{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T14:41:50Z","timestamp":1771339310624,"version":"3.50.1"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"NIH-NCI","award":["CA207287"],"award-info":[{"award-number":["CA207287"]}]},{"name":"WesternU intramural startup fund","award":["12550-1395"],"award-info":[{"award-number":["12550-1395"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.ejphar.2018.06.035","type":"journal-article","created":{"date-parts":[[2018,6,30]],"date-time":"2018-06-30T09:06:22Z","timestamp":1530349582000},"page":"157-168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Intracellular emetic signaling evoked by the L-type Ca2+ channel agonist FPL64176 in the least shrew (Cryptotis parva)"],"prefix":"10.1016","volume":"834","author":[{"given":"Weixia","family":"Zhong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seetha","family":"Chebolu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nissar A.","family":"Darmani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2018.06.035_bib1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.ejphar.2013.08.047","article-title":"The role of vagal neurocircuits in the regulation of nausea and vomiting","volume":"722","author":"Babic","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib2","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.neuroscience.2012.08.016","article-title":"Inhibition of endoplasmic reticulum Ca2+ ATPase in preB\u00f6tzinger complex of neonatal rat does not affect respiratory rhythm generation","volume":"224","author":"Beltran-Parrazal","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.ejphar.2018.06.035_bib3","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.ceca.2009.03.018","article-title":"Homeostatic and stimulus-induced coupling of the L-type Ca2+ channel to the ryanodine receptor in the hippocampal neuron in slices","volume":"46","author":"Berrout","year":"2009","journal-title":"Cell Calcium"},{"key":"10.1016\/j.ejphar.2018.06.035_bib4","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/hipo.10042","article-title":"Distribution and morphology of serotonin-immunoreactive axons in the hippocampal region of the New Zealand white rabbit. I. Area dentata and hippocampus","volume":"13","author":"Bjarkam","year":"2003","journal-title":"Hippocampus"},{"key":"10.1016\/j.ejphar.2018.06.035_bib5","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1146\/annurev.cellbio.16.1.521","article-title":"Structure and regulation of voltage-gated Ca2+ channels","volume":"16","author":"Catterall","year":"2000","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib6","doi-asserted-by":"crossref","first-page":"39695","DOI":"10.1074\/jbc.M102334200","article-title":"Calcium entry through L-type calcium channels causes mitochondrial disruption and chromaffin cell death","volume":"276","author":"Cano-Abad","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2018.06.035_bib7","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.ejphar.2009.11.030","article-title":"Pranlukast prevents cysteinyl leukotriene-induced emesis in the least shrew (Cryptotis parva)","volume":"628","author":"Chebolu","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib8","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1007\/s007020050118","article-title":"Serotonin 5-HT3 receptor antagonists prevent cisplatin-induced emesis in Cryptotis parva: a new experimental model of emesis","volume":"105","author":"Darmani","year":"1998","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.ejphar.2018.06.035_bib9","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ejphar.2012.09.008","article-title":"Cisplatin causes over-expression of tachykinin NK(1) receptors and increases ERK1\/2- and PKA- phosphorylation during peak immediate- and delayed-phase emesis in the least shrew (Cryptotis parva) brainstem","volume":"698","author":"Darmani","year":"2013","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib10","doi-asserted-by":"crossref","first-page":"3158","DOI":"10.1021\/cr900117p","article-title":"Evidence for a re-evaluation of the neurochemical and anatomical bases of chemotherapy-induced vomiting","volume":"109","author":"Darmani","year":"2009","journal-title":"Chem. Rev."},{"key":"10.1016\/j.ejphar.2018.06.035_bib11","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brainres.2008.03.077","article-title":"Utilization of the least shrew as a rapid and selective screening model for the antiemetic potential and brain penetration of substance P and NK1 receptor antagonists","volume":"1214","author":"Darmani","year":"2008","journal-title":"Brain Res."},{"key":"10.1016\/j.ejphar.2018.06.035_bib12","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.pbb.2015.02.010","article-title":"Differential and additive suppressive effects of 5-HT3 (palonosetron)- and NK1 (netupitant)-receptor antagonists on cisplatin-induced vomiting and ERK1\/2, PKA and PKC activation","volume":"131","author":"Darmani","year":"2015","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2018.06.035_bib13","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.ejphar.2013.08.052","article-title":"Broad-spectrum antiemetic potential of the L-type calcium channel antagonist nifedipine and evidence for its additive antiemetic interaction with the 5-HT(3) receptor antagonist palonosetron in the least shrew (Cryptotis parva)","volume":"722","author":"Darmani","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib14","doi-asserted-by":"crossref","first-page":"C1097","DOI":"10.1152\/ajpcell.2001.280.5.C1097","article-title":"Protein kinase C-mediated desensitization of the neurokinin 1 receptor","volume":"280","author":"D\u00e9ry","year":"2001","journal-title":"Am. J. Physiol. Cell. Physiol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib15","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.steroids.2014.07.009","article-title":"Targeting thapsigargin towards tumors","volume":"97","author":"Doan","year":"2015","journal-title":"Steroids"},{"key":"10.1016\/j.ejphar.2018.06.035_bib16","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/S0006-3495(03)74481-6","article-title":"SERCA pump optimizes Ca2+ release by a mechanism independent of store filling in smooth muscle cells","volume":"85","author":"G\u00f3mez-Viquez","year":"2003","journal-title":"Biophys. J."},{"key":"10.1016\/j.ejphar.2018.06.035_bib17","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/cne.902390204","article-title":"Observations on the afferent and efferent organization of the vagus nerve and the innervation of the stomach in the squirrel monkey","volume":"239","author":"Gwyn","year":"1985","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib18","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/jnr.20894","article-title":"Serotonin induces the increase in intracellular Ca2+ that enhances neurite outgrowth in PC12 cells via activation of 5-HT3 receptors and voltage-gated calcium channels","volume":"84","author":"Homma","year":"2006","journal-title":"J. Neurosci. Res."},{"issue":"Suppl. 8A","key":"10.1016\/j.ejphar.2018.06.035_bib19","doi-asserted-by":"crossref","first-page":"106S","DOI":"10.1016\/S0002-9343(01)00849-X","article-title":"Central neurocircuitry associated with emesis","volume":"111","author":"Hornby","year":"2001","journal-title":"Am. J. Med."},{"issue":"277","key":"10.1016\/j.ejphar.2018.06.035_bib20","doi-asserted-by":"crossref","first-page":"47366","DOI":"10.1074\/jbc.M208284200","article-title":"U0126 and PD98059, specific inhibitors of MEK, accelerate differentiation of RAW264.7 cells into osteoclast-like cells","volume":"2002","author":"Hotokezaka","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"8","key":"10.1016\/j.ejphar.2018.06.035_bib21","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1021\/acschemneuro.6b00417","article-title":"Serotonin in space: understanding single fibers","volume":"17","author":"Janu\u0161onis","year":"2017","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.ejphar.2018.06.035_bib22","first-page":"29","article-title":"Phosphatidylinositol 3-kinase inhibitor (LY294002) induces apoptosis of human nasopharyngealcarcinoma in vitro and in vivo","volume":"22","author":"Jiang","year":"2010","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.ejphar.2018.06.035_bib23","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1159\/000075666","article-title":"Expression of c-FOS in the brain after activation of L-type calcium channels","volume":"25","author":"Jinnah","year":"2003","journal-title":"Dev. Neurosci."},{"key":"10.1016\/j.ejphar.2018.06.035_bib24","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/1531-8257(200005)15:3<542::AID-MDS1019>3.0.CO;2-2","article-title":"Calcium channel agonists and dystonia in the mouse","volume":"15","author":"Jinnah","year":"2000","journal-title":"Mov. Disord."},{"key":"10.1016\/j.ejphar.2018.06.035_bib25","doi-asserted-by":"crossref","first-page":"15228","DOI":"10.1073\/pnas.96.26.15228","article-title":"Calcium channel activation and self-biting in mice","volume":"96","author":"Jinnah","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ejphar.2018.06.035_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ejphar.2013.10.014","article-title":"Looking beyond 5-HT(3) receptors: a review of the wider role of serotonin in the pharmacology of nausea and vomiting","volume":"722","author":"Johnston","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib27","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1007\/s00520-015-2990-4","article-title":"Defining the efficacy of neurokinin-1 receptor antagonists in controlling chemotherapy-induced nausea and vomiting in different emetogenic settings-a meta-analysis","volume":"24","author":"Jordan","year":"2016","journal-title":"Support. Care Cancer"},{"key":"10.1016\/j.ejphar.2018.06.035_bib28","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1161\/01.RES.87.2.106","article-title":"Transmission of information from cardiac dihydropyridine receptor to ryanodine receptor: evidence from BayK 8644 effects on resting Ca(2+) sparks","volume":"87","author":"Katoh","year":"2000","journal-title":"Circ. Res."},{"key":"10.1016\/j.ejphar.2018.06.035_bib29","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/cne.902060202","article-title":"The ultrastructure of the subnucleus gelatinosus of the nucleus of the tractus solitarius in the cat","volume":"206","author":"Leslie","year":"1982","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib30","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.hrthm.2013.10.006","article-title":"Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca2+ spark characteristics: direct evidence of functional Ca2+-induced Ca2+ release","volume":"11","author":"Li","year":"2014","journal-title":"Heart Rhythm."},{"key":"10.1016\/j.ejphar.2018.06.035_bib31","doi-asserted-by":"crossref","first-page":"564","DOI":"10.3389\/fnins.2016.00564","article-title":"Mechanosensory signaling in enterochromaffin cells and 5-HT release: potential implications for gut inflammation","volume":"10","author":"Linan-Rico","year":"2016","journal-title":"Front Neurosci."},{"key":"10.1016\/j.ejphar.2018.06.035_bib32","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/S0016-5085(99)70286-6","article-title":"L-Type calcium channels in enterochromaffin cells from guinea pig and human duodenal crypts: an in situ study","volume":"117","author":"Lomax","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ejphar.2018.06.035_bib33","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1006\/frne.1994.1012","article-title":"The area postrema and vomiting","volume":"15","author":"Miller","year":"1994","journal-title":"Front Neuroendocrinol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib34","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0014-2999(01)01297-3","article-title":"Effects of CP-99, 994, a tachykinin NK(1) receptor antagonist,on abdominal afferent vagal activity in ferrets: evidence for involvement of NK(1) and 5-HT(3) receptors","volume":"428","author":"Minami","year":"2001","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib35","first-page":"R1725","article-title":"Duodenal nutrient infusions differentially affect sham feeding and Fos expression in rat brain stem","volume":"274","author":"Phifer","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib36","doi-asserted-by":"crossref","first-page":"3060","DOI":"10.1152\/jn.00755.2007","article-title":"Subdivision-specific responses of neurons in the nucleus of the tractus solitarius to activation of mu-opioid receptors in the rat","volume":"98","author":"Poole","year":"2007","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib37","doi-asserted-by":"crossref","first-page":"5959","DOI":"10.1113\/jphysiol.2013.259796","article-title":"Identification of unique release kinetics of serotonin from guinea-pig and human enterochromaffin cells","volume":"591","author":"Raghupathi","year":"2013","journal-title":"J. Physiol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib38","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.pbb.2009.08.010","article-title":"Receptor-selective agonists induce emesis and Fos expression in the brain and enteric nervous system of the least shrew (Cryptotis parva)","volume":"94","author":"Ray","year":"2009","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2018.06.035_bib39","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1037\/a0015733","article-title":"Ablation of least shrew central neurokinin NK1 receptors reduces GR73632-induced vomiting","volume":"123","author":"Ray","year":"2009","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.ejphar.2018.06.035_bib40","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.bbr.2008.07.028","article-title":"Delta 9-tetrahydrocannabinol suppresses vomiting behavior and Fos expression in both acute and delayed phases of cisplatin-induced emesis in the least shrew","volume":"196","author":"Ray","year":"2009","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.ejphar.2018.06.035_bib41","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s00441-013-1643-5","article-title":"Distribution of voltage-dependent and intracellular Ca2+ channels in submucosal neurons from rat distal colon","volume":"353","author":"Rehn","year":"2013","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.ejphar.2018.06.035_bib42","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1089\/scd.2008.0289","article-title":"Intracellular Ca2+ regulation during neuronal differentiation of murine embryonal carcinoma and mesenchymal stem cells","volume":"19","author":"Resende","year":"2010","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.ejphar.2018.06.035_bib43","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.ejphar.2013.08.049","article-title":"Molecular mechanisms of 5-HT(3) and NK(1) receptor antagonists in prevention of emesis","volume":"722","author":"Rojas","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib44","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1523\/JNEUROSCI.02-11-01660.1982","article-title":"Immunocytochemical analysis of serotonergic axons in laminae I and II of the lumbar spinal cord of the cat","volume":"2","author":"Ruda","year":"1982","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ejphar.2018.06.035_bib45","doi-asserted-by":"crossref","first-page":"9534","DOI":"10.1523\/JNEUROSCI.5199-08.2009","article-title":"L-type voltage-dependent calcium channel antagonists impair perirhinal long-term recognition memory and plasticity processes","volume":"29","author":"Seoane","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ejphar.2018.06.035_bib46","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ejphar.2012.05.037","article-title":"Inhibition of substance P-mediated responses in NG108-15 cells by netupitant and palonosetron exhibit synergistic effects","volume":"689","author":"Stathis","year":"2012","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib47","doi-asserted-by":"crossref","first-page":"34150","DOI":"10.1074\/jbc.M303584200","article-title":"Modulation of 5-HT3 receptor-mediated response and trafficking by activation of protein kinase C","volume":"278","author":"Sun","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2018.06.035_bib48","doi-asserted-by":"crossref","first-page":"a004010","DOI":"10.1101\/cshperspect.a004010","article-title":"IP(3) receptors: toward understanding their activation","volume":"2","author":"Taylor","year":"2010","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib49","doi-asserted-by":"crossref","first-page":"2637","DOI":"10.1007\/s00221-014-4017-7","article-title":"Netupitant and palonosetron trigger NK1 receptor internalization in NG108-15 cells","volume":"232","author":"Thomas","year":"2014","journal-title":"Exp. Brain Res."},{"key":"10.1016\/j.ejphar.2018.06.035_bib50","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/nrgastro.2016.76","article-title":"Vagal neurocircuitry and its influence on gastric motility","volume":"13","author":"Travagli","year":"2016","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib51","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.lfs.2015.02.014","article-title":"Characterization of lysophosphatidylcholine-induced changes of intracellular calcium in Drosophila S2 cells","volume":"131","author":"Wang","year":"2015","journal-title":"Life Sci."},{"key":"10.1016\/j.ejphar.2018.06.035_bib52","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.ejps.2011.10.007","article-title":"Lysophosphatidylcholine induces Ca(2+) mobilization in Jurkat human T lymphocytes and CTLL-2 mouse T lymphocytes by different pathways","volume":"44","author":"Wang","year":"2011","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.ejphar.2018.06.035_bib53","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1124\/pr.114.009654","article-title":"The physiology, pathology, and pharmacology of voltage-gated calcium channels and their future therapeutic potential","volume":"67","author":"Zamponi","year":"2015","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ejphar.2018.06.035_bib54","first-page":"R1104","article-title":"Effect of brain stem NMDA-receptor blockade by MK-801 on behavioral and Fos responses to vagal satiety signals","volume":"277","author":"Zheng","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.ejphar.2018.06.035_bib55","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.autneu.2016.07.006","article-title":"Ca2+ signaling and emesis: recent progress and new perspectives","volume":"202","author":"Zhong","year":"2017","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.ejphar.2018.06.035_bib56","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.pbb.2014.03.005","article-title":"Broad-spectrum antiemetic efficacy of the L-type calcium channel blocker amlodipine in the least shrew (Cryptotis parva)","volume":"120","author":"Zhong","year":"2014","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.ejphar.2018.06.035_bib57","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.neuropharm.2015.11.023","article-title":"Thapsigargin-induced activation of Ca(2+)-CaMKII-ERK in brainstem contributes to substance P release and induction of emesis in the least shrew","volume":"103","author":"Zhong","year":"2016","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ejphar.2018.06.035_bib58","doi-asserted-by":"crossref","first-page":"e104718","DOI":"10.1371\/journal.pone.0104718","article-title":"Serotonin 5-HT3 receptor-mediated vomiting occurs via the activation of Ca2+\/CaMKII-dependent ERK1\/2 signaling in the least shrew (Cryptotis parva)","volume":"9","author":"Zhong","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ejphar.2018.06.035_bib59","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/emboj.2010.279","article-title":"Ryanodine receptor-2 upregulation and nicotine-mediated plasticity","volume":"30","author":"Ziviani","year":"2011","journal-title":"EMBO J."},{"key":"10.1016\/j.ejphar.2018.06.035_bib60","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0014-5793(83)80508-0","article-title":"Calcium-dependent protein phosphorylation and dephosphorylation in intact brain neurons in culture","volume":"156","author":"Zurgil","year":"1983","journal-title":"FEBS Lett."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299918303674?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299918303674?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T22:47:27Z","timestamp":1561070847000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299918303674"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":60,"alternative-id":["S0014299918303674"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2018.06.035","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intracellular emetic signaling evoked by the L-type Ca2+ channel agonist FPL64176 in the least shrew (Cryptotis parva)","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2018.06.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}