{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T05:35:38Z","timestamp":1773207338212,"version":"3.50.1"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2021-R1A4A1031574"],"award-info":[{"award-number":["2021-R1A4A1031574"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2021-R1F1A1045544"],"award-info":[{"award-number":["2021-R1F1A1045544"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.ejphar.2022.175305","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T11:27:21Z","timestamp":1664450841000},"page":"175305","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The antidiabetic drug teneligliptin induces vasodilation via activation of PKG, Kv channels, and SERCA pumps in aortic smooth muscle"],"prefix":"10.1016","volume":"935","author":[{"given":"Hongliang","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Ryeol","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minju","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaehee","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryeon","family":"Heo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minji","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seo-Yeong","family":"Mun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenwen","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mi Seon","family":"Seo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun-Taek","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Hee","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanjoo","family":"Chun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5868-3797","authenticated-orcid":false,"given":"Won Sun","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2022.175305_bib1","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1161\/CIRCULATIONAHA.118.034731","article-title":"Polycystin-1 assembles with Kv channels to govern cardiomyocyte repolarization and contractility","volume":"140","author":"Altamirano","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.ejphar.2022.175305_bib2","doi-asserted-by":"crossref","first-page":"e273","DOI":"10.1161\/ATVBAHA.119.313492","article-title":"Myocardin-dependent Kv1.5 channel expression prevents phenotypic modulation of human vessels in organ culture","volume":"39","author":"Ar\u00e9valo-Mart\u00ednez","year":"2019","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ejphar.2022.175305_bib3","doi-asserted-by":"crossref","first-page":"814","DOI":"10.3390\/ijms19030814","article-title":"Effects of nitric oxide on voltage-gated K\u207a currents in human cardiac fibroblasts through the protein kinase G and protein kinase A pathways but not through S-nitrosylation","volume":"19","author":"Bae","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ejphar.2022.175305_bib4","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s40265-019-01086-0","article-title":"The unique pharmacological and pharmacokinetic profile of teneligliptin: implications for clinical practice","volume":"79","author":"Ceriello","year":"2019","journal-title":"Drugs"},{"key":"10.1016\/j.ejphar.2022.175305_bib5","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.ceca.2017.07.001","article-title":"SERCA control of cell death and survival","volume":"69","author":"Chemaly","year":"2018","journal-title":"Cell Calcium"},{"key":"10.1016\/j.ejphar.2022.175305_bib6","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s13300-019-00742-8","article-title":"Vildagliptin versus \u03b1-glucosidase inhibitor as add-on to metformin for type 2 diabetes: subgroup Analysis of the China prospective diabetes study","volume":"11","author":"Chen","year":"2020","journal-title":"Diabetes Ther"},{"key":"10.1016\/j.ejphar.2022.175305_bib7","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1161\/01.STR.0000116867.28589.3A","article-title":"Influence of gender on K+-induced cerebral vasodilatation","volume":"35","author":"Chrissobolis","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.ejphar.2022.175305_bib8","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s12325-016-0434-2","article-title":"Fixed-dose combination of canagliflozin and metformin for the treatment of type 2 diabetes: an overview","volume":"34","author":"Davidson","year":"2017","journal-title":"Adv. Ther."},{"key":"10.1016\/j.ejphar.2022.175305_bib9","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1007\/s00125-019-4959-1","article-title":"New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism","volume":"62","author":"Eid","year":"2019","journal-title":"Diabetologia"},{"key":"10.1016\/j.ejphar.2022.175305_bib10","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.2174\/138945012802002348","article-title":"Cardiovascular therapeutics targets on the NO-sGC-cGMP signaling pathway: a critical overview","volume":"13","author":"Evora","year":"2012","journal-title":"Curr. Drug Targets"},{"key":"10.1016\/j.ejphar.2022.175305_bib11","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/FJC.0000000000000346","article-title":"Endothelium-dependent hyperpolarization and endothelial dysfunction","volume":"67","author":"F\u00e9l\u00e9tou","year":"2016","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.ejphar.2022.175305_bib12","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.pharmthera.2016.05.002","article-title":"Novel treatment strategies for smooth muscle disorders: targeting Kv7 potassium channels","volume":"165","author":"Haick","year":"2016","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.ejphar.2022.175305_bib13","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/cpdd.29","article-title":"Pharmacokinetics of teneligliptin in subjects with renal impairment","volume":"2","author":"Halabi","year":"2013","journal-title":"Clin. Pharmacol. Drug Dev."},{"key":"10.1016\/j.ejphar.2022.175305_bib14","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1093\/cvr\/cvu163","article-title":"Delayed phospholamban phosphorylation in post-conditioned heart favours Ca2+ normalization and contributes to protection","volume":"103","author":"Inserte","year":"2014","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ejphar.2022.175305_bib15","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1177\/1060028013504076","article-title":"Alogliptin: a new dipeptidyl peptidase-4 inhibitor for type 2 diabetes mellitus","volume":"47","author":"Jarvis","year":"2013","journal-title":"Ann. Pharmacother."},{"key":"10.1016\/j.ejphar.2022.175305_bib16","doi-asserted-by":"crossref","first-page":"142","DOI":"10.3389\/fphar.2019.00142","article-title":"Vildagliptin reduces stenosis of injured carotid artery in diabetic mouse through inhibiting vascular smooth muscle cell proliferation via ER stress\/NF-\u03baB pathway","volume":"10","author":"Ji","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ejphar.2022.175305_bib17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.yjmcc.2016.06.066","article-title":"A dipeptidyl peptidase-4 inhibitor ameliorates hypertensive cardiac remodeling via angiotensin-II\/sodium-proton pump exchanger-1 axis","volume":"98","author":"Kawase","year":"2016","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.ejphar.2022.175305_bib18","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/dom.13566","article-title":"Teneligliptin versus sitagliptin in Korean patients with type 2 diabetes inadequately controlled with metformin and glimepiride: a randomized, double-blind, non-inferiority trial","volume":"21","author":"Kim","year":"2019","journal-title":"Diabetes Obes. Metabol."},{"key":"10.1016\/j.ejphar.2022.175305_bib19","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2147\/DMSO.S35682","article-title":"Teneligliptin: a DPP-4 inhibitor for the treatment of type 2 diabetes","volume":"6","author":"Kishimoto","year":"2013","journal-title":"Diabetes Metab. Syndr. Obes."},{"key":"10.1016\/j.ejphar.2022.175305_bib20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.pbiomolbio.2009.10.001","article-title":"Pathophysiology of voltage-gated K+ channels in vascular smooth muscle cells: modulation by protein kinases","volume":"103","author":"Ko","year":"2010","journal-title":"Prog. Biophys. Mol. Biol."},{"key":"10.1016\/j.ejphar.2022.175305_bib21","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.ijcard.2016.02.146","article-title":"Effect of dipeptidyl peptidase-4 inhibitors on heart failure: a meta-analysis of randomized clinical trials","volume":"211","author":"Kongwatcharapong","year":"2016","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ejphar.2022.175305_bib22","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.3390\/ijms21051616","article-title":"Integration of Rap1 and calcium signaling","volume":"21","author":"Kosuru","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ejphar.2022.175305_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.taap.2019.114799","article-title":"Dipeptidyl peptidase-4 inhibitor sitagliptin induces vasorelaxation via the activation of Kv channels and PKA","volume":"384","author":"Li","year":"2019","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.ejphar.2022.175305_bib24","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3389\/fphar.2018.00449","article-title":"Efficacy and safety of teneligliptin in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials","volume":"9","author":"Li","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ejphar.2022.175305_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/cells9091956","article-title":"Clinical importance of the human umbilical artery potassium channels","volume":"9","author":"Lorigo","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.ejphar.2022.175305_bib26","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1016\/S0024-3205(02)01922-7","article-title":"Contributions of Kv1.2, Kv1.5 and Kv2.1 subunits to the native delayed rectifier K(+) current in rat mesenteric artery smooth muscle cells","volume":"71","author":"Lu","year":"2002","journal-title":"Life Sci."},{"key":"10.1016\/j.ejphar.2022.175305_bib27","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1124\/mol.115.101758","article-title":"Kv7.5 potassium channel subunits are the primary targets for PKA-dependent enhancement of vascular smooth muscle Kv7 currents","volume":"89","author":"Mani","year":"2016","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ejphar.2022.175305_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2020.107499","article-title":"Ion channels as effectors of cyclic nucleotide pathways: functional relevance for arterial tone regulation","volume":"209","author":"Manoury","year":"2020","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.ejphar.2022.175305_bib29","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1113\/JP276054","article-title":"miR-1 is increased in pulmonary hypertension and downregulates Kv1.5 channels in rat pulmonary arteries","volume":"597","author":"Mondejar-Parre\u00f1o","year":"2019","journal-title":"J. Physiol."},{"issue":"3","key":"10.1016\/j.ejphar.2022.175305_bib31","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1517\/14656566.2015.1000301","article-title":"Teneligliptin : expectations for its pleiotropic action","volume":"16","author":"Morishita","year":"2015","journal-title":"Expet Opin. Pharmacother."},{"key":"10.1016\/j.ejphar.2022.175305_bib32","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.bbrc.2013.03.010","article-title":"A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site","volume":"434","author":"Nabeno","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ejphar.2022.175305_bib33","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1161\/CIRCRESAHA.116.309491","article-title":"Contribution of KV1.5 channel to hydrogen peroxide-induced human arteriolar dilation and its modulation by coronary artery disease","volume":"120","author":"Nishijima","year":"2017","journal-title":"Circ. Res."},{"key":"10.1016\/j.ejphar.2022.175305_bib34","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1161\/CIRCRESAHA.115.306642","article-title":"Requisite role of Kv1.5 channels in coronary metabolic dilation","volume":"117","author":"Ohanyan","year":"2015","journal-title":"Circ. Res."},{"key":"10.1016\/j.ejphar.2022.175305_bib35","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1161\/HYPERTENSIONAHA.119.14400","volume":"75","author":"Okabe","year":"2020","journal-title":"Hypertension"},{"key":"10.1016\/j.ejphar.2022.175305_bib36","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s11255-013-0552-6","article-title":"Safety and efficacy of teneligliptin: a novel DPP-4 inhibitor for hemodialysis patients with type 2 diabetes","volume":"46","author":"Otsuki","year":"2014","journal-title":"Int. Urol. Nephrol."},{"key":"10.1016\/j.ejphar.2022.175305_bib37","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0301-0082(98)00009-4","article-title":"Cyclic nucleotide crosstalk and the regulation of cerebral vasodilation","volume":"56","author":"Pelligrino","year":"1998","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.ejphar.2022.175305_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1530\/JOE-12-0521","article-title":"DPP-4 inhibitors improve cognition and brain mitochondrial function of insulin-resistant rats","volume":"218","author":"Pintana","year":"2013","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.ejphar.2022.175305_bib39","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1016\/j.clinthera.2011.09.028","article-title":"Tolerability of dipeptidyl peptidase-4 inhibitors: a review","volume":"33","author":"Richard","year":"2011","journal-title":"Clin. Therapeut."},{"key":"10.1016\/j.ejphar.2022.175305_bib40","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1177\/2042098618769568","article-title":"The pale evidence for treatment of iron-deficiency anaemia in older people","volume":"9","author":"Soiza","year":"2018","journal-title":"Ther. Adv. Drug Saf."},{"key":"10.1016\/j.ejphar.2022.175305_bib41","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1007\/s10072-020-04681-2","article-title":"Efficacy and tolerability of DPP4 inhibitor, teneligliptin, on autonomic and peripheral neuropathy in type 2 diabetes: an open label, pilot study","volume":"42","author":"Syngle","year":"2021","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.ejphar.2022.175305_bib42","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/j.2040-4603.2017.tb00747.x","article-title":"Smooth muscle ion channels and regulation of vascular tone in resistance arteries and arterioles","volume":"7","author":"Tykocki","year":"2017","journal-title":"Compr. Physiol."},{"key":"10.1016\/j.ejphar.2022.175305_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109565","article-title":"Research progress on Traditional Chinese Medicine syndromes of diabetes mellitus","volume":"121","author":"Wang","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.ejphar.2022.175305_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2020.101617","article-title":"Antispasmodic drug drofenine as an inhibitor of Kv2.1 channel ameliorates peripheral neuropathy in diabetic mice","volume":"23","author":"Xu","year":"2020","journal-title":"iScience"},{"key":"10.1016\/j.ejphar.2022.175305_bib45","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/dom.12344","article-title":"Ghrelin signalling in \u03b2-cells regulates insulin secretion and blood glucose","volume":"16","author":"Yada","year":"2014","journal-title":"Diabetes Obes. Metabol."},{"key":"10.1016\/j.ejphar.2022.175305_bib46","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.vph.2006.08.002","article-title":"Nitric oxide and the endothelium: history and impact on cardiovascular disease","volume":"45","author":"Yetik-Anacak","year":"2006","journal-title":"Vasc. Pharmacol."},{"key":"10.1016\/j.ejphar.2022.175305_bib47","doi-asserted-by":"crossref","first-page":"10489","DOI":"10.1073\/pnas.93.19.10489","article-title":"NO hyperpolarizes pulmonary artery smooth muscle cells and decreases the intracellular Ca2+ concentration by activating voltage-gated K+ channels","volume":"93","author":"Yuan","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ejphar.2022.175305_bib48","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s00395-021-00859-7","article-title":"Adenosine and adenosine receptor-mediated action in coronary microcirculation","volume":"116","author":"Zhang","year":"2021","journal-title":"Basic Res. Cardiol."},{"key":"10.1016\/j.ejphar.2022.175305_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.103061","article-title":"SP6616 as a Kv2.1 inhibitor efficiently ameliorates peripheral neuropathy in diabetic mice","volume":"61","author":"Zhu","year":"2020","journal-title":"EBioMedicine"}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299922005660?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299922005660?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T23:07:33Z","timestamp":1757977653000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299922005660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":48,"alternative-id":["S0014299922005660"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2022.175305","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The antidiabetic drug teneligliptin induces vasodilation via activation of PKG, Kv channels, and SERCA pumps in aortic smooth muscle","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2022.175305","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"175305"}}