{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T20:35:04Z","timestamp":1767904504323,"version":"3.49.0"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejradiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.ejrad.2019.108739","type":"journal-article","created":{"date-parts":[[2019,11,7]],"date-time":"2019-11-07T11:40:44Z","timestamp":1573126844000},"page":"108739","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"special_numbering":"C","title":["Differentiating diffuse from focal pattern on Computed Tomography in multiple myeloma: Added value of a Radiomics approach"],"prefix":"10.1016","volume":"121","author":[{"given":"Alberto Stefano","family":"Tagliafico","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Cea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federica","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Valdora","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bianca","family":"Bignotti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giulia","family":"Succio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Gualco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessio","family":"Conte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alida","family":"Dominietto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2019.108739_bib0005","series-title":"Harrison\u2019s Principles of Internal Medicine","author":"Larry Jameson","year":"2018"},{"key":"10.1016\/j.ejrad.2019.108739_bib0010","series-title":"Bones in Multiple Myeloma: Imaging and Therapy","first-page":"638","author":"Zamagni","year":"2018"},{"key":"10.1016\/j.ejrad.2019.108739_bib0015","doi-asserted-by":"crossref","first-page":"152","DOI":"10.2214\/AJR.16.17219","article-title":"A comparison of different staging systems for multiple myeloma: can the MRI pattern play a prognostic role?","volume":"209","author":"Filonzi","year":"2017","journal-title":"AJR Am. J. Roentgenol."},{"key":"10.1016\/j.ejrad.2019.108739_bib0020","doi-asserted-by":"crossref","DOI":"10.1038\/bcj.2015.87","article-title":"Positron emission tomography-computed tomography in the diagnostic evaluation of smoldering multiple myeloma: identification of patients needing therapy","volume":"5","author":"Siontis","year":"2015","journal-title":"Blood Cancer J."},{"key":"10.1016\/j.ejrad.2019.108739_bib0025","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1200\/JCO.2009.25.5356","article-title":"Prognostic significance of focal lesions in whole-body magnetic resonance imaging in patients with asymptomatic multiple myeloma","volume":"28","author":"Hillengass","year":"2010","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.ejrad.2019.108739_bib0030","doi-asserted-by":"crossref","first-page":"e538","DOI":"10.1016\/S1470-2045(14)70442-5","article-title":"International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma","volume":"15","author":"Rajkumar","year":"2014","journal-title":"Lancet Oncol."},{"key":"10.1016\/j.ejrad.2019.108739_bib0035","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1007\/s00259-017-3909-8","article-title":"Interpretation criteria for FDG PET\/CT in multiple myeloma (IMPeTUs): final results. IMPeTUs (Italian myeloma criteria for PET USe)","volume":"45","author":"Nanni","year":"2018","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.ejrad.2019.108739_bib0040","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1148\/radiol.2015151169","article-title":"Radiomics: images are more than pictures, they are data","volume":"278","author":"Gillies","year":"2016","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2019.108739_bib0045","doi-asserted-by":"crossref","DOI":"10.1007\/s10549-018-4675-4","article-title":"Rapid review: radiomics and breast cancer","volume":"169","author":"Valdora","year":"2018","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.ejrad.2019.108739_bib0050","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.breast.2018.04.016","article-title":"An exploratory radiomics analysis on digital breast tomosynthesis in women with mammographically negative dense breasts","volume":"40","author":"Tagliafico","year":"2018","journal-title":"Breast (Edinburgh, Scotland)"},{"key":"10.1016\/j.ejrad.2019.108739_bib0055","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-012799","article-title":"STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration","volume":"6","author":"Cohen","year":"2016","journal-title":"BMJ Open"},{"key":"10.1016\/j.ejrad.2019.108739_bib0060","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1148\/radiol.2016160363","article-title":"Quantitative diffusion-weighted imaging of the bone marrow: an adjunct tool for the diagnosis of a diffuse MR imaging pattern in patients with multiple myeloma","volume":"282","author":"Koutoulidis","year":"2017","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2019.108739_bib0065","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.2214\/ajr.167.4.8819407","article-title":"Contrast enhancement and quantitative signal analysis in MR imaging of multiple myeloma: assessment of focal and diffuse growth patterns in marrow correlated with biopsies and survival rates","volume":"167","author":"St\u00e4bler","year":"1996","journal-title":"AJR Am. J. Roentgenol."},{"key":"10.1016\/j.ejrad.2019.108739_bib0070","doi-asserted-by":"crossref","first-page":"728","DOI":"10.2214\/AJR.09.3130","article-title":"Relationship between fatty degeneration of thigh muscles and vitamin d status in the elderly: a preliminary MRI study","volume":"194","author":"Tagliafico","year":"2010","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/j.ejrad.2019.108739_bib0075","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/j.mri.2012.05.001","article-title":"3D Slicer as an image computing platform for the Quantitative Imaging Network","volume":"30","author":"Fedorov","year":"2012","journal-title":"Magn. Reson. Imaging"},{"key":"10.1016\/j.ejrad.2019.108739_bib0080","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/23808993.2016.1164013","article-title":"Radiomics: a new application from established techniques","volume":"1","author":"Parekh","year":"2016","journal-title":"Expert Rev. Precis. Med. Drug Dev."},{"key":"10.1016\/j.ejrad.2019.108739_bib0085","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s10549-018-4675-4","article-title":"Rapid review: radiomics and breast cancer","volume":"169","author":"Valdora","year":"2018","journal-title":"Breast Cancer Res. Treat."},{"key":"10.1016\/j.ejrad.2019.108739_bib0090","doi-asserted-by":"crossref","first-page":"5083","DOI":"10.1007\/s00330-018-5537-5","article-title":"Dual-energy CT of the bone marrow in multiple myeloma: diagnostic accuracy for quantitative differentiation of infiltration patterns","volume":"28","author":"Kosmala","year":"2018","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.ejrad.2019.108739_bib0095","article-title":"Nerve density: a new parameter to evaluate peripheral nerve pathology on ultrasound","volume":"36","author":"Tagliafico","year":"2010","journal-title":"Prelim. Study, Ultras. Med. Biol."}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X19303894?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X19303894?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T07:16:08Z","timestamp":1759994168000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X19303894"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":19,"alternative-id":["S0720048X19303894"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2019.108739","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differentiating diffuse from focal pattern on Computed Tomography in multiple myeloma: Added value of a Radiomics approach","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2019.108739","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"108739"}}