{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T22:50:14Z","timestamp":1787698214876,"version":"build-2784847793"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T00:00:00Z","timestamp":1721865600000},"content-version":"vor","delay-in-days":328,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100023563","name":"INCT-INPD CNPq","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023563","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88881.516313\/2020-01"],"award-info":[{"award-number":["88881.516313\/2020-01"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["311709\/2018-4"],"award-info":[{"award-number":["311709\/2018-4"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["313114\/2021-8"],"award-info":[{"award-number":["313114\/2021-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["429035\/2018-7"],"award-info":[{"award-number":["429035\/2018-7"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["429121\/2018-0"],"award-info":[{"award-number":["429121\/2018-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004901","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","doi-asserted-by":"publisher","award":["03346-18"],"award-info":[{"award-number":["03346-18"]}],"id":[{"id":"10.13039\/501100004901","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.ejphar.2023.175926","type":"journal-article","created":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T01:51:52Z","timestamp":1689817912000},"page":"175926","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Psychoactive substances 25H-NBOMe and 25H-NBOH induce antidepressant-like behavior in male rats"],"prefix":"10.1016","volume":"955","author":[{"given":"Barbara G.","family":"Ferri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cintia O.","family":"de Novais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel S.","family":"Bonani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wellington A.","family":"de Barros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c2ngelo","family":"de F\u00e1tima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana C.","family":"Vilela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5059-9988","authenticated-orcid":false,"given":"Alexandre","family":"Giusti-Paiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1601","key":"10.1016\/j.ejphar.2023.175926_bib1","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.1098\/rstb.2011.0376","article-title":"Transcriptional regulation of the 5-HT1A receptor: implications for mental illness","volume":"367","author":"Albert","year":"2012","journal-title":"Phil. Trans. Roy. Soc. Lond. B Biol. Sci."},{"issue":"2","key":"10.1016\/j.ejphar.2023.175926_bib2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/acps.13249","article-title":"Therapeutic effects of classic serotonergic psychedelics: a systematic review of modern-era clinical studies","volume":"143","author":"Andersen","year":"2021","journal-title":"Acta Psychiatr. Scand."},{"issue":"1","key":"10.1016\/j.ejphar.2023.175926_bib3","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1124\/pr.118.015552","article-title":"International union of basic and clinical pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function","volume":"73","author":"Barnes","year":"2021","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ejphar.2023.175926_bib4","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.crtox.2021.11.002","article-title":"The new psychoactive substances 25H-NBOMe and 25H-NBOH induce abnormal development in the zebrafish embryo and interact in the DNA major groove","volume":"2","author":"Barros","year":"2021","journal-title":"Current Research in Toxicology"},{"key":"10.1016\/j.ejphar.2023.175926_bib5","article-title":"Synthesis of 25X-BOMes and 25X-NBOHs (X = H, I, Br) for pharmacological studies and as reference standards for forensic purposes","volume":"66","author":"Barros","year":"2021","journal-title":"Tetrahedron Lett."},{"issue":"6","key":"10.1016\/j.ejphar.2023.175926_bib6","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1124\/mol.106.028720","article-title":"Molecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists","volume":"70","author":"Braden","year":"2006","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ejphar.2023.175926_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2022.109352","article-title":"Considerations in assessing the abuse potential of psychedelics during drug development","volume":"224","author":"Calderon","year":"2023","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.ejphar.2023.175926_bib8","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00213-010-1784-0","article-title":"The serotonin 2C receptor potently modulates the head-twitch response in mice induced by a phenethylamine hallucinogen","volume":"209","author":"Canal","year":"2010","journal-title":"Psychopharmacology"},{"issue":"9","key":"10.1016\/j.ejphar.2023.175926_bib9","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1177\/0269881117725915","article-title":"Serotonin and brain function: a tale of two receptors","volume":"31","author":"Carhart-Harris","year":"2017","journal-title":"J. Psychopharmacol."},{"issue":"4","key":"10.1016\/j.ejphar.2023.175926_bib10","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s00221-013-3579-0","article-title":"Effects of psilocybin on hippocampal neurogenesis and extinction of trace fear conditioning","volume":"228","author":"Catlow","year":"2013","journal-title":"Exp. Brain Res."},{"issue":"4","key":"10.1016\/j.ejphar.2023.175926_bib11","first-page":"252","article-title":"The therapeutic role of 5-HT1A and 5-HT2A receptors in depression","volume":"29","author":"Celada","year":"2004","journal-title":"J. Psychiatry Neurosci.: J. Psychiatr. Neurosci."},{"issue":"10128","key":"10.1016\/j.ejphar.2023.175926_bib12","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/S0140-6736(17)32802-7","article-title":"Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis","volume":"391","author":"Cipriani","year":"2018","journal-title":"Lancet (London, England)"},{"issue":"5","key":"10.1016\/j.ejphar.2023.175926_bib13","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1007\/s11011-020-00547-w","article-title":"Toxicity of ayahuasca after 28 days daily exposure and effects on monoamines and brain-derived neurotrophic factor (BDNF) in brain of Wistar rats","volume":"35","author":"Cola\u00e7o","year":"2020","journal-title":"Metab. Brain Dis."},{"issue":"5","key":"10.1016\/j.ejphar.2023.175926_bib14","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1021\/acschemneuro.7b00042","article-title":"The rodent forced swim test measures stress-coping strategy, not depression-like behavior","volume":"8","author":"Commons","year":"2017","journal-title":"ACS Chem. Neurosci."},{"issue":"4\u20135","key":"10.1016\/j.ejphar.2023.175926_bib15","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.neubiorev.2005.03.008","article-title":"Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test","volume":"29","author":"Cryan","year":"2005","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.ejphar.2023.175926_bib16","doi-asserted-by":"crossref","DOI":"10.1111\/adb.12850","article-title":"25B-NBOMe, a novel N-2-methoxybenzyl-phenethylamine (NBOMe) derivative, may induce rewarding and reinforcing effects via a dopaminergic mechanism: evidence of abuse potential","volume":"25","author":"Custodio","year":"2020","journal-title":"Addiction Biol."},{"key":"10.1016\/j.ejphar.2023.175926_bib17","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.neuropharm.2018.02.033","article-title":"Comparative neuropharmacology of N-(2-methoxybenzyl)-2,5-dimethoxyphenethylamine (NBOMe) hallucinogens and their 2C counterparts in male rats","volume":"142","author":"Elmore","year":"2018","journal-title":"Neuropharmacology"},{"issue":"6","key":"10.1016\/j.ejphar.2023.175926_bib18","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s00213-014-3739-3","article-title":"Hallucinogen-like effects of 2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol (25CN-NBOH), a novel N-benzylphenethylamine with 100-fold selectivity for 5-HT\u2082A receptors, in mice","volume":"232","author":"Fantegrossi","year":"2015","journal-title":"Psychopharmacology"},{"issue":"4","key":"10.1016\/j.ejphar.2023.175926_bib19","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1080\/09540261.2018.1481827","article-title":"Psychedelics as anti-inflammatory agents","volume":"30","author":"Flanagan","year":"2018","journal-title":"Int. Rev. Psychiatr."},{"issue":"3","key":"10.1016\/j.ejphar.2023.175926_bib20","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.neuron.2007.01.008","article-title":"Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior","volume":"53","author":"Gonz\u00e1lez-Maeso","year":"2007","journal-title":"Neuron"},{"issue":"11","key":"10.1016\/j.ejphar.2023.175926_bib21","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/s41583-019-0221-6","article-title":"The future of rodent models in depression research","volume":"20","author":"Gururajan","year":"2019","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ejphar.2023.175926_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2019.107933","article-title":"Correlation between the potency of hallucinogens in the mouse head-twitch response assay and their behavioral and subjective effects in other species","volume":"167","author":"Halberstadt","year":"2020","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ejphar.2023.175926_bib23","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/7854_2016_466","article-title":"Effect of hallucinogens on unconditioned behavior","volume":"36","author":"Halberstadt","year":"2018","journal-title":"Current Topics in Behavioral Neurosciences"},{"issue":"8","key":"10.1016\/j.ejphar.2023.175926_bib24","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1007\/s00213-021-05860-5","article-title":"Tolerance to neurochemical and behavioral effects of the hallucinogen 25I-NBOMe","volume":"238","author":"Herian","year":"2021","journal-title":"Psychopharmacology"},{"issue":"1","key":"10.1016\/j.ejphar.2023.175926_bib25","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3109\/08923979409029898","article-title":"Immunological consequences of in vitro exposure to lysergic acid diethylamide (LSD)","volume":"16","author":"House","year":"1994","journal-title":"Immunopharmacol. Immunotoxicol."},{"key":"10.1016\/j.ejphar.2023.175926_bib26","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2022.1076459","article-title":"Serotonergic psychedelics for depression: what do we know about neurobiological mechanisms of action?","volume":"13","author":"Husain","year":"2023","journal-title":"Front. Psychiatr."},{"key":"10.1016\/j.ejphar.2023.175926_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2023.109422","article-title":"Ketamine and serotonergic psychedelics: an update on the mechanisms and biosignatures underlying rapid-acting antidepressant treatment","volume":"226","author":"Johnston","year":"2023","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ejphar.2023.175926_bib28","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.jad.2022.09.168","article-title":"Psychedelic therapy for depressive symptoms: a systematic review and meta-analysis","volume":"322","author":"Ko","year":"2023","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.ejphar.2023.175926_bib29","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/978-1-4939-8994-2_5","article-title":"The forced swim test for depression-like behavior in rodents","volume":"1916","author":"Kraeuter","year":"2019","journal-title":"Methods Mol. Biol."},{"issue":"3","key":"10.1016\/j.ejphar.2023.175926_bib30","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s00213-006-0566-1","article-title":"The roles of 5-HT1A and 5-HT2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats","volume":"189","author":"Krebs-Thomson","year":"2006","journal-title":"Psychopharmacology"},{"issue":"17","key":"10.1016\/j.ejphar.2023.175926_bib31","first-page":"3270","article-title":"NBOMe: new potent hallucinogens--pharmacology, analytical methods, toxicities, fatalities: a review","volume":"19","author":"Kyriakou","year":"2015","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.ejphar.2023.175926_bib32","doi-asserted-by":"crossref","first-page":"312","DOI":"10.3389\/fnmol.2018.00312","article-title":"A single dose of 5-MeO-DMT stimulates cell proliferation, neuronal survivability, morphological and functional changes in adult mice ventral dentate gyrus","volume":"11","author":"Lima da Cruz","year":"2018","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.ejphar.2023.175926_bib33","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/7854_2017_478","article-title":"Hallucinogens and serotonin 5-ht2a receptor-mediated signaling pathways","volume":"36","author":"L\u00f3pez-Gim\u00e9nez","year":"2018","journal-title":"Current Topics in Behavioral Neurosciences"},{"issue":"1","key":"10.1016\/j.ejphar.2023.175926_bib34","article-title":"Is psilocybin an effective antidepressant and what is its Mechanism of action?. Cell Reports","volume":"4","author":"Mann","year":"2023","journal-title":"Medicine"},{"key":"10.1016\/j.ejphar.2023.175926_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.788155","article-title":"Therapeutic alliance and rapport modulate responses to psilocybin assisted therapy for depression","volume":"12","author":"Murphy","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"2","key":"10.1016\/j.ejphar.2023.175926_bib36","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1124\/pr.115.011478","volume":"68","author":"Nichols","year":"2016","journal-title":"Psychedelics. Pharmacological Reviews"},{"key":"10.1016\/j.ejphar.2023.175926_bib37","doi-asserted-by":"crossref","first-page":"3729","DOI":"10.2147\/JIR.S317182","article-title":"Anti-inflammatory effects of four psilocybin-containing magic mushroom water extracts in vitro on 15-lipoxygenase activity and on lipopolysaccharide-induced cyclooxygenase-2 and inflammatory cytokines in human U937 macrophage cells","volume":"14","author":"Nkadimeng","year":"2021","journal-title":"J. Inflamm. Res."},{"issue":"3","key":"10.1016\/j.ejphar.2023.175926_bib38","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1021\/acs.biochem.1c00812","article-title":"Biochemical mechanisms underlying psychedelic-induced neuroplasticity","volume":"61","author":"Olson","year":"2022","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.ejphar.2023.175926_bib39","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1590\/1516-4446-2014-1496","article-title":"Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report","volume":"37","author":"Os\u00f3rio","year":"2015","journal-title":"Rev. Bras. Psiquiatr."},{"issue":"6","key":"10.1016\/j.ejphar.2023.175926_bib40","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1007\/s00213-022-06098-5","article-title":"The role of serotonin neurotransmission in rapid antidepressant actions","volume":"239","author":"Pehrson","year":"2022","journal-title":"Psychopharmacology"},{"issue":"2\u20133","key":"10.1016\/j.ejphar.2023.175926_bib41","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0014-2999(79)90366-2","article-title":"Immobility induced by forced swimming in rats: effects of agents which modify central catecholamine and serotonin activity","volume":"57","author":"Porsolt","year":"1979","journal-title":"Eur. J. Pharmacol."},{"issue":"11","key":"10.1016\/j.ejphar.2023.175926_bib42","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1517\/13543784.2012.719872","article-title":"5-HT2 ligands in the treatment of anxiety and depression","volume":"21","author":"Quesseveur","year":"2012","journal-title":"Expet Opin. Invest. Drugs"},{"key":"10.1016\/j.ejphar.2023.175926_bib43","article-title":"Rapid antidepressant-like effect of non-hallucinogenic psychedelic analog lisuride, but not hallucinogenic psychedelic","volume":"222","author":"Qu","year":"2023","journal-title":"lipopolysaccharide-treated mice. Pharmacology, Biochemistry, and Behavior"},{"issue":"1","key":"10.1016\/j.ejphar.2023.175926_bib44","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1177\/07067437221111371","article-title":"The Canadian network for mood and anxiety treatments (CANMAT) task force report: serotonergic psychedelic treatments for major depressive disorder","volume":"68","author":"Rosenblat","year":"2023","journal-title":"Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie"},{"key":"10.1016\/j.ejphar.2023.175926_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2021.108679","article-title":"Co-administration of cannabidiol and ketamine induces antidepressant-like effects devoid of hyperlocomotor side-effects","volume":"195","author":"Sartim","year":"2021","journal-title":"Neuropharmacology"},{"issue":"2","key":"10.1016\/j.ejphar.2023.175926_bib46","doi-asserted-by":"crossref","first-page":"131","DOI":"10.2165\/11530280-000000000-00000","article-title":"Therapeutic options for treatment-resistant depression","volume":"24","author":"Shelton","year":"2010","journal-title":"CNS Drugs"},{"issue":"8","key":"10.1016\/j.ejphar.2023.175926_bib47","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106533","article-title":"Psychedelic N,N-dimethyltryptamine and 5-methoxy-N,N-dimethyltryptamine modulate innate and adaptive inflammatory responses through the sigma-1 receptor of human monocyte-derived dendritic cells","volume":"9","author":"Szabo","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ejphar.2023.175926_bib48","doi-asserted-by":"crossref","first-page":"450","DOI":"10.3389\/fpsyt.2018.00450","article-title":"DSM-5 criteria and depression severity: implications for clinical practice","volume":"9","author":"Tolentino","year":"2018","journal-title":"Front. Psychiatr."},{"key":"10.1016\/j.ejphar.2023.175926_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.802581","article-title":"Rewiring of the serotonin system in major depression","volume":"12","author":"Vahid-Ansari","year":"2021","journal-title":"Front. Psychiatr."},{"key":"10.1016\/j.ejphar.2023.175926_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2022.109294","article-title":"Mescaline: the forgotten psychedelic","volume":"222","author":"Vamvakopoulou","year":"2023","journal-title":"Neuropharmacology"},{"issue":"6633","key":"10.1016\/j.ejphar.2023.175926_bib51","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1126\/science.adf0435","article-title":"Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors","volume":"379","author":"Vargas","year":"2023","journal-title":"Science (New York, N.Y.)"},{"issue":"17","key":"10.1016\/j.ejphar.2023.175926_bib52","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1097\/00001756-199812010-00024","article-title":"Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action","volume":"9","author":"Vollenweider","year":"1998","journal-title":"Neuroreport"},{"issue":"2","key":"10.1016\/j.ejphar.2023.175926_bib53","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s12640-020-00297-8","article-title":"Neurochemical and behavioral effects of a new hallucinogenic compound 25B-NBOMe in rats","volume":"39","author":"Wojtas","year":"2021","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.ejphar.2023.175926_bib54","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3389\/fnins.2020.00078","article-title":"NBOMes-highly potent and toxic alternatives of LSD","volume":"14","author":"Zawilska","year":"2020","journal-title":"Front. Neurosci."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299923004387?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299923004387?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T14:20:31Z","timestamp":1736346031000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299923004387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":54,"alternative-id":["S0014299923004387"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2023.175926","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Psychoactive substances 25H-NBOMe and 25H-NBOH induce antidepressant-like behavior in male rats","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2023.175926","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"175926"}}