinct alpha 1-adrenoceptor subtypes in rabbit thoracic aorta","volume":"108","author":"Oshita","year":"1993","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib46","first-page":"191","article-title":"Studies on relationship between testicular capsule and sperm transport in rat testis","volume":"2","author":"Qin","year":"2000","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.ejphar.2014.01.027_bib47","first-page":"21","article-title":"Effect of testicular capsulotomy on fertility of rats","volume":"3","author":"Qin","year":"2001","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.ejphar.2014.01.027_bib48","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/S0022-3565(25)22237-6","article-title":"Analysis of the presence of postjunctional alpha-2 adrenoceptors in the rat anococcygeus muscle","volume":"250","author":"Ramagopal","year":"1989","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.01.027_bib49","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0031-6997(25)06670-0","article-title":"Structure and function of alpha-adrenoceptors","volume":"43","author":"Ruffolo","year":"1991","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ejphar.2014.01.027_bib50","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1211\/0022357001777577","article-title":"Clonidine attenuates the carbachol-induced contractile and phosphatidylinositol responses of rat trachea","volume":"52","author":"Shibata","year":"2000","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib51","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/sj.ijir.3900393","article-title":"Sexual dysfunction related to antihypertensive agents: results from the animal model","volume":"11","author":"Srilatha","year":"1999","journal-title":"Int. J. Impot. Res."},{"key":"10.1016\/j.ejphar.2014.01.027_bib52","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1038\/sj.bjp.0702598","article-title":"Analysis of alpha 1l-adrenoceptor pharmacology in rat small mesenteric artery","volume":"127","author":"Stam","year":"1999","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib53","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0021-5198(19)43507-5","article-title":"Comparison of agonistic and antagonistic actions of guanabenz and guanfacin on alpha 1 and alpha 2-adrenoceptors in isolated smooth muscles","volume":"43","author":"Takeuchi","year":"1987","journal-title":"Jpn. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib54","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/j.1474-8673.1981.tb00509.x","article-title":"Mini-review. The postsynaptic alpha 2-adrenoreceptor","volume":"1","author":"Timmermans","year":"1981","journal-title":"J. Auton. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib55","first-page":"361","article-title":"The effects of clonidine, guanfacine and phenylephrine on the excitatory and inhibitory responses of the rat anococcygeus muscle","volume":"101","author":"Uzbay","year":"1993","journal-title":"Arch. Int. Physiol. Biol."},{"key":"10.1016\/j.ejphar.2014.01.027_bib56","first-page":"2075","article-title":"Effects of antihypertensive agents on sexual function","volume":"44","author":"Weiss","year":"1991","journal-title":"Am. Fam. Physician"},{"key":"10.1016\/j.ejphar.2014.01.027_bib57","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.ejphar.2008.04.057","article-title":"Potentiation by yohimbine of alpha-adrenoceptor-mediated vasoconstriction in response to clonidine in the rabbit ear vein","volume":"589","author":"Zhao","year":"2008","journal-title":"Eur. J. Pharmacol."}],"updated-by":[{"DOI":"10.1016\/j.ejphar.2014.02.026","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2014,4,5]],"date-time":"2014-04-05T00:00:00Z","timestamp":1396656000000}}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299914000466?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299914000466?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T22:19:27Z","timestamp":1757974767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299914000466"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":57,"alternative-id":["S0014299914000466"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2014.01.027","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.ejphar.2014.02.026","asserted-by":"object"}]},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of clonidine in the isolated rat testicular capsule","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2014.01.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}