{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T01:28:30Z","timestamp":1790904510554,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:00:00Z","timestamp":1698710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pharmaceutical Sciences"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.ejps.2023.106629","type":"journal-article","created":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T14:10:07Z","timestamp":1698934207000},"page":"106629","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Novel nanomicelle butenafine formulation for ocular drug delivery against fungal keratitis: In Vitro and In Vivo study"],"prefix":"10.1016","volume":"192","author":[{"given":"Ping","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingguo","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejps.2023.106629_bib0001","doi-asserted-by":"crossref","first-page":"698","DOI":"10.3389\/fcimb.2021.698780","article-title":"Distribution, prevalence, and causative agents of fungal keratitis: a systematic review and meta-analysis (1990 to 2020)","volume":"11","author":"Ahmadikia","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.ejps.2023.106629_bib0002","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.jsps.2021.04.010","article-title":"Formulation and in vitro evaluation of topical nanosponge-based gel containing butenafine for the treatment of fungal skin infection","volume":"29","author":"Ahmed","year":"2021","journal-title":"Saudi Pharm. J"},{"key":"10.1016\/j.ejps.2023.106629_bib0003","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0226639","article-title":"Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene","volume":"14","author":"Alhakamy","year":"2019","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ejps.2023.106629_bib0004","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.mimet.2019.01.020","article-title":"Antifungal efficacy of Itraconazole loaded PLGA-nanoparticles stabilized by vitamin-E TPGS: in vitro and ex vivo studies","volume":"161","author":"Alhowyan","year":"2019","journal-title":"J. Microbiol. Methods"},{"key":"10.1016\/j.ejps.2023.106629_bib0005","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1080\/02652048.2020.1761904","article-title":"Development of folic acid-loaded nanostructured lipid carriers for topical delivery: preparation, characterisation and ex vivo investigation","volume":"37","author":"Ammar","year":"2020","journal-title":"J. Microencapsul."},{"key":"10.1016\/j.ejps.2023.106629_bib0006","doi-asserted-by":"crossref","first-page":"4205","DOI":"10.1111\/bph.14024","article-title":"Principles of pharmacology in the eye","volume":"174","author":"Awwad","year":"2017","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ejps.2023.106629_bib0007","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.jconrel.2011.04.019","article-title":"A method for enhancing the ocular penetration of eye drops using nanoparticles of hydrolyzable dye","volume":"153","author":"Baba","year":"2011","journal-title":"J. Control Rel."},{"key":"10.1016\/j.ejps.2023.106629_bib0008","first-page":"861","article-title":"Ophthalmic drug dosage forms: characterisation and research methods","author":"Baranowski","year":"2014","journal-title":"Sci. World J."},{"key":"10.1016\/j.ejps.2023.106629_bib0009","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3390\/pharmaceutics11070353","article-title":"Repurposing butenafine as an oral nanomedicine for visceral leishmaniasis","volume":"11","author":"Bezerra-Souza","year":"2019","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.ejps.2023.106629_bib0010","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/8828750","article-title":"Nanoemulsified butenafine for enhanced performance against experimental cutaneous leishmaniasis","volume":"2021","author":"Bezerra-Souza","year":"2021","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.ejps.2023.106629_bib0011","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S1473-3099(20)30448-5","article-title":"The global incidence and diagnosis of fungal keratitis","volume":"21","author":"Brown","year":"2021","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ejps.2023.106629_bib0012","doi-asserted-by":"crossref","first-page":"642","DOI":"10.3390\/pharmaceutics12070642","article-title":"A novel vitamin E TPGS-based formulation enhances chlorhexidine bioavailability in corneal layers","volume":"12","author":"Caruso","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.ejps.2023.106629_bib0013","first-page":"4409","article-title":"Development of terbinafine solid lipid nanoparticles as a topical delivery system","volume":"7","author":"Chen","year":"2012","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.ejps.2023.106629_bib0014","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1080\/01932690008913270","article-title":"Using electrophoresis to determine zeta potential of micelles and critical micelle concentration","volume":"21","author":"Chiu","year":"2000","journal-title":"J. Dispers Sci. Technol."},{"key":"10.1016\/j.ejps.2023.106629_bib0015","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1208\/s12249-014-0244-2","article-title":"Nanomicellar topical aqueous drop formulation of rapamycin for Back-of-the-Eye delivery","volume":"16","author":"Cholkar","year":"2015","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.ejps.2023.106629_bib0016","doi-asserted-by":"crossref","first-page":"314","DOI":"10.2174\/2211738507666190726162000","article-title":"A novel approach of drug localization through development of polymeric micellar system containing azelastine HCl for ocular delivery","volume":"7","author":"Devi","year":"2019","journal-title":"Pharmaceutic. Nanotechnol."},{"key":"10.1016\/j.ejps.2023.106629_bib0017","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1089\/jop.2019.0109","article-title":"Micelles: promising ocular drug carriers for anterior and posterior segment diseases","volume":"36","author":"Durgun","year":"2020","journal-title":"J. Ocul. Pharmacol. Ther."},{"key":"10.1016\/j.ejps.2023.106629_bib0018","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/304757","article-title":"A review of in vitro drug release test methods for nano-sized dosage forms","volume":"2014","author":"Susan","year":"2014","journal-title":"Adv. Pharmaceut."},{"key":"10.1016\/j.ejps.2023.106629_bib0019","doi-asserted-by":"crossref","first-page":"7748","DOI":"10.1021\/jacs.1c02147","article-title":"Molecular weight dependence of block copolymer micelle fragmentation kinetics","volume":"143","author":"Early","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.ejps.2023.106629_bib0020","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1208\/s12248-010-9183-3","article-title":"Ocular drug delivery","volume":"12","author":"Gaudana","year":"2010","journal-title":"AAPS J."},{"key":"10.1016\/j.ejps.2023.106629_bib0021","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.jconrel.2021.02.031","article-title":"Polymeric micelles in drug delivery: an insight of the techniques for their characterization and assessment in biorelevant conditions","volume":"332","author":"Ghezzi","year":"2021","journal-title":"J. Controll. Rel.: Off. J. Controll. Rel. Soc."},{"key":"10.1016\/j.ejps.2023.106629_bib0022","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1080\/17425255.2020.1803278","article-title":"Prodrugs and nanomicelles to overcome ocular barriers for drug penetration","volume":"16","author":"Gote","year":"2020","journal-title":"Expert Opin. Drug Metab. Toxicol."},{"key":"10.1016\/j.ejps.2023.106629_bib0023","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1124\/jpet.119.256933","article-title":"Ocular drug delivery: present innovations and future challenges","volume":"370","author":"Gote","year":"2019","journal-title":"J. Pharmacol. Exp. Therapeut."},{"key":"10.1016\/j.ejps.2023.106629_bib0024","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1021\/acs.molpharmaceut.7b00939","article-title":"Poloxamer 407\/TPGS mixed micelles as promising carriers for cyclosporine ocular delivery","volume":"15","author":"Grimaudo","year":"2018","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.ejps.2023.106629_bib0025","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.ejps.2013.02.006","article-title":"The applications of Vitamin E TPGS in drug delivery","volume":"49","author":"Guo","year":"2013","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2023.106629_bib0026","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/j.xphs.2019.01.016","article-title":"The role of surface active agents in ophthalmic drug delivery: a comprehensive review","volume":"108","author":"Ibrahim","year":"2019","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2023.106629_bib0027","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jconrel.2020.01.057","article-title":"Advances and limitations of drug delivery systems formulated as eye drops","volume":"321","author":"Jumelle","year":"2020","journal-title":"J. Control Rel."},{"key":"10.1016\/j.ejps.2023.106629_bib0028","doi-asserted-by":"crossref","DOI":"10.1002\/ardp.201600342","article-title":"Synthesis and structure-activity relationships of novel benzylamine-type antifungals as butenafine-related antimycotics","volume":"350","author":"Krauss","year":"2017","journal-title":"Arch. Pharm. (Weinheim)"},{"key":"10.1016\/j.ejps.2023.106629_bib0029","doi-asserted-by":"crossref","first-page":"103","DOI":"10.22159\/ijap.2021v13i1.39925","article-title":"Study of isotonicity and ocular irritation of chloramphenicol in situ gel","volume":"13","author":"Kurniawansyah","year":"2021","journal-title":"Int. J. Appl. Pharmaceut."},{"key":"10.1016\/j.ejps.2023.106629_bib0030","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1080\/10717544.2018.1461278","article-title":"Fabrication of a drug delivery system that enhances antifungal drug corneal penetration","volume":"25","author":"Li","year":"2018","journal-title":"Drug Deliv."},{"key":"10.1016\/j.ejps.2023.106629_bib0031","doi-asserted-by":"crossref","first-page":"6027","DOI":"10.2147\/IJN.S90347","article-title":"Positively charged micelles based on a triblock copolymer demonstrate enhanced corneal penetration","volume":"10","author":"Li","year":"2015","journal-title":"Int J Nanomedicine"},{"key":"10.1016\/j.ejps.2023.106629_bib0032","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1080\/10408347008542734","article-title":"Phase solubility analysis","volume":"1","author":"Mader","year":"1970","journal-title":"C R C Crit. Rev. Anal. Chem."},{"key":"10.1016\/j.ejps.2023.106629_bib0033","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.3390\/pharmaceutics13071087","article-title":"Formulation and optimization of butenafine-loaded topical nano lipid carrier-based gel: characterization, irritation study, and anti-fungal activity","volume":"13","author":"Mahdi","year":"2021","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.ejps.2023.106629_bib0034","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1208\/s12249-018-1267-x","article-title":"Multi-Layered Nanomicelles as Self-Assembled Nanocarrier Systems for Ocular Peptide Delivery","volume":"20","author":"Mandal","year":"2019","journal-title":"AAPS PharmSciTech"},{"key":"10.1016\/j.ejps.2023.106629_bib0035","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.3390\/pharmaceutics13071087","article-title":"Formulation and optimization of butenafine-loaded topical nano lipid carrier-based gel: characterization, irritation study, and anti-fungal activity","volume":"13","author":"Mahdi","year":"2021","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.ejps.2023.106629_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2020.108372","article-title":"The role of fungi in fungal keratitis","volume":"202","author":"Mills","year":"2021","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.ejps.2023.106629_bib0037","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1089\/jop.2012.0241","article-title":"Anterior eye segment drug delivery systems: current treatments and future challenges","volume":"29","author":"Molokhia","year":"2013","journal-title":"J. Ocul. Pharmacol. Ther."},{"key":"10.1016\/j.ejps.2023.106629_bib0038","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1111\/jphp.12924","article-title":"Delivery of therapeutics for deep-seated ocular conditions \u2013 status quo","volume":"70","author":"Nguyen","year":"2018","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.ejps.2023.106629_bib0039","first-page":"320","article-title":"Automated quantification of keratocyte density by using confocal microscopy in vivo","volume":"40","author":"Patel","year":"1999","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ejps.2023.106629_bib0040","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1016\/j.xphs.2018.04.014","article-title":"Formulation development, optimization, and In Vitro-In Vivo characterization of natamycin-loaded PEGylated Nano-Lipid carriers for ocular applications","volume":"107","author":"Patil","year":"2018","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.ejps.2023.106629_bib0041","first-page":"1038","article-title":"Ocular pharmacokinetics of topical administration of butenafine nanomicelles in rabbit eyes","volume":"38","author":"Ping","year":"2020","journal-title":"Chin. J. Exp. Ophthalmol."},{"key":"10.1016\/j.ejps.2023.106629_bib0042","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.jare.2018.06.004","article-title":"Butenafine and analogues: an expeditious synthesis and cytotoxicity and antifungal activities","volume":"14","author":"Porras","year":"2018","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.ejps.2023.106629_bib0043","doi-asserted-by":"crossref","first-page":"907","DOI":"10.3390\/jof7110907","article-title":"Recent perspectives in the management of fungal keratitis","volume":"7","author":"Raj","year":"2021","journal-title":"J. Fungi (Basel)"},{"key":"10.1016\/j.ejps.2023.106629_bib0044","first-page":"1","article-title":"Formulation, optimization and evaluation of microemulsion based gel of Butenafine Hydrochloride for topical delivery by using simplex lattice mixture design","volume":"46","author":"Rao","year":"2015","journal-title":"J. Pharmaceut. Invest."},{"key":"10.1016\/j.ejps.2023.106629_bib0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijpharm.2020.120045","article-title":"Nanocarriers based on vitamin E-TPGS: design principle and molecular insights into improving the efficacy of anticancer drugs","volume":"592","author":"Rathod","year":"2021","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ejps.2023.106629_bib0046","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s10895-018-2209-4","article-title":"Determination of the critical micelle concentration of neutral and ionic surfactants with fluorometry, conductometry, and surface tension\u2014a method comparison","volume":"28","author":"Scholz","year":"2018","journal-title":"J. Fluoresc."},{"key":"10.1016\/j.ejps.2023.106629_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2021.118762","article-title":"A dual-functional chitosan derivative platform for fungal keratitis","volume":"275","author":"Shi","year":"2022","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ejps.2023.106629_bib0048","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1080\/10717544.2019.1622608","article-title":"New micelle myricetin formulation for ocular delivery: improved stability, solubility, and ocular anti-inflammatory treatment","volume":"26","author":"Sun","year":"2019","journal-title":"Drug Deliv."},{"key":"10.1016\/j.ejps.2023.106629_bib0049","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1080\/10717544.2019.1692966","article-title":"Preparation and study of two kinds of ophthalmic nano-preparations of everolimus","volume":"26","author":"Tang","year":"2019","journal-title":"Drug Deliv."},{"key":"10.1016\/j.ejps.2023.106629_bib0050","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1089\/jop.2013.0157","article-title":"Aqueous nanomicellar formulation for topical delivery of biotinylated lipid prodrug of acyclovir: formulation development and ocular biocompatibility","volume":"30","author":"Vadlapudi","year":"2014","journal-title":"J. Ocul. Pharmacol. Ther."},{"key":"10.1016\/j.ejps.2023.106629_bib0051","doi-asserted-by":"crossref","first-page":"7195","DOI":"10.1021\/acsnano.5b02017","article-title":"The role of micelle size in tumor accumulation, penetration, and treatment","volume":"9","author":"Wang","year":"2015","journal-title":"ACS Nano"},{"key":"10.1016\/j.ejps.2023.106629_bib0052","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S0039-6257(01)00211-9","article-title":"The draize eye test","volume":"45","author":"Wilhelmus","year":"2001","journal-title":"Surv. Ophthalmol."},{"key":"10.1016\/j.ejps.2023.106629_bib0053","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1167\/iovs.02-0446","article-title":"Experimental keratomycosis in a mouse model","volume":"44","author":"Wu","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ejps.2023.106629_bib0054","first-page":"38","article-title":"Activity of butenafine against ocular pathogenic filamentous fungi in vitro","volume":"46","author":"Yan","year":"2010","journal-title":"Chin. J. Exp. Ophthalmol."},{"key":"10.1016\/j.ejps.2023.106629_bib0055","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.2147\/IJN.S360740","article-title":"Dual drug loaded lipid nanocarrier formulations for topical ocular applications","volume":"17","author":"Youssef","year":"2022","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.ejps.2023.106629_bib0056","doi-asserted-by":"crossref","first-page":"591","DOI":"10.2147\/IJN.S179118","article-title":"High drug payload nanoparticles formed from dexamethasone-peptide conjugates for the treatment of endotoxin-induced uveitis in rabbit","volume":"14","author":"Yu","year":"2019","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.ejps.2023.106629_bib0057","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1080\/10717544.2018.1458923","article-title":"Improving the topical ocular pharmacokinetics of lyophilized cyclosporine A-loaded micelles: formulation, in vitro and in vivo studies","volume":"25","author":"Yu","year":"2018","journal-title":"Drug Deliv."},{"key":"10.1016\/j.ejps.2023.106629_bib0058","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.exer.2013.03.002","article-title":"A novel murine model of Fusarium solani keratitis utilizing fluorescent labeled fungi","volume":"110","author":"Zhang","year":"2013","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.ejps.2023.106629_bib0059","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1089\/jop.2017.0139","article-title":"Comparison of the ocular penetration and pharmacokinetics between natamycin and voriconazole after topical instillation in rabbits","volume":"34","author":"Zhao","year":"2018","journal-title":"J. Ocular Pharmacol. Therapeut."},{"key":"10.1016\/j.ejps.2023.106629_bib0060","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.ejps.2017.08.020","article-title":"Micelle carriers based on macrogol 15 hydroxystearate for ocular delivery of terbinafine hydrochloride: in vitro characterization and in vivo permeation","volume":"109","author":"Zhou","year":"2017","journal-title":"Eur. J. Pharm. Sci."}],"container-title":["European Journal of Pharmaceutical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928098723002592?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0928098723002592?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T12:09:10Z","timestamp":1760530150000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0928098723002592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":60,"alternative-id":["S0928098723002592"],"URL":"https:\/\/doi.org\/10.1016\/j.ejps.2023.106629","relation":{},"ISSN":["0928-0987"],"issn-type":[{"value":"0928-0987","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel nanomicelle butenafine formulation for ocular drug delivery against fungal keratitis: In Vitro and In Vivo study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Pharmaceutical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejps.2023.106629","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"106629"}}