{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T06:24:11Z","timestamp":1757312651912,"version":"3.37.3"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,1]],"date-time":"2024-11-01T00:00:00Z","timestamp":1730419200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004410","name":"T\u00dcB\u0130TAK","doi-asserted-by":"publisher","award":["222S711"],"award-info":[{"award-number":["222S711"]}],"id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031408","name":"Suleyman Demirel University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100031408","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004935","name":"S\u00fcleyman Demirel \u00dcniversitesi","doi-asserted-by":"publisher","award":["TYL-2019-7406"],"award-info":[{"award-number":["TYL-2019-7406"]}],"id":[{"id":"10.13039\/501100004935","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmacology"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1016\/j.ejphar.2024.176949","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T04:49:17Z","timestamp":1724734157000},"page":"176949","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["\u201cInvestigation of the potential cellular changes induced by magnesium sulfate and salubrinal in a lipopolysaccharide-induced chorioamnionitis model\u201d"],"prefix":"10.1016","volume":"982","author":[{"given":"Halil","family":"Asci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7933-0453","authenticated-orcid":false,"given":"Mehtap","family":"Savran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammet Y.","family":"Tepebasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3739-9580","authenticated-orcid":false,"given":"Ilter","family":"Ilhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasif F.","family":"Karakuyu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3850-0137","authenticated-orcid":false,"given":"Orhan B.","family":"Imeci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3875-9365","authenticated-orcid":false,"given":"Mehmet A.","family":"Sevuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mekin","family":"Sezik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1835-1082","authenticated-orcid":false,"given":"Ozlem","family":"Ozmen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejphar.2024.176949_bib1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.bcp.2018.02.029","article-title":"Salubrinal and robenacoxib treatment after global cerebral ischemia. Exploring the interactions between ER stress and inflammation","volume":"151","author":"Anuncibay-Soto","year":"2018","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ejphar.2024.176949_bib2","doi-asserted-by":"crossref","first-page":"382.e1","DOI":"10.1016\/j.ajog.2016.03.032","article-title":"Maternal magnesium sulfate fetal neuroprotective effects to the fetus: inhibition of neuronal nitric oxide synthase and nuclear factor kappa-light-chain-enhancer of activated B cells activation in a rodent model","volume":"215","author":"Beloosesky","year":"2016","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.ejphar.2024.176949_bib3","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/1742-2094-10-92","article-title":"Inhibition of astroglial NF-\u03baB enhances oligodendrogenesis following spinal cord injury","volume":"10","author":"Bracchi-Ricard","year":"2013","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.ejphar.2024.176949_bib4","doi-asserted-by":"crossref","first-page":"258","DOI":"10.3724\/SP.J.1263.2012.02292","article-title":"Salubrinal protects against tunicamycin and hypoxia induced cardiomyocyte apoptosis via the PERK-eIF2\u03b1 signaling pathwaySalubrinal protects against tunicamycin and hypoxia induced cardiomyocyte apoptosis via the PERK-eIF2\u03b1 signaling pathway","volume":"9","author":"Chun-Lei","year":"2012","journal-title":"J. Geriatric Cardiology"},{"key":"10.1016\/j.ejphar.2024.176949_bib5","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ejogrb.2015.02.034","article-title":"Term histologic chorioamnionitis: a heterogeneous condition","volume":"188","author":"Conti","year":"2015","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"key":"10.1016\/j.ejphar.2024.176949_bib6","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jneumeth.2016.02.002","article-title":"Novel pharmaceutical treatments for minimal traumatic brain injury and evaluation of animal models and methodologies supporting their development","volume":"272","author":"Deselms","year":"2016","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.ejphar.2024.176949_bib7","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1046\/j.0953-816x.2001.01474.x","article-title":"Bacterial endotoxin sensitizes the immature brain to hypoxic--ischaemic injury","volume":"13","author":"Eklind","year":"2001","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.ejphar.2024.176949_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.531543","article-title":"Maternal-fetal inflammation in the placenta and the developmental origins of health and disease","volume":"11","author":"Goldstein","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ejphar.2024.176949_bib9","doi-asserted-by":"crossref","first-page":"E95","DOI":"10.1097\/AOG.0000000000002236","article-title":"Committee opinion No. 712: intrapartum management of intraamniotic infection","volume":"130","author":"Heine","year":"2017","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ejphar.2024.176949_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.neurobiolaging.2011.10.007","article-title":"Salubrinal attenuates \u03b2-amyloid-induced neuronal death and microglial activation by inhibition of the NF-\u03baB pathway","volume":"33","author":"Huang","year":"2012","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.ejphar.2024.176949_bib11","doi-asserted-by":"crossref","first-page":"3732","DOI":"10.1080\/14767058.2019.1583735","article-title":"Fetal neuroprotective mechanism of maternal magnesium sulfate for late gestation inflammation: in a rodent model","volume":"33","author":"Khatib","year":"2020","journal-title":"J. Matern. Fetal Neonatal Med."},{"key":"10.1016\/j.ejphar.2024.176949_bib12","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/S0140-6736(08)60380-3","article-title":"Neurodevelopmental disabilities and special care of 5-year-old children born before 33 weeks of gestation (the EPIPAGE study): a longitudinal cohort study","volume":"371","author":"Larroque","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.ejphar.2024.176949_bib13","doi-asserted-by":"crossref","first-page":"7938","DOI":"10.1007\/s12035-016-0278-4","article-title":"Magnesium sulfate provides neuroprotection in eclampsia-like seizure model by ameliorating neuroinflammation and brain edema","volume":"54","author":"Li","year":"2017","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.ejphar.2024.176949_bib14","doi-asserted-by":"crossref","first-page":"16275","DOI":"10.3390\/ijms160716275","article-title":"Experimental evidence shows salubrinal, an eIF2\u03b1 dephosphorylation inhibitor, reduces xenotoxicant-induced cellular damage","volume":"16","author":"Matsuoka","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ejphar.2024.176949_bib15","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.clp.2018.01.015","article-title":"Perinatal brain injury: mechanisms, prevention, and outcomes","volume":"45","author":"Novak","year":"2018","journal-title":"Clin. Perinatol."},{"key":"10.1016\/j.ejphar.2024.176949_bib16","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1146\/annurev-pathol-012513-104649","article-title":"The role of endoplasmic reticulum stress in human pathology","volume":"10","author":"Oakes","year":"2015","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.ejphar.2024.176949_bib17","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1053\/hupa.2002.31291","article-title":"Re-evaluation of chorioamnionitis and funisitis with a special reference to subacute chorioamnionitis","volume":"33","author":"Ohyama","year":"2002","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.ejphar.2024.176949_bib18","doi-asserted-by":"crossref","first-page":"501","DOI":"10.4097\/kja.23207","article-title":"Dexpanthenol protects against lipopolysaccharide-induced acute kidney injury by restoring aquaporin-2 levels via regulation of the silent information regulator 1 signaling pathway","volume":"76","author":"\u00d6zden","year":"2023","journal-title":"Korean J Anesthesiol"},{"key":"10.1016\/j.ejphar.2024.176949_bib19","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1055\/s-2007-999710","article-title":"Histologic chorioamnionitis in pregnancies of various gestational ages. II: implications in preterm labor","volume":"5","author":"Perkins","year":"1988","journal-title":"Am. J. Perinatol."},{"key":"10.1016\/j.ejphar.2024.176949_bib20","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nrm2199","article-title":"Signal integration in the endoplasmic reticulum unfolded protein response","volume":"8","author":"Ron","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ejphar.2024.176949_bib21","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nature12808","article-title":"Transcranial amelioration of inflammation and cell death after brain injury","volume":"505","author":"Roth","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.ejphar.2024.176949_bib22","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s12017-015-8340-3","article-title":"The neuroprotective effect of salubrinal in a mouse model of traumatic brain injury","volume":"17","author":"Rubovitch","year":"2015","journal-title":"NeuroMolecular Med."},{"key":"10.1016\/j.ejphar.2024.176949_bib23","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/aji.12118","article-title":"Magnesium sulfate increases intracellular magnesium reducing inflammatory cytokine release in neonates","volume":"70","author":"Suzuki-Kakisaka","year":"2013","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.ejphar.2024.176949_bib24","doi-asserted-by":"crossref","first-page":"827","DOI":"10.4103\/1673-5374.232477","article-title":"Inhibition of endoplasmic reticulum stress alleviates secondary injury after traumatic brain injury","volume":"13","author":"Tan","year":"2018","journal-title":"Neural Regen Res"},{"key":"10.1016\/j.ejphar.2024.176949_bib25","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.nlm.2019.03.002","article-title":"Salubrinal offers neuroprotection through suppressing endoplasmic reticulum stress, autophagy and apoptosis in a mouse traumatic brain injury model","volume":"161","author":"Wang","year":"2019","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.ejphar.2024.176949_bib26","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1111\/jog.13444","article-title":"Fingolimod against endotoxin-induced fetal brain injury in a rat model","volume":"43","author":"Yavuz","year":"2017","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"10.1016\/j.ejphar.2024.176949_bib27","doi-asserted-by":"crossref","first-page":"25935","DOI":"10.1074\/jbc.R400008200","article-title":"Signaling the unfolded protein response from the endoplasmic reticulum","volume":"279","author":"Zhang","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ejphar.2024.176949_bib28","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s11064-022-03536-w","article-title":"Zinc accumulation aggravates cerebral ischemia\/reperfusion injury through inducing endoplasmic reticulum stress","volume":"47","author":"Zhao","year":"2022","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.ejphar.2024.176949_bib29","first-page":"1532","article-title":"Effects of magnesium sulfate on neuron apoptosis and expression of caspase-3, bax and bcl-2 after cerebral ischemia-reperfusion injury","volume":"116","author":"Zhou","year":"2003","journal-title":"Chin. Med. J."}],"container-title":["European Journal of Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299924006381?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014299924006381?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T19:06:28Z","timestamp":1726254388000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014299924006381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":29,"alternative-id":["S0014299924006381"],"URL":"https:\/\/doi.org\/10.1016\/j.ejphar.2024.176949","relation":{},"ISSN":["0014-2999"],"issn-type":[{"type":"print","value":"0014-2999"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"\u201cInvestigation of the potential cellular changes induced by magnesium sulfate and salubrinal in a lipopolysaccharide-induced chorioamnionitis model\u201d","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmacology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejphar.2024.176949","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"176949"}}