{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T12:47:29Z","timestamp":1783687649672,"version":"3.55.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["ejradiology.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.ejrad.2015.05.005","type":"journal-article","created":{"date-parts":[[2015,5,14]],"date-time":"2015-05-14T01:28:24Z","timestamp":1431566904000},"page":"1436-1443","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":90,"title":["Pancreatic neuroendocrine tumors: Correlation between the contrast-enhanced computed tomography features and the pathological tumor grade"],"prefix":"10.1016","volume":"84","author":[{"given":"Koji","family":"Takumi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Fukukura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiyo","family":"Higashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junnichi","family":"Ideue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomokazu","family":"Umanodan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroto","family":"Hakamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Kanetsuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Yoshiura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2015.05.005_bib0140","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1093\/annonc\/mdn351","article-title":"Pancreatic neuroendocrine tumors (PNETs): incidence, prognosis and recent trend toward improved survival","volume":"19","author":"Halfdanarson","year":"2008","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0145","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1148\/radiology.216.1.r00jl26163","article-title":"Islet cell tumor of the pancreas: biphasic CT versus MR imaging in tumor detection","volume":"216","author":"Ichikawa","year":"2000","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0150","doi-asserted-by":"crossref","first-page":"775","DOI":"10.2214\/ajr.181.3.1810775","article-title":"Preoperative detection of pancreatic insulinomas on multiphasic helical CT","volume":"181","author":"Fidler","year":"2003","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0155","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1148\/rg.262055056","article-title":"Multi-detector row CT of pancreatic islet cell tumors","volume":"26","author":"Horton","year":"2006","journal-title":"Radiographics"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0160","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1148\/rg.306105523","article-title":"Pancreatic endocrine tumors: radiologic-clinicopathologic correlation","volume":"30","author":"Lewis","year":"2010","journal-title":"Radiographics"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0165","doi-asserted-by":"crossref","first-page":"W283","DOI":"10.2214\/AJR.12.8941","article-title":"Pancreatic neuroendocrine tumor with cystlike changes: evaluation with MDCT","volume":"200","author":"Kawamoto","year":"2013","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0170","series-title":"World Health Organization international histological classification of tumours: histological typing of endocrine tumours","author":"Solcia","year":"2000"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0175","series-title":"WHO classification of tumours of the digestive system","first-page":"322","article-title":"Neuroendocrine neoplasms of the pancreas","author":"Klimstra","year":"2010"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0180","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1002\/cncr.23549","article-title":"Prognostic relevance of a novel TNM classification system for upper gastroenteropancreatic neuroendocrine tumors","volume":"113","author":"Pape","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0185","doi-asserted-by":"crossref","first-page":"3332","DOI":"10.1002\/cncr.25855","article-title":"Neuroendocrine tumors of midgut and hindgut origin: tumor-node-metastasis classification determines clinical outcome","volume":"117","author":"Jann","year":"2011","journal-title":"Cancer"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0190","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1159\/000090026","article-title":"Endocrine pancreatic tumours and helical CT: contrast enhancement is correlated with microvascular density, histoprognostic factors and survival","volume":"6","author":"Rodallec","year":"2006","journal-title":"Pancreatology"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0195","doi-asserted-by":"crossref","first-page":"355","DOI":"10.2214\/AJR.11.8037","article-title":"Incidental neuroendocrine tumors of the pancreas: MDCT findings and features of malignancy","volume":"200","author":"Gallotti","year":"2013","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0200","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.ejrad.2007.02.036","article-title":"CT and MR imaging findings of endocrine tumor of the pancreas according to WHO classification","volume":"62","author":"Rha","year":"2007","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0205","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/s00261-012-9953-8","article-title":"Pancreatic neuroendocrine neoplasm: correlation between computed tomography enhancement patterns and prognostic factors of surgical and endoscopic ultrasound-guided fine-needle aspiration biopsy specimens","volume":"38","author":"Tatsumoto","year":"2013","journal-title":"Abdom Imag"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0210","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s00428-006-0250-1","article-title":"TNM staging of foregut (neuro) endocrine tumors: a consensus proposal including a grading system","volume":"449","author":"Rindi","year":"2006","journal-title":"Virchows Arch"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0215","doi-asserted-by":"crossref","first-page":"2945","DOI":"10.1007\/s00330-014-3317-4","article-title":"Pancreatic neuroendocrine tumours: correlation between MSCT features and pathological classification","volume":"24","author":"Luo","year":"2014","journal-title":"Eur Radiol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0220","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1007\/s00330-013-2929-4","article-title":"Non-hyperfunctioning neuroendocrine tumours of the pancreas: MR imaging appearance and correlation with their biological behaviour","volume":"23","author":"Manfredi","year":"2013","journal-title":"Eur Radiol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0225","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.surg.2011.02.022","article-title":"Tumor size correlates with malignancy in nonfunctioning pancreatic endocrine tumor","volume":"150","author":"Bettini","year":"2011","journal-title":"Surgery"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0230","doi-asserted-by":"crossref","first-page":"227","DOI":"10.4132\/KoreanJPathol.2013.47.3.227","article-title":"Proposal for a standardized pathology report of gastroenteropancreatic neuroendocrine tumors: prognostic significance of pathological parameters. Gastrointestinal Pathology Study Group of Korean Society of Pathologists","volume":"47","author":"Cho","year":"2013","journal-title":"Korean J Pathol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0235","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1385\/EP:16:1:033","article-title":"Pathological assessment of pancreatic endocrine tumors for metastatic potential and clinical prognosis","volume":"16","author":"Ohike","year":"2005","journal-title":"Endocr Pathol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0240","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.2214\/ajr.165.5.7572498","article-title":"Islet cell tumors of the pancreas: pathologic-imaging correlation among size, necrosis and cysts, calcification, malignant behavior, and functional status","volume":"165","author":"Buetow","year":"1995","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0245","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1097\/PAS.0b013e31826a0048","article-title":"Cystic pancreatic neuroendocrine tumors: a clinicopathologicstudy","volume":"36","author":"Singhi","year":"2012","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0250","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/S0016-5085(03)01198-3","article-title":"Low microvessel density is an unfavorable histoprognostic factor in pancreatic endocrine tumors","volume":"125","author":"Marion-Audibert","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0255","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/sj.bjc.6602245","article-title":"Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression","volume":"92","author":"Couvelard","year":"2005","journal-title":"Br J Cancer"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0260","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/nrc1093","article-title":"Tumorigenesis and the angiogenic switch","volume":"3","author":"Bergers","year":"2003","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0265","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1148\/radiol.2501080291","article-title":"Pancreatic endocrine tumors: tumor blood flow assessed with perfusion CT reflects angiogenesis and correlates with prognostic factors","volume":"250","author":"d\u2019Assignies","year":"2009","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2015.05.005_bib0270","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1677\/ERC-07-0126","article-title":"Cytological Ki-67 in pancreatic endocrine tumours: an opportunity for pre-operative grading","volume":"15","author":"Piani","year":"2008","journal-title":"Endocr Relat Cancer"}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X15002338?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X15002338?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,22]],"date-time":"2018-09-22T16:56:05Z","timestamp":1537635365000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X15002338"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":27,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["S0720048X15002338"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2015.05.005","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pancreatic neuroendocrine tumors: Correlation between the contrast-enhanced computed tomography features and the pathological tumor grade","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2015.05.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}