{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T10:46:31Z","timestamp":1778323591186,"version":"3.51.4"},"reference-count":86,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Tehran University of Medical Sciences","award":["92-02-169-23147"],"award-info":[{"award-number":["92-02-169-23147"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.ejphar.2016.09.017","type":"journal-article","created":{"date-parts":[[2016,9,13]],"date-time":"2016-09-13T01:18:02Z","timestamp":1473729482000},"page":"369-376","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["The effect of nitrazepam on depression and curiosity in behavioral tests in mice: The role of potassium channels"],"prefix":"10.1016","volume":"791","author":[{"given":"Vahid","family":"Nikoui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sattar","family":"Ostadhadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pardis","family":"Azhand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samira","family":"Zolfaghari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shayan","family":"Amiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehrdad","family":"Foroohandeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manijeh","family":"Motevalian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali Mohammad","family":"Sharifi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azam","family":"Bakhtiarian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2016.09.017_bib1","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1007\/BF00173583","article-title":"GABA-mediated modification of despair behavior in mice","volume":"339","author":"Alev","year":"1989","journal-title":"Naunyn Schmiedeberg's Arch. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib2","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1126\/science.2305257","article-title":"Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels","volume":"247","author":"Amoroso","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.ejphar.2016.09.017_bib3","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1370\/afm.349","article-title":"Efficacy and tolerability of tricyclic antidepressants and SSRIs compared with placebo for treatment of depression in primary care: a meta-analysis","volume":"3","author":"Arroll","year":"2005","journal-title":"Ann. Fam. Med."},{"key":"10.1016\/j.ejphar.2016.09.017_bib4","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0091-3057(01)00599-8","article-title":"Intra-and interstrain differences in models of \u201cbehavioral despair\u201d","volume":"70","author":"Bai","year":"2001","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2016.09.017_bib5","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1192\/bjp.bp.109.076448","article-title":"Efficacy of antidepressants and benzodiazepines in minor depression: systematic review and meta-analysis","volume":"198","author":"Barbui","year":"2011","journal-title":"Br. J. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib6","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1038\/nrn1846","article-title":"New approaches to antidepressant drug discovery: beyond monoamines","volume":"7","author":"Berton","year":"2006","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ejphar.2016.09.017_bib7","first-page":"405","article-title":"Some doubts about the basic concept of hole-board test","volume":"4","author":"Bilkei-Gorzo","year":"1995","journal-title":"Neurobiology"},{"key":"10.1016\/j.ejphar.2016.09.017_bib8","doi-asserted-by":"crossref","first-page":"1581","DOI":"10.1016\/j.bcp.2004.07.023","article-title":"\u03b3-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions","volume":"68","author":"Boehm","year":"2004","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib9","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1023\/A:1026545316455","article-title":"Habituation of activity in an open field: a survey of inbred strains and F1 hybrids","volume":"30","author":"Bolivar","year":"2000","journal-title":"Behav. Genet."},{"key":"10.1016\/j.ejphar.2016.09.017_bib10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF01243369","article-title":"Regional GABA concentration and [3H]-diazepam binding in rat brain following repeated electroconvulsive shock","volume":"56","author":"Bowdler","year":"1983","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.ejphar.2016.09.017_bib11","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/sj.mp.4001362","article-title":"GABAergic dysfunction in mood disorders","volume":"8","author":"Brambilla","year":"2003","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0006-3223(03)00473-6","article-title":"Association of depression with medical illness: does cortisol play a role?","volume":"55","author":"Brown","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib13","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.ejphar.2007.08.010","article-title":"Role of different types of potassium channels in the antidepressant-like effect of agmatine in the mouse forced swimming test","volume":"575","author":"Budni","year":"2007","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib14","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1177\/0269881111424456","article-title":"Involvement of PI3K, GSK-3\u03b2 and PPAR\u03b3 in the antidepressant-like effect of folic acid in the forced swimming test in mice","volume":"26","author":"Budni","year":"2012","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib15","first-page":"9","article-title":"Epidemiology of depression throughout the female life cycle","volume":"63","author":"Burt","year":"2002","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib16","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.2337\/db06-1102","article-title":"ATP-sensitive K+ channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia","volume":"56","author":"Chan","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.ejphar.2016.09.017_bib17","doi-asserted-by":"crossref","DOI":"10.1176\/ajp.2006.163.12.2141","article-title":"Changes in the prevalence of major depression and comorbid substance use disorders in the United States between 1991\u20131992 and 2001\u20132002","author":"Compton","year":"2006","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib18","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s002130050327","article-title":"Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies","volume":"132","author":"Crawley","year":"1997","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ejphar.2016.09.017_bib19","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0165-6147(02)02017-5","article-title":"Assessing antidepressant activity in rodents: recent developments and future needs","volume":"23","author":"Cryan","year":"2002","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.ejphar.2016.09.017_bib20","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0006-8993(01)02987-0","article-title":"Adaptation and habituation to an open field and responses to various stressful events in animals with neonatal lesions in the amygdala or ventral hippocampus","volume":"918","author":"Daenen","year":"2001","journal-title":"Brain Res."},{"key":"10.1016\/j.ejphar.2016.09.017_bib21","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1089\/jmf.2014.0074","article-title":"Evidence for the involvement of potassium channel inhibition in the antidepressant-like effects of hesperidin in the tail suspension test in mice","volume":"18","author":"Donato","year":"2015","journal-title":"J. Med. Food"},{"key":"10.1016\/j.ejphar.2016.09.017_bib22","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3109\/13651500903447810","article-title":"Usage of benzodiazepines: a review","volume":"14","author":"Donoghue","year":"2010","journal-title":"Int. J. Psychiatry Clin. Pract."},{"key":"10.1016\/j.ejphar.2016.09.017_bib23","first-page":"170","article-title":"Adinazolam-a new antidepressant: findings of a placebo-controlled, double-blind study in outpatients with major depression","volume":"7","author":"Dunner","year":"1987","journal-title":"J. Clin. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib24","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1016\/0024-3205(87)90283-9","article-title":"Evidence that muscimol acts in the forced swimming test by activating the rat dopaminergic system","volume":"41","author":"Evangelista","year":"1987","journal-title":"Life Sci."},{"key":"10.1016\/j.ejphar.2016.09.017_bib25","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/0014-2999(92)90123-L","article-title":"Antidepressant and anxiolytic effects of alprazolam versus the conventional. antidepressant desipramine and the anxiolytic diazepam in the forced swim test in rats","volume":"214","author":"Flugy","year":"1992","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib26","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1038\/sj.bjp.0702467","article-title":"Effect of potassium channel modulators in mouse forced swimming test","volume":"126","author":"Galeotti","year":"1999","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib27","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/0091-3057(95)02226-0","article-title":"Additive effects of glyburide and antidepressants in the forced swimming test: evidence for the involvement of potassium channel blockade","volume":"54","author":"Guo","year":"1996","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2016.09.017_bib28","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ejphar.2014.03.053","article-title":"Opioid\/NMDA receptors blockade reverses the depressant-like behavior of foot shock stress in the mouse forced swimming test","volume":"735","author":"Haj-Mirzaian","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib29","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1139\/cjpp-2015-0429","article-title":"Fluoxetine reverses the behavioral despair induced by neurogenic stress in mice: role of N-methyl-d-aspartate and opioid receptors","volume":"94","author":"Haj-Mirzaian","year":"2016","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib30","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ejphar.2016.03.034","article-title":"Involvement of nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of tropisetron and ondansetron in mice forced swimming test and tail suspension test","volume":"780","author":"Haj-Mirzaian","year":"2016","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib31","doi-asserted-by":"crossref","first-page":"3551","DOI":"10.1007\/s00213-015-4004-0","article-title":"Evidence for the involvement of NMDA receptors in the antidepressant-like effect of nicotine in mouse forced swimming and tail suspension tests","volume":"232","author":"Haj-Mirzaian","year":"2015","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ejphar.2016.09.017_bib32","doi-asserted-by":"crossref","first-page":"e39084","DOI":"10.1371\/journal.pone.0039084","article-title":"Ubiquitin-specific peptidase 46 (Usp46) regulates mouse immobile behavior in the tail suspension test through the GABAergic system","volume":"7","author":"Imai","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.ejphar.2016.09.017_bib33","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ejphar.2009.04.041","article-title":"Involvement of different types of potassium channels in the antidepressant-like effect of tramadol in the mouse forced swimming test","volume":"613","author":"Jesse","year":"2009","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib34","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.neulet.2010.12.053","article-title":"Role of different types of potassium channels and peroxisome proliferator-activated receptors \u03b3 in the antidepressant-like activity of bis selenide in the mouse tail suspension test","volume":"490","author":"Jesse","year":"2011","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ejphar.2016.09.017_bib35","article-title":"A comparison of the safety and efficacy of alprazolam versus other agents in the treatment of anxiety, panic, and depression: a review of the literature","author":"Jonas","year":"1993","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib36","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1016\/j.pnpbp.2006.12.018","article-title":"The inhibition of different types of potassium channels underlies the antidepressant-like effect of adenosine in the mouse forced swimming test","volume":"31","author":"Kaster","year":"2007","journal-title":"Prog. Neuro Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib37","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/0031-9384(94)90293-3","article-title":"Antidepressants suppress bulbectomy-induced augmentation of voluntary alcohol consumption in C57Bl\/6j but not in DBA\/2j mice","volume":"56","author":"Katkov","year":"1994","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.ejphar.2016.09.017_bib38","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1600-0447.1988.tb05082.x","article-title":"Treatment of depression with clonazepam","volume":"77","author":"Kishimoto","year":"1988","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.ejphar.2016.09.017_bib39","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/s00259-009-1292-9","article-title":"Reduced parahippocampal and lateral temporal GABAA-[11C] flumazenil binding in major depression: preliminary results","volume":"37","author":"Klumpers","year":"2010","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.ejphar.2016.09.017_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pbb.2015.11.009","article-title":"Involvement of N-methyl-d-aspartate receptors in the antidepressant-like effect of 5-hydroxytryptamine 3 antagonists in mouse forced swimming test and tail suspension test","volume":"141","author":"Kordjazy","year":"2016","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2016.09.017_bib41","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1111\/j.1471-4159.1983.tb08078.x","article-title":"Desmethylimipramine enhances the release of endogenous GABA and other neuro transmitter amino acids from the rat thalamus","volume":"40","author":"Korf","year":"1983","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ejphar.2016.09.017_bib42","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0301-0082(02)00013-8","article-title":"Drug interactions at GABA A receptors","volume":"67","author":"Korpi","year":"2002","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib43","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1126\/science.1184334","article-title":"Channel-mediated tonic GABA release from glia","volume":"330","author":"Lee","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.ejphar.2016.09.017_bib44","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/00008877-199711000-00010","article-title":"The forced swimming test as a model for core and component behavioral effects of antidepressant drugs","volume":"8","author":"Lucki","year":"1997","journal-title":"Behav. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib45","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.eplepsyres.2009.03.027","article-title":"Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: a comparative study","volume":"85","author":"Luszczki","year":"2009","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.ejphar.2016.09.017_bib46","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/gps.642","article-title":"The prevalence of major depression or dysthymia among aged medicare fee-for\u2010service beneficiaries","volume":"17","author":"McCall","year":"2002","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib47","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.neuropharm.2011.08.040","article-title":"The GABA system in anxiety and depression and its therapeutic potential","volume":"62","author":"M\u00f6hler","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ejphar.2016.09.017_bib48","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ejphar.2012.04.041","article-title":"Involvement of different types of potassium channels in the antidepressant-like effect of ascorbic acid in the mouse tail suspension test","volume":"687","author":"Moretti","year":"2012","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib49","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/hup.1015","article-title":"Clonazepam as a therapeutic adjunct to improve the management of depression: a brief review","volume":"24","author":"Morishita","year":"2009","journal-title":"Hum. Psychopharmacol.: Clin. Exp."},{"key":"10.1016\/j.ejphar.2016.09.017_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharep.2016.07.006","article-title":"Possible involvement of ATP-sensitive potassium channels in the antidepressant-like effect of baclofen in mouse forced swimming test","author":"Nazari","year":"2016","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.ejphar.2016.09.017_bib51","first-page":"22","article-title":"Neurobiological mechanisms in generalized anxiety disorder","volume":"62","author":"Nutt","year":"2001","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib52","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1016\/j.bcp.2004.07.026","article-title":"Fishing for allosteric sites on GABA A receptors","volume":"68","author":"Olsen","year":"2004","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib53","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.biopha.2016.04.026","article-title":"Antidepressant effect of pramipexole in mice forced swimming test: a cross talk between dopamine receptor and NMDA\/nitric oxide\/cGMP pathway","volume":"81","author":"Ostadhadi","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.ejphar.2016.09.017_bib54","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/1440-1681.12518","article-title":"Involvement of opioid system in antidepressant-like effect of the cannabinoid CB1 receptor inverse agonist AM\u2010251 after physical stress in mice","volume":"43","author":"Ostadhadi","year":"2016","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib55","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00210-015-1203-5","article-title":"Involvement of NO\/cGMP pathway in the antidepressant-like effect of gabapentin in mouse forced swimming test","volume":"389","author":"Ostadhadi","year":"2016","journal-title":"Naunyn Schmiedeberg's Arch. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib56","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.brainresbull.2016.03.004","article-title":"Involvement of NMDA receptors and l-arginine\/nitric oxide\/cyclic guanosine monophosphate pathway in the antidepressant-like effects of topiramate in mice forced swimming test","volume":"122","author":"Ostadhadi","year":"2016","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.ejphar.2016.09.017_bib57","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/j.biopha.2016.05.035","article-title":"Pharmacological evidence for the involvement of the NMDA receptor and nitric oxide pathway in the antidepressant-like effect of lamotrigine in the mouse forced swimming test","volume":"82","author":"Ostadhadi","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.ejphar.2016.09.017_bib58","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0006-2952(75)90313-5","article-title":"Effect of desipramine and pargyline on brain gamma-aminobutyric acid","volume":"24","author":"Patel","year":"1975","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib59","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/0091-3057(87)90447-3","article-title":"Noradrenergic rather than GABAergic processes as the common mediation of the antidepressant profile of GABA agonists and imipramine-like drugs in animals","volume":"28","author":"Poncelet","year":"1987","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2016.09.017_bib60","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1111\/j.1471-4159.1969.tb08978.x","article-title":"Some effects of monoamine oxidase inhibitors on the metabolism of \u03b3-aminobutyric acid in rat brain","volume":"16","author":"Popov","year":"1969","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ejphar.2016.09.017_bib61","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/266730a0","article-title":"Depression: a new animal model sensitive to antidepressant treatments","volume":"266","author":"Porsolt","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.ejphar.2016.09.017_bib62","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1038\/sj.npp.1301234","article-title":"GABAergic neurons immunoreactive for calcium binding proteins are reduced in the prefrontal cortex in major depression","volume":"32","author":"Rajkowska","year":"2007","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.ejphar.2016.09.017_bib63","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/S0006-3223(99)00041-4","article-title":"Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression","volume":"45","author":"Rajkowska","year":"1999","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib64","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1017\/S1092852900011573","article-title":"Augmentation of antidepressant pharmacotherapy: a preclinical approach using the mouse forced swimming test","volume":"4","author":"Redrobe","year":"1999","journal-title":"CNS Spectr."},{"key":"10.1016\/j.ejphar.2016.09.017_bib65","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0166-4328(03)00034-2","article-title":"Antidepressant-like effects in various mice strains in the tail suspension test","volume":"143","author":"Ripoll","year":"2003","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ejphar.2016.09.017_bib66","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1177\/0269881106064203","article-title":"Allopregnanolone reduces immobility in the forced swimming test and increases the firing rate of lateral septal neurons through actions on the GABAA receptor in the rat","volume":"21","author":"Rodr\u00ecguez-Landa","year":"2007","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib67","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/j.1875-9114.1984.tb03311.x","article-title":"Alprazolam in bipolar-I depressions","volume":"4","author":"Rush","year":"1984","journal-title":"Pharmacother.: J. Hum. Pharmacol. Drug Ther."},{"key":"10.1016\/j.ejphar.2016.09.017_bib68","first-page":"14","article-title":"Impairment of GABAergic transmission in depression: new insights from neuroimaging studies","author":"Sanacora","year":"2000","journal-title":"Crit. Rev. Neurobiol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib69","doi-asserted-by":"crossref","DOI":"10.1176\/appi.ajp.159.4.663","article-title":"Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors","author":"Sanacora","year":"2002","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib70","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1176\/appi.ajp.160.3.577","article-title":"Increased cortical GABA concentrations in depressed patients receiving ECT","volume":"160","author":"Sanacora","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib71","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1001\/archpsyc.56.11.1043","article-title":"Reduced cortical \u03b3-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy","volume":"56","author":"Sanacora","year":"1999","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.ejphar.2016.09.017_bib72","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1111\/j.1471-4159.1971.tb00213.x","article-title":"Elevation of brain GABA by pargyline: a possible mechanism for protection against oxygen toxicity","volume":"18","author":"Schatz","year":"1971","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ejphar.2016.09.017_bib73","first-page":"22","article-title":"Role of ATP-sensitive potassium channels in the clonic seizure threshold induced by pentylenetetrazole in mice with diabetes type I","volume":"20","author":"Shafaroodi","year":"2010","journal-title":"Med. Sci. J. Islam. Azad Univ. Tehran Med. Branch"},{"key":"10.1016\/j.ejphar.2016.09.017_bib74","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.eplepsyres.2016.01.003","article-title":"A role for ATP-sensitive potassium channels in the anticonvulsant effects of triamterene in mice","volume":"121","author":"Shafaroodi","year":"2016","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.ejphar.2016.09.017_bib75","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.eplepsyres.2007.04.005","article-title":"Role of ATP-sensitive potassium channels in the biphasic effects of morphine on pentylenetetrazole-induced seizure threshold in mice","volume":"75","author":"Shafaroodi","year":"2007","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.ejphar.2016.09.017_bib76","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0031-6997(25)06840-1","article-title":"Structure and pharmacology of gamma-aminobutyric acid A receptor subtypes","volume":"47","author":"Sieghart","year":"1995","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ejphar.2016.09.017_bib77","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0197-0186(99)00045-5","article-title":"Structure and subunit composition of GABA A receptors","volume":"34","author":"Sieghart","year":"1999","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.ejphar.2016.09.017_bib78","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0166-4328(03)00093-7","article-title":"MHC-congenic mice (C57BL\/6J and B6-H-2K) show differences in speed but not accuracy in learning the Hebb\u2013Williams Maze","volume":"144","author":"Stanford","year":"2003","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ejphar.2016.09.017_bib79","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/BF00428203","article-title":"The tail suspension test: a new method for screening antidepressants in mice","volume":"85","author":"Steru","year":"1985","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ejphar.2016.09.017_bib80","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/BF00215493","article-title":"Strain differences in response to drugs in the tail suspension test for antidepressant activity","volume":"92","author":"Van der Heyden","year":"1987","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.ejphar.2016.09.017_bib81","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ejphar.2007.08.045","article-title":"The antidepressant effects of curcumin in the forced swimming test involve 5-HT 1 and 5-HT 2 receptors","volume":"578","author":"Wang","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib82","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0163-7258(02)00201-2","article-title":"K+ channels as therapeutic drug targets","volume":"94","author":"Wickenden","year":"2002","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.ejphar.2016.09.017_bib83","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1111\/j.2042-7158.2010.01132.x","article-title":"Evidence of the involvement of K+ channels and PPAR\u03b3 receptors in the antidepressant-like activity of diphenyl diselenide in mice","volume":"62","author":"Wilhelm","year":"2010","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.ejphar.2016.09.017_bib84","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jad.2006.08.017","article-title":"Pharmacological treatment of acute mania in psychiatric in-patients between 1994 and 2004","volume":"99","author":"Wolfsperger","year":"2007","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.ejphar.2016.09.017_bib85","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.neuroscience.2005.06.067","article-title":"In vivo evidence for reduced cortical glutamate\u2013glutamine cycling in rats treated with the antidepressant\/antipanic drug phenelzine","volume":"135","author":"Yang","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.ejphar.2016.09.017_bib86","first-page":"143","article-title":"[Pharmacological profiles of benzodiazepinergic hypnotics and correlations with receptor subtypes]","volume":"25","author":"Yasui","year":"2005","journal-title":"Nihon Shinkei Seishin Yakurigaku Zasshi=Jpn. J. Psychopharmacol."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299916305878?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299916305878?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T18:20:17Z","timestamp":1749579617000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299916305878"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":86,"alternative-id":["S0014299916305878"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2016.09.017","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of nitrazepam on depression and curiosity in behavioral tests in mice: The role of potassium channels","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2016.09.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}