{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:57:07Z","timestamp":1790629027865,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejradiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.ejrad.2023.110802","type":"journal-article","created":{"date-parts":[[2023,3,26]],"date-time":"2023-03-26T09:51:22Z","timestamp":1679824282000},"page":"110802","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Whole body MRI with DWI in people with NF1 and Schwannomatosis: Are qualitative and quantitative imaging features of peripheral lesions comparable to localized MRI?"],"prefix":"10.1016","volume":"162","author":[{"given":"Patrick","family":"Debs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura M.","family":"Fayad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos G.","family":"Romo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivani","family":"Ahlawat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2023.110802_b0005","article-title":"Neurofibromatosis: A Review of NF1, NF2, and Schwannomatosis","volume":"05","author":"Kresak","year":"2016","journal-title":"J. Pediatr. Genet."},{"key":"10.1016\/j.ejrad.2023.110802_b0010","doi-asserted-by":"crossref","first-page":"17004","DOI":"10.1038\/nrdp.2017.4","article-title":"Neurofibromatosis type 1","volume":"3","author":"Gutmann","year":"2017","journal-title":"Nat. Rev. Dis. Primers."},{"key":"10.1016\/j.ejrad.2023.110802_b0015","doi-asserted-by":"crossref","DOI":"10.1038\/jid.2014.465","article-title":"Incidence and mortality of neurofibromatosis: A total population study in Finland","volume":"135","author":"Uusitalo","year":"2015","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.ejrad.2023.110802_b0020","doi-asserted-by":"crossref","DOI":"10.4103\/0028-3886.250697","article-title":"Peripheral nerve tumors in neurofibromatosis 1: An overview on management and indications for surgical treatment in our experience","volume":"67","author":"Garozzo","year":"2019","journal-title":"Neurol. India."},{"key":"10.1016\/j.ejrad.2023.110802_b0025","doi-asserted-by":"crossref","DOI":"10.1186\/1750-1172-4-16","article-title":"Neurofibromatosis type 2 (NF2): A clinical and molecular review","volume":"4","author":"Evans","year":"2009","journal-title":"Orphanet. J. Rare Dis."},{"key":"10.1016\/j.ejrad.2023.110802_b0030","doi-asserted-by":"crossref","unstructured":"S.R. Plotkin, J.O. Blakeley, D.G. Evans, C.O. Hanemann, T.J.M. Hulsebos, K. Hunter-Schaedle, G. v. Kalpana, B. Korf, L. Messiaen, L. Papi, N. Ratner, L.S. Sherman, M.J. Smith, A.O. Stemmer-Rachamimov, J. Vitte, M. Giovannini, Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria, in: Am. J. Med. Genet. A, 2013. Doi: 10.1002\/ajmg.a.35760.","DOI":"10.1002\/ajmg.a.35760"},{"key":"10.1016\/j.ejrad.2023.110802_b0035","doi-asserted-by":"crossref","DOI":"10.1634\/theoncologist.2012-0162","article-title":"Clinical Features of Schwannomatosis: A Retrospective Analysis of 87 Patients","volume":"17","author":"Merker","year":"2012","journal-title":"Oncologist."},{"key":"10.1016\/j.ejrad.2023.110802_b0040","doi-asserted-by":"crossref","DOI":"10.2214\/AJR.12.8577","article-title":"Schwannomatosis: The overlooked neurofibromatosis?","volume":"200","author":"Koontz","year":"2013","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/j.ejrad.2023.110802_b0045","doi-asserted-by":"crossref","DOI":"10.3171\/2010.8.JNS091900","article-title":"Schwannomatosis, sporadic schwannomatosis, and familial schwannomatosis: A surgical series with long-term follow-up: Clinical article","volume":"114","author":"Gonzalvo","year":"2011","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.ejrad.2023.110802_b0050","article-title":"What to know about schwannomatosis: a literature review","author":"Schraepen","year":"2020","journal-title":"Br. J. Neurosurg."},{"key":"10.1016\/j.ejrad.2023.110802_b0055","doi-asserted-by":"crossref","unstructured":"S.R. Plotkin, L. Messiaen, E. Legius, P. Pancza, R.A. Avery, J.O. Blakeley, D. Babovic-Vuksanovic, R. Ferner, M.J. Fisher, J.M. Friedman, M. Giovannini, D.H. Gutmann, C.O. Hanemann, M. Kalamarides, H. Kehrer-Sawatzki, B.R. Korf, V.-F. Mautner, M. MacCollin, L. Papi, K.A. Rauen, V. Riccardi, E. Schorry, M.J. Smith, A. Stemmer-Rachamimov, D.A. Stevenson, N.J. Ullrich, D. Viskochil, K. Wimmer, K. Yohay, International Consensus Group on Neurofibromatosis Diagnostic Criteria (I-NF-DC), S.M. Huson, P. Wolkenstein, D.G. Evans, Updated diagnostic criteria and nomenclature for neurofibromatosis type 2 and schwannomatosis: An international consensus recommendation, Genet. Med. (2022). Doi: 10.1016\/J.GIM.2022.05.007.","DOI":"10.1212\/WNL.98.18_supplement.3996"},{"key":"10.1016\/j.ejrad.2023.110802_b0060","doi-asserted-by":"crossref","DOI":"10.1215\/15228517-2008-011","article-title":"Assessment of benign tumor burden by whole-body MRI in patients with neurofibromatosis 1","volume":"10","author":"Mautner","year":"2008","journal-title":"Neuro Oncol."},{"key":"10.1016\/j.ejrad.2023.110802_b0065","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0000000000002929","article-title":"Current whole-body MRI applications in the neurofibromatoses","volume":"87","author":"Ahlawat","year":"2016","journal-title":"Neurology"},{"key":"10.1016\/j.ejrad.2023.110802_b0070","doi-asserted-by":"crossref","DOI":"10.1212\/01.WNL.0000163982.78900.AD","article-title":"Diagnostic criteria for schwannomatosis","volume":"64","author":"MacCollin","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.ejrad.2023.110802_b0075","doi-asserted-by":"crossref","DOI":"10.1212\/01.WNL.0000035638.74084.F4","article-title":"Evaluation of clinical diagnostic criteria for neurofibromatosis 2","volume":"59","author":"Baser","year":"2002","journal-title":"Neurology"},{"key":"10.1016\/j.ejrad.2023.110802_b0080","doi-asserted-by":"crossref","DOI":"10.1007\/s00256-019-03290-1","article-title":"Current status and recommendations for imaging in neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis","volume":"49","author":"Ahlawat","year":"2020","journal-title":"Skeletal Radiol."},{"key":"10.1016\/j.ejrad.2023.110802_b0085","doi-asserted-by":"crossref","DOI":"10.1148\/rg.345140190","article-title":"Diffusion-weighted MR imaging for characterizing musculoskeletal lesions","volume":"34","author":"Subhawong","year":"2014","journal-title":"Radiographics."},{"key":"10.1016\/j.ejrad.2023.110802_b0090","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.12111740","article-title":"Musculoskeletal tumors: How to use anatomic, functional, and metabolic MR techniques","volume":"265","author":"Fayad","year":"2012","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2023.110802_b0095","doi-asserted-by":"crossref","DOI":"10.1148\/radiology.168.2.3393671","article-title":"Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging","volume":"168","author":"le Bihan","year":"1988","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2023.110802_b0100","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.2015142463","article-title":"Multiparametric assessment of treatment response in high-grade soft-tissue sarcomas with anatomic and functional MR imaging sequences","volume":"278","author":"Soldatos","year":"2016","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2023.110802_b0105","doi-asserted-by":"crossref","DOI":"10.1002\/jmri.24994","article-title":"Interobserver variability of selective region-of-interest measurement protocols for quantitative diffusion weighted imaging in soft tissue masses: Comparison with whole tumor volume measurements","volume":"43","author":"Ahlawat","year":"2016","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.ejrad.2023.110802_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2018.03.018","article-title":"Imaging cellularity in benign and malignant peripheral nerve sheath tumors: Utility of the \u201ctarget sign\u201d by diffusion weighted imaging","volume":"102","author":"Ahlawat","year":"2018","journal-title":"Eur. J. Radiol."},{"key":"10.1016\/j.ejrad.2023.110802_b0115","doi-asserted-by":"crossref","DOI":"10.3174\/ajnr.A3910","article-title":"Conventional and functional MR imaging of peripheral nerve sheath tumors: Initial experience","volume":"35","author":"Demehri","year":"2014","journal-title":"Am. J. Neuroradiol."},{"key":"10.1016\/j.ejrad.2023.110802_b0120","doi-asserted-by":"crossref","DOI":"10.1053\/j.ro.2022.01.008","article-title":"MR Neurography of Peripheral Nerve Tumors and Tumor-Mimics","author":"Debs","year":"2022","journal-title":"Semin. Roentgenol."},{"key":"10.1016\/j.ejrad.2023.110802_b0125","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.2343030946","article-title":"The target sign: Extremity","volume":"234","author":"Banks","year":"2005","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2023.110802_b0130","doi-asserted-by":"crossref","DOI":"10.1148\/radiology.202.1.8988186","article-title":"Assessing contrast on MR images","volume":"202","author":"Wolff","year":"1997","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2023.110802_b0135","doi-asserted-by":"crossref","DOI":"10.1007\/s00256-016-2348-0","article-title":"Three-dimensional volumetric MRI with isotropic resolution: improved speed of acquisition, spatial resolution and assessment of lesion conspicuity in patients with recurrent soft tissue sarcoma","volume":"45","author":"Ahlawat","year":"2016","journal-title":"Skeletal Radiol."},{"key":"10.1016\/j.ejrad.2023.110802_b0140","doi-asserted-by":"crossref","DOI":"10.1007\/s00330-020-07394-4","article-title":"Determination of skeletal tumor extent: is an isotropic T1-weighted 3D sequence adequate?","volume":"31","author":"Luna","year":"2021","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.ejrad.2023.110802_b0145","doi-asserted-by":"crossref","DOI":"10.1002\/jmri.25236","article-title":"Multiparametric whole-body anatomic, functional, and metabolic imaging characteristics of peripheral lesions in patients with schwannomatosis","volume":"44","author":"Ahlawat","year":"2016","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.ejrad.2023.110802_b0150","doi-asserted-by":"crossref","DOI":"10.1212\/WNL.0000000000008092","article-title":"Imaging biomarkers for malignant peripheral nerve sheath tumors in neurofibromatosis type 1","volume":"93","author":"Ahlawat","year":"2019","journal-title":"Neurology"},{"key":"10.1016\/j.ejrad.2023.110802_b0155","doi-asserted-by":"crossref","DOI":"10.5402\/2013\/627932","article-title":"Whole Body MRI at 3T with Quantitative Diffusion Weighted Imaging and Contrast-Enhanced Sequences for the Characterization of Peripheral Lesions in Patients with Neurofibromatosis Type 2 and Schwannomatosis","volume":"2013","author":"Fayad","year":"2013","journal-title":"ISRN Radiol."},{"key":"10.1016\/j.ejrad.2023.110802_b0160","doi-asserted-by":"crossref","DOI":"10.1093\/neuonc\/noaa053","article-title":"Longitudinal evaluation of peripheral nerve sheath tumors in neurofibromatosis type 1: growth analysis of plexiform neurofibromas and distinct nodular lesions","volume":"22","author":"Akshintala","year":"2020","journal-title":"Neuro Oncol."},{"key":"10.1016\/j.ejrad.2023.110802_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.acra.2017.09.004","article-title":"Volumetric MRI Analysis of Plexiform Neurofibromas in Neurofibromatosis Type 1: Comparison of Two Methods","volume":"25","author":"Cai","year":"2018","journal-title":"Acad. Radiol."},{"key":"10.1016\/j.ejrad.2023.110802_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.carj.2010.04.009","article-title":"Pictorial essay: Imaging of peripheral nerve sheath tumours","volume":"62","author":"Chee","year":"2011","journal-title":"Can. Assoc. Radiol. J."},{"key":"10.1016\/j.ejrad.2023.110802_b0175","doi-asserted-by":"crossref","DOI":"10.1007\/s002470050082","article-title":"MR imaging differentiation of benign and malignant peripheral nerve sheath tumors: Use of the target sign","volume":"27","author":"Bhargava","year":"1997","journal-title":"Pediatr. Radiol."},{"key":"10.1016\/j.ejrad.2023.110802_b0180","doi-asserted-by":"crossref","DOI":"10.2214\/AJR.09.2724","article-title":"MRI features in the differentiation of malignant peripheral nerve sheath tumors and neurofibromas","volume":"194","author":"Wasa","year":"2010","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/j.ejrad.2023.110802_b0185","article-title":"Telltale signs of peripheral neurogenic tumors on magnetic resonance imaging","volume":"25","author":"Kakkar","year":"2015","journal-title":"Indian J. Radiol. Imaging."},{"key":"10.1016\/j.ejrad.2023.110802_b0190","doi-asserted-by":"crossref","DOI":"10.1002\/jmri.20969","article-title":"Measurement of signal-to-noise ratios in MR images: Influence of multichannel coils, parallel imaging, and reconstruction filters","volume":"26","author":"Dietrich","year":"2007","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.ejrad.2023.110802_b0195","doi-asserted-by":"crossref","DOI":"10.1002\/jmri.20931","article-title":"Soft-tissue tumors evaluated by line-scan diffusion-weighted imaging: Influence of myxoid matrix on the apparent diffusion coefficient","volume":"25","author":"Maeda","year":"2007","journal-title":"J. Magn. Reson. Imaging"},{"key":"10.1016\/j.ejrad.2023.110802_b0200","doi-asserted-by":"crossref","unstructured":"M. Wennmann, H. Thierjung, F. Bauer, V. Weru, T. Hielscher, M. Gr\u00f6zinger, R. Gnirs, S. Sauer, H. Goldschmidt, N. Weinhold, D. Bonekamp, H.-P. Schlemmer, T.F. Weber, S. Delorme, L.T. Rotkopf, Repeatability and Reproducibility of ADC Measurements and MRI Signal Intensity Measurements of Bone Marrow in Monoclonal Plasma Cell Disorders: A Prospective Bi-institutional Multiscanner, Multiprotocol Study., Invest Radiol. (2021). Doi: 10.1097\/RLI.0000000000000838.","DOI":"10.1097\/RLI.0000000000000838"}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X2300116X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X2300116X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T07:38:26Z","timestamp":1759995506000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X2300116X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":40,"alternative-id":["S0720048X2300116X"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2023.110802","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Whole body MRI with DWI in people with NF1 and Schwannomatosis: Are qualitative and quantitative imaging features of peripheral lesions comparable to localized MRI?","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2023.110802","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110802"}}