{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T01:31:42Z","timestamp":1792200702117,"version":"4.4.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejradiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.ejrad.2023.110897","type":"journal-article","created":{"date-parts":[[2023,5,29]],"date-time":"2023-05-29T11:34:15Z","timestamp":1685360055000},"page":"110897","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Multivariable stratification of PI-RADS version 2.1 categories for the risk of false-positive target biopsy: Impact on prostate biopsy decisions"],"prefix":"10.1016","volume":"165","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0904-5147","authenticated-orcid":false,"given":"Rossano","family":"Girometti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Giannarini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"De Martino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Caregnato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Cereser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matteo","family":"Soligo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Rozze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Pizzolitto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Isola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Zuiani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2023.110897_b0005","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1056\/NEJMoa1801993","article-title":"MRI-targeted or standard biopsy for prostate-cancer diagnosis","volume":"378","author":"Kasivisvanathan","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ejrad.2023.110897_b0010","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.eururo.2020.03.048","article-title":"Negative predictive value of multiparametric magnetic resonance imaging in the detection of clinically significant prostate cancer in the prostate imaging reporting and data system era: a systematic review and meta-analysis","volume":"78","author":"Sathianathen","year":"2020","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0015","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.eururo.2019.06.023","article-title":"Prostate magnetic resonance imaging, with or without magnetic resonance imaging-targeted biopsy, and systematic biopsy for detecting prostate cancer: a cochrane systematic review and meta-analysis","volume":"77","author":"Drost","year":"2020","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0020","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.eururo.2020.10.013","article-title":"Restricting false-positive magnetic resonance imaging scans to reduce overdiagnosis of prostate cancer","volume":"79","author":"Bangma","year":"2021","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0025","first-page":"697","article-title":"Positive predictive value of prostate imaging reporting and data system version 2 for the detection of clinically significant prostate cancer: a systematic review and meta-analysis, european urology","volume":"4","author":"Mazzone","year":"2021","journal-title":"Oncology"},{"key":"10.1016\/j.ejrad.2023.110897_b0030","doi-asserted-by":"crossref","first-page":"847","DOI":"10.2214\/AJR.18.20571","article-title":"A systematic review of the existing prostate imaging reporting and data system version 2 (PI-RADSv2) literature and subset meta-analysis of PI-RADSv2 categories stratified by Gleason Scores","volume":"212","author":"Barkovich","year":"2019","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/j.ejrad.2023.110897_b0035","doi-asserted-by":"crossref","first-page":"70","DOI":"10.21037\/tau.2017.12.31","article-title":"MRI in early prostate cancer detection: how to manage indeterminate or equivocal PI-RADS 3 lesions?","volume":"7","author":"Schoots","year":"2018","journal-title":"Transl. Androl. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0040","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/s41391-021-00417-1","article-title":"Cancer detection rates of the PI-RADSv2.1 assessment categories: systematic review and meta-analysis on lesion level and patient level","volume":"25","author":"Oerther","year":"2022","journal-title":"Prostate Cancer Prostatic Dis."},{"key":"10.1016\/j.ejrad.2023.110897_b0045","doi-asserted-by":"crossref","first-page":"20191050","DOI":"10.1259\/bjr.20191050","article-title":"Impact of PI-RADS Category 3 lesions on the diagnostic accuracy of MRI for detecting prostate cancer and the prevalence of prostate cancer within each PI-RADS category: A systematic review and meta-analysis","volume":"94","author":"Wadera","year":"2021","journal-title":"BJR."},{"key":"10.1016\/j.ejrad.2023.110897_b0050","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.3390\/ijms20071637","article-title":"Prediction medicine: biomarkers risk calculators and magnetic resonance imaging as risk stratification tools in prostate cancer diagnosis","volume":"20","author":"Osses","year":"2019","journal-title":"IJMS"},{"key":"10.1016\/j.ejrad.2023.110897_b0055","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/bju.15277","article-title":"Risk-adapted biopsy decision based on prostate magnetic resonance imaging and prostate-specific antigen density for enhanced biopsy avoidance in first prostate cancer diagnostic evaluation","volume":"127","author":"Schoots","year":"2021","journal-title":"BJU Int."},{"key":"10.1016\/j.ejrad.2023.110897_b0060","doi-asserted-by":"crossref","unstructured":"A. Alberts, M. Roobol, F.J. Drost, G. Van Leenders, L. Bokhorst, C.H. Bangma, I.G. Schoots, PSA-density based patient selection for MRI-targeted prostate biopsy could reduce unnecessary biopsy procedures in men on active surveillance for low-grade prostate cancer, Eur. Urol. Suppl. 16 (2017) e856\u2013e858.","DOI":"10.1016\/S1569-9056(17)30555-9"},{"key":"10.1016\/j.ejrad.2023.110897_b0065","doi-asserted-by":"crossref","first-page":"20210886","DOI":"10.1259\/bjr.20210886","article-title":"Comparison of different thresholds of PSA density for risk stratification of PI-RADSv2.1 categories on prostate MRI","volume":"95","author":"Girometti","year":"2022","journal-title":"BJR."},{"key":"10.1016\/j.ejrad.2023.110897_b0070","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.eururo.2020.09.043","article-title":"False Positive Multiparametric Magnetic Resonance Imaging Phenotypes in the Biopsy-na\u00efve Prostate: Are They Distinct from Significant Cancer-associated Lesions? Lessons from PROMIS","volume":"79","author":"Stavrinides","year":"2021","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0075","doi-asserted-by":"crossref","first-page":"574","DOI":"10.21037\/tau.2019.12.42","article-title":"Establishing a novel prediction model for improving the positive rate of prostate biopsy","volume":"9","author":"Tao","year":"2020","journal-title":"Transl. Androl. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0080","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1002\/jmri.27491","article-title":"Ancillary imaging and clinical features for the characterization of prostate lesions: A proposed approach to reduce false positives","volume":"53","author":"Lee","year":"2021","journal-title":"Magn. Reson. Imaging"},{"key":"10.1016\/j.ejrad.2023.110897_b0085","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.eururo.2020.09.042","article-title":"EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer\u20142020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent","volume":"79","author":"Mottet","year":"2021","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0090","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1007\/s00261-021-03023-w","article-title":"Assessment of prostate imaging reporting and data system version 2.1 false-positive category 4 and 5 lesions in clinically significant prostate cancer","volume":"46","author":"Wang","year":"2021","journal-title":"Abdom. Radiol."},{"issue":"2019","key":"10.1016\/j.ejrad.2023.110897_b0095","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.eururo.2019.02.033","article-title":"Update of prostate imaging reporting and data system version 2","volume":"76","author":"Turkbey","year":"2019","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0100","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12916-014-0241-z","article-title":"Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD Statement","volume":"13","author":"Collins","year":"2015","journal-title":"BMC Med"},{"key":"10.1016\/j.ejrad.2023.110897_b0105","series-title":"Clinical prediction models: A practical approach to development, validation, and updating","first-page":"255","article-title":"Evaluation of performance","author":"Steyeberg","year":"2019"},{"key":"10.1016\/j.ejrad.2023.110897_b0110","doi-asserted-by":"crossref","first-page":"5787","DOI":"10.1007\/s00330-022-08685-8","article-title":"Decision curve analysis in the evaluation of radiology research","volume":"32","author":"Vickers","year":"2022","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.ejrad.2023.110897_b0115","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.eururo.2018.03.007","article-title":"Negative multiparametric magnetic resonance imaging for prostate cancer: what\u2019s next?","volume":"74","author":"Panebianco","year":"2018","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0120","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1007\/s00345-019-02707-9","article-title":"Multivariate risk prediction tools including MRI for individualized biopsy decision in prostate cancer diagnosis: current status and future directions","volume":"38","author":"Schoots","year":"2020","journal-title":"World J. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0125","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/j.eururo.2022.07.022","volume":"82","author":"Peters","year":"2022","journal-title":"Eur. Urol."},{"key":"10.1016\/j.ejrad.2023.110897_b0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11934-022-01084-y","article-title":"Interobserver agreement and accuracy in interpreting mpMRI of the prostate: a systematic review","volume":"23","author":"Annamalai","year":"2022","journal-title":"Curr. Urol. Rep."},{"key":"10.1016\/j.ejrad.2023.110897_b0135","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2214\/AJR.20.24268","article-title":"PI-RADS Committee Position on MRI without contrast medium in biopsy-naive men with suspected prostate cancer: narrative review","volume":"216","author":"Schoots","year":"2021","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/j.ejrad.2023.110897_b0140","first-page":"308","article-title":"Bioptic prostatic inflammation correlates with false positive rates of multiparametric magnetic resonance imaging in detecting clinically significant prostate cancer, Cent European","volume":"74","author":"Falagario","year":"2021","journal-title":"J Urol."},{"issue":"636","key":"10.1016\/j.ejrad.2023.110897_b0145","first-page":"e7","article-title":"Histomorphological analysis of false positive PI-RADS 4 and 5 lesions","volume":"38","author":"Hupe","year":"2020","journal-title":"Urol. Oncol.: Seminars Original Invest."},{"key":"10.1016\/j.ejrad.2023.110897_b0150","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.euo.2019.05.006","article-title":"Assessing the clinical value of positive multiparametric magnetic resonance imaging in young men with a suspicion of prostate cancer","volume":"4","author":"Stabile","year":"2021","journal-title":"Eur. Urol. Oncol."},{"key":"10.1016\/j.ejrad.2023.110897_b0155","doi-asserted-by":"crossref","first-page":"145","DOI":"10.2147\/RRU.S169017","article-title":"Reduced sensitivity of multiparametric MRI for clinically significant prostate cancer in men under the age of 50","volume":"10","author":"Gielchinsky","year":"2018","journal-title":"RRU."},{"key":"10.1016\/j.ejrad.2023.110897_b0160","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.eururo.2022.07.025","article-title":"Prostate cancer detection percentages of repeat biopsy in patients with positive multiparametric magnetic resonance imaging (Prostate Imaging Reporting and Data System\/Likert 3\u20135) and negative initial biopsy. A Mini Systematic Review","volume":"82","author":"Grivas","year":"2022","journal-title":"Eur. Urol."}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X23002115?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X23002115?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T07:38:21Z","timestamp":1759995501000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X23002115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":32,"alternative-id":["S0720048X23002115"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2023.110897","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multivariable stratification of PI-RADS version 2.1 categories for the risk of false-positive target biopsy: Impact on prostate biopsy decisions","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2023.110897","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110897"}}