{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:29:35Z","timestamp":1760956175115,"version":"build-2065373602"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejradiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.ejrad.2022.110568","type":"journal-article","created":{"date-parts":[[2022,10,18]],"date-time":"2022-10-18T12:50:08Z","timestamp":1666097408000},"page":"110568","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Elevated GABA level in the precuneus and its association with pain intensity in patients with postherpetic neuralgia: An initial proton magnetic resonance spectroscopy study"],"prefix":"10.1016","volume":"157","author":[{"given":"Xiaojuan","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junpeng","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuting","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonggang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"18","key":"10.1016\/j.ejrad.2022.110568_b0005","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1016\/S0264-410X(98)00137-6","article-title":"Postherpetic neuralgia in immunocompetent elderly people","volume":"16","author":"Schmader","year":"1998","journal-title":"Vaccine"},{"issue":"8","key":"10.1016\/j.ejrad.2022.110568_b0010","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/S1474-4422(10)70143-5","article-title":"Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment","volume":"9","author":"Baron","year":"2010","journal-title":"Lancet Neurol."},{"issue":"2","key":"10.1016\/j.ejrad.2022.110568_b0015","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1093\/brain\/119.2.347","article-title":"The relationship of pain, allodynia and thermal sensation in post-herpetic neuralgia","volume":"119","author":"Rowbotham","year":"1996","journal-title":"Brain: J. Neurol."},{"key":"10.1016\/j.ejrad.2022.110568_b0020","doi-asserted-by":"crossref","DOI":"10.1186\/1741-7015-8-37","article-title":"The impact of herpes zoster and post-herpetic neuralgia on quality-of-life","volume":"8","author":"Johnson","year":"2010","journal-title":"BMC Med."},{"issue":"7","key":"10.1016\/j.ejrad.2022.110568_b0025","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1111\/ijcp.12411","article-title":"Systematic review and meta-analysis of pharmacological therapies for pain associated with postherpetic neuralgia and less common neuropathic conditions","volume":"68","author":"Snedecor","year":"2014","journal-title":"Int. J. Clin. Pract."},{"key":"10.1016\/j.ejrad.2022.110568_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2020.147219","article-title":"Structural and functional brain abnormalities in postherpetic neuralgia: a systematic review of neuroimaging studies","volume":"1752","author":"Tang","year":"2021","journal-title":"Brain Res."},{"key":"10.1016\/j.ejrad.2022.110568_b0035","doi-asserted-by":"crossref","DOI":"10.2147\/JPR.S183561","article-title":"Altered gray matter volume in patients with herpes zoster and postherpetic neuralgia","volume":"12","author":"Liu","year":"2019","journal-title":"J. Pain Res."},{"key":"10.1016\/j.ejrad.2022.110568_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.117186","article-title":"Deficits in ascending and descending pain modulation pathways in patients with postherpetic neuralgia","volume":"221","author":"Li","year":"2020","journal-title":"NeuroImage"},{"key":"10.1016\/j.ejrad.2022.110568_b0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2021.147608","article-title":"Altered gray matter volume and functional connectivity in patients with herpes zoster and postherpetic neuralgia","volume":"1769","author":"Tang","year":"2021","journal-title":"Brain Res."},{"key":"10.1016\/j.ejrad.2022.110568_b0050","first-page":"E303","article-title":"Abnormal local brain activity beyond the pain matrix in postherpetic neuralgia patients: a resting-state functional MRI study","volume":"20","author":"Cao","year":"2017","journal-title":"Pain Phys."},{"key":"10.1016\/j.ejrad.2022.110568_b0055","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2020.532110","article-title":"Abnormal intrinsic brain activity and neuroimaging-based fmri classification in patients with herpes zoster and postherpetic neuralgia","volume":"11","author":"Huang","year":"2020","journal-title":"Front. Neurol."},{"key":"10.1016\/j.ejrad.2022.110568_b0060","doi-asserted-by":"crossref","first-page":"881","DOI":"10.2147\/JPR.S154314","article-title":"Altered functional connectivity density in patients with herpes zoster and postherpetic neuralgia","volume":"11","author":"Hong","year":"2018","journal-title":"J. Pain Res."},{"issue":"10","key":"10.1016\/j.ejrad.2022.110568_b0065","doi-asserted-by":"crossref","first-page":"2248","DOI":"10.1097\/j.pain.0000000000000634","article-title":"Combined glutamate and glutamine levels in pain-processing brain regions are associated with individual pain sensitivity","volume":"157","author":"Zunhammer","year":"2016","journal-title":"Pain"},{"issue":"11","key":"10.1016\/j.ejrad.2022.110568_b0070","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1177\/0333102414566860","article-title":"Altered neurochemical coupling in the occipital cortex in migraine with visual aura","volume":"35","author":"Bridge","year":"2015","journal-title":"Cephalal.: Int. J. Headache"},{"issue":"5","key":"10.1016\/j.ejrad.2022.110568_b0075","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.acra.2012.02.004","article-title":"Altered excitation-inhibition balance in the brain of patients with diabetic neuropathy","volume":"19","author":"Petrou","year":"2012","journal-title":"Acad. Radiol."},{"issue":"2","key":"10.1016\/j.ejrad.2022.110568_b0080","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1002\/art.33339","article-title":"Reduced insular \u03b3-aminobutyric acid in fibromyalgia","volume":"64","author":"Foerster","year":"2012","journal-title":"Arthrit. Rheum."},{"issue":"1","key":"10.1016\/j.ejrad.2022.110568_b0085","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.mri.2005.10.021","article-title":"N-Acetylaspartate concentrations in the thalami of neuropathic pain patients and healthy comparison subjects measured with (1)H-MRS","volume":"24","author":"Fukui","year":"2006","journal-title":"Magn. Reson. Imag."},{"issue":"4","key":"10.1016\/j.ejrad.2022.110568_b0090","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1002\/jmri.26921","article-title":"Test-retest reliability of the brain metabolites GABA and Glx With JPRESS, PRESS, and MEGA-PRESS MRS sequences in vivo at 3T","volume":"51","author":"Baeshen","year":"2020","journal-title":"J. Magn. Reson. Imag.: JMRI"},{"issue":"12","key":"10.1016\/j.ejrad.2022.110568_b0095","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.4065\/mcp.2011.0305","article-title":"Herpes zoster and postherpetic neuralgia surveillance using structured electronic data","volume":"86","author":"Klompas","year":"2011","journal-title":"Mayo Clin. Proc."},{"key":"10.1016\/j.ejrad.2022.110568_b0100","first-page":"1432","article-title":"Herpes zoster and postherpetic neuralgia: prevention and management","volume":"83","author":"Fashner","year":"2011","journal-title":"Am. Fam. Physician"},{"issue":"4","key":"10.1016\/j.ejrad.2022.110568_b0105","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.ajem.2018.01.008","article-title":"A systematic review of the pain scales in adults: Which to use?","volume":"36","author":"Karcioglu","year":"2018","journal-title":"Am. J. Emerg. Med."},{"issue":"3","key":"10.1016\/j.ejrad.2022.110568_b0110","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1007\/s10548-013-0291-0","article-title":"Individual differences in pain sensitivity vary as a function of precuneus reactivity","volume":"27","author":"Goffaux","year":"2014","journal-title":"Brain Topogr."},{"issue":"7","key":"10.1016\/j.ejrad.2022.110568_b0115","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1002\/nbm.3539","article-title":"Brain \u03b3-aminobutyric acid (GABA) detection in vivo with the J-editing (1) H MRS technique: a comprehensive methodological evaluation of sensitivity enhancement, macromolecule contamination and test-retest reliability","volume":"29","author":"Shungu","year":"2016","journal-title":"NMR Biomed."},{"issue":"6","key":"10.1016\/j.ejrad.2022.110568_b0120","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1002\/jmri.24478","article-title":"Gannet: A batch-processing tool for the quantitative analysis of gamma-aminobutyric acid\u2013edited MR spectroscopy spectra","volume":"40","author":"Edden","year":"2014","journal-title":"J. Magn. Reson. Imag.: JMRI"},{"key":"10.1016\/j.ejrad.2022.110568_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.jneumeth.2020.108827","article-title":"Osprey: Open-source processing, reconstruction & estimation of magnetic resonance spectroscopy data","volume":"343","author":"Oeltzschner","year":"2020","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.ejrad.2022.110568_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.ab.2017.01.017","article-title":"Quality management in in vivo proton MRS","volume":"529","author":"Pedrosa de Barros","year":"2017","journal-title":"Anal. Biochem."},{"issue":"8","key":"10.1016\/j.ejrad.2022.110568_b0135","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1002\/nbm.994","article-title":"Grey and white matter GABA level differences in the human brain using two-dimensional, J-resolved spectroscopic imaging","volume":"18","author":"Jensen","year":"2005","journal-title":"NMR Biomed."},{"issue":"22","key":"10.1016\/j.ejrad.2022.110568_b0140","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1212\/01.wnl.0000313376.07248.28","article-title":"Occipital levels of GABA are related to severe headaches in migraine","volume":"70","author":"Bigal","year":"2008","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.ejrad.2022.110568_b0145","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1146\/annurev-neuro-071013-014030","article-title":"The brain's default mode network","volume":"38","author":"Raichle","year":"2015","journal-title":"Annu. Rev. Neurosci."},{"issue":"1","key":"10.1016\/j.ejrad.2022.110568_b0150","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1146\/annurev-clinpsy-032511-143049","article-title":"Default mode network activity and connectivity in psychopathology","volume":"8","author":"Whitfield-Gabrieli","year":"2012","journal-title":"Ann. Rev. Clin. Psychol."},{"key":"10.1016\/j.ejrad.2022.110568_b0155","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1093\/brain\/awl004","article-title":"The precuneus: a review of its functional anatomy and behavioural correlates","volume":"129","author":"Cavanna","year":"2006","journal-title":"Brain J. Neurol."},{"issue":"47","key":"10.1016\/j.ejrad.2022.110568_b0160","doi-asserted-by":"crossref","first-page":"18566","DOI":"10.1523\/JNEUROSCI.1973-13.2013","article-title":"Resting-state glutamate and GABA concentrations predict task-induced deactivation in the default mode network","volume":"33","author":"Hu","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ejrad.2022.110568_b0165","doi-asserted-by":"crossref","unstructured":"J. Jiang, L. Gu, D. Bao, S. Hong, W. He, Y. Tan, X. Zeng, H. Gong, D. Zhang, F. Zhou, Altered homotopic connectivity in postherpetic neuralgia: a resting state fMRI study, J. Pain Res. 9 (2016) 877-886. <http:\/\/dx.doi.org\/10.2147\/jpr.S117787>.","DOI":"10.2147\/JPR.S117787"},{"issue":"3","key":"10.1016\/j.ejrad.2022.110568_b0170","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1162\/089892903321593117","article-title":"A parametric manipulation of factors affecting task-induced deactivation in functional neuroimaging","volume":"15","author":"McKiernan","year":"2003","journal-title":"J. Cognit. Neurosci."},{"issue":"12","key":"10.1016\/j.ejrad.2022.110568_b0175","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1038\/nn2001","article-title":"GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI","volume":"10","author":"Northoff","year":"2007","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.ejrad.2022.110568_b0180","doi-asserted-by":"crossref","unstructured":"C. Li, Y. Lei, Y. Tian, S. Xu, X. Shen, H. Wu, S. Bao, F. Wang, The etiological contribution of GABAergic plasticity to the pathogenesis of neuropathic pain, Mole. Pain 15 (2019) 1744806919847366. <http:\/\/dx.doi.org\/10.1177\/1744806919847366>.","DOI":"10.1177\/1744806919847366"},{"issue":"1","key":"10.1016\/j.ejrad.2022.110568_b0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11064-013-1199-5","article-title":"A guide to the metabolic pathways and function of metabolites observed in human brain 1H magnetic resonance spectra","volume":"39","author":"Rae","year":"2014","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.ejrad.2022.110568_b0190","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.neulet.2014.03.038","article-title":"Upregulation of glutamatergic transmission in anterior cingulate cortex in the diabetic rats with neuropathic pain","volume":"568","author":"Li","year":"2014","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.ejrad.2022.110568_b0195","doi-asserted-by":"crossref","unstructured":"Z. Wang, S. Huang, X. Yu, L. Li, M. Yang, S. Liang, W. Liu, J. Tao, Altered thalamic neurotransmitters metabolism and functional connectivity during the development of chronic constriction injury induced neuropathic pain, Biol. Res. 53 (2020) 36. <http:\/\/dx.doi.org\/10.1186\/s40659-020-00303-5>.","DOI":"10.1186\/s40659-020-00303-5"},{"issue":"10","key":"10.1016\/j.ejrad.2022.110568_b0200","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1097\/j.pain.0000000000000615","article-title":"Insular balance of glutamatergic and GABAergic signaling modulates pain processing","volume":"157","author":"Watson","year":"2016","journal-title":"Pain"},{"key":"10.1016\/j.ejrad.2022.110568_b0205","doi-asserted-by":"crossref","first-page":"116532","DOI":"10.1016\/j.neuroimage.2020.116532","article-title":"Brain GABA and glutamate levels across pain conditions: a systematic literature review and meta-analysis of 1H-MRS studies using the MRS-Q quality assessment tool","volume":"210","author":"Peek","year":"2020","journal-title":"NeuroImage"},{"issue":"3","key":"10.1016\/j.ejrad.2022.110568_b0210","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1002\/mrm.24391","article-title":"Macromolecule-suppressed GABA-edited magnetic resonance spectroscopy at 3T","volume":"68","author":"Edden","year":"2012","journal-title":"Magn. Reson. Med."},{"issue":"1","key":"10.1016\/j.ejrad.2022.110568_b0215","doi-asserted-by":"crossref","first-page":"e3844","DOI":"10.1002\/nbm.3844","article-title":"Hadamard editing of glutathione and macromolecule-suppressed GABA","volume":"31","author":"Oeltzschner","year":"2018","journal-title":"NMR Biomed."},{"issue":"4","key":"10.1016\/j.ejrad.2022.110568_b0220","first-page":"1591","article-title":"Cerebral biochemical effect of pregabalin in patients with painful diabetic neuropathy: a randomized controlled trial","volume":"9","author":"De Jaeger","year":"2018","journal-title":"DiabetesTher"},{"issue":"1\u20132","key":"10.1016\/j.ejrad.2022.110568_b0225","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.bcp.2005.10.026","article-title":"Amitriptyline prevents thermal hyperalgesia and modifications in rat spinal cord GABA(B) receptor expression and function in an animal model of neuropathic pain","volume":"71","author":"McCarson","year":"2005","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ejrad.2022.110568_b0230","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.neuroscience.2016.06.057","article-title":"Antidepressants and gabapentinoids in neuropathic pain: mechanistic insights","volume":"338","author":"Kremer","year":"2016","journal-title":"Neuroscience"}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X22004181?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X22004181?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T07:31:35Z","timestamp":1759995095000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X22004181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":46,"alternative-id":["S0720048X22004181"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2022.110568","relation":{},"ISSN":["0720-048X"],"issn-type":[{"type":"print","value":"0720-048X"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Elevated GABA level in the precuneus and its association with pain intensity in patients with postherpetic neuralgia: An initial proton magnetic resonance spectroscopy study","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2022.110568","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110568"}}