{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T10:15:54Z","timestamp":1717582554027},"reference-count":40,"publisher":"Elsevier BV","issue":"4-5","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.ejps.2008.05.008","type":"journal-article","created":{"date-parts":[[2008,6,6]],"date-time":"2008-06-06T08:41:18Z","timestamp":1212741678000},"page":"321-332","source":"Crossref","is-referenced-by-count":10,"title":["Modeling of flux through silicone membranes from water"],"prefix":"10.1016","volume":"34","author":[{"given":"Scott","family":"Wasdo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juha","family":"Juntunen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hema","family":"Devarajan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Murray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna","family":"Nickels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surjit","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thea","family":"Shanks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Ulmer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth B.","family":"Sloan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejps.2008.05.008_bib1","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1002\/jps.20070","article-title":"Human skin permeation and partition: general linear free-energy relationships analysis","volume":"93","author":"Abraham","year":"2004","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib2","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/1523-1747.ep12277592","article-title":"Solute structure\u2013permeability relationships in human stratum corneum","volume":"93","author":"Anderson","year":"1989","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ejps.2008.05.008_bib3","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0378-5173(96)89422-1","article-title":"Prediction of flux through polydimethylsiloxane membrane using atomic charge calculations: application to an extended data set","volume":"137","author":"Chen","year":"1996","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ejps.2008.05.008_bib4","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1111\/j.2042-7158.1998.tb06169.x","article-title":"An investigation of the mechanism of flux across polydimethylsiloxane membranes by use of quantitative\u2013structure\u2013permeability relationships","volume":"50","author":"Cronin","year":"1998","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.ejps.2008.05.008_bib5","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0928-0987(98)00041-4","article-title":"Investigation of flux across human skin in vitro by quantitative structure\u2013permeability relationships","volume":"7","author":"Cronin","year":"1999","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib6","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1467-2494.1996.tb00135.x","article-title":"Percutaneous absorption of parabens from cosmetic formulations","volume":"18","author":"Dal Pozzo","year":"1996","journal-title":"Int. J. Cosmet."},{"key":"10.1016\/j.ejps.2008.05.008_bib7","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.ijpharm.2006.11.054","article-title":"Influence of membrane\u2013solvent\u2013solute interactions on solute permeation in model membranes","volume":"336","author":"Diaz","year":"2007","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ejps.2008.05.008_bib8","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1002\/jps.2600610603","article-title":"Correlation and prediction of mass transport across membranes. I. Influence of alkyl chain length on flux-determining properties of barrier and diffusant","volume":"61","author":"Flynn","year":"1972","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib9","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1023\/A:1020745026766","article-title":"Quantitative structure\u2013permeation relationships for solute transport across silicone membranes","volume":"19","author":"Geinoz","year":"2002","journal-title":"Pharm. Res."},{"key":"10.1016\/j.ejps.2008.05.008_bib10","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1248\/cpb.38.3452","article-title":"Prediction of skin permeability of drugs. I. Comparison with artificial membrane","volume":"38","author":"Hatanaka","year":"1990","journal-title":"Chem. Pharm. Bull."},{"key":"10.1016\/j.ejps.2008.05.008_bib11","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1021\/js960198e","article-title":"Evaluation of solute permeation through the stratum corneum: lateral bilayer diffusion as the primary transport mechanism","volume":"86","author":"Johnson","year":"1997","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib12","first-page":"138","article-title":"Effect of lipid solubility and molecular size on percutaneous absorption","volume":"vol. 1","author":"Kasting","year":"1987"},{"key":"10.1016\/j.ejps.2008.05.008_bib13","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1002\/qsar.200510219","article-title":"QSAR Prediction of the penetration of drugs across a polydimethylsiloxane membrane","volume":"25","author":"Ma","year":"2006","journal-title":"QSAR Comb. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib14","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1111\/j.0022-202X.2004.22413.x","article-title":"Molecular size as the main determinant of solute maximum flux across the skin","volume":"122","author":"Magnusson","year":"2004","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ejps.2008.05.008_bib15","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.ijpharm.2006.08.015","article-title":"The effect of water solubility of solutes on their flux through human skin in vitro","volume":"329","author":"Majumdar","year":"2007","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ejps.2008.05.008_bib16","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/aic.690210522","article-title":"Drug permeation through human skin: theory and in vitro experimental measurement","volume":"21","author":"Michaels","year":"1975","journal-title":"Am. Inst. Chem. Eng."},{"key":"10.1016\/j.ejps.2008.05.008_bib17","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1211\/jpp.58.2.0003","article-title":"Design, synthesis and characterization of captopril prodrugs for enhanced percutaneous absorption","volume":"58","author":"Moss","year":"2006","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.ejps.2008.05.008_bib18","doi-asserted-by":"crossref","first-page":"3948","DOI":"10.1021\/jm060230+","article-title":"Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability","volume":"49","author":"Ottaviani","year":"2006","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.ejps.2008.05.008_bib19","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1021\/jm0611105","article-title":"In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities","volume":"50","author":"Ottaviani","year":"2007","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.ejps.2008.05.008_bib20","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0378-5173(97)00142-7","article-title":"Comparison of permeability data from traditional diffusion cells and ATR\u2013FTIR spectroscopy. Part I. Synthetic membranes","volume":"154","author":"Pellett","year":"1997","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ejps.2008.05.008_bib21","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1023\/A:1015810312465","article-title":"Predicting skin permeability","volume":"9","author":"Potts","year":"1992","journal-title":"Pharm. Res."},{"key":"10.1016\/j.ejps.2008.05.008_bib22","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1021\/js980419b","article-title":"Correlation of aqueous and lipid solubilities with flux for prodrugs of 5-fluorouracil, theophylline and 6-mercaptopurine: a Potts\u2013Guy approach","volume":"88","author":"Roberts","year":"1999","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib23","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1002\/1520-6017(200011)89:11<1415::AID-JPS5>3.0.CO;2-T","article-title":"Prediction of transdermal flux of prodrugs of 5-fluorouracil, theophylline and 6-mercaptopurine with a series\/parallel model","volume":"89","author":"Roberts","year":"2000","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib24","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1002\/jps.1084","article-title":"Application of the transformed Potts\u2013Guy equation to in vivo human skin data","volume":"90","author":"Roberts","year":"2001","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib25","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1002\/jhet.5570390509","article-title":"Synthesis of 3-alkylcarbonyloxymethyl derivatives of 5-fluorouracil","volume":"39","author":"Roberts","year":"2002","journal-title":"J. Heterocycl. Chem."},{"key":"10.1016\/j.ejps.2008.05.008_bib26","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1111\/1523-1747.ep12723090","article-title":"Mechanism of percutaneous absorption. IV. Penetration of nonelectrolytes (alcohols) from aqueous solutions and pure liquids","volume":"60","author":"Scheuplein","year":"1973","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ejps.2008.05.008_bib27","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/0378-5173(84)90184-4","article-title":"Mannich base derivatives of theophylline and 5-fluorouracil: syntheses, properties and topical delivery characteristics","volume":"21","author":"Sloan","year":"1984","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ejps.2008.05.008_bib28","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/1523-1747.ep12696635","article-title":"The use of solubility parameters of drug and vehicle to predict flux","volume":"87","author":"Sloan","year":"1986","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ejps.2008.05.008_bib29","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/0169-409X(89)90005-7","article-title":"Prodrugs for dermal delivery","volume":"3","author":"Sloan","year":"1989","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.ejps.2008.05.008_bib30","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1023\/A:1023207118209","article-title":"Topical delivery of 5-fluorouracil and 6-mercaptopurine by their alkylcarbonyloxymethyl prodrugs from water: vehicle effects on design of prodrugs","volume":"20","author":"Sloan","year":"2003","journal-title":"Pharm. Res."},{"key":"10.1016\/j.ejps.2008.05.008_bib31","doi-asserted-by":"crossref","first-page":"2729","DOI":"10.1007\/s11095-006-9108-0","article-title":"Design for optimized topical delivery: prodrugs and a paradigm change","volume":"23","author":"Sloan","year":"2006","journal-title":"Pharm. Res."},{"key":"10.1016\/j.ejps.2008.05.008_bib32","series-title":"Prodrugs: challenges and rewards. Part 1","first-page":"83","article-title":"Topical delivery using prodrugs","author":"Sloan","year":"2007"},{"key":"10.1016\/j.ejps.2008.05.008_bib33","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.ijpharm.2007.02.031","article-title":"The effect of water solubility of solutes on their flux through human skin in vitro: an extended Flynn database fitted to the Roberts\u2013Sloan equation","volume":"339","author":"Thomas","year":"2007","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ejps.2008.05.008_bib34","first-page":"429","article-title":"Influence of solvents on paraben permeation through idealized model membranes","volume":"37","author":"Twist","year":"1986","journal-title":"J. Soc. Cosmet. Chem."},{"key":"10.1016\/j.ejps.2008.05.008_bib35","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1002\/jps.2600770616","article-title":"Membrane\u2013solvent\u2013solute interaction in a model permeation system","volume":"77","author":"Twist","year":"1988","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib36","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/jps.2600790108","article-title":"A model for alcohol-enhanced permeation through polydimethylsiloxane membranes","volume":"79","author":"Twist","year":"1990","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib37","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1023\/B:PHAM.0000029281.12753.25","article-title":"Topical delivery of a model phenolic drug: alkylcarbonyl prodrugs of acetaminophen","volume":"21","author":"Wasdo","year":"2004","journal-title":"Pharm. Res."},{"key":"10.1016\/j.ejps.2008.05.008_bib38","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1002\/jps.2600760803","article-title":"The effect of vehicle and prodrug properties and their interactions on the delivery of 6-mercaptopurine through skin: bisacyloxymethyl-6-mercaptopurine prodrugs","volume":"76","author":"Waranis","year":"1987","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib39","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/jps.2600770306","article-title":"Effects of vehicles and prodrug properties and their interactions on the delivery of 6-mercaptopurine through skin: S6-acyloxymethyl-6-mercaptopurine prodrugs","volume":"77","author":"Waranis","year":"1988","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2008.05.008_bib40","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/0045-6535(95)00023-2","article-title":"Estimating skin permeation. The validation of five mathematical skin permeation models","volume":"30","author":"Wilschut","year":"1995","journal-title":"Chemosphere"}],"container-title":["European Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928098708002820?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928098708002820?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T01:28:34Z","timestamp":1545960514000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0928098708002820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":40,"journal-issue":{"issue":"4-5","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["S0928098708002820"],"URL":"https:\/\/doi.org\/10.1016\/j.ejps.2008.05.008","relation":{},"ISSN":["0928-0987"],"issn-type":[{"value":"0928-0987","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}