{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T21:08:14Z","timestamp":1762376894015,"version":"build-2065373602"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejradiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.ejrad.2021.109632","type":"journal-article","created":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T04:35:14Z","timestamp":1615091714000},"page":"109632","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Quantitative CT assessment by histogram and volume ratio in pyrrolizidines alkaloids-induced hepatic sinusoidal obstruction syndrome"],"prefix":"10.1016","volume":"138","author":[{"given":"Xiaoqian","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Lei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhu","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenyu","family":"Fei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Ai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haitao","family":"Shang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Bai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1521-1746","authenticated-orcid":false,"given":"Jin","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2021.109632_bib0005","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1055\/s-2002-23204","article-title":"Toxic injury to hepatic sinusoids: sinusoidal obstruction syndrome (veno-occlusive disease)","volume":"22","author":"DeLeve","year":"2002","journal-title":"Semin. Liver Dis."},{"key":"10.1016\/j.ejrad.2021.109632_bib0010","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1002\/hep.22772","article-title":"Vascular disorders of the liver","volume":"49","author":"DeLeve","year":"2009","journal-title":"Hepatology"},{"issue":"Suppl 1","key":"10.1016\/j.ejrad.2021.109632_bib0015","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/S0168-8278(12)60004-X","article-title":"Management of hepatic vascular diseases","volume":"56","author":"Plessier","year":"2012","journal-title":"J. Hepatol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0020","doi-asserted-by":"crossref","DOI":"10.1111\/bjh.15017","article-title":"Abdominal computed tomography angiography in post-transplantation sinusoidal obstruction syndrome associated with R-DHAOX\/BEAM toxicity","volume":"180","author":"Lavol\u00e9","year":"2018","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0025","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.clinre.2016.01.006","article-title":"Sinusoidal obstruction syndrome","volume":"40","author":"Valla","year":"2016","journal-title":"Clin. Res. Hepatol. Gastroenterol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0030","doi-asserted-by":"crossref","first-page":"3753","DOI":"10.3748\/wjg.v25.i28.3753","article-title":"Pyrrolizidine alkaloids-induced hepatic sinusoidal obstruction syndrome: pathogenesis, clinical manifestations, diagnosis, treatment, and outcomes","volume":"25","author":"Yang","year":"2019","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0035","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.jhep.2010.07.031","article-title":"Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum","volume":"54","author":"Lin","year":"2011","journal-title":"J. Hepatol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0040","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/jgh.14612","article-title":"Expert consensus on the clinical management of pyrrolizidine alkaloid induced hepatic sinusoidal obstruction syndrome","volume":"34","author":"Zhuge","year":"2019","journal-title":"J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0045","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1038\/bmt.2015.52","article-title":"Sinusoidal obstruction syndrome\/veno-occlusive disease: current situation and perspectives\u2014a position statement from the European Society for Blood and Marrow Transplantation (EBMT)","volume":"50","author":"Mohty","year":"2015","journal-title":"Bone Marrow Transpl."},{"key":"10.1016\/j.ejrad.2021.109632_bib0050","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1111\/liv.13684","article-title":"Clinical characteristics and treatment of pyrrolizidine alkaloid-related hepatic vein occlusive disease","volume":"38","author":"Zhuge","year":"2018","journal-title":"Liver Int."},{"key":"10.1016\/j.ejrad.2021.109632_bib0055","doi-asserted-by":"crossref","first-page":"e942","DOI":"10.1097\/MD.0000000000000942","article-title":"Tusanqi-related sinusoidal obstruction syndrome in China","volume":"94","author":"Wang","year":"2015","journal-title":"Medicine"},{"key":"10.1016\/j.ejrad.2021.109632_bib0060","doi-asserted-by":"crossref","DOI":"10.1186\/s12876-018-0879-7","article-title":"Risk factors for hepatic veno-occlusive disease caused by Gynura segetum: a retrospective study","volume":"18","author":"Wang","year":"2018","journal-title":"BMC Gastroenterol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0065","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1038\/s41598-018-37775-1","article-title":"Gadoxetic acid-enhanced hepatobiliary-phase magnetic resonance imaging for pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome and association with liver function","volume":"9","author":"Guo","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ejrad.2021.109632_bib0070","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1111\/j.1751-2980.2011.00552.x","article-title":"Definitive diagnosis of hepatic sinusoidal obstruction syndrome induced by pyrrolizidine alkaloids","volume":"13","author":"Gao","year":"2012","journal-title":"J. Dig. Dis."},{"key":"10.1016\/j.ejrad.2021.109632_bib0075","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1872-034X.2011.00918.x","article-title":"Hepatic veno-occlusive disease after taking Gynura rhizome: the value of multidetector computed tomography in diagnosing the disease and evaluating the clinical therapeutic effect","volume":"42","author":"Wu","year":"2012","journal-title":"Hepatol. Res."},{"key":"10.1016\/j.ejrad.2021.109632_bib0080","doi-asserted-by":"crossref","first-page":"218","DOI":"10.3348\/kjr.2014.15.2.218","article-title":"Hepatic sinusoidal obstruction syndrome caused by herbal medicine: CT and MRI features","volume":"15","author":"Zhou","year":"2014","journal-title":"Korean J. Radiol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0085","doi-asserted-by":"crossref","DOI":"10.1038\/srep37998","article-title":"Diagnostic performance of contrast-enhanced CT in pyrrolizidine alkaloids-induced hepatic sinusoidal obstructive syndrome","volume":"6","author":"Kan","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ejrad.2021.109632_bib0090","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.cgh.2017.01.009","article-title":"Magnetic resonance imaging findings in patients with pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome","volume":"15","author":"Li","year":"2017","journal-title":"Clin. Gastroenterol. Hepatol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0095","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.3390\/cancers12061486","article-title":"Liver tumor burden in pancreatic neuroendocrine tumors: CT features and texture analysis in the prediction of tumor grade and (18)F-FDG uptake","volume":"12","author":"Beleu","year":"2020","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.ejrad.2021.109632_bib0100","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1007\/s00330-020-07235-4","article-title":"Whole-liver histogram and texture analysis on T1 maps improves the risk stratification of advanced fibrosis in NAFLD","volume":"31","author":"Xu","year":"2021","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0105","doi-asserted-by":"crossref","first-page":"5284","DOI":"10.1007\/s00330-018-5454-7","article-title":"CT attenuation of liver metastases before targeted therapy is a prognostic factor of overall survival in colorectal cancer patients. Results from the randomised, open-label FIRE-3\/AIO KRK0306 trial","volume":"28","author":"Froelich","year":"2018","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0110","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1007\/s00259-017-3779-0","article-title":"Elevated tumor-to-liver uptake ratio (TLR) from (18)F-FDG-PET\/CT predicts poor prognosis in stage IIA colorectal cancer following curative resection","volume":"44","author":"Huang","year":"2017","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"key":"10.1016\/j.ejrad.2021.109632_bib0115","article-title":"Computational quantitative measures of Gd-EOB-DTPA enhanced MRI hepatobiliary phase images can predict microvascular invasion of small HCC","volume":"13","author":"Wang","year":"2020","journal-title":"Eur. J. Radiol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0120","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.diii.2019.05.006","article-title":"Intra arterial treatment of hepatocellular carcinoma: comparison of MELD score variations between radio-embolization and chemo-embolization","volume":"100","author":"Delicque","year":"2019","journal-title":"Diagn. Interv. Imaging"},{"key":"10.1016\/j.ejrad.2021.109632_bib0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/5193028","article-title":"Assessing the prognostic performance of the child-pugh, model for end-stage liver disease, and albumin-bilirubin scores in patients with decompensated cirrhosis: a large Asian cohort from gastroenterology department","volume":"2020","author":"Wan","year":"2020","journal-title":"Dis. Markers"},{"key":"10.1016\/j.ejrad.2021.109632_bib0130","article-title":"Quantitative analysis of CT images in patients with pyrrolizidine alkaloid-induced sinusoidal obstruction syndrome","volume":"9","author":"Wang","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ejrad.2021.109632_bib0135","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1148\/radiol.2015141749","article-title":"Hepatic parenchymal heterogeneity on contrast-enhanced CT scans following oxaliplatin-based chemotherapy: natural history and association with clinical evidence of sinusoidal obstruction syndrome","volume":"276","author":"Han","year":"2015","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2021.109632_bib0140","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1148\/radiol.13131810","article-title":"Chemotherapy-induced focal hepatopathy in patients with gastrointestinal malignancy: gadoxetic acid--enhanced and diffusion-weighted MR imaging with clinical-pathologic correlation","volume":"271","author":"Han","year":"2014","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2021.109632_bib0145","article-title":"Liver enhancement during hepatobiliary phase after Gd-BOPTA administration: correlation with liver and renal function","author":"Bonatti","year":"2020","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.ejrad.2021.109632_bib0150","doi-asserted-by":"crossref","DOI":"10.1186\/s12876-020-1180-0","article-title":"Clinical characteristics, CT signs, and pathological findings of Pyrrolizidine alkaloids-induced sinusoidal obstructive syndrome: a retrospective study","volume":"20","author":"Liu","year":"2020","journal-title":"BMC Gastroenterol."}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X21001121?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X21001121?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T07:21:31Z","timestamp":1759994491000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X21001121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":30,"alternative-id":["S0720048X21001121"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2021.109632","relation":{},"ISSN":["0720-048X"],"issn-type":[{"type":"print","value":"0720-048X"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quantitative CT assessment by histogram and volume ratio in pyrrolizidines alkaloids-induced hepatic sinusoidal obstruction syndrome","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2021.109632","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109632"}}