{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:57:16Z","timestamp":1790506636381,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Bundesministerium f\u00fcr Bildung und Forschung (BMBF)","award":["82DZL004A"],"award-info":[{"award-number":["82DZL004A"]}]},{"name":"Bundesministerium f\u00fcr Bildung und Forschung (BMBF)","award":["82DZL004A2"],"award-info":[{"award-number":["82DZL004A2"]}]},{"name":"Bundesministerium f\u00fcr Bildung und Forschung (BMBF)","award":["82DZL004A4"],"award-info":[{"award-number":["82DZL004A4"]}]}],"content-domain":{"domain":["ejradiology.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.ejrad.2018.08.007","type":"journal-article","created":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T12:58:49Z","timestamp":1533819529000},"page":"33-38","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Quantitative CT detects changes in airway dimensions and air-trapping after bronchial thermoplasty for severe asthma"],"prefix":"10.1016","volume":"107","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8580-6721","authenticated-orcid":false,"given":"Philip","family":"Konietzke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Weinheimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark O.","family":"Wielp\u00fctz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willi L.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philine","family":"Kaukel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Eberhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus P.","family":"Heussel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Ulrich","family":"Kauczor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix J.","family":"Herth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Schuhmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.ejrad.2018.08.007_bib0005","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1183\/09031936.00202013","article-title":"International ERS\/ATS guidelines on definition, evaluation and treatment of severe asthma","volume":"43","author":"Chung","year":"2014","journal-title":"Eur. Respir. J."},{"issue":"2","key":"10.1016\/j.ejrad.2018.08.007_bib0010","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1164\/rccm.200903-0354OC","article-title":"Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial","volume":"181","author":"Castro","year":"2010","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"12","key":"10.1016\/j.ejrad.2018.08.007_bib0015","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1164\/rccm.200704-571OC","article-title":"Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma","volume":"176","author":"Pavord","year":"2007","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"6","key":"10.1016\/j.ejrad.2018.08.007_bib0020","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.jaci.2013.08.009","article-title":"Bronchial thermoplasty: long-term safety and effectiveness in patients with severe persistent asthma","volume":"132","author":"Wechsler","year":"2013","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.ejrad.2018.08.007_bib0025","article-title":"The efficacy and safety of Bronchial Thermoplasty in Severe Persistent Asthma on extended follow-up","author":"O\u2019Reilly","year":"2017","journal-title":"QJM"},{"issue":"134","key":"10.1016\/j.ejrad.2018.08.007_bib0030","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1183\/09059180.00005114","article-title":"Bronchial thermoplasty: a new therapeutic option for the treatment of severe, uncontrolled asthma in adults","volume":"23","author":"Dombret","year":"2014","journal-title":"Eur. Respir. Rev."},{"issue":"11","key":"10.1016\/j.ejrad.2018.08.007_bib0035","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/s11882-014-0470-4","article-title":"Critical review of bronchial thermoplasty: where should it fit into asthma therapy?","volume":"14","author":"Sheshadri","year":"2014","journal-title":"Curr. Allergy Asthma Rep."},{"issue":"1","key":"10.1016\/j.ejrad.2018.08.007_bib0040","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s12890-017-0554-8","article-title":"Nerve ablation after bronchial thermoplasty and sustained improvement in severe asthma","volume":"18","author":"Facciolongo","year":"2018","journal-title":"BMC Pulm. Med."},{"issue":"2","key":"10.1016\/j.ejrad.2018.08.007_bib0045","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1165\/rcmb.2009-0259OC","article-title":"Acute response of airway muscle to extreme temperature includes disruption of actin-myosin interaction","volume":"44","author":"Dyrda","year":"2011","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"12","key":"10.1016\/j.ejrad.2018.08.007_bib0050","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1164\/rccm.201407-1374LE","article-title":"Reduction of airway smooth muscle mass by bronchial thermoplasty in patients with severe asthma","volume":"190","author":"Pretolani","year":"2014","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"11","key":"10.1016\/j.ejrad.2018.08.007_bib0055","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1016\/j.acra.2005.08.013","article-title":"Quantitative computed tomography of chronic obstructive pulmonary disease","volume":"12","author":"Coxson","year":"2005","journal-title":"Acad. Radiol."},{"issue":"3","key":"10.1016\/j.ejrad.2018.08.007_bib0060","doi-asserted-by":"crossref","first-page":"W460","DOI":"10.2214\/AJR.12.10102","article-title":"Relationships between airflow obstruction and quantitative CT measurements of emphysema, air trapping, and airways in subjects with and without chronic obstructive pulmonary disease","volume":"201","author":"Schroeder","year":"2013","journal-title":"Am. J. Roentgenol."},{"issue":"2","key":"10.1016\/j.ejrad.2018.08.007_bib0065","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1097\/RTI.0b013e3182765785","article-title":"Automatic airway analysis on multidetector computed tomography in cystic fibrosis: correlation with pulmonary function testing","volume":"28","author":"Wielputz","year":"2013","journal-title":"J. Thorac. Imaging"},{"issue":"8","key":"10.1016\/j.ejrad.2018.08.007_bib0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073142","article-title":"Pulmonary emphysema in cystic fibrosis detected by densitometry on chest multidetector computed tomography","volume":"8","author":"Wielputz","year":"2013","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.ejrad.2018.08.007_bib0075","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.4187\/respcare.02175","article-title":"Airway dimensions in asthma and COPD in high resolution computed tomography: can we see the difference?","volume":"58","author":"Kosciuch","year":"2013","journal-title":"Respir. Care"},{"issue":"3","key":"10.1016\/j.ejrad.2018.08.007_bib0080","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1136\/thorax.57.3.247","article-title":"High resolution computed tomographic assessment of airway wall thickness in chronic asthma: reproducibility and relationship with lung function and severity","volume":"57","author":"Little","year":"2002","journal-title":"Thorax"},{"issue":"5","key":"10.1016\/j.ejrad.2018.08.007_bib0085","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.jaci.2006.07.032","article-title":"Role of small airways in asthma: investigation using high-resolution computed tomography","volume":"118","author":"Ueda","year":"2006","journal-title":"J. Allergy Clin. Immunol."},{"issue":"6","key":"10.1016\/j.ejrad.2018.08.007_bib0090","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1378\/chest.09-0174","article-title":"Qualitative analysis of high-resolution CT scans in severe asthma","volume":"136","author":"Gupta","year":"2009","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.ejrad.2018.08.007_bib0095","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.ejrad.2009.03.023","article-title":"Contrast enhanced CT-scans are not comparable to non-enhanced scans in emphysema quantification","volume":"74","author":"Heussel","year":"2010","journal-title":"Eur. J. Radiol."},{"issue":"4","key":"10.1016\/j.ejrad.2018.08.007_bib0100","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1097\/RTI.0b013e3182277113","article-title":"Computed tomographic imaging of the airways in COPD and asthma","volume":"26","author":"Kauczor","year":"2011","journal-title":"J. Thorac. Imaging"},{"issue":"1","key":"10.1016\/j.ejrad.2018.08.007_bib0105","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1109\/TMI.2007.902798","article-title":"About objective 3-d analysis of airway geometry in computerized tomography","volume":"27","author":"Weinheimer","year":"2008","journal-title":"IEEE Trans. Med. Imaging"},{"issue":"10","key":"10.1016\/j.ejrad.2018.08.007_bib0110","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1007\/s00330-009-1437-z","article-title":"Fully automatic quantitative assessment of emphysema in computed tomography: comparison with pulmonary function testing and normal values","volume":"19","author":"Heussel","year":"2009","journal-title":"Eur. Radiol."},{"issue":"8","key":"10.1016\/j.ejrad.2018.08.007_bib0115","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0182268","article-title":"Influence of exposure parameters and iterative reconstruction on automatic airway segmentation and analysis on MDCT-An ex vivo phantom study","volume":"12","author":"Leutz-Schmidt","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.ejrad.2018.08.007_bib0120","series-title":"Proc. of Second International Workshop on Pulmonary Image Analysis (in Conjunction with MICCAI) 2009","article-title":"Fully automated extraction of airways from CT scans based on self-adapting region growing","author":"Weinheimer","year":"2009"},{"key":"10.1016\/j.ejrad.2018.08.007_bib0125","series-title":"Fourth International Workshop on Pulmonary Image Analysis 2011","first-page":"241","article-title":"Automatic lung segmentation in MDCT images","author":"Weinheimer","year":"2011"},{"key":"10.1016\/j.ejrad.2018.08.007_bib0130","series-title":"International Society for Optics and Photonics, 2017","article-title":"Fully automated lobe-based airway taper index calculation in a low dose MDCT CF study over 4 time-points","author":"Weinheimer","year":"2017"},{"issue":"4","key":"10.1016\/j.ejrad.2018.08.007_bib0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0194557","article-title":"Validation of automated lobe segmentation on paired inspiratory-expiratory chest CT in 8-14 year-old children with cystic fibrosis","volume":"13","author":"Konietzke","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.ejrad.2018.08.007_bib0140","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1465-9921-14-11","article-title":"Low-dose CT measurements of airway dimensions and emphysema associated with airflow limitation in heavy smokers: a cross sectional study","volume":"14","author":"Dijkstra","year":"2013","journal-title":"Respir. Res."},{"issue":"3","key":"10.1016\/j.ejrad.2018.08.007_bib0145","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/j.1440-1843.2011.02117.x","article-title":"Quantitative pulmonary imaging using computed tomography and magnetic resonance imaging","volume":"17","author":"Washko","year":"2012","journal-title":"Respirology"},{"issue":"3 Pt 1","key":"10.1016\/j.ejrad.2018.08.007_bib0150","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1164\/ajrccm.162.3.9907120","article-title":"Computed tomographic measurements of airway dimensions and emphysema in smokers. Correlation with lung function","volume":"162","author":"Nakano","year":"2000","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"4","key":"10.1016\/j.ejrad.2018.08.007_bib0155","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1183\/09031936.00167908","article-title":"Quantitative computed tomography: emphysema and airway wall thickness by sex, age and smoking","volume":"34","author":"Grydeland","year":"2009","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.ejrad.2018.08.007_bib0160","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1465-9921-14-42","article-title":"Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD","volume":"14","author":"Hersh","year":"2013","journal-title":"Respir. Res."},{"issue":"5","key":"10.1016\/j.ejrad.2018.08.007_bib0165","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1378\/chest.123.5.1655","article-title":"An automated approach to quantitative air trapping measurements in mild cystic fibrosis","volume":"123","author":"Goris","year":"2003","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.ejrad.2018.08.007_bib0170","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1183\/09031936.00080312","article-title":"Multi-ethnic reference values for spirometry for the 3\u201395 year age range: the global lung function 2012 equations: report of the global lung function initiative (GLI), ERS task force to establish improved lung function reference values","volume":"40","author":"Quanjer","year":"2012","journal-title":"Eur. Respir. J."},{"issue":"3","key":"10.1016\/j.ejrad.2018.08.007_bib0175","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.alit.2016.12.008","article-title":"Use of 3D-CT airway analysis software to assess a patient with severe persistent bronchial asthma treated with bronchial thermoplasty","volume":"66","author":"Ishii","year":"2017","journal-title":"Allergol. Int."},{"key":"10.1016\/j.ejrad.2018.08.007_bib0180","first-page":"1","article-title":"Use of MDCT to assess the results of bronchial thermoplasty","author":"Zanon","year":"2017","journal-title":"Am. J. Roentgenol."},{"issue":"3","key":"10.1016\/j.ejrad.2018.08.007_bib0185","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01565-2016","article-title":"Early computed tomography modifications following bronchial thermoplasty in patients with severe asthma","volume":"49","author":"Debray","year":"2017","journal-title":"Eur. Respir. J."},{"issue":"4","key":"10.1016\/j.ejrad.2018.08.007_bib0190","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1136\/thx.2008.103671","article-title":"Relationship between improved airflow limitation and changes in airway calibre induced by inhaled anticholinergic agents in COPD","volume":"64","author":"Hasegawa","year":"2009","journal-title":"Thorax"},{"issue":"5","key":"10.1016\/j.ejrad.2018.08.007_bib0195","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1136\/thoraxjnl-2014-206146","article-title":"Targeted lung denervation for moderate to severe COPD: a pilot study","volume":"70","author":"Slebos","year":"2015","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.ejrad.2018.08.007_bib0200","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1378\/chest.08-0049","article-title":"A multivariate analysis of risk factors for the air-trapping asthmatic phenotype as measured by quantitative CT analysis","volume":"135","author":"Busacker","year":"2009","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.ejrad.2018.08.007_bib0205","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3904\/kjim.2002.17.1.24","article-title":"Evaluation of emphysema in patients with asthma using high-resolution CT","volume":"17","author":"Hong","year":"2002","journal-title":"Korean J. Intern. Med."},{"issue":"2","key":"10.1016\/j.ejrad.2018.08.007_bib0210","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00017-2017","article-title":"Long-term outcomes of bronchial thermoplasty in subjects with severe asthma: a comparison of 3-year follow-up results from two prospective multicentre studies","volume":"50","author":"Chupp","year":"2017","journal-title":"Eur. Respir. J."}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X18302754?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X18302754?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T11:26:07Z","timestamp":1538565967000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X18302754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":42,"alternative-id":["S0720048X18302754"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2018.08.007","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quantitative CT detects changes in airway dimensions and air-trapping after bronchial thermoplasty for severe asthma","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2018.08.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}