{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T02:19:53Z","timestamp":1791166793306,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,5,1]],"date-time":"2008-05-01T00:00:00Z","timestamp":1209600000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1016\/j.ejrad.2008.02.011","type":"journal-article","created":{"date-parts":[[2008,3,27]],"date-time":"2008-03-27T14:26:12Z","timestamp":1206627972000},"page":"230-234","source":"Crossref","is-referenced-by-count":247,"title":["Nephrogenic systemic fibrosis associated with gadolinium based contrast agents: A summary of the medical literature reporting"],"prefix":"10.1016","volume":"66","author":[{"given":"Dale R.","family":"Broome","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2008.02.011_bib1","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/S0140-6736(00)02694-5","article-title":"Scleromyxoedema-like cutaneous diseases in renal-dialysis patients","volume":"356","author":"Cowper","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.ejrad.2008.02.011_bib2","doi-asserted-by":"crossref","unstructured":"Grobner T. Gadolinium\u2014a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis? Nephrol Dial Transplant 2006, 21:1104\u2013108 [Erratum in: Nephrol Dial Transplant 2006;21:1745].","DOI":"10.1093\/ndt\/gfk062"},{"key":"10.1016\/j.ejrad.2008.02.011_bib3","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1093\/ndt\/gfg506","article-title":"Nephrogenic fibrosing dermopathy: a novel, disabling disorder in patients with renal failure","volume":"19","author":"Evenepoel","year":"2004","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ejrad.2008.02.011_bib4","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s00467-003-1380-1","article-title":"Nephrogenic fibrosing dermopathy in pediatric patients","volume":"19","author":"Jain","year":"2004","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib5","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/s00467-006-0384-z","article-title":"Gadolinium and nephrogenic fibrosing dermopathy in pediatric patients","volume":"22","author":"Dharnidharka","year":"2007","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib6","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.1681\/ASN.2006060601","article-title":"Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging","volume":"17","author":"Marckmann","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib7","doi-asserted-by":"crossref","first-page":"3344","DOI":"10.1093\/ndt\/gfl379","article-title":"Scleroderma-like syndrome triggered by gadolinium","volume":"21","author":"Nowack","year":"2006","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ejrad.2008.02.011_bib8","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1111\/j.1600-6143.2006.01420.x","article-title":"Nephrogenic systemic fibrosis among liver transplant recipients: a single institution experience and topic update","volume":"6","author":"Maloo","year":"2006","journal-title":"Am J Transplant"},{"key":"10.1016\/j.ejrad.2008.02.011_bib9","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jaad.2006.10.048","article-title":"Gadolinium deposition in nephrogenic fibrosing dermopathy","volume":"56","author":"Boyd","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib10","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jaad.2006.10.047","article-title":"Gadolinium is detectable within the tissue of patients with nephrogenic systemic fibrosis","volume":"56","author":"High","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib11","doi-asserted-by":"crossref","first-page":"586","DOI":"10.2214\/AJR.06.1094","article-title":"Gadodiamide-associated nephrogenic systemic fibrosis\u2014why radiologists should be concerned","volume":"188","author":"Broome","year":"2007","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib12","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1097\/01.rli.0000253505.88945.d5","article-title":"Nephrogenic systemic fibrosis: a review of 6 cases temporally related to gadodiamide injection (Omniscan)","volume":"42","author":"Khurana","year":"2007","journal-title":"Invest Radiol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib13","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1148\/radiol.2431062144","article-title":"Nephrogenic systemic fibrosis: risk factors and incidence estimation","volume":"243","author":"Sadowski","year":"2007","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2008.02.011_bib14","first-page":"137","article-title":"Nephrogenic fibrosing dermopathy associated with exposure to gadolinium-containing contrast agents","volume":"56","author":"Cheng","year":"2007","journal-title":"MMWR"},{"key":"10.1016\/j.ejrad.2008.02.011_bib15","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jaad.2007.02.021","article-title":"Nephrogenic systemic fibrosis: a clinicopathologic study of six cases","volume":"57","author":"Pryor","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib16","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1001\/archderm.143.8.1025","article-title":"Nephrogenic systemic fibrosis: relationship to gadolinium and response to photopheresis","volume":"143","author":"Richmond","year":"2007","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib17","doi-asserted-by":"crossref","first-page":"258","DOI":"10.2215\/CJN.03250906","article-title":"Nephrogenic systemic fibrosis: a mysterious disease in patients with renal failure\u2014role of gadolinium-based contrast media in causation and the beneficial effect of intravenous sodium thiosulfate","volume":"2","author":"Yerram","year":"2007","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib18","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/cmmi.146","article-title":"Long-term retention of gadolinium in tissues from nephrogenic systemic fibrosis patient after multiple gadolinium-enhanced MRI scans: case report and implications","volume":"2","author":"Thakral","year":"2007","journal-title":"Contrast Media Mol Imaging"},{"key":"10.1016\/j.ejrad.2008.02.011_bib19","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1111\/j.1365-2133.2007.08067.x","article-title":"Nephrogenic systemic fibrosis: a case series suggesting gadolinium as a possible aetiological factor","volume":"157","author":"Moreno-Romero","year":"2007","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib20","doi-asserted-by":"crossref","first-page":"3174","DOI":"10.1093\/ndt\/gfm261","article-title":"Case\u2013control study of gadodiamide-related nephrogenic systemic fibrosis","volume":"22","author":"Marckmann","year":"2007","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ejrad.2008.02.011_bib21","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1111\/j.1365-2230.2007.02412.x","article-title":"Possible role of gadolinium in nephrogenic systemic fibrosis: report of two cases and review of the literature","volume":"32","author":"Lim","year":"2007","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib22","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1056\/NEJMc070248","article-title":"Nephrogenic systemic fibrosis, gadolinium, and iron mobilization","volume":"357","author":"Swaminathan","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ejrad.2008.02.011_bib23","doi-asserted-by":"crossref","first-page":"264","DOI":"10.2215\/CJN.03921106","article-title":"Nephrogenic systemic fibrosis: a population study examining the relationship of disease development to gadolinium exposure","volume":"2","author":"Deo","year":"2007","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib24","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1111\/j.1600-6143.2007.01941.x","article-title":"Gadolinium is not the only trigger for nephrogenic systemic fibrosis: insights from two cases and review of the recent literature","volume":"7","author":"Wahba","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1016\/j.ejrad.2008.02.011_bib25","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1148\/radiol.2451070353","article-title":"Gadolinium-enhanced MR imaging and nephrogenic systemic fibrosis: retrospective study of a renal replacement therapy cohort","volume":"245","author":"Collidge","year":"2007","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2008.02.011_bib26","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/j.1365-4632.2007.03301.x","article-title":"Nephrogenic fibrosing dermopathy\/nephrogenic systemic fibrosis: a case series of nine patients and review of the literature","volume":"46","author":"Introcaso","year":"2007","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib27","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.nephro.2007.05.002","article-title":"Nephrogenic systemic fibrosis: more hard times for renal failure patients","volume":"3","author":"Plamondon","year":"2007","journal-title":"Nephrol Ther"},{"key":"10.1016\/j.ejrad.2008.02.011_bib28","doi-asserted-by":"crossref","first-page":"3179","DOI":"10.1093\/ndt\/gfm584","article-title":"Nephrogenic systemic fibrosis after exposure to gadolinium in patients with renal failure","volume":"22","author":"Othersen","year":"2007","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.ejrad.2008.02.011_bib29","doi-asserted-by":"crossref","first-page":"3433","DOI":"10.1002\/art.22925","article-title":"Cutaneous changes of nephrogenic systemic fibrosis: predictor of early mortality and association with gadolinium exposure","volume":"56","author":"Todd","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.ejrad.2008.02.011_bib30","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1445-5994.2007.01252.x","article-title":"Nephrogenic fibrosing dermopathy: a new clinical entity mimicking scleroderma","volume":"37","author":"Cheung","year":"2007","journal-title":"Intern Med J"},{"key":"10.1016\/j.ejrad.2008.02.011_bib31","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1002\/jmri.21136","article-title":"Nephrogenic systemic fibrosis: center case review","volume":"26","author":"Lauenstein","year":"2007","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.ejrad.2008.02.011_bib32","doi-asserted-by":"crossref","first-page":"249","DOI":"10.5414\/CNP68249","article-title":"Nephrogenic systemic fibrosis following exposure to gadolinium-containing contrast agent","author":"Clorius","year":"2007","journal-title":"Clin Nephrol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib33","doi-asserted-by":"crossref","unstructured":"Saussereau E, Lacroix C, Cattaneo A, Mahieu L, Goulle JP. Hair and fingernail gadolinium ICP-MS contents in an overdose case associated with nephrogenic systemic fibrosis. Forensic Sci Int 2007; Nov 3 [Epub ahead of print].","DOI":"10.1016\/j.forsciint.2007.06.026"},{"key":"10.1016\/j.ejrad.2008.02.011_bib34","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1038\/sj.ki.5002460","article-title":"Nephrogenic fibrosing dermopathy in a peritoneal dialysis patient","volume":"72","author":"Tsai","year":"2007","journal-title":"Kidney Int"},{"key":"10.1016\/j.ejrad.2008.02.011_bib35","doi-asserted-by":"crossref","first-page":"395","DOI":"10.2350\/06-05-0093.1","article-title":"Nephrogenic systemic fibrosis with multiorgan involvement in a teenage male after lympoma, Ewing's sarcoma, end-stage renal disease, hemodialysis","volume":"10","author":"Krous","year":"2007","journal-title":"Pediatr Dev Pathol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib36","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/S0151-9638(07)91830-X","article-title":"Nephrogenic fibrosing dermopathy treated with extracorporeal photopheresis: role of gadolinium?","volume":"134","author":"Kintossou","year":"2007","journal-title":"Ann Dermatol Venereol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib37","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/RLI.0b013e31815a3407","article-title":"High prevalence of nephrogenic systemic fibrosis in chronic failure patients exposed to gadodiamide, a gadolinium (Gd) containing magnetic resonance contrast agent","volume":"43","author":"Rydahl","year":"2008","journal-title":"Invest Radiol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib38","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1440-0960.2007.00426.x","article-title":"Nephrogenic systemic fibrosis associated with liver transplantation, renal failure and gadolinium","volume":"49","author":"Caccetta","year":"2008","journal-title":"Aust J Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib39","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1440-0960.2007.00420.x","article-title":"Nephrogenic systemic fibrosis in a gadolinium-naive renal transplant recipient","volume":"49","author":"Anavekar","year":"2008","journal-title":"Aust J Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib40","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jaad.2007.07.018","article-title":"Nephrogenic systemic fibrosis with septal panniculitis mimicking erythema nodosum","volume":"58","author":"Naylor","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib41","doi-asserted-by":"crossref","unstructured":"Kalb RE, Helm TN, Sperry H, Thakral C, Abraham JL, Kanal E. Gadolinium-induced nephrogenic systemic fibrosis in a patient with an acute and transient kidney injury. Br J Dermatol 2007; Dec 11 [Epub ahead of print].","DOI":"10.1111\/j.1365-2133.2007.08369.x"},{"key":"10.1016\/j.ejrad.2008.02.011_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2214\/AJR.07.2822","article-title":"Gadolinium based contrast exposure, nephrogenic systemic fibrosis, gadolinium detection in tissue","volume":"190","author":"Wiginton","year":"2008","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib43","doi-asserted-by":"crossref","unstructured":"Weigle JP, Broome DR. Nephrogenic systemic fibrosis: chronic imaging findings and review of the medical literature. Skeletal Radiol, 2008 Mar.7, [Epub ahead of print].","DOI":"10.1007\/s00256-008-0464-1"},{"key":"10.1016\/j.ejrad.2008.02.011_bib44","unstructured":"Cowper SE. Nephrogenic Fibrosing Dermopathy [NFD\/NSF website]. 2001\u20132007. Available at http:\/\/www.icnfdr.org. Accessed October 20, 2007."},{"key":"10.1016\/j.ejrad.2008.02.011_bib45","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1148\/radiol.2461071267","article-title":"Response to the FDA's May 23 2007, nephrogenic systemic fibrosis update radiology","volume":"246","author":"Kanal","year":"2008","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2008.02.011_bib46","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/s11926-000-0027-5","article-title":"Peripheral blood fibrocytes: mesenchymal precursors cells and the pathogenesis of fibrosis","volume":"2","author":"Chesney","year":"2000","journal-title":"Curr Rheumatol Rep"},{"key":"10.1016\/j.ejrad.2008.02.011_bib47","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.biocel.2003.10.005","article-title":"Circulating fibrocytes: collagen-secreting cells of the peripheral blood","volume":"35","author":"Quan","year":"2004","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib48","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/j.1472-8206.2006.00447.x","article-title":"Clinical and biological consequences of transmetallation induced by contrast agents for magnetic resonance imaging: a review","volume":"20","author":"Idee","year":"2006","journal-title":"Fundam Clin Pharmacol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib49","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1002\/art.20362","article-title":"Dialysis-associated systemic fibrosis (nephrogenic fibrosing dermopathy): study of inflammatory cells and transforming growth factor beta1 expression in affected skin","volume":"50","author":"Jimenez","year":"2004","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.ejrad.2008.02.011_bib50","unstructured":"Edward M, Quinn JA, Mukherjee S, et al. Gadodiamide contrast agent \u2018activates\u2019 fibroblasts: a possible cause of nephrogenic systemic fibrosis. J Pathol 2007; Dec 11 [Epub ahead of print]."},{"key":"10.1016\/j.ejrad.2008.02.011_bib51","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/RLI.0b013e31815e6277","article-title":"A preclinical study to investigate the development of nephrogenic systemic fibrosis: a possible role for gadolinium-based contrast media","volume":"43","author":"Sieber","year":"2008","journal-title":"Invest Radiol"},{"key":"10.1016\/j.ejrad.2008.02.011_bib52","series-title":"Nephrogenic systemic fibrosis and gadolinium-based contrast agents\u2014etiology and risk management","author":"Abu-Alfa","year":"2007"}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X08001149?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X08001149?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T16:04:54Z","timestamp":1557417894000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X08001149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["S0720048X08001149"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2008.02.011","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}