{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:31:03Z","timestamp":1790353863635,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejradiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.ejrad.2023.110735","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T06:08:15Z","timestamp":1676009295000},"page":"110735","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Automatic classification of MSA subtypes using Whole-brain gray matter function and Structure-Based radiomics approach"],"prefix":"10.1016","volume":"161","author":[{"given":"Boyu","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiachuan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenghao","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dandan","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenzhuo","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo","family":"Guang Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.ejrad.2023.110735_b0005","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/s00702-013-1133-7","article-title":"Cerebellar and parkinsonian phenotypes in multiple system atrophy: similarities, differences and survival","volume":"121","author":"Roncevic","year":"2014","journal-title":"J. Neural Transm. (Vienna)"},{"issue":"6","key":"10.1016\/j.ejrad.2023.110735_b0010","first-page":"670","article-title":"Second consensus statement on the diagnosis of multiple system atrophy","volume":"71","author":"Robertson","year":"2008","journal-title":"Neurology"},{"issue":"5","key":"10.1016\/j.ejrad.2023.110735_b0015","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s00401-006-0109-1","article-title":"Pathology and genetics of multiple system atrophy: an approach to determining genetic susceptibility spectrum","volume":"112","author":"Ozawa","year":"2006","journal-title":"Acta Neuropathol."},{"issue":"1","key":"10.1016\/j.ejrad.2023.110735_b0020","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s40478-020-00950-5","article-title":"Transcriptional profiling of multiple system atrophy cerebellar tissue highlights differences between the parkinsonian and cerebellar sub-types of the disease","volume":"8","author":"Piras","year":"2020","journal-title":"Acta Neuropathol. Commun."},{"issue":"6","key":"10.1016\/j.ejrad.2023.110735_b0025","doi-asserted-by":"crossref","first-page":"4277","DOI":"10.1007\/s00330-020-07521-1","article-title":"Magnetic resonance T1w\/T2w ratio in the middle cerebellar peduncle might be a sensitive biomarker for multiple system atrophy","volume":"31","author":"Sugiyama","year":"2021","journal-title":"Eur. Radiol."},{"issue":"6","key":"10.1016\/j.ejrad.2023.110735_b0030","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/ncn3.125","article-title":"Imaging in multiple system atrophy","volume":"2","author":"Chandran","year":"2015","journal-title":"Neurol. Clin. Neurosci."},{"issue":"1","key":"10.1016\/j.ejrad.2023.110735_b0035","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/s41531-021-00159-w","article-title":"\u201cHot cross bun\u201d is a potential imaging marker for the severity of cerebellar ataxia in MSA-C","volume":"7","author":"Zhu","year":"2021","journal-title":"NPJ Parkinsons Dis"},{"issue":"7","key":"10.1016\/j.ejrad.2023.110735_b0040","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1002\/mdc3.13052","article-title":"Can Autonomic Testing and Imaging Contribute to the Early Diagnosis of Multiple System Atrophy? A Systematic Review and Recommendations by the Movement Disorder Society Multiple System Atrophy Study Group","volume":"7","author":"Pellecchia","year":"2020","journal-title":"Movement Disorders Clinical Practice"},{"issue":"6","key":"10.1016\/j.ejrad.2023.110735_b0045","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s11910-021-01111-4","article-title":"Functional Connectome in Parkinson's Disease and Parkinsonism","volume":"21","author":"Tinaz","year":"2021","journal-title":"Curr. Neurol. Neurosci. Rep."},{"issue":"8","key":"10.1016\/j.ejrad.2023.110735_b0050","first-page":"1390","article-title":"Resting-State Functional MRI: Everything That Nonexperts Have Always Wanted to Know","volume":"39","author":"Lv","year":"2018","journal-title":"AJNR Am. J. Neuroradiol."},{"issue":"5","key":"10.1016\/j.ejrad.2023.110735_b0055","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1093\/cercor\/bhy077","article-title":"Association Between Brain Activation and Functional Connectivity","volume":"29","author":"Tomasi","year":"2019","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.ejrad.2023.110735_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2022.118923","article-title":"Hemodynamic and metabolic correspondence of resting-state voxel-based physiological metrics in healthy adults","volume":"250","author":"Deng","year":"2022","journal-title":"Neuroimage"},{"key":"10.1016\/j.ejrad.2023.110735_b0065","doi-asserted-by":"crossref","first-page":"996","DOI":"10.3389\/fnins.2018.00996","article-title":"Altered Functional Connectivity of Cerebello-Cortical Circuit in Multiple System Atrophy (Cerebellar-Type)","volume":"12","author":"Ren","year":"2018","journal-title":"Front. Neurosci."},{"issue":"16","key":"10.1016\/j.ejrad.2023.110735_b0070","doi-asserted-by":"crossref","first-page":"16341","DOI":"10.18632\/aging.103676","article-title":"Abnormal static and dynamic functional connectivity of resting-state fMRI in multiple system atrophy","volume":"12","author":"Zheng","year":"2020","journal-title":"Aging (Albany NY)"},{"key":"10.1016\/j.ejrad.2023.110735_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2019.101891","article-title":"Cerebellar atrophy and its contribution to motor and cognitive performance in multiple system atrophy","volume":"23","author":"Yang","year":"2019","journal-title":"Neuroimage Clin"},{"issue":"1","key":"10.1016\/j.ejrad.2023.110735_b0080","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.clinph.2019.09.026","article-title":"Altered resting-state voxel-level whole-brain functional connectivity in multiple system atrophy patients with cognitive impairment","volume":"131","author":"Yang","year":"2020","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.ejrad.2023.110735_b0085","doi-asserted-by":"crossref","DOI":"10.1007\/s11682-019-00097-5","article-title":"Altered functional connectivity of dentate nucleus in parkinsonian and cerebellar variants of multiple system atrophy","author":"Yang","year":"2019","journal-title":"Brain Imaging Behav."},{"key":"10.1016\/j.ejrad.2023.110735_b0090","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.neuroimage.2017.11.025","article-title":"A comprehensive analysis of resting state fMRI measures to classify individual patients with Alzheimer's disease","volume":"167","author":"de Vos","year":"2018","journal-title":"Neuroimage"},{"key":"10.1016\/j.ejrad.2023.110735_b0095","doi-asserted-by":"crossref","first-page":"751","DOI":"10.3389\/fnins.2020.00751","article-title":"A Radiomics Approach to Predicting Parkinson's Disease by Incorporating Whole-Brain Functional Activity and Gray Matter Structure","volume":"14","author":"Cao","year":"2020","journal-title":"Front. Neurosci."},{"issue":"5","key":"10.1016\/j.ejrad.2023.110735_b0100","doi-asserted-by":"crossref","first-page":"e02103","DOI":"10.1002\/brb3.2103","article-title":"Aberrant functional connectivity and activity in Parkinson's disease and comorbidity with depression based on radiomic analysis","volume":"11","author":"Zhang","year":"2021","journal-title":"Brain Behav."},{"issue":"12","key":"10.1016\/j.ejrad.2023.110735_b0105","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1002\/mds.20255","article-title":"Development and validation of the Unified Multiple System Atrophy Rating Scale (UMSARS)","volume":"19","author":"Wenning","year":"2004","journal-title":"Mov. Disord."},{"issue":"13","key":"10.1016\/j.ejrad.2023.110735_b0110","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1002\/mds.25181","article-title":"The Unified Multiple System Atrophy Rating Scale: intrarater reliability","volume":"27","author":"Krismer","year":"2012","journal-title":"Mov. Disord."},{"key":"10.1016\/j.ejrad.2023.110735_b0115","article-title":"Regression Shrinkage and Selection via the Lasso","author":"Robert and Tibshirani","year":"1996","journal-title":"J. Roy. Stat. Soc.: Ser. B (Methodol.)"},{"issue":"3","key":"10.1016\/j.ejrad.2023.110735_b0120","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2307\/2531595","article-title":"Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach","volume":"44","author":"DeLong","year":"1988","journal-title":"Biometrics"},{"key":"10.1016\/j.ejrad.2023.110735_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2019.101720","article-title":"Cerebellar resting-state functional connectivity in Parkinson's disease and multiple system atrophy: Characterization of abnormalities and potential for differential diagnosis at the single-patient level","volume":"22","author":"Baggio","year":"2019","journal-title":"Neuroimage Clin"},{"issue":"2","key":"10.1016\/j.ejrad.2023.110735_b0130","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1002\/mds.28348","article-title":"Automated Categorization of Parkinsonian Syndromes Using Magnetic Resonance Imaging in a Clinical Setting","volume":"36","author":"Chougar","year":"2021","journal-title":"Mov. Disord."},{"key":"10.1016\/j.ejrad.2023.110735_b0135","doi-asserted-by":"crossref","DOI":"10.1002\/mds.21839","article-title":"Survival in multiple system atrophy","author":"Schrag","year":"2008","journal-title":"Mov. Disord."},{"issue":"3","key":"10.1016\/j.ejrad.2023.110735_b0140","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s00259-015-3191-6","article-title":"Different loss of dopamine transporter according to subtype of multiple system atrophy","volume":"43","author":"Kim","year":"2016","journal-title":"Eur. J. Nucl. Med. Mol. Imaging"},{"issue":"2","key":"10.1016\/j.ejrad.2023.110735_b0145","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/ane.12932","article-title":"Patterns of dopamine transporter imaging in subtypes of multiple system atrophy","volume":"138","author":"Bu","year":"2018","journal-title":"Acta Neurol. Scand."},{"issue":"6","key":"10.1016\/j.ejrad.2023.110735_b0150","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1007\/s11682-019-00097-5","article-title":"Altered functional connectivity of dentate nucleus in parkinsonian and cerebellar variants of multiple system atrophy","volume":"13","author":"Yang","year":"2019","journal-title":"Brain Imaging Behav."},{"key":"10.1016\/j.ejrad.2023.110735_b0155","doi-asserted-by":"crossref","unstructured":"Rosskopf, J., et al., Hyperconnective and hypoconnective cortical and subcortical functional networks in multiple system atrophy. Parkinsonism & Related Disorders, 2018: p. S1353802018300105.","DOI":"10.1016\/j.parkreldis.2018.01.012"},{"issue":"5","key":"10.1016\/j.ejrad.2023.110735_b0160","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1007\/s00415-020-09702-w","article-title":"Brain MRI of multiple system atrophy of cerebellar type: a prospective study with implications for diagnosis criteria","volume":"267","author":"Carre","year":"2020","journal-title":"J. Neurol."},{"key":"10.1016\/j.ejrad.2023.110735_b0165","article-title":"Altered Functional Connectivity of Cerebello-Cortical Circuit in Multiple System Atrophy (Cerebellar-Type)","volume":"12","author":"Shan","year":"2019","journal-title":"Front. Neurosci."},{"issue":"1","key":"10.1016\/j.ejrad.2023.110735_b0170","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1176\/appi.ajp.161.1.99","article-title":"Anterior Cingulate, Gyrus Rectus, and Orbitofrontal Abnormalities in Elderly Depressed Patients: An MRI-Based Parcellation of the Prefrontal Cortex","volume":"161","author":"Ballmaier","year":"2004","journal-title":"Am. J. Psychiatry"},{"issue":"6","key":"10.1016\/j.ejrad.2023.110735_b0175","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/scan\/nsy032","article-title":"Functional connectivity of the human amygdala in health and in depression","volume":"13","author":"Cheng","year":"2018","journal-title":"Soc. Cogn. Affect. Neurosci."},{"issue":"1","key":"10.1016\/j.ejrad.2023.110735_b0180","first-page":"11","article-title":"Frontal lobe function, behavioral changes and quality of life in patients with multiple system atrophy","volume":"37","author":"Zhang","year":"2019","journal-title":"Restor. Neurol. Neurosci."},{"issue":"Pt 8","key":"10.1016\/j.ejrad.2023.110735_b0185","doi-asserted-by":"crossref","first-page":"2382","DOI":"10.1093\/brain\/awq158","article-title":"Cognitive impairment in patients with multiple system atrophy and progressive supranuclear palsy","volume":"133","author":"Brown","year":"2010","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.ejrad.2023.110735_b0190","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s12311-017-0911-4","article-title":"Crus I in the Rodent Cerebellum: Its Homology to Crus I and II in the Primate Cerebellum and Its Anatomical Uniqueness Among Neighboring Lobules","volume":"17","author":"Sugihara","year":"2018","journal-title":"Cerebellum"},{"issue":"3","key":"10.1016\/j.ejrad.2023.110735_b0195","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1016\/j.neuroimage.2009.10.045","article-title":"Evolution of the cerebellar cortex: the selective expansion of prefrontal-projecting cerebellar lobules","volume":"49","author":"Balsters","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.ejrad.2023.110735_b0200","doi-asserted-by":"crossref","unstructured":"A cross-sectional multicenter study of cognitive and behavioural features in multiple system atrophy patients of the parkinsonian and cerebellar type. J. Neural Transmiss. 2013. 120(4): p. 613-618.","DOI":"10.1007\/s00702-013-0997-x"},{"issue":"1","key":"10.1016\/j.ejrad.2023.110735_b0205","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/s00401-015-1442-z","article-title":"Atypical multiple system atrophy is a new subtype of frontotemporal lobar degeneration: frontotemporal lobar degeneration associated with \u03b1-synuclein","volume":"130","author":"Aoki","year":"2015","journal-title":"Acta Neuropathol."},{"issue":"6","key":"10.1016\/j.ejrad.2023.110735_b0210","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1093\/brain\/awaa126","article-title":"Hippocampal alpha-synuclein pathology correlates with memory impairment in multiple system atrophy","volume":"143","author":"Miki","year":"2020","journal-title":"Brain"},{"issue":"2","key":"10.1016\/j.ejrad.2023.110735_b0215","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1007\/s00330-018-5594-9","article-title":"Abnormalities of white and grey matter in early multiple system atrophy: comparison of parkinsonian and cerebellar variants","volume":"29","author":"Dash","year":"2019","journal-title":"Eur. Radiol."}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X23000499?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X23000499?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T07:34:10Z","timestamp":1759995250000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X23000499"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":43,"alternative-id":["S0720048X23000499"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2023.110735","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Automatic classification of MSA subtypes using Whole-brain gray matter function and Structure-Based radiomics approach","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2023.110735","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"110735"}}