{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T22:27:01Z","timestamp":1769207221173,"version":"3.49.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Bundesministerium f\u00fcr Bildung und Forschung (BMBF)","award":["82DZL00401"],"award-info":[{"award-number":["82DZL00401"]}]},{"name":"Bundesministerium f\u00fcr Bildung und Forschung (BMBF)","award":["82DZL004A1"],"award-info":[{"award-number":["82DZL004A1"]}]},{"name":"Christiane Herzog Stiftung, Stuttgart, Germany"},{"name":"Mukoviszidose e.V., Bonn, the German Cystic Fibrosis Association"}],"content-domain":{"domain":["ejradiology.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.ejrad.2018.02.023","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T07:17:26Z","timestamp":1519197446000},"page":"178-183","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Non-contrast enhanced magnetic resonance imaging detects mosaic signal intensity in early cystic fibrosis lung disease"],"prefix":"10.1016","volume":"101","author":[{"given":"Patricia","family":"Leutz-Schmidt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjam","family":"Stahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"Sommerburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Eichinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael U.","family":"Puderbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens-Peter","family":"Schenk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulsattar","family":"Alrajab","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon M.F.","family":"Triphan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Ulrich","family":"Kauczor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus A.","family":"Mall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark O.","family":"Wielp\u00fctz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2018.02.023_bib0005","first-page":"1","article-title":"Pathophysiology of cystic fibrosis lung disease","volume":"64","author":"Mall","year":"2014","journal-title":"Eur. Respir. Monogr."},{"issue":"4","key":"10.1016\/j.ejrad.2018.02.023_bib0010","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1183\/09031936.00228013","article-title":"CFTR: cystic fibrosis and beyond","volume":"44","author":"Mall","year":"2014","journal-title":"Eur. Respir. J."},{"issue":"10059","key":"10.1016\/j.ejrad.2018.02.023_bib0015","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1016\/S0140-6736(16)00576-6","article-title":"Cystic fibrosis","volume":"388","author":"Elborn","year":"2016","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.ejrad.2018.02.023_bib0020","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1097\/00005382-199501040-00007","article-title":"CT mosaic pattern of lung attenuation: etiologies and terminology","volume":"10","author":"Stern","year":"1995","journal-title":"J. Thorac. Imaging"},{"issue":"3","key":"10.1016\/j.ejrad.2018.02.023_bib0025","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1148\/radiol.2462070712","article-title":"Fleischner Society: glossary of terms for thoracic imaging","volume":"246","author":"Hansell","year":"2008","journal-title":"Radiology"},{"issue":"9","key":"10.1016\/j.ejrad.2018.02.023_bib0030","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1055\/s-0042-104936","article-title":"Imaging of cystic fibrosis lung disease and clinical interpretation","volume":"188","author":"Wielp\u00fctz","year":"2016","journal-title":"RoFo: Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin"},{"issue":"6","key":"10.1016\/j.ejrad.2018.02.023_bib0035","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1016\/j.ejrad.2011.02.045","article-title":"Morphologic and functional scoring of cystic fibrosis lung disease using MRI","volume":"81","author":"Eichinger","year":"2012","journal-title":"Eur. J. Radiol."},{"issue":"3","key":"10.1016\/j.ejrad.2018.02.023_bib0040","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1164\/rccm.201604-0893OC","article-title":"Comparison of lung clearance index and magnetic resonance imaging for assessment of lung disease in children with cystic fibrosis","volume":"195","author":"Stahl","year":"2017","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"6","key":"10.1016\/j.ejrad.2018.02.023_bib0045","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/MCP.0000000000000213","article-title":"Imaging modalities in cystic fibrosis: emerging role of MRI","volume":"21","author":"Wielp\u00fctz","year":"2015","journal-title":"Curr. Opin. Pulm. Med."},{"issue":"S44","key":"10.1016\/j.ejrad.2018.02.023_bib0050","doi-asserted-by":"crossref","first-page":"S49","DOI":"10.1002\/ppul.23537","article-title":"Early detection and sensitive monitoring of CF lung disease: prospects of improved and safer imaging","volume":"51","author":"Mall","year":"2016","journal-title":"Pediatr. Pulmonol."},{"issue":"8","key":"10.1016\/j.ejrad.2018.02.023_bib0055","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1164\/rccm.201309-1659OC","article-title":"Magnetic resonance imaging detects changes in structure and perfusion, and response to therapy in early cystic fibrosis lung disease","volume":"189","author":"Wielp\u00fctz","year":"2014","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"7","key":"10.1016\/j.ejrad.2018.02.023_bib0060","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1016\/S1474-4422(17)30158-8","article-title":"Gadolinium deposition in the brain: summary of evidence and recommendations","volume":"16","author":"Gulani","year":"2017","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.ejrad.2018.02.023_bib0065","doi-asserted-by":"crossref","first-page":"95","DOI":"10.4137\/MRI.S12561","article-title":"Contrast-enhanced magnetic resonance imaging in pediatric patients: review and recommendations for current practice","volume":"6","author":"Bhargava","year":"2013","journal-title":"Magn. Resonance Insights"},{"issue":"6","key":"10.1016\/j.ejrad.2018.02.023_bib0070","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1002\/jmri.20198","article-title":"Impact of lung volume on MR signal intensity changes of the lung parenchyma","volume":"20","author":"Bankier","year":"2004","journal-title":"J. Magn. Resonance Imaging"},{"issue":"3","key":"10.1016\/j.ejrad.2018.02.023_bib0075","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1002\/jmri.24840","article-title":"Echo time dependence of observed T1 in the human lung","volume":"42","author":"Triphan","year":"2015","journal-title":"J. Magn. Reson. Imaging"},{"issue":"3","key":"10.1016\/j.ejrad.2018.02.023_bib0080","doi-asserted-by":"crossref","first-page":"e0121520","DOI":"10.1371\/journal.pone.0121520","article-title":"Functional lung MRI in chronic obstructive pulmonary disease: comparison of T1 mapping, oxygen-enhanced T1 mapping and dynamic contrast enhanced perfusion","volume":"10","author":"Jobst","year":"2015","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.ejrad.2018.02.023_bib0085","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1164\/rccm.201107-1348OC","article-title":"Alveolarization continues during childhood and adolescence: new evidence from helium-3 magnetic resonance","volume":"185","author":"Narayanan","year":"2012","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"3","key":"10.1016\/j.ejrad.2018.02.023_bib0090","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1002\/mrm.22031","article-title":"Non-contrast-enhanced perfusion and ventilation assessment of the human lung by means of fourier decomposition in proton MRI","volume":"62","author":"Bauman","year":"2009","journal-title":"Magn. Reson. Med."},{"issue":"7","key":"10.1016\/j.ejrad.2018.02.023_bib0095","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/ppul.23190","article-title":"Five years of experience with biochemical cystic fibrosis newborn screening based on IRT\/PAP in Germany","volume":"50","author":"Sommerburg","year":"2015","journal-title":"Pediatr. Pulmonol."},{"issue":"2","key":"10.1016\/j.ejrad.2018.02.023_bib0100","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1177\/096228029900800204","article-title":"Measuring agreement in method comparison studies","volume":"8","author":"Bland","year":"1999","journal-title":"Stat. Methods Med. Res."},{"issue":"4","key":"10.1016\/j.ejrad.2018.02.023_bib0105","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1037\/h0026256","article-title":"Weighted kappa: nominal scale agreement with provision for scaled disagreement or partial credit","volume":"70","author":"Cohen","year":"1968","journal-title":"Psychol. Bull."},{"issue":"1","key":"10.1016\/j.ejrad.2018.02.023_bib0110","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics"},{"issue":"4","key":"10.1016\/j.ejrad.2018.02.023_bib0115","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1097\/RTI.0b013e3182277113","article-title":"Computed tomographic imaging of the airways in COPD and asthma","volume":"26","author":"Kauczor","year":"2011","journal-title":"J. Thorac. Imaging"},{"issue":"10","key":"10.1016\/j.ejrad.2018.02.023_bib0120","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1097\/RLI.0b013e318074fd81","article-title":"Assessment of morphological MRI for pulmonary changes in cystic fibrosis (CF) patients: comparison to thin-section CT and chest x-ray","volume":"42","author":"Puderbach","year":"2007","journal-title":"Invest. Radiol."},{"issue":"3","key":"10.1016\/j.ejrad.2018.02.023_bib0125","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.ejrad.2007.08.009","article-title":"MR imaging of the chest: a practical approach at 1.5\u202fT","volume":"64","author":"Puderbach","year":"2007","journal-title":"Eur. J. Radiol."},{"issue":"10","key":"10.1016\/j.ejrad.2018.02.023_bib0130","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1097\/RLI.0000000000000178","article-title":"Comparison between magnetic resonance imaging and computed tomography of the lung in patients with cystic fibrosis with regard to clinical, laboratory, and pulmonary functional parameters","volume":"50","author":"Renz","year":"2015","journal-title":"Invest. Radiol."},{"issue":"1","key":"10.1016\/j.ejrad.2018.02.023_bib0135","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1148\/radiol.15141655","article-title":"Quiet submillimeter MR imaging of the lung is feasible with a PETRA sequence at 1.5T","volume":"276","author":"Dournes","year":"2015","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.ejrad.2018.02.023_bib0140","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1002\/ppul.23328","article-title":"Validating chest MRI to detect and monitor cystic fibrosis lung disease in a pediatric cohort","volume":"51","author":"Tepper","year":"2016","journal-title":"Pediatr. Pulmonol."},{"issue":"6","key":"10.1016\/j.ejrad.2018.02.023_bib0145","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.ejrad.2015.02.011","article-title":"Reversibility of trapped air on chest computed tomography in cystic fibrosis patients","volume":"84","author":"Loeve","year":"2015","journal-title":"Eur. J. Radiol."},{"issue":"3","key":"10.1016\/j.ejrad.2018.02.023_bib0150","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1007\/s00330-015-3850-9","article-title":"Assessment of CF lung disease using motion corrected PROPELLER MRI: a comparison with CT","volume":"26","author":"Ciet","year":"2016","journal-title":"Eur. Radiol."}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X18300597?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X18300597?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,14]],"date-time":"2022-08-14T16:31:46Z","timestamp":1660494706000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X18300597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":30,"alternative-id":["S0720048X18300597"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2018.02.023","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Non-contrast enhanced magnetic resonance imaging detects mosaic signal intensity in early cystic fibrosis lung disease","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2018.02.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}