{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:06:57Z","timestamp":1790276817007,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Lea and Arvo Ylpp\u00f6 Foundation."},{"name":"Academy of Finland."},{"DOI":"10.13039\/501100004012","name":"Jane and Aatos Erkko Foundation.","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004012","id-type":"DOI","asserted-by":"crossref"}]},{"name":"M\u00e4rta Donner Foundation"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","ejpn-journal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Paediatric Neurology"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.ejpn.2015.10.009","type":"journal-article","created":{"date-parts":[[2015,11,14]],"date-time":"2015-11-14T15:30:08Z","timestamp":1447515008000},"page":"38-44","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Peripheral neuropathy in patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency \u2013 A follow-up EMG study of 12 patients"],"prefix":"10.1016","volume":"20","author":[{"given":"Immonen","family":"Tuuli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahola","family":"Emilia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toppila","family":"Jussi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lapatto","family":"Risto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyni","family":"Tiina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauronen","family":"Leena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejpn.2015.10.009_bib1","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1023\/A:1005504223140","article-title":"Disorders of mitochondrial fatty acyl-CoA \u03b2-oxidation","volume":"22","author":"Wanders","year":"1999","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.ejpn.2015.10.009_bib2","doi-asserted-by":"crossref","first-page":"2961","DOI":"10.1093\/hmg\/10.26.2961","article-title":"Dissecting a population genome for targeted screening of disease mutations","volume":"10","author":"Pastinen","year":"2001","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.ejpn.2015.10.009_bib3","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.ymgme.2005.02.002","article-title":"Neonatal screening for defects of the mitochondrial trifunctional protein","volume":"85","author":"Sanders","year":"2005","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.ejpn.2015.10.009_bib4","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/S0140-6736(89)90300-0","article-title":"Sudden infant death and long-chain 3-hydroxyacyl-CoA dehydrogenase","volume":"2","author":"Wanders","year":"1989","journal-title":"Lancet"},{"issue":"Suppl. 2","key":"10.1016\/j.ejpn.2015.10.009_bib5","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF01804230","article-title":"Familial hypoketotic hypoglycaemia associated with peripheral neuropathy, pigmentary retinopathy and C6\u2013C14 hydroxydicarboxylic aciduria. A new defect in fatty acid oxidation?","volume":"11","author":"Poll-The","year":"1988","journal-title":"J Inherit Metab Dis"},{"issue":"5","key":"10.1016\/j.ejpn.2015.10.009_bib6","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/S0022-3476(05)80039-3","article-title":"Progressive neuropathy and recurrent myoglobinuria in a child with long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency","volume":"118","author":"Dionici-Vici","year":"1991","journal-title":"J Pediatr"},{"key":"10.1016\/j.ejpn.2015.10.009_bib7","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/BF01958956","article-title":"Peripheral sensory-motor polyneuropathy, pigmentary retinopathy, and fatal cardiomyopathy in long-chain 3-hydroxy-acyl-CoA dehydrogenase deficiency","volume":"151","author":"Bertini","year":"1992","journal-title":"Eur J Pediatr"},{"issue":"1","key":"10.1016\/j.ejpn.2015.10.009_bib8","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/0887-8994(94)00109-F","article-title":"Clinical and neurophysiologic response of myopathy and neuropathy in long-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency to oral prednisone","volume":"12","author":"Tein","year":"1995","journal-title":"Pediatr Neurol"},{"issue":"3","key":"10.1016\/j.ejpn.2015.10.009_bib9","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1212\/WNL.52.3.640","article-title":"Long-chain L-3-hydroxyacyl-coenzyme A dehydrogenase deficiency neuropathy: response to cod liver oil","volume":"52","author":"Tein","year":"1999","journal-title":"Neurology"},{"key":"10.1016\/j.ejpn.2015.10.009_bib10","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0022-3476(97)70312-3","article-title":"Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency with the G1528C mutation: clinical presentation of thirteen patients","volume":"130","author":"Tyni","year":"1997","journal-title":"J Pediatr"},{"key":"10.1016\/j.ejpn.2015.10.009_bib11","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1023\/A:1005556207210","article-title":"Recognition and management of fatty acid oxidation defects: a series of 107 patients","volume":"22","author":"Saudubray","year":"1999","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.ejpn.2015.10.009_bib12","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1542\/peds.109.1.99","article-title":"Long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency: clinical presentation and follow-up of 50 patients","volume":"109","author":"den Boer","year":"2002","journal-title":"Pediatrics"},{"issue":"6","key":"10.1016\/j.ejpn.2015.10.009_bib13","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1067\/mpd.2003.231","article-title":"Mitochondrial trifunctional protein deficiency: a severe fatty acid oxidation disorder with cardiac and neurologic involvement","volume":"142","author":"den Boer","year":"2003","journal-title":"J Pediatr"},{"key":"10.1016\/j.ejpn.2015.10.009_bib14","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/mus.10500","article-title":"Peripheral neuropathy, episodic myoglobinuria, and respiratory failure in deficiency of the mitochondrial trifunctional protein","volume":"29","author":"Spiekerkoetter","year":"2004","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.ejpn.2015.10.009_bib15","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1007\/s10545-009-1125-9","article-title":"Management and outcome in 75 individuals with long-chain fatty acid oxidation defects: results from a workshop","volume":"32","author":"Spiekerkoetter","year":"2009","journal-title":"J Inherit Metab Dis"},{"issue":"79","key":"10.1016\/j.ejpn.2015.10.009_bib16","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S1096-7192(03)00073-8","article-title":"Optimal dietary therapy of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency","volume":"4","author":"Gillingham","year":"2003","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.ejpn.2015.10.009_bib17","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1007\/s10545-009-1126-8","article-title":"Treatment recommendations in long-chain fatty acid oxidation defects: consensus from a workshop","volume":"32","author":"Spiekerkoetter","year":"2009","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.ejpn.2015.10.009_bib18","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s10545-010-9188-1","article-title":"Current issues regarding treatment of mitochondrial fatty acid oxidation disorders","volume":"33","author":"Spiekerkoetter","year":"2010","journal-title":"J Inherit Metab Dis"},{"issue":"2","key":"10.1016\/j.ejpn.2015.10.009_bib19","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1212\/01.WNL.0000149522.32823.EA","article-title":"Distal symmetric polyneuropathy: a definition for clinical research. Report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation","volume":"64","author":"England","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.ejpn.2015.10.009_bib20","series-title":"Peripheral neuropathy in childhood","first-page":"29","author":"Ouvrier","year":"1999"},{"issue":"3","key":"10.1016\/j.ejpn.2015.10.009_bib21","doi-asserted-by":"crossref","first-page":"565","DOI":"10.2337\/diacare.25.3.565","article-title":"Carpal tunnel syndrome in patients with diabetic polyneuropathy","volume":"25","author":"Perkins","year":"2002","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ejpn.2015.10.009_bib22","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ymgme.2005.06.001","article-title":"Effect of optimal dietary therapy upon visual function in children with long-chain 3-hydroxyacyl CoA dehydrogenase and trifunctional protein deficiency","volume":"86","author":"Gillingham","year":"2005","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.ejpn.2015.10.009_bib23","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13023-015-0236-7","article-title":"Clinical outcome, biochemical and therapeutic follow-up in 14 Austrian patients with long-chain 3-hydroxy acyl CoA dehydrogenase deficiency (LCHADD)","volume":"10","author":"Karall","year":"2015","journal-title":"Orphanet J Rare Dis"}],"updated-by":[{"DOI":"10.1016\/j.ejpn.2017.12.001","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000}}],"container-title":["European Journal of Paediatric Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109037981500183X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109037981500183X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T11:55:52Z","timestamp":1748692552000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S109037981500183X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["S109037981500183X"],"URL":"https:\/\/doi.org\/10.1016\/j.ejpn.2015.10.009","relation":{"erratum":[{"id-type":"doi","id":"10.1016\/j.ejpn.2017.12.001","asserted-by":"object"}]},"ISSN":["1090-3798"],"issn-type":[{"value":"1090-3798","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Peripheral neuropathy in patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency \u2013 A follow-up EMG study of 12 patients","name":"articletitle","label":"Article Title"},{"value":"European Journal of Paediatric Neurology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejpn.2015.10.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}