{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T04:54:47Z","timestamp":1791608087898,"version":"4.3.4"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.ejphar.2024.176405","type":"journal-article","created":{"date-parts":[[2024,2,8]],"date-time":"2024-02-08T12:19:35Z","timestamp":1707394775000},"page":"176405","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["5- methylcytidine effectively improves spermatogenesis recovery in busulfan-induced oligoasthenospermia mice"],"prefix":"10.1016","volume":"967","author":[{"given":"Chengniu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taowen","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3785-7994","authenticated-orcid":false,"given":"Junze","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenran","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongping","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanqing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaorong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5429-9330","authenticated-orcid":false,"given":"Jianwu","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2024.176405_bib1","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.jconrel.2015.08.051","article-title":"N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice","volume":"217","author":"Andries","year":"2015","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.ejphar.2024.176405_bib2","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00018-019-03253-8","article-title":"Oxidative stress and male infertility: current knowledge of pathophysiology and role of antioxidant therapy in disease management","volume":"77","author":"Barati","year":"2020","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.ejphar.2024.176405_bib3","doi-asserted-by":"crossref","first-page":"D303","DOI":"10.1093\/nar\/gkx1030","article-title":"MODOMICS: a database of RNA modification pathways. 2017 update","volume":"46","author":"Boccaletto","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ejphar.2024.176405_bib4","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1038\/s41556-019-0361-y","article-title":"5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs","volume":"21","author":"Chen","year":"2019","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ejphar.2024.176405_bib5","article-title":"Dynamic transcriptomic m(5) C and its regulatory role in RNA processing. Wiley","volume":"12","author":"Chen","year":"2021","journal-title":"Interdiscip. Rev. RNA."},{"key":"10.1016\/j.ejphar.2024.176405_bib6","doi-asserted-by":"crossref","first-page":"1672","DOI":"10.1016\/j.neurobiolaging.2011.06.003","article-title":"Prevention of age-related changes in hippocampal levels of 5-methylcytidine by caloric restriction","volume":"33","author":"Chouliaras","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.ejphar.2024.176405_bib7","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0140-6736(96)08341-9","article-title":"Male infertility","volume":"349","author":"de Kretser","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.ejphar.2024.176405_bib8","doi-asserted-by":"crossref","first-page":"R53","DOI":"10.1530\/REP-18-0457","article-title":"The cytoskeleton in spermatogenesis","volume":"157","author":"Dunleavy","year":"2019","journal-title":"Reproduction"},{"key":"10.1016\/j.ejphar.2024.176405_bib9","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1080\/14737159.2019.1633917","article-title":"Contemporary genetics-based diagnostics of male infertility","volume":"19","author":"Ferlin","year":"2019","journal-title":"Expert Rev. Mol. Diagn"},{"key":"10.1016\/j.ejphar.2024.176405_bib10","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/cm.20539","article-title":"Loss of ASP but not ROPN1 reduces mammalian ciliary motility","volume":"69","author":"Fiedler","year":"2012","journal-title":"Cytoskeleton (Hoboken)"},{"key":"10.1016\/j.ejphar.2024.176405_bib11","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.bpobgyn.2017.05.002","article-title":"Genetic diagnostics of male infertility in clinical practice","volume":"44","author":"Flannigan","year":"2017","journal-title":"Best Pract. Res. Clin. Obstet. Gynaecol."},{"key":"10.1016\/j.ejphar.2024.176405_bib12","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.ygeno.2010.02.005","article-title":"TSEG-1, a novel member of histone H2A variants, participates in spermatogenesis via promoting apoptosis of spermatogenic cells","volume":"95","author":"Gu","year":"2010","journal-title":"Genomics"},{"key":"10.1016\/j.ejphar.2024.176405_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179697","article-title":"Inhibition of hepatitis B viral entry by nucleic acid polymers in HepaRG cells and primary human hepatocytes","volume":"12","author":"Guillot","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.ejphar.2024.176405_bib14","doi-asserted-by":"crossref","DOI":"10.1093\/molehr\/gaac031","article-title":"Alteration of RNA modification signature in human sperm correlates with sperm motility","volume":"28","author":"Guo","year":"2022","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.ejphar.2024.176405_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.gim.2023.100798","article-title":"Pathogenic variants in CLXN encoding the outer dynein arm docking-associated calcium-binding protein calaxin cause primary ciliary dyskinesia","volume":"25","author":"Hjeij","year":"2023","journal-title":"Genet. Med."},{"key":"10.1016\/j.ejphar.2024.176405_bib16","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.envint.2016.02.025","article-title":"Gene-gene and gene-environment interactions on risk of male infertility: focus on the metabolites","volume":"91","author":"Hu","year":"2016","journal-title":"Environ. Int."},{"key":"10.1016\/j.ejphar.2024.176405_bib17","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.fertnstert.2014.04.007","article-title":"Genetic variants in the RABL2A gene in fertile and oligoasthenospermic infertile men","volume":"102","author":"Jamsai","year":"2014","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.ejphar.2024.176405_bib18","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000502790","article-title":"Fine-needle aspiration cytology of the testes for the classification of azoospermia and its value in the assessment of male infertility","volume":"64","author":"Jashnani","year":"2020","journal-title":"Acta Cytol."},{"key":"10.1016\/j.ejphar.2024.176405_bib19","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.1242\/jcs.202721","article-title":"TSSK6 is required for gammaH2AX formation and the histone-to-protamine transition during spermiogenesis","volume":"130","author":"Jha","year":"2017","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.ejphar.2024.176405_bib20","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.ajhg.2018.07.005","article-title":"Bi-Allelic recessive loss-of-function variants in FANCM cause non-obstructive azoospermia","volume":"103","author":"Kasak","year":"2018","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ejphar.2024.176405_bib21","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1005821","article-title":"DNAH6 and its interactions with PCD genes in heterotaxy and primary ciliary dyskinesia","volume":"12","author":"Li","year":"2016","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ejphar.2024.176405_bib22","article-title":"MAEL gene contributes to bovine testicular development through the m5C-mediated splicing","volume":"26","author":"Liu","year":"2023","journal-title":"iScience"},{"key":"10.1016\/j.ejphar.2024.176405_bib23","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.omtn.2018.12.007","article-title":"Nucleotide modification alters MicroRNA-dependent silencing of MicroRNA switches","volume":"14","author":"Lockhart","year":"2019","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"10.1016\/j.ejphar.2024.176405_bib24","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ajhg.2008.10.001","article-title":"DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm","volume":"83","author":"Loges","year":"2008","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ejphar.2024.176405_bib25","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.mito.2015.07.007","article-title":"A genome-wide association study of mitochondrial DNA in Chinese men identifies two risk single nucleotide substitutions for idiopathic oligoasthenospermia","volume":"24","author":"Lu","year":"2015","journal-title":"Mitochondrion"},{"key":"10.1016\/j.ejphar.2024.176405_bib26","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1016\/S0022-5347(05)64355-8","article-title":"Understanding new genetics of male infertility","volume":"168","author":"Maduro","year":"2002","journal-title":"J. Urol."},{"key":"10.1016\/j.ejphar.2024.176405_bib27","first-page":"1","article-title":"Nuclear organization of the protamine locus","volume":"64","author":"Martins","year":"2007","journal-title":"Soc. Reprod. Fertil. Suppl."},{"key":"10.1016\/j.ejphar.2024.176405_bib28","doi-asserted-by":"crossref","first-page":"3046","DOI":"10.1128\/MCB.22.9.3046-3052.2002","article-title":"Asthenozoospermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) gene","volume":"22","author":"Nayernia","year":"2002","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.ejphar.2024.176405_bib29","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201846449","article-title":"The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban","volume":"20","author":"Niemeyer","year":"2019","journal-title":"EMBO Rep."},{"key":"10.1016\/j.ejphar.2024.176405_bib30","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1111\/andr.13314","article-title":"Testis-specific serine kinase 3 is required for sperm morphogenesis and male fertility","volume":"11","author":"Nozawa","year":"2023","journal-title":"Andrology"},{"key":"10.1016\/j.ejphar.2024.176405_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222312735","article-title":"The roles of luteinizing hormone, follicle-stimulating hormone and testosterone in spermatogenesis and folliculogenesis revisited","volume":"22","author":"Oduwole","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ejphar.2024.176405_bib32","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.fertnstert.2020.01.001","article-title":"Harnessing the full potential of reproductive genetics and epigenetics for male infertility in the era of \"big data\"","volume":"113","author":"Patel","year":"2020","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.ejphar.2024.176405_bib33","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1261\/rna.035808.112","article-title":"tRNAHis 5-methylcytidine levels increase in response to several growth arrest conditions in Saccharomyces cerevisiae","volume":"19","author":"Preston","year":"2013","journal-title":"RNA"},{"key":"10.1016\/j.ejphar.2024.176405_bib34","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/01480545.2016.1190739","article-title":"Toxicological assessment of Diplazium esculentum on the reproductive functions of male Swiss albino mouse","volume":"40","author":"Roy","year":"2017","journal-title":"Drug Chem. Toxicol."},{"key":"10.1016\/j.ejphar.2024.176405_bib35","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/nrd4278","article-title":"mRNA-based therapeutics--developing a new class of drugs","volume":"13","author":"Sahin","year":"2014","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ejphar.2024.176405_bib36","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ajhg.2019.11.013","article-title":"SYCP2 translocation-mediated dysregulation and frameshift variants cause human male infertility","volume":"106","author":"Schilit","year":"2020","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ejphar.2024.176405_bib37","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1093\/nar\/gkaa1193","article-title":"Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6","volume":"49","author":"Selmi","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ejphar.2024.176405_bib38","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s13072-020-00376-2","article-title":"Genome-wide occupancy reveals the localization of H1T2 (H1fnt) to repeat regions and a subset of transcriptionally active chromatin domains in rat spermatids","volume":"14","author":"Shalini","year":"2021","journal-title":"Epigenet. Chromatin"},{"key":"10.1016\/j.ejphar.2024.176405_bib39","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res."},{"key":"10.1016\/j.ejphar.2024.176405_bib40","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s40364-022-00362-8","article-title":"Biological roles of RNA m(5)C modification and its implications in Cancer immunotherapy","volume":"10","author":"Song","year":"2022","journal-title":"Biomark. Res."},{"key":"10.1016\/j.ejphar.2024.176405_bib41","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1073\/pnas.1310777111","article-title":"A heterozygous mutation of GALNTL5 affects male infertility with impairment of sperm motility","volume":"111","author":"Takasaki","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ejphar.2024.176405_bib42","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1016\/j.fertnstert.2012.11.037","article-title":"Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach","volume":"99","author":"Thoma","year":"2013","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.ejphar.2024.176405_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.104295","article-title":"Two resveratrol analogs, pinosylvin and 4,4'-dihydroxystilbene, improve oligoasthenospermia in a mouse model by attenuating oxidative stress via the Nrf2-ARE pathway","volume":"104","author":"Wang","year":"2020","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.ejphar.2024.176405_bib44","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1089\/ars.2012.4514","article-title":"Does prohibitin expression regulate sperm mitochondrial membrane potential, sperm motility, and male fertility?","volume":"17","author":"Wang","year":"2012","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.ejphar.2024.176405_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.biotechadv.2020.107534","article-title":"The challenge and prospect of mRNA therapeutics landscape","volume":"40","author":"Weng","year":"2020","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.ejphar.2024.176405_bib46","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.ajhg.2019.04.015","article-title":"Mutations in DNAH17, encoding a sperm-specific axonemal outer dynein arm heavy chain, cause isolated male infertility due to asthenozoospermia","volume":"105","author":"Whitfield","year":"2019","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ejphar.2024.176405_bib47","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/s41443-022-00531-1","article-title":"It puts the T's in fertility: testosterone and spermatogenesis","volume":"34","author":"Witherspoon","year":"2022","journal-title":"Int. J. Impot. Res."},{"key":"10.1016\/j.ejphar.2024.176405_bib48","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aal1910","article-title":"BMP8A sustains spermatogenesis by activating both SMAD1\/5\/8 and SMAD2\/3 in spermatogonia","volume":"10","author":"Wu","year":"2017","journal-title":"Sci. Signal."},{"key":"10.1016\/j.ejphar.2024.176405_bib49","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106585","article-title":"Effect of cyanotoxins on the hypothalamic-pituitary-gonadal axis in male adult mouse","volume":"9","author":"Xiong","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ejphar.2024.176405_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2020.144635","article-title":"The dynamics and regulation of microfilament during spermatogenesis","volume":"744","author":"Yang","year":"2020","journal-title":"Gene"},{"key":"10.1016\/j.ejphar.2024.176405_bib51","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/jcmm.13945","article-title":"Dynein axonemal intermediate chain 2 plays a role in gametogenesis by activation of Stat3","volume":"23","author":"Yang","year":"2019","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.ejphar.2024.176405_bib52","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/s41436-018-0015-7","article-title":"A homozygous FANCM frameshift pathogenic variant causes male infertility","volume":"21","author":"Yin","year":"2019","journal-title":"Genet. Med."},{"key":"10.1016\/j.ejphar.2024.176405_bib53","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1039\/C9CC00274J","article-title":"Bisulfite-free and base-resolution analysis of 5-methylcytidine and 5-hydroxymethylcytidine in RNA with peroxotungstate","volume":"55","author":"Yuan","year":"2019","journal-title":"Chem. Commun (Camb)."},{"key":"10.1016\/j.ejphar.2024.176405_bib54","article-title":"A diagnostic model to improve the predictability of natural pregnancy potential in patients with oligoasthenospermia","volume":"26","author":"Zhang","year":"2020","journal-title":"Med. Sci. Mon. Int. Med. J. Exp. Clin. Res."},{"key":"10.1016\/j.ejphar.2024.176405_bib55","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.ydbio.2012.04.026","article-title":"KLC3 is involved in sperm tail midpiece formation and sperm function","volume":"366","author":"Zhang","year":"2012","journal-title":"Dev. Biol."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299924000931?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299924000931?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T23:29:40Z","timestamp":1757978980000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299924000931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":55,"alternative-id":["S0014299924000931"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2024.176405","relation":{},"ISSN":["0014-2999"],"issn-type":[{"value":"0014-2999","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"5- methylcytidine effectively improves spermatogenesis recovery in busulfan-induced oligoasthenospermia mice","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2024.176405","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"176405"}}