{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:22:52Z","timestamp":1787498572412,"version":"build-2736575974"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81800051"],"award-info":[{"award-number":["81800051"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81960015"],"award-info":[{"award-number":["81960015"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82000062"],"award-info":[{"award-number":["82000062"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010857","name":"Jiangxi Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["20204BCJ23020"],"award-info":[{"award-number":["20204BCJ23020"]}],"id":[{"id":"10.13039\/501100010857","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011841","name":"Xinxiang Medical University","doi-asserted-by":"publisher","award":["202210472019"],"award-info":[{"award-number":["202210472019"]}],"id":[{"id":"10.13039\/501100011841","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011841","name":"Xinxiang Medical University","doi-asserted-by":"publisher","award":["XYBSKYZZ201812"],"award-info":[{"award-number":["XYBSKYZZ201812"]}],"id":[{"id":"10.13039\/501100011841","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011841","name":"Xinxiang Medical University","doi-asserted-by":"publisher","award":["XYBSKYZZ202108"],"award-info":[{"award-number":["XYBSKYZZ202108"]}],"id":[{"id":"10.13039\/501100011841","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017700","name":"Henan Provincial Science and Technology Research Project","doi-asserted-by":"publisher","award":["212102310319"],"award-info":[{"award-number":["212102310319"]}],"id":[{"id":"10.13039\/501100017700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021183","name":"Science Fund for Distinguished Young Scholars of Jiangxi Province","doi-asserted-by":"publisher","award":["20212ACB216008"],"award-info":[{"award-number":["20212ACB216008"]}],"id":[{"id":"10.13039\/501100021183","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.ejphar.2024.176315","type":"journal-article","created":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T10:19:15Z","timestamp":1704277155000},"page":"176315","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Sodium butyrate alleviates right ventricular hypertrophy in pulmonary arterial hypertension by inhibiting H19 and affecting the activation of let-7g-5p\/IGF1 receptor\/ERK"],"prefix":"10.1016","volume":"965","author":[{"given":"Ming-hui","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-liang","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-guang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liao-fan","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan-rong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-jing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-fang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9017-6680","authenticated-orcid":false,"given":"Tian-tian","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2024.176315_bib1","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1164\/rccm.202110-2274OC","article-title":"Macrophage-NLRP3 activation promotes right ventricle failure in pulmonary arterial hypertension","volume":"206","author":"Al-Qazazi","year":"2022","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.ejphar.2024.176315_bib2","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1001\/jamacardio.2016.3591","article-title":"Trends and outcomes of pulmonary arterial hypertension-related hospitalizations in the United States: analysis of the nationwide inpatient sample database from 2001 through 2012","volume":"1","author":"Anand","year":"2016","journal-title":"JAMA cardiology"},{"key":"10.1016\/j.ejphar.2024.176315_bib3","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.intimp.2019.04.042","article-title":"LncRNA H19\/miR-let-7 axis participates in the regulation of ox-LDL-induced endothelial cell injury via targeting periostin","volume":"72","author":"Cao","year":"2019","journal-title":"Int. Immunopharm."},{"key":"10.1016\/j.ejphar.2024.176315_bib4","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.ebiom.2019.08.001","article-title":"MicroRNA let-7-TGFBR3 signalling regulates cardiomyocyte apoptosis after infarction","volume":"46","author":"Chen","year":"2019","journal-title":"EBioMedicine"},{"key":"10.1016\/j.ejphar.2024.176315_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.175262","article-title":"Melatonin activates the Mst1-Nrf2 signaling to alleviate cardiac hypertrophy in pulmonary arterial hypertension","volume":"933","author":"Chen","year":"2022","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ejphar.2024.176315_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.117848","article-title":"Contribution of reactive oxygen species via the OXR1 signaling pathway in the pathogenesis of monocrotaline-induced pulmonary arterial hypertension: the protective role of Crocin","volume":"256","author":"Dianat","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.ejphar.2024.176315_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0204254","article-title":"Oxygen therapy may worsen the survival rate in rats with monocrotaline-induced pulmonary arterial hypertension","volume":"13","author":"Fujita","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.ejphar.2024.176315_bib8","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.bcp.2014.07.011","article-title":"Dissecting histone deacetylase role in pulmonary arterial smooth muscle cell proliferation and migration","volume":"91","author":"Galletti","year":"2014","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ejphar.2024.176315_bib9","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.658354","article-title":"Impact of bacterial metabolites on gut barrier function and host immunity: a focus on bacterial metabolism and its relevance for intestinal inflammation","volume":"12","author":"Gasaly","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ejphar.2024.176315_bib10","doi-asserted-by":"crossref","first-page":"3735","DOI":"10.1111\/jcmm.16164","article-title":"Up-regulation of circRNA_0068481 promotes right ventricular hypertrophy in PAH patients via regulating miR-646\/miR-570\/miR-885","volume":"25","author":"Guo","year":"2021","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.ejphar.2024.176315_bib11","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1161\/CIRCHEARTFAILURE.110.949933","article-title":"Characteristics and outcome after hospitalization for acute right heart failure in patients with pulmonary arterial hypertension","volume":"4","author":"Haddad","year":"2011","journal-title":"Circulation. Heart failure."},{"key":"10.1016\/j.ejphar.2024.176315_bib12","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12856","article-title":"The lncRNA H19 binding to let-7b promotes hippocampal glial cell activation and epileptic seizures by targeting Stat3 in a rat model of temporal lobe epilepsy","volume":"53","author":"Han","year":"2020","journal-title":"Cell Prolif."},{"key":"10.1016\/j.ejphar.2024.176315_bib13","doi-asserted-by":"crossref","DOI":"10.3390\/cells10081892","article-title":"Role of long non-coding RNAs in pulmonary arterial hypertension","volume":"10","author":"Han","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.ejphar.2024.176315_bib14","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1080\/14737159.2021.1944808","article-title":"Dysregulation of lncRNA-H19 in cardiometabolic diseases and the molecular mechanism involved : a systematic review","volume":"21","author":"Hern\u00e1ndez-Aguilar","year":"2021","journal-title":"Expert Rev. Mol. Diagn."},{"key":"10.1016\/j.ejphar.2024.176315_bib15","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/S2213-2600(15)00543-3","article-title":"A global view of pulmonary hypertension","volume":"4","author":"Hoeper","year":"2016","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.ejphar.2024.176315_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2022.101706","article-title":"Short-chain fatty acid metabolism and multiple effects on cardiovascular diseases","volume":"81","author":"Hu","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.ejphar.2024.176315_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22189916","article-title":"The short-chain fatty acid butyrate attenuates pulmonary vascular remodeling and inflammation in hypoxia-induced pulmonary hypertension","volume":"22","author":"Karoor","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ejphar.2024.176315_bib18","doi-asserted-by":"crossref","first-page":"277","DOI":"10.4110\/in.2014.14.6.277","article-title":"Gut microbiota-derived short-chain Fatty acids, T cells, and inflammation","volume":"14","author":"Kim","year":"2014","journal-title":"Immune network"},{"key":"10.1016\/j.ejphar.2024.176315_bib19","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21238901","article-title":"Epigenetic regulation of pulmonary arterial hypertension-induced vascular and right ventricular remodeling: new opportunities?","volume":"21","author":"Kocken","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ejphar.2024.176315_bib20","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.yjmcc.2020.08.013","article-title":"Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn","volume":"148","author":"Kurahara","year":"2020","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.ejphar.2024.176315_bib21","doi-asserted-by":"crossref","first-page":"H702","DOI":"10.1152\/ajpheart.00046.2021","article-title":"Distinct time courses and mechanics of right ventricular hypertrophy and diastolic stiffening in a male rat model of pulmonary arterial hypertension","volume":"321","author":"Kwan","year":"2021","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.ejphar.2024.176315_bib22","doi-asserted-by":"crossref","first-page":"663","DOI":"10.2174\/138161207780249146","article-title":"The IGF-I signaling pathway","volume":"13","author":"Laviola","year":"2007","journal-title":"Curr. Pharmaceut. Des."},{"key":"10.1016\/j.ejphar.2024.176315_bib23","doi-asserted-by":"crossref","first-page":"D189","DOI":"10.1093\/nar\/gkz804","article-title":"RNAInter in 2020: RNA interactome repository with increased coverage and annotation","volume":"48","author":"Lin","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ejphar.2024.176315_bib24","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/cvr\/cvw078","article-title":"The H19 long noncoding RNA is a novel negative regulator of cardiomyocyte hypertrophy","volume":"111","author":"Liu","year":"2016","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.ejphar.2024.176315_bib25","doi-asserted-by":"crossref","first-page":"21191","DOI":"10.18632\/aging.203403","article-title":"LncRNA PITPNA-AS1 promotes gastric cancer by increasing SOX4 expression via inhibition of miR-92a-3p","volume":"13","author":"Liu","year":"2021","journal-title":"Aging"},{"key":"10.1016\/j.ejphar.2024.176315_bib26","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1093\/emph\/eoy008","article-title":"Lost in translation: the 3'-UTR of IGF1R as an ancient long noncoding RNA","author":"Mainieri","year":"2018","journal-title":"Evolution, medicine, and public health"},{"key":"10.1016\/j.ejphar.2024.176315_bib27","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2021.12275","article-title":"Interactions between the ERK1\/2 signaling pathway and PCAF play a key role in PE-induced cardiomyocyte hypertrophy","volume":"24","author":"Mao","year":"2021","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.ejphar.2024.176315_bib28","doi-asserted-by":"crossref","first-page":"6","DOI":"10.5334\/gh.384","article-title":"Long-term outcomes and factors associated with mortality in patients with moderate to severe pulmonary hypertension in Kenya","volume":"15","author":"Ngunga","year":"2020","journal-title":"Global heart"},{"key":"10.1016\/j.ejphar.2024.176315_bib29","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1161\/CIRCULATIONAHA.120.047626","article-title":"Identification of long noncoding RNA H19 as a new biomarker and therapeutic target in right ventricular failure in pulmonary arterial hypertension","volume":"142","author":"Omura","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.ejphar.2024.176315_bib30","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1080\/01913120701719189","article-title":"Common tasks in microscopic and ultrastructural image analysis using ImageJ","volume":"31","author":"Papadopulos","year":"2007","journal-title":"Ultrastruct. Pathol."},{"key":"10.1016\/j.ejphar.2024.176315_bib31","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1186\/s12974-016-0765-6","article-title":"The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats","volume":"13","author":"Park","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.ejphar.2024.176315_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12012-017-9406-2","article-title":"Sodium butyrate controls cardiac hypertrophy in experimental models of rats","volume":"18","author":"Patel","year":"2018","journal-title":"Cardiovasc. Toxicol."},{"key":"10.1016\/j.ejphar.2024.176315_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2022.115245","article-title":"Integrating epigenetics and metabolomics to advance treatments for pulmonary arterial hypertension","volume":"204","author":"Ranasinghe","year":"2022","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ejphar.2024.176315_bib34","doi-asserted-by":"crossref","DOI":"10.4414\/smw.2012.13596","article-title":"Butyric acid: what is the future for this old substance?","volume":"142","author":"Sossai","year":"2012","journal-title":"Swiss Med. Wkly."},{"key":"10.1016\/j.ejphar.2024.176315_bib35","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1097\/FJC.0000000000000862","article-title":"Dihydroartemisinin attenuates pulmonary hypertension through inhibition of pulmonary vascular remodeling in rats","volume":"76","author":"Tang","year":"2020","journal-title":"J. Cardiovasc. Pharmacol."},{"key":"10.1016\/j.ejphar.2024.176315_bib36","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/s12890-022-01939-7","article-title":"Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension","volume":"22","author":"Tang","year":"2022","journal-title":"BMC Pulm. Med."},{"key":"10.1016\/j.ejphar.2024.176315_bib37","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.ijcard.2018.01.053","article-title":"Relevance of the TAPSE\/PASP ratio in pulmonary arterial hypertension","volume":"266","author":"Tello","year":"2018","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.ejphar.2024.176315_bib38","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1253\/jcj.57.1120","article-title":"Insulin-like growth factor I receptors in human cardiac myocytes and their relation to myocardial hypertrophy","volume":"57","author":"Toyozaki","year":"1993","journal-title":"Jpn. Circ. J."},{"key":"10.1016\/j.ejphar.2024.176315_bib39","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/s41390-021-01840-9","article-title":"PATET ratio by Doppler echocardiography: noninvasive detection of pediatric pulmonary arterial hypertension","volume":"92","author":"Trittmann","year":"2022","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.ejphar.2024.176315_bib40","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.freeradbiomed.2022.02.027","article-title":"Silica nanoparticles induce pyroptosis and cardiac hypertrophy via ROS\/NLRP3\/Caspase-1 pathway","volume":"182","author":"Wang","year":"2022","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.ejphar.2024.176315_bib41","doi-asserted-by":"crossref","DOI":"10.3390\/biom12040496","article-title":"MicroRNAs in pulmonary hypertension, from pathogenesis to diagnosis and treatment","volume":"12","author":"Xu","year":"2022","journal-title":"Biomolecules"},{"key":"10.1016\/j.ejphar.2024.176315_bib42","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20130107","article-title":"Cardiac-targeting magnetic lipoplex delivery of SH-IGF1R plasmid attenuate norepinephrine-induced cardiac hypertrophy in murine heart","volume":"34","author":"Xu","year":"2014","journal-title":"Biosci. Rep."},{"key":"10.1016\/j.ejphar.2024.176315_bib43","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1161\/CIRCRESAHA.110.228437","article-title":"Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98\/let-7","volume":"108","author":"Yang","year":"2011","journal-title":"Circ. Res."},{"key":"10.1016\/j.ejphar.2024.176315_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.694702","article-title":"Molecular characterization and elucidation of pathways to identify novel therapeutic targets in pulmonary arterial hypertension","volume":"12","author":"Yao","year":"2021","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ejphar.2024.176315_bib45","doi-asserted-by":"crossref","first-page":"8139","DOI":"10.1111\/jcmm.14684","article-title":"Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2\/PGE2 pathway via a HDAC5\/HDAC6-dependent mechanism","volume":"23","author":"Zhang","year":"2019","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.ejphar.2024.176315_bib46","doi-asserted-by":"crossref","first-page":"F517","DOI":"10.1152\/ajprenal.00085.2021","article-title":"LncRNA GAS5 protects against TGF-\u03b2-induced renal fibrosis via the Smad3\/miRNA-142-5p axis","volume":"321","author":"Zhang","year":"2021","journal-title":"Am. J. Physiol. Ren. Physiol."},{"key":"10.1016\/j.ejphar.2024.176315_bib47","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/s13578-020-00435-x","article-title":"The functions of long non-coding RNAs in neural stem cell proliferation and differentiation","volume":"10","author":"Zhao","year":"2020","journal-title":"Cell Biosci."},{"key":"10.1016\/j.ejphar.2024.176315_bib48","first-page":"5747","article-title":"Upregulation of insulin-like growth factor-1 receptor (IGF-1R) reverses the inhibitory effect of let-7g-5p on migration and invasion of nasopharyngeal carcinoma","volume":"25","author":"Zhao","year":"2019","journal-title":"Med. Sci. Mon. Int. Med. J. Exp. Clin. Res. : international medical journal of experimental and clinical research"},{"key":"10.1016\/j.ejphar.2024.176315_bib49","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.biocel.2016.07.008","article-title":"MicroRNA let-7g regulates mouse granulosa cell autophagy by targeting insulin-like growth factor 1 receptor","volume":"78","author":"Zhou","year":"2016","journal-title":"Int. J. Biochem. Cell Biol."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299924000013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299924000013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T04:27:19Z","timestamp":1762144039000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299924000013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":49,"alternative-id":["S0014299924000013"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2024.176315","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sodium butyrate alleviates right ventricular hypertrophy in pulmonary arterial hypertension by inhibiting H19 and affecting the activation of let-7g-5p\/IGF1 receptor\/ERK","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2024.176315","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"176315"}}