{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T17:13:46Z","timestamp":1790097226889,"version":"4.0.1"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,24]],"date-time":"2023-02-24T00:00:00Z","timestamp":1677196800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007833","name":"Hamad Medical Corporation","doi-asserted-by":"publisher","award":["MRC-01-20-951"],"award-info":[{"award-number":["MRC-01-20-951"]}],"id":[{"id":"10.13039\/100007833","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.ejphar.2023.175612","type":"journal-article","created":{"date-parts":[[2023,2,21]],"date-time":"2023-02-21T21:29:51Z","timestamp":1677014991000},"page":"175612","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)"],"prefix":"10.1016","volume":"945","author":[{"given":"Varghese P.","family":"Inchakalody","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shereena P.","family":"Hydrose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roopesh","family":"Krishnankutty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maysaloun","family":"Merhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lubna","family":"Therachiyil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varun","family":"Sasidharan Nair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asma A.","family":"Elashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul Q.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Taleb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afsheen","family":"Raza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeenath Safira K.M.","family":"Yoosuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Queenie","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lobna","family":"Al-Zaidan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarra","family":"Mestiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nassiba","family":"Taib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takwa","family":"Bedhiafi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dina","family":"Moustafa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laila","family":"Assami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karama Makni","family":"Maalej","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eyad","family":"Elkord","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahab","family":"Uddin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ussama","family":"Al Homsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5526-7496","authenticated-orcid":false,"given":"Said","family":"Dermime","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2023.175612_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027339","article-title":"Fascin is a key regulator of breast cancer invasion that acts via the modification of metastasis-associated molecules","volume":"6","author":"Al-Alwan","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ejphar.2023.175612_bib2","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/j.leukres.2010.02.004","article-title":"The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer\/testis antigens in myeloid leukemia cells","volume":"34","author":"Almstedt","year":"2010","journal-title":"Leuk. Res."},{"key":"10.1016\/j.ejphar.2023.175612_bib3","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.humpath.2013.05.029","article-title":"Expression of New York esophageal squamous cell carcinoma-1 in primary and metastatic melanoma","volume":"45","author":"Aung","year":"2014","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.ejphar.2023.175612_bib4","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nrclinonc.2013.42","article-title":"The future of epigenetic therapy in solid tumours - lessons from the past","volume":"10","author":"Azad","year":"2013","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.ejphar.2023.175612_bib5","doi-asserted-by":"crossref","DOI":"10.1186\/s12885-019-5665-6","article-title":"Major vault protein suppresses lung cancer cell proliferation by inhibiting STAT3 signaling pathway","volume":"19","author":"Bai","year":"2019","journal-title":"BMC Cancer"},{"key":"10.1016\/j.ejphar.2023.175612_bib6","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1007\/s00262-011-1037-z","article-title":"MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells to facilitate cytotoxic T lymphocyte-mediated tumor cell killing","volume":"60","author":"Bao","year":"2011","journal-title":"Cancer Immunol. Immunother."},{"key":"10.1016\/j.ejphar.2023.175612_bib7","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1158\/1078-0432.CCR-05-1544","article-title":"Tumor antigen expression in melanoma varies according to antigen and stage","volume":"12","author":"Barrow","year":"2006","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.ejphar.2023.175612_bib8","author":"Berr"},{"key":"10.1016\/j.ejphar.2023.175612_bib9","doi-asserted-by":"crossref","DOI":"10.1186\/s12958-021-00790-5","article-title":"5-aza-2\u2032-deoxycitidine inhibits cell proliferation, extracellular matrix formation and Wnt\/\u03b2-catenin pathway in human uterine leiomyomas","volume":"19","author":"Carbajo-Garc\u00eda","year":"2021","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.ejphar.2023.175612_bib10","doi-asserted-by":"crossref","first-page":"2415","DOI":"10.1056\/NEJMoa1613493","article-title":"First-line nivolumab in stage IV or recurrent non-small-cell lung cancer","volume":"376","author":"Carbone","year":"2017","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ejphar.2023.175612_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.molonc.2012.11.004","article-title":"HDAC1-mSin3a-NCOR1, Dnmt3b-HDAC1-Egr1 and Dnmt1-PCNA-UHRF1-G9a regulate the NY-ESO1 gene expression Pierre-Francois","volume":"7","author":"Cartron","year":"2013","journal-title":"Molecular Oncology"},{"key":"10.1016\/j.ejphar.2023.175612_bib12","doi-asserted-by":"crossref","first-page":"9517","DOI":"10.2147\/CMAR.S229726","article-title":"5-Aza-CdR regulates RASSF1A by inhibiting DNMT1 to affect colon cancer cell proliferation, migration and apoptosis","volume":"11","author":"Chen","year":"2019","journal-title":"Cancer Manag. Res."},{"key":"10.1016\/j.ejphar.2023.175612_bib13","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1073\/pnas.94.5.1914","article-title":"A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening","volume":"94","author":"Chen","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ejphar.2023.175612_bib14","doi-asserted-by":"crossref","first-page":"74036","DOI":"10.18632\/oncotarget.18198","article-title":"Promoter hypomethylation of NY-ESO-1, association with clinicopathological features and PD-L1 expression in non-small cell lung cancer","volume":"8","author":"Ch\u00fceh","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.ejphar.2023.175612_bib15","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1021\/pr101065j","article-title":"Andromeda: a peptide search engine integrated into the MaxQuant environment","volume":"10","author":"Cox","year":"2011","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.ejphar.2023.175612_bib16","doi-asserted-by":"crossref","first-page":"10903","DOI":"10.2147\/OTT.S217767","article-title":"DNA methyltransferase inhibitors: catalysts for antitumour immune responses","volume":"12","author":"Dan","year":"2019","journal-title":"OncoTargets Ther."},{"key":"10.1016\/j.ejphar.2023.175612_bib17","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1080\/01926230701320337","article-title":"Apoptosis: a review of programmed cell death","volume":"35","author":"Elmore","year":"2007","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.ejphar.2023.175612_bib18","first-page":"3","article-title":"A novel human-derived antibody against NY-ESO-1 improves the efficacy of chemotherapy","volume":"13","author":"Gupta","year":"2013","journal-title":"Cancer Immun."},{"key":"10.1016\/j.ejphar.2023.175612_bib19","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1016\/j.biochi.2012.05.029","article-title":"Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2\u2032-deoxycytidine in anaplastic large cell lymphoma","volume":"94","author":"Hassler","year":"2012","journal-title":"Biochimie"},{"key":"10.1016\/j.ejphar.2023.175612_bib20","first-page":"445","article-title":"Expression of peroxiredoxin 1 and 4 promotes human lung cancer malignancy","volume":"4","author":"Jiang","year":"2014","journal-title":"American journal of cancer research"},{"key":"10.1016\/j.ejphar.2023.175612_bib21","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1158\/2159-8290.CD-11-0214","article-title":"Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer","volume":"1","author":"Juergens","year":"2011","journal-title":"Cancer Discov."},{"key":"10.1016\/j.ejphar.2023.175612_bib22","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1399-0004.2011.01809.x","article-title":"Epigenetic modifications in cancer","volume":"81","author":"Kanwal","year":"2012","journal-title":"Clin. Genet."},{"key":"10.1016\/j.ejphar.2023.175612_bib23","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2019.00954","article-title":"Targeting the complement pathway as a therapeutic strategy in lung cancer","volume":"10","author":"Kleczko","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ejphar.2023.175612_bib24","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.pan.2012.05.012","article-title":"The actin binding protein destrin is associated with growth and perineural invasion of pancreatic cancer","volume":"12","author":"Klose","year":"2012","journal-title":"Pancreatology"},{"key":"10.1016\/j.ejphar.2023.175612_bib25","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1093\/bioinformatics\/18.11.1427","article-title":"MethPrimer: designing primers for methylation PCRs","volume":"18","author":"Li","year":"2002","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ejphar.2023.175612_bib26","doi-asserted-by":"crossref","first-page":"811","DOI":"10.3892\/mmr.2014.2230","article-title":"Complement component 3 is a prognostic factor of non-small cell lung cancer","volume":"10","author":"Lin","year":"2014","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.ejphar.2023.175612_bib27","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.omto.2020.12.014","article-title":"Fascin actin-bundling protein 1 in human cancer: promising biomarker or therapeutic target?","volume":"20","author":"Liu","year":"2021","journal-title":"Molecular Therapy - Oncolytics"},{"key":"10.1016\/j.ejphar.2023.175612_bib28","doi-asserted-by":"crossref","first-page":"545","DOI":"10.3892\/or.2012.1838","article-title":"5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status","volume":"28","author":"Liu","year":"2012","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.ejphar.2023.175612_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12943-020-01197-3","article-title":"Epigenetic regulation in human cancer: the potential role of epi-drug in cancer therapy","volume":"19","author":"Lu","year":"2020","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.ejphar.2023.175612_bib30","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.crvi.2005.05.002","article-title":"Regulation of Bcl-2 proteins and of the permeability of the outer mitochondrial membrane","volume":"328","author":"Lucken-Ardjomande","year":"2005","journal-title":"Comptes Rendus Biol."},{"key":"10.1016\/j.ejphar.2023.175612_bib31","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2019.00489","article-title":"DNA methylation readers and cancer: mechanistic and therapeutic applications","volume":"9","author":"Mahmood","year":"2019","journal-title":"Front. Oncol."},{"key":"10.1016\/j.ejphar.2023.175612_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2021.107889","article-title":"A novel era of cancer\/testis antigen in cancer immunotherapy","volume":"98","author":"Meng","year":"2021","journal-title":"Int. Immunopharm."},{"key":"10.1016\/j.ejphar.2023.175612_bib33","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.3389\/fimmu.2018.01769","article-title":"Squamous cell carcinomas of the head and neck cancer response to programmed cell death protein-1 targeting and differential expression of immunological markers: a case report","volume":"9","author":"Merhi","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ejphar.2023.175612_bib34","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2020-001278","article-title":"Persistent anti-NY-ESO-1-specific T cells and expression of differential biomarkers in a patient with metastatic gastric cancer benefiting from combined radioimmunotherapy treatment: a case report","volume":"8","author":"Merhi","year":"2020","journal-title":"J Immunother Cancer"},{"key":"10.1016\/j.ejphar.2023.175612_bib35","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1002\/ijc.23407","article-title":"The DNA demethylating agent 5-aza-2\u2032-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma","volume":"122","author":"Natsume","year":"2008","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.ejphar.2023.175612_bib36","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1186\/s13148-015-0157-2","article-title":"Epigenetic treatment of solid tumours: a review of clinical trials","volume":"7","author":"Nervi","year":"2015","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.ejphar.2023.175612_bib37","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3892\/mco.2017.1129","article-title":"The role of peroxiredoxins in cancer","volume":"6","author":"Nicolussi","year":"2017","journal-title":"Molecular and Clinical Oncology"},{"key":"10.1016\/j.ejphar.2023.175612_bib38","doi-asserted-by":"crossref","DOI":"10.3390\/jcm9051362","article-title":"Immune checkpoint inhibitors for lung cancer treatment: a review","volume":"9","author":"Onoi","year":"2020","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.ejphar.2023.175612_bib39","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.1002\/pmic.201400515","article-title":"FunRich: an open access standalone functional enrichment and interaction network analysis tool","volume":"15","author":"Pathan","year":"2015","journal-title":"Proteomics"},{"key":"10.1016\/j.ejphar.2023.175612_bib40","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1038\/nprot.2007.261","article-title":"Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips","volume":"2","author":"Rappsilber","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.ejphar.2023.175612_bib41","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s12967-020-02306-y","article-title":"Unleashing the immune response to NY-ESO-1 cancer testis antigen as a potential target for cancer immunotherapy","volume":"18","author":"Raza","year":"2020","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.ejphar.2023.175612_bib42","doi-asserted-by":"crossref","DOI":"10.3390\/antib9040057","article-title":"Complement system: promoter or suppressor of cancer progression?","volume":"9","author":"Revel","year":"2020","journal-title":"Antibodies"},{"key":"10.1016\/j.ejphar.2023.175612_bib43","first-page":"1","article-title":"DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer","volume":"10","author":"Sasidharan Nair","year":"2018","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.ejphar.2023.175612_bib44","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1007\/s00018-011-0735-1","article-title":"Vimentin in cancer and its potential as a molecular target for cancer therapy","volume":"68","author":"Satelli","year":"2011","journal-title":"Cell. Mol. Life Sci. : CM"},{"key":"10.1016\/j.ejphar.2023.175612_bib45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fonc.2017.00060","article-title":"The mitochondrial voltage-dependent anion channel 1, Ca2+ transport, apoptosis, and their regulation","volume":"7","author":"Shoshan-Barmatz","year":"2017","journal-title":"Front. Oncol."},{"key":"10.1016\/j.ejphar.2023.175612_bib46","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1158\/0008-5472.CAN-03-3070","article-title":"NY-ESO-1 expression and immunogenicity in malignant and benign breast tumors","volume":"64","author":"Sugita","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.ejphar.2023.175612_bib47","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA A Cancer J. Clin."},{"key":"10.1016\/j.ejphar.2023.175612_bib48","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0140-6736(21)00312-3","article-title":"Lung cancer","volume":"398","author":"Thai","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.ejphar.2023.175612_bib49","doi-asserted-by":"crossref","first-page":"947","DOI":"10.3389\/fimmu.2018.00947","article-title":"NY-ESO-1 based immunotherapy of cancer: current perspectives","volume":"9","author":"Thomas","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ejphar.2023.175612_bib50","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1038\/nprot.2016.136","article-title":"The MaxQuant computational platform for mass spectrometry-based shotgun proteomics","volume":"11","author":"Tyanova","year":"2016","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.ejphar.2023.175612_bib51","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1158\/2159-8290.CD-14-1326","article-title":"Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis","volume":"5","author":"Van Rechem","year":"2015","journal-title":"Cancer Discov."},{"key":"10.1016\/j.ejphar.2023.175612_bib52","article-title":"Expression of the cancer\/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM)--correlation with prognostic factors","volume":"7","author":"Velazquez","year":"2007","journal-title":"Cancer Immun."},{"key":"10.1016\/j.ejphar.2023.175612_bib53","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1097\/JTO.0b013e318031cd78","article-title":"Apoptotic signaling pathways in lung cancer","volume":"2","author":"Viktorsson","year":"2007","journal-title":"J. Thorac. Oncol."},{"key":"10.1016\/j.ejphar.2023.175612_bib54","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1146\/annurev-genet-102108-134850","article-title":"The role of mitochondria in apoptosis","volume":"43","author":"Wang","year":"2009","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/j.ejphar.2023.175612_bib55","first-page":"129","article-title":"Inhibition of Stat3 activation and tumor growth suppression of non-small cell lung cancer by G-quartet oligonucleotides","volume":"31","author":"Weerasinghe","year":"2007","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.ejphar.2023.175612_bib56","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.tips.2016.11.009","article-title":"Heat shock proteins and cancer","volume":"38","author":"Wu","year":"2017","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.ejphar.2023.175612_bib57","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6692811","article-title":"Actin-binding proteins as potential biomarkers for chronic inflammation-induced cancer diagnosis and therapy","volume":"2021","author":"Zhang","year":"2021","journal-title":"Anal. Cell Pathol."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299923001231?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299923001231?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T23:13:47Z","timestamp":1757978027000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299923001231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":57,"alternative-id":["S0014299923001231"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2023.175612","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2023.175612","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"175612"}}