{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T06:35:24Z","timestamp":1775370924098,"version":"3.50.1"},"reference-count":75,"publisher":"Elsevier BV","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1016\/j.ejphar.2014.03.047","type":"journal-article","created":{"date-parts":[[2014,4,12]],"date-time":"2014-04-12T20:54:23Z","timestamp":1397336063000},"page":"15-22","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["(S)-amisulpride as a discriminative stimulus in C57BL\/6 mice and its comparison to the stimulus effects of typical and atypical antipsychotics"],"prefix":"10.1016","volume":"734","author":[{"given":"Timothy J.","family":"Donahue","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Todd M.","family":"Hillhouse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin A.","family":"Webster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eliseu O.","family":"De Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph H.","family":"Porter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2014.03.047_bib1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s00213-009-1521-8","article-title":"Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo","volume":"205","author":"Abbas","year":"2009","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib2","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00008877-199203010-00004","article-title":"Sertindole and several antipsychotic-drugs differentially inhibit the discriminative stimulus effects of amphetamine, LSD and St-587 in rats","volume":"3","author":"Arnt","year":"1992","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib3","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0893-133X(97)00112-7","article-title":"Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence","volume":"18","author":"Arnt","year":"1998","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ejphar.2014.03.047_bib5","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0022-3565(25)23493-0","article-title":"Substitution and antagonism in rats trained to discriminate (+)-N-allylnormetazocine from saline","volume":"249","author":"Balster","year":"1989","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib6","doi-asserted-by":"crossref","DOI":"10.1002\/0471142301.ns0805fs25","article-title":"Assessment of learning and memory using the autoshaping of operant responding in mice","volume":"25","author":"Barrett","year":"2003","journal-title":"Curr. Protoc. Neurosci."},{"key":"10.1016\/j.ejphar.2014.03.047_bib7","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1037\/a0014398","article-title":"Medications for stimulant abuse: agonist-based strategies and preclinical evaluation of the mixed-action D2 partial agonist aripiprazole (Abilify)","volume":"16","author":"Bergman","year":"2008","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib8","series-title":"Amisulpride: Summary of Human Pharmacology and Pharmacokinetics","author":"Bianchetti","year":"1995"},{"key":"10.1016\/j.ejphar.2014.03.047_bib9","series-title":"Statistics in Biology","author":"Bliss","year":"1967"},{"key":"10.1016\/j.ejphar.2014.03.047_bib10","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0014-2999(99)00916-4","article-title":"Haloperidol-induced catalepsy is absent in dopamine D(2), but maintained in dopamine D(3) receptor knock-out mice","volume":"391","author":"Boulay","year":"2000","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib11","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/S0028-3908(98)00066-5","article-title":"Discriminative stimulus properties of the putative dopamine D3 receptor agonist, (+)-PD 128907: role of presynaptic dopamine D2 autoreceptors","volume":"37","author":"Bristow","year":"1998","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ejphar.2014.03.047_bib12","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1038\/336783a0","article-title":"Cloning and expression of a rat D2 dopamine receptor cDNA","volume":"336","author":"Bunzow","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.ejphar.2014.03.047_bib13","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1124\/jpet.105.092155","article-title":"Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2\/D3 partial agonist","volume":"315","author":"Burstein","year":"2005","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib14","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0014-2999(01)01484-4","article-title":"(S)-amisulpride binds with high affinity to cloned dopamine D3 and D2 receptors","volume":"432","author":"Castelli","year":"2001","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib15","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/S0022-3565(24)37047-8","article-title":"Characterization of the discriminative stimulus produced by the dopamine antagonist tiapride","volume":"283","author":"Cohen","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib16","doi-asserted-by":"crossref","first-page":"237","DOI":"10.2165\/00023210-199606030-00006","article-title":"Amisulpride: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the management of schizophrenia","volume":"6","author":"Coukell","year":"1996","journal-title":"CNS Drugs"},{"key":"10.1016\/j.ejphar.2014.03.047_bib17","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0006-8993(97)00649-5","article-title":"Effects of amisulpride, an atypical antipsychotic which blocks preferentially presynaptic dopamine autoreceptors, on integrated functional cerebral activity in the rat","volume":"768","author":"Cudennec","year":"1997","journal-title":"Brain Res."},{"key":"10.1016\/j.ejphar.2014.03.047_bib18","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/S0028-3908(03)00040-6","article-title":"Generalization of clozapine as compared to other antipsychotic agents to a discriminative stimulus elicited by the serotonin (5-HT)(2A) antagonist, MDL100,907","volume":"44","author":"Dekeyne","year":"2003","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ejphar.2014.03.047_bib19","first-page":"298","article-title":"Pharmacokinetics and metabolism of amisulpride","volume":"3","author":"Dufour","year":"1988","journal-title":"Ann. Clin. Psychiatry"},{"key":"10.1016\/j.ejphar.2014.03.047_bib20","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/BF00426467","article-title":"Inter-animal olfactory cues in operant drug discrimination procedures in rats","volume":"73","author":"Extance","year":"1981","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib21","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0091-3057(78)90310-6","article-title":"Discriminative stimulus properties of clozapine and chlorpromazine","volume":"8","author":"Goas","year":"1978","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2014.03.047_bib22","series-title":"Biostatistics: An Introductory Text","author":"Goldstein","year":"1964"},{"key":"10.1016\/j.ejphar.2014.03.047_bib23","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1007\/s00213-003-1576-x","article-title":"Characterization of the effects of receptor-selective ligands in rats discriminating the novel antipsychotic quetiapine","volume":"171","author":"Goudie","year":"2004","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib24","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/s002130050527","article-title":"Comparative characterisation of the discriminative stimulus properties of clozapine and other antipsychotics in rats","volume":"135","author":"Goudie","year":"1998","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib25","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/S0022-3565(25)10336-4","article-title":"The discriminative stimulus effects of clozapine in pigeons: involvement of 5-hydroxytryptamine1C and 5-hydroxytryptamine2 receptors","volume":"263","author":"Hoenicke","year":"1992","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib26","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0022-3565(25)24122-2","article-title":"Opioid- and phencyclidine-like discriminative effects of ditolylguanidine, a selective sigma ligand","volume":"248","author":"Holtzman","year":"1989","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib27","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0091-3057(96)00342-5","article-title":"The role of muscarinic cholinergic receptors in the discriminative stimulus properties of clozapine in rats","volume":"57","author":"Kelley","year":"1997","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2014.03.047_bib28","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/BF00429694","article-title":"Discriminative stimulus properties of psychomotor stimulants in the cat","volume":"63","author":"Kilbey","year":"1979","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib29","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/S0022-3565(25)12606-2","article-title":"Pharmacological characterization of the discriminative stimulus effects of cocaine in rhesus monkeys","volume":"254","author":"Kleven","year":"1990","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib30","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/sj.npp.1300027","article-title":"H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs","volume":"28","author":"Kroeze","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ejphar.2014.03.047_bib31","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/S0893-133X(98)00099-2","article-title":"Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes","volume":"20","author":"Lawler","year":"1999","journal-title":"Neuropsychopharmacology"},{"issue":"Suppl.","key":"10.1016\/j.ejphar.2014.03.047_bib32","first-page":"5","article-title":"Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity","volume":"55","author":"Leysen","year":"1994","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.ejphar.2014.03.047_bib33","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1124\/jpet.107.130625","article-title":"Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rhesus monkeys","volume":"324","author":"Li","year":"2008","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib34","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1177\/0269881110385597","article-title":"Discriminative stimulus, subject-rated and cardiovascular effects of cocaine alone and in combination with aripiprazole in humans","volume":"25","author":"Lile","year":"2011","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib35","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1038\/sj.npp.1300803","article-title":"Aripiprazole attenuates the discriminative-stimulus and subject-rated effects of d-amphetamine in humans","volume":"30","author":"Lile","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ejphar.2014.03.047_bib36","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0022-3565(24)37395-1","article-title":"Agonist and inverse agonist activity at the dopamine D3 receptor measured by guanosine 5\u2032-[\u03b3-thio]triphosphate-[35S] binding","volume":"285","author":"Malmberg","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"1-2","key":"10.1016\/j.ejphar.2014.03.047_bib37","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0014-2999(02)01602-3","article-title":"Effect of the amisulpride isomers on rat catalepsy","volume":"444","author":"Marchese","year":"2002","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib38","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0014-2999(02)01990-8","article-title":"Effect of the amisulpride isomers on rat prolactinemia","volume":"448","author":"Marchese","year":"2002","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib39","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s00213-008-1238-0","article-title":"Dopamine D4 receptor involvement in the discriminative stimulus effects in rats of LSD, but not the phenethylamine hallucinogen","volume":"203","author":"Marona-Lewicka","year":"2009","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib40","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1007\/s00213-003-1677-6","article-title":"Aripiprazole (OPC-14597) fully substitutes for the 5-HT1A receptor agonist LY293284 in the drug discrimination assay in rats","volume":"172","author":"Marona-Lewicka","year":"2004","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib42","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/ddr.430180106","article-title":"Discriminative stimulus properties of haloperidol","volume":"18","author":"McElroy","year":"1989","journal-title":"Drug Dev. Res."},{"key":"10.1016\/j.ejphar.2014.03.047_bib43","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1124\/jpet.103.062398","article-title":"S32504, a novel naphtoxazine agonist at dopamine D3\/D2 receptors: I. Cellular, electrophysiological, and neurochemical profile in comparison with ropinirole","volume":"309","author":"Millan","year":"2004","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib44","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s00213-006-0567-0","volume":"191","author":"Millan","year":"2007","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib45","series-title":"Guide for the Care and Use of Laboratory Animals","author":"National Research Council","year":"2011"},{"key":"10.1016\/j.ejphar.2014.03.047_bib46","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0014-2999(85)90753-8","article-title":"Antagonism of the amphetamine cue by both classical and atypical antipsychotic drugs","volume":"111","author":"Nielsen","year":"1985","journal-title":"Eur. J. Pharmacol."},{"issue":"6","key":"10.1016\/j.ejphar.2014.03.047_bib47","doi-asserted-by":"crossref","first-page":"471","DOI":"10.2165\/00023210-199912060-00005","article-title":"Amisulpride: a review of its clinical potential in dysthymia","volume":"12","author":"Noble","year":"1999","journal-title":"CNS Drugs"},{"key":"10.1016\/j.ejphar.2014.03.047_bib48","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0091-3057(94)90464-2","article-title":"Interactions of clozapine with the stimulus effects of DOM and LSD","volume":"49","author":"Palumbo","year":"1994","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2014.03.047_bib49","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0022-3565(24)36394-3","article-title":"Psychopharmacological profile of amisulpride: an antipsychotic drug with presynaptic D2\/D3 dopamine receptor antagonist activity and limbic selectivity","volume":"280","author":"Perrault","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib50","unstructured":"Perrault, G., Schoemaker, H., Midget, J. (2001) Composition of (S) (\u2212)-Amisulpride, U.S. Patent # U.S.6,169,094 B1"},{"key":"10.1016\/j.ejphar.2014.03.047_bib51","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s00213-005-2147-0","article-title":"Serotonin receptor mechanisms mediate the discriminative stimulus properties of the atypical antipsychotic clozapine in C57BL\/6 mice","volume":"180","author":"Philibin","year":"2005","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib52","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/s00213-008-1385-3","article-title":"Further characterization of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in C57BL\/6 mice: role of 5-HT2A serotonergic and a1 adrenergic antagonism","volume":"203","author":"Philibin","year":"2009","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib53","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s00213-008-1308-3","article-title":"Discriminative stimulus properties of atypical and typical antipsychotic drugs: a review of preclinical studies","volume":"203","author":"Porter","year":"2009","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib54","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s002139900366","article-title":"Clozapine discrimination with a low training dose distinguishes atypical from typical antipsychotic drugs in rats","volume":"149","author":"Porter","year":"2000","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib55","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1097\/FBP.0b013e32830cd84e","article-title":"A comparison of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in DBA\/2 and C57BL\/6 inbred mice","volume":"19","author":"Porter","year":"2008","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib56","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.pbb.2003.10.010","article-title":"Discriminative stimulus properties of 1.25 and 5.0mg\/kg doses of clozapine in rats: examination of the role of dopamine, serotonin, and muscarinic receptor mechanisms","volume":"77","author":"Prus","year":"2004","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2014.03.047_bib57","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1016\/S0022-3565(25)11452-3","article-title":"Binding of typical and atypical antipsychotic agents to transiently expressed 5-HT1C receptors","volume":"260","author":"Roth","year":"1992","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib58","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/BF02311185","article-title":"D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs","volume":"120","author":"Roth","year":"1995","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib59","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s002130050255","article-title":"Discriminative stimulus effects of apomorphine and 7-OH-DPAT: a potential role for dopamine D3 receptors","volume":"130","author":"Sanger","year":"1997","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0091-3057(80)90408-6","article-title":"Effect of neuroleptics and tricyclic antidepressants upon d-amphetamine discrimination","volume":"12","author":"Schechter","year":"1980","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2014.03.047_bib61","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0022-3565(24)36395-5","article-title":"Neurochemical characteristics of amisulpride, an atypical dopamine D2\/D3 receptor antagonist with both presynaptic and limbic selectivity","volume":"280","author":"Schoemaker","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib62","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/BF02245606","article-title":"Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding","volume":"124","author":"Schotte","year":"1996","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib63","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0014-2999(94)90643-2","article-title":"Blockade of the discriminative stimulus effects of DOI by MDL 100,907 and the \u2018atypical\u2019 antipsychotics, clozapine and risperidone","volume":"264","author":"Schreiber","year":"1994","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib64","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1097\/JCP.0b013e318221b2db","article-title":"Discriminative-stimulus, subject-rated, and physiological effects of methamphetamine in humans pretreated with aripiprazole","volume":"31","author":"Sevak","year":"2011","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib65","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1038\/sj.npp.1300203","article-title":"Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology","volume":"28","author":"Shapiro","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ejphar.2014.03.047_bib66","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1037\/1064-1297.10.4.376","article-title":"Discriminative stimulus properties in rats of the novel antipsychotic quetiapine","volume":"10","author":"Smith","year":"2002","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib67","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0014-2999(87)90426-2","article-title":"Discriminative stimulus properties of a sigma receptor agonist in the rat: role of monoamine systems","volume":"141","author":"Steinfels","year":"1987","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib68","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1037\/1064-1297.14.4.413","article-title":"Aripiprazole as a potential pharmacotherapy for stimulant dependence: human laboratory studies with d-amphetamine","volume":"14","author":"Stoops","year":"2006","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib69","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0091-3057(99)00146-X","article-title":"Inability of antipsychotics to antagonize the cueing properties of cocaine in rats","volume":"64","author":"van Campenhout","year":"1999","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2014.03.047_bib70","first-page":"273","article-title":"An automated learning and memory model in mice: pharmacological and behavioral evaluation of an autoshaped response","volume":"9","author":"Vanover","year":"1998","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib71","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/S0022-3565(25)38398-9","article-title":"Evaluation of the reinforcing and discriminative stimulus effects of cocaine in combination with (+)-AJ76 or clozapine","volume":"266","author":"Vanover","year":"1993","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.ejphar.2014.03.047_bib72","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0014-2999(86)90016-6","article-title":"Dopamine D2 receptor mediation of the discriminative stimulus properties of LY 171555 (quinpirole)","volume":"132","author":"Weathersby","year":"1986","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2014.03.047_bib73","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/j.ejmech.2007.02.005","article-title":"Synthesis of bridged piperazines with sigma receptor affinity","volume":"42","author":"Weigl","year":"2007","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ejphar.2014.03.047_bib74","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/BF00429199","article-title":"A neuropharmacological analysis of the discriminative stimulus properties of fenfluramine","volume":"73","author":"White","year":"1981","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib75","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/BF00430748","article-title":"Training dose as a factor in LSD-saline discrimination","volume":"76","author":"White","year":"1982","journal-title":"Psychopharmacology (Berlin)"},{"key":"10.1016\/j.ejphar.2014.03.047_bib76","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/0091-3057(92)90433-G","article-title":"Serotonergic drugs do not substitute for clozapine in clozapine-trained rats in a two-lever drug discrimination procedure","volume":"43","author":"Wiley","year":"1992","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2014.03.047_bib77","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1016\/0024-3205(82)90446-5","article-title":"Comparative discriminative stimulus effects of 5-methoxy-N,N-dimethyltryptamine and LSD","volume":"30","author":"Young","year":"1982","journal-title":"Life Sci."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299914002623?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299914002623?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T10:36:12Z","timestamp":1746182172000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299914002623"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":75,"alternative-id":["S0014299914002623"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2014.03.047","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"(S)-amisulpride as a discriminative stimulus in C57BL\/6 mice and its comparison to the stimulus effects of typical and atypical antipsychotics","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2014.03.047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}