{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:37:57Z","timestamp":1780105077889,"version":"3.54.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,13]],"date-time":"2025-04-13T00:00:00Z","timestamp":1744502400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004374","name":"Medtronic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004374","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejpn-journal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Paediatric Neurology"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.ejpn.2025.04.002","type":"journal-article","created":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T21:22:38Z","timestamp":1744492958000},"page":"17-23","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["From childhood to adulthood: Long-term assessment of continuous intrathecal baclofen therapy in non-ambulant spastic cerebral palsy"],"prefix":"10.1016","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9714-3881","authenticated-orcid":false,"given":"B.H.M.","family":"Martens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Iskander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.L.","family":"Soudant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.F.","family":"Vles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.A.","family":"Bonouvri\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.P.M.","family":"Teernstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.S.H.","family":"Vles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3503-3625","authenticated-orcid":false,"given":"R.J.","family":"Vermeulen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ejpn.2025.04.002_bib1","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.ejpn.2008.04.013","article-title":"Efficacy of intrathecal baclofen therapy in children with intractable spastic cerebral palsy: a randomised controlled trial","volume":"13","author":"Hoving","year":"2009","journal-title":"Eur. J. Paediatr. Neurol."},{"issue":"1","key":"10.1016\/j.ejpn.2025.04.002_bib2","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ejpn.2009.05.002","article-title":"Consensus on the appropriate use of intrathecal baclofen (ITB) therapy in paediatric spasticity","volume":"14","author":"Dan","year":"2010","journal-title":"Eur. J. Paediatr. Neurol."},{"issue":"4","key":"10.1016\/j.ejpn.2025.04.002_bib3","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jspd.2013.05.002","article-title":"The relationship of gross motor functional classification scale level and hip dysplasia on the pattern and progression of scoliosis in children with cerebral palsy","volume":"1","author":"Garg","year":"2013","journal-title":"Spine Deformity"},{"issue":"2","key":"10.1016\/j.ejpn.2025.04.002_bib4","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1080\/01942630802031834","article-title":"Determinants of participation in leisure activities in children and youth with cerebral palsy: systematic review","volume":"28","author":"Shikako-Thomas","year":"2008","journal-title":"Phys. Occup. Ther. Pediatr."},{"key":"10.1016\/j.ejpn.2025.04.002_bib5","series-title":"Seminars in Pediatric Neurology","article-title":"The World Health Organization International Classification of Functioning, Disability, and Health: a model to guide clinical thinking, practice and research in the field of cerebral palsy","year":"2004"},{"issue":"3","key":"10.1016\/j.ejpn.2025.04.002_bib6","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1469-8749.2008.02031.x","article-title":"The relationship between quality of life and functioning for children with cerebral palsy","volume":"50","author":"Shelly","year":"2008","journal-title":"Dev. Med. Child Neurol."},{"issue":"12","key":"10.1016\/j.ejpn.2025.04.002_bib7","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0165-6147(96)01013-9","article-title":"GABA and its receptors in the spinal cord","volume":"17","author":"Melcangic","year":"1996","journal-title":"Trends Pharmacol. Sci."},{"issue":"3","key":"10.1016\/j.ejpn.2025.04.002_bib8","doi-asserted-by":"crossref","first-page":"193","DOI":"10.2340\/16501977-2211","article-title":"Efficacy and safety of oral baclofen in the management of spasticity: a rationale for intrathecal baclofen","volume":"49","author":"Ertzgaard","year":"2017","journal-title":"J. Rehabil. Med."},{"issue":"3","key":"10.1016\/j.ejpn.2025.04.002_bib9","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/dmcn.14088","article-title":"Management of pain in children and adolescents with cerebral palsy: a systematic review","volume":"61","author":"Ostojic","year":"2019","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.ejpn.2025.04.002_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11910-020-1022-z","article-title":"State of the evidence traffic lights 2019: systematic review of interventions for preventing and treating children with cerebral palsy","volume":"20","author":"Novak","year":"2020","journal-title":"Curr. Neurol. Neurosci. Rep."},{"issue":"6","key":"10.1016\/j.ejpn.2025.04.002_bib11","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.ejpn.2013.06.003","article-title":"Long-term follow-up on continuous intrathecal Baclofen therapy in non-ambulant children with intractable spastic Cerebral Palsy","volume":"17","author":"Vles","year":"2013","journal-title":"Eur. J. Paediatr. Neurol."},{"issue":"4","key":"10.1016\/j.ejpn.2025.04.002_bib12","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/nur.4770130405","article-title":"A critical review of visual analogue scales in the measurement of clinical phenomena","volume":"13","author":"Wewers","year":"1990","journal-title":"Res. Nurs. Health"},{"key":"10.1016\/j.ejpn.2025.04.002_bib13","series-title":"The CHQ User's Manual","author":"Landgraf","year":"1996"},{"issue":"2\u20133 Pt 2","key":"10.1016\/j.ejpn.2025.04.002_bib14","first-page":"339","article-title":"Surgical treatment of orthopedic deformities due to spasticity in the lower limb","volume":"49","author":"Denormandie","year":"2003","journal-title":"Neurochirurgie"},{"issue":"4","key":"10.1016\/j.ejpn.2025.04.002_bib15","first-page":"345","article-title":"Management of spasticity in children with cerebral palsy","volume":"24","author":"Shamsoddini","year":"2014","journal-title":"Iran. J. Pediatr. (Engl. Ed.)"},{"issue":"5","key":"10.1016\/j.ejpn.2025.04.002_bib16","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/j.2048-7940.2003.tb02050.x","article-title":"A self\u2010report of quality of life of patients receiving intrathecal baclofen therapy","volume":"28","author":"Staal","year":"2003","journal-title":"Rehabil. Nurs."},{"issue":"2","key":"10.1016\/j.ejpn.2025.04.002_bib17","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/dmcn.14005","article-title":"Effect of continuous intrathecal baclofen therapy in children: a systematic review","volume":"61","author":"Buizer","year":"2019","journal-title":"Dev. Med. Child Neurol."},{"issue":"1","key":"10.1016\/j.ejpn.2025.04.002_bib18","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/dmcn.13625","article-title":"Intrathecal baclofen in dyskinetic cerebral palsy: effects on function and activity","volume":"60","author":"Eek","year":"2018","journal-title":"Dev. Med. Child Neurol."},{"issue":"1","key":"10.1016\/j.ejpn.2025.04.002_bib19","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/ana.25498","article-title":"The effect of intrathecal baclofen in dyskinetic cerebral palsy: the IDYS trial","volume":"86","author":"Bonouvri\u00e9","year":"2019","journal-title":"Ann. Neurol."},{"issue":"4","key":"10.1016\/j.ejpn.2025.04.002_bib20","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1053\/apmr.2003.50030","article-title":"Oral motor, communication, and nutritional status of children during intrathecal baclofen therapy: a descriptive pilot study","volume":"84","author":"Bjornson","year":"2003","journal-title":"Arch. Phys. Med. Rehabil."},{"key":"10.1016\/j.ejpn.2025.04.002_bib21","doi-asserted-by":"crossref","first-page":"e550","DOI":"10.1016\/j.wneu.2019.02.092","article-title":"Intrathecal baclofen pump versus globus pallidus interna deep brain stimulation in adult patients with severe cerebral palsy","volume":"126","author":"Kim","year":"2019","journal-title":"World Neurosur."},{"issue":"1","key":"10.1016\/j.ejpn.2025.04.002_bib22","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/dmcn.13555","article-title":"The prevalence of mental health disorders and symptoms in children and adolescents with cerebral palsy: a systematic review and meta\u2010analysis","volume":"60","author":"Downs","year":"2018","journal-title":"Dev. Med. Child Neurol."},{"issue":"6","key":"10.1016\/j.ejpn.2025.04.002_bib23","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/j.apmr.2013.12.019","article-title":"Occurrence of adverse events in long-term intrathecal baclofen infusion: a 1-year follow-up study of 158 adults","volume":"95","author":"Borrini","year":"2014","journal-title":"Arch. Phys. Med. Rehabil."},{"issue":"5","key":"10.1016\/j.ejpn.2025.04.002_bib24","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.965","article-title":"Eleven years' experience with intrathecal baclofen\u2013complications, risk factors","volume":"8","author":"Pucks\u2010Faes","year":"2018","journal-title":"Brain Behavior"},{"issue":"3","key":"10.1016\/j.ejpn.2025.04.002_bib25","doi-asserted-by":"crossref","first-page":"301","DOI":"10.3171\/2013.11.PEDS13253","article-title":"Analysis of complications in 430 consecutive pediatric patients treated with intrathecal baclofen therapy: 14-year experience","volume":"13","author":"Motta","year":"2014","journal-title":"J. Neurosurg. Pediatr."},{"issue":"1","key":"10.1016\/j.ejpn.2025.04.002_bib26","doi-asserted-by":"crossref","first-page":"11","DOI":"10.5535\/arm.22108","article-title":"Effect of intrathecal baclofen pump on scoliosis in children with cerebral palsy: a meta-analysis","volume":"47","author":"Lee","year":"2023","journal-title":"Annals Rehabilitation Med."},{"issue":"6","key":"10.1016\/j.ejpn.2025.04.002_bib27","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1111\/dmcn.15120","article-title":"Life expectancy and its adjustment in cerebral palsy with severe impairment: are we doing this right?","volume":"64","author":"Rosenthal","year":"2022","journal-title":"Dev. Med. Child Neurol."},{"issue":"4","key":"10.1016\/j.ejpn.2025.04.002_bib28","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3171\/2012.6.PEDS11456","article-title":"Intraventricular baclofen as an alternative to intrathecal baclofen for intractable spasticity or dystonia: outcomes and technical considerations","volume":"10","author":"Turner","year":"2012","journal-title":"J. Neurosurg. Pediatr."},{"issue":"aop","key":"10.1016\/j.ejpn.2025.04.002_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2024.10.PEDS24228","article-title":"Intraventricular baclofen for the treatment of pediatric spasticity in cerebral palsy: technique and outcomes","volume":"1","author":"Piazza","year":"2025","journal-title":"J. Neurosurg. Pediatr."}],"container-title":["European Journal of Paediatric Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090379825000509?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090379825000509?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T15:22:52Z","timestamp":1748877772000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1090379825000509"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":29,"alternative-id":["S1090379825000509"],"URL":"https:\/\/doi.org\/10.1016\/j.ejpn.2025.04.002","relation":{},"ISSN":["1090-3798"],"issn-type":[{"value":"1090-3798","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"From childhood to adulthood: Long-term assessment of continuous intrathecal baclofen therapy in non-ambulant spastic cerebral palsy","name":"articletitle","label":"Article Title"},{"value":"European Journal of Paediatric Neurology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejpn.2025.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of European Paediatric Neurology Society.","name":"copyright","label":"Copyright"}]}}