{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T09:34:33Z","timestamp":1777887273181,"version":"3.51.4"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GTN117574"],"award-info":[{"award-number":["GTN117574"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["1144566"],"award-info":[{"award-number":["1144566"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001774","name":"University of Sydney","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004752","name":"State Government of Victoria","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004752","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012256","name":"Research Foundation of Cerebral Palsy Alliance","doi-asserted-by":"publisher","award":["CDF 0116"],"award-info":[{"award-number":["CDF 0116"]}],"id":[{"id":"10.13039\/100012256","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejpn-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Paediatric Neurology"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.ejpn.2022.01.019","type":"journal-article","created":{"date-parts":[[2022,2,6]],"date-time":"2022-02-06T01:08:31Z","timestamp":1644109711000},"page":"82-86","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The long-term burden of congenital cytomegalovirus: Hospitalisation and mortality in a population-based matched cohort study"],"prefix":"10.1016","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0082-2413","authenticated-orcid":false,"given":"Hayley","family":"Smithers-Sheedy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gulam","family":"Khandaker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camille","family":"Raynes-Greenow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lloyd","family":"Flack","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2993-6000","authenticated-orcid":false,"given":"Philip N.","family":"Britton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"McIntyre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Badawi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8304-4302","authenticated-orcid":false,"given":"David","family":"Burgner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Galea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl A.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejpn.2022.01.019_bib1","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1002\/rmv.655","article-title":"Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection","volume":"20","author":"Cannon","year":"2010","journal-title":"Rev. Med. Virol."},{"key":"10.1016\/j.ejpn.2022.01.019_bib2","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1128\/CVI.00203-06","article-title":"National serosurvey of cytomegalovirus in Australia","volume":"13","author":"Seale","year":"2006","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.ejpn.2022.01.019_bib3","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1128\/CMR.00062-12","article-title":"The \"silent\" global burden of congenital cytomegalovirus","volume":"26","author":"Manicklal","year":"2013","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.ejpn.2022.01.019_bib4","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1111\/jpc.12896","article-title":"Cytomegalovirus-related childhood mortality in Australia 1999-2011","volume":"51","author":"Smithers-Sheedy","year":"2015","journal-title":"J.\u00a0Paediatr. Child Health"},{"key":"10.1016\/j.ejpn.2022.01.019_bib5","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1471-2458-5-70","article-title":"Washing our hands of the congenital cytomegalovirus disease epidemic","volume":"5","author":"Cannon","year":"2005","journal-title":"BMC Publ. Health"},{"key":"10.1016\/j.ejpn.2022.01.019_bib6","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1002\/rmv.535","article-title":"Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection","volume":"17","author":"Kenneson","year":"2007","journal-title":"Rev. Med. Virol."},{"key":"10.1016\/j.ejpn.2022.01.019_bib7","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1440-1754.2005.00665.x","article-title":"Symptomatic infant characteristics of congenital cytomegalovirus disease in Australia","volume":"41","author":"Munro","year":"2005","journal-title":"J.\u00a0Paediatr. Child Health"},{"key":"10.1016\/j.ejpn.2022.01.019_bib8","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1093\/cid\/cit018","article-title":"Long-term outcomes of congenital cytomegalovirus infection in Sweden and the United Kingdom","volume":"56","author":"Townsend","year":"2013","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.ejpn.2022.01.019_bib9","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/rmv.544","article-title":"New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection","volume":"17","author":"Dollard","year":"2007","journal-title":"Rev. Med. Virol."},{"key":"10.1016\/j.ejpn.2022.01.019_bib10","doi-asserted-by":"crossref","first-page":"625","DOI":"10.5694\/j.1326-5377.2011.tb03144.x","article-title":"Congenital cytomegalovirus--time to diagnosis, management and clinical sequelae in Australia: opportunities for earlier identification","volume":"194","author":"McMullan","year":"2011","journal-title":"Med. J. Aust."},{"key":"10.1016\/j.ejpn.2022.01.019_bib11","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.jpeds.2015.10.069","article-title":"Symptomatic congenital cytomegalovirus infection is underdiagnosed in British Columbia","volume":"169","author":"Sorichetti","year":"2016","journal-title":"J.\u00a0Pediatr."},{"key":"10.1016\/j.ejpn.2022.01.019_bib12","series-title":"Census of Population and Housing: Socio-Economic Indexes for Areas (SEIFA), Australia","year":"2011"},{"key":"10.1016\/j.ejpn.2022.01.019_bib13","series-title":"Admitted Patient Data Collection","year":"2018"},{"key":"10.1016\/j.ejpn.2022.01.019_bib14","volume":"vol. 43","author":"Australian Institute of Health and Welfare","year":"2012"},{"key":"10.1016\/j.ejpn.2022.01.019_bib15","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.jpeds.2016.10.024","article-title":"Congenital cytomegalovirus among children with cerebral palsy","volume":"181","author":"Smithers-Sheedy","year":"2017","journal-title":"J.\u00a0Pediatr."},{"key":"10.1016\/j.ejpn.2022.01.019_bib16","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1136\/archdischild-2017-312805","article-title":"Healthcare costs attributable to congenital cytomegalovirus infection","volume":"103","author":"Korndewal","year":"2018","journal-title":"Arch. Dis. Child."},{"key":"10.1016\/j.ejpn.2022.01.019_bib17","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1097\/INF.0000000000000421","article-title":"Congenital cytomegalovirus-related hospitalizations in infants <1 year of age, United States, 1997-2009","volume":"33","author":"Lopez","year":"2014","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.ejpn.2022.01.019_bib18","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1471-2431-9-7","article-title":"Trends in hospitalizations for diagnosed congenital cytomegalovirus in infants and children in Australia","volume":"9","author":"Seale","year":"2009","journal-title":"BMC Pediatr."},{"key":"10.1016\/j.ejpn.2022.01.019_bib19","doi-asserted-by":"crossref","first-page":"239","DOI":"10.4161\/hv.4552","article-title":"The changing epidemiology of severe cytomegalovirus disease in Australia","volume":"3","author":"Seale","year":"2007","journal-title":"Hum. Vaccine"},{"key":"10.1016\/j.ejpn.2022.01.019_bib20","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1097\/00006454-199603000-00013","article-title":"Prevention of child-to-mother transmission of cytomegalovirus by changing behaviors: a randomized controlled trial","volume":"15","author":"Adler","year":"1996","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.ejpn.2022.01.019_bib21","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.ebiom.2015.08.003","article-title":"Prevention of primary cytomegalovirus infection in pregnancy","volume":"2","author":"Revello","year":"2015","journal-title":"EBioMedicine"},{"key":"10.1016\/j.ejpn.2022.01.019_bib22","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1097\/00006454-199108000-00008","article-title":"Cytomegalovirus and child day care: risk factors for maternal infection","volume":"10","author":"Adler","year":"1991","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.ejpn.2022.01.019_bib23","unstructured":"NSW Department of Health. Communicable diseases factsheet: cytomegalovirus (CMV) and pregnancy. In: Department of Health. (ed). NSW2013."},{"key":"10.1016\/j.ejpn.2022.01.019_bib24","series-title":"Clinical Practice Guidelines: Pregnancy Care","year":"2019"},{"key":"10.1016\/j.ejpn.2022.01.019_bib25","series-title":"Prevention of Congenital Cytomegalovirus (CMV) Infection the Royal Australian and New Zealand College of Obstetricians and Gynaecologists","author":"RANZCOG","year":"2019"},{"issue":"Suppl 4","key":"10.1016\/j.ejpn.2022.01.019_bib26","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1016\/j.jcv.2009.09.002","article-title":"Congenital cytomegalovirus (CMV) epidemiology and awareness","volume":"46","author":"Cannon","year":"2009","journal-title":"J.\u00a0Clin. Virol."},{"key":"10.1016\/j.ejpn.2022.01.019_bib27","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.ypmed.2012.03.009","article-title":"Awareness of and behaviors related to child-to-mother transmission of cytomegalovirus","volume":"54","author":"Cannon","year":"2012","journal-title":"Prev. Med."},{"issue":"Suppl 4","key":"10.1016\/j.ejpn.2022.01.019_bib28","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1016\/j.jcv.2009.09.006","article-title":"Awareness of congenital cytomegalovirus among doctors in The Netherlands","volume":"46","author":"Korver","year":"2009","journal-title":"J.\u00a0Clin. Virol."},{"key":"10.1016\/j.ejpn.2022.01.019_bib29","first-page":"1","article-title":"Cytomegalovirus (CMV) infection and pregnancy-potential for improvements in Australasian maternity health providers' knowledge","author":"Shand","year":"2017","journal-title":"J.\u00a0Matern. Fetal Neonatal Med."},{"key":"10.1016\/j.ejpn.2022.01.019_bib30","doi-asserted-by":"crossref","first-page":"291","DOI":"10.2174\/1871526518666181009093725","article-title":"Congenital cytomegalovirus prevention, awareness and policy recommendations - a scoping study","volume":"20","author":"Midgley","year":"2020","journal-title":"Infect. Disord. - Drug Targets"},{"key":"10.1016\/j.ejpn.2022.01.019_bib31","doi-asserted-by":"crossref","first-page":"e177","DOI":"10.1016\/S1473-3099(17)30143-3","article-title":"Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy","volume":"17","author":"Rawlinson","year":"2017","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ejpn.2022.01.019_bib32","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1056\/NEJMoa1404599","article-title":"Valganciclovir for symptomatic congenital cytomegalovirus disease","volume":"372","author":"Kimberlin","year":"2015","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.ejpn.2022.01.019_bib33","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.jpeds.2018.02.028","article-title":"Valganciclovir is beneficial in children with congenital cytomegalovirus and isolated hearing loss","volume":"199","author":"Pasternak","year":"2018","journal-title":"J.\u00a0Pediatr."},{"key":"10.1016\/j.ejpn.2022.01.019_bib34","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/ddrr.1106","article-title":"Cerebral palsy--don't delay","volume":"17","author":"McIntyre","year":"2011","journal-title":"Dev. Disabil. Res. Rev."},{"key":"10.1016\/j.ejpn.2022.01.019_bib35","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/mrdd.20051","article-title":"Prechtl's assessment of general movements: a diagnostic tool for the functional assessment of the young nervous system","volume":"11","author":"Einspieler","year":"2005","journal-title":"Ment. Retard. Dev. Disabil. Res. Rev."},{"key":"10.1016\/j.ejpn.2022.01.019_bib36","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/rmv.1790","article-title":"Universal newborn screening for congenital CMV infection: what is the evidence of potential benefit?","volume":"24","author":"Cannon","year":"2014","journal-title":"Rev. Med. Virol."},{"issue":"12","key":"10.1016\/j.ejpn.2022.01.019_bib37","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1001\/jamapediatrics.2016.2016","article-title":"Cost-effectiveness of universal and targeted newborn screening for congenital cytomegalovirus infection","volume":"170","author":"Gantt","year":"2016","journal-title":"JAMA Pediatr."},{"key":"10.1016\/j.ejpn.2022.01.019_bib38","doi-asserted-by":"crossref","first-page":"830","DOI":"10.3109\/09638288.2016.1161843","article-title":"A\u00a0combined surveillance program and quality register improves management of childhood disability","volume":"39","author":"Alriksson-Schmidt","year":"2017","journal-title":"Disabil. Rehabil."},{"key":"10.1016\/j.ejpn.2022.01.019_bib39","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/01202412-200507000-00007","article-title":"Prevention of severe contractures might replace multilevel surgery in cerebral palsy: results of a population-based health care programme and new techniques to reduce spasticity","volume":"14","author":"Hagglund","year":"2005","journal-title":"J.\u00a0Pediatr. Orthop. B"}],"container-title":["European Journal of Paediatric Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090379822000289?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090379822000289?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:06:50Z","timestamp":1777608410000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1090379822000289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":39,"alternative-id":["S1090379822000289"],"URL":"https:\/\/doi.org\/10.1016\/j.ejpn.2022.01.019","relation":{},"ISSN":["1090-3798"],"issn-type":[{"value":"1090-3798","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The long-term burden of congenital cytomegalovirus: Hospitalisation and mortality in a population-based matched cohort study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Paediatric Neurology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejpn.2022.01.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}