{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:05:39Z","timestamp":1780499139632,"version":"3.54.1"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","ejradiology.com","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.ejrad.2023.111263","type":"journal-article","created":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T20:31:32Z","timestamp":1702326692000},"page":"111263","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Prospective evaluation of MR-TRG (Tumor Regression Grade) in esophageal cancer after neo-adjuvant therapy: Preliminary results"],"prefix":"10.1016","volume":"171","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-7449-999X","authenticated-orcid":false,"given":"Pauline","family":"Chapellier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Fasquelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Saglietti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9my","family":"Kinj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Styliani","family":"Mantziari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Sch\u00e4fer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Haefliger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Jreige","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na\u00efk","family":"Vietti Violi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Sempoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2999-1958","authenticated-orcid":false,"given":"Clarisse","family":"Dromain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2023.111263_b0005","series-title":"Cancer Incidence in Five Continents, CI5plus: IARC CancerBase No","author":"Ferlay","year":"2018"},{"issue":"1","key":"10.1016\/j.ejrad.2023.111263_b0010","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/1759-7714.14745","article-title":"Epidemiology of esophageal cancer in 2020 and projections to 2030 and 2040","volume":"14","author":"Liu","year":"2023","journal-title":"Thorac Cancer. Janv"},{"issue":"15","key":"10.1016\/j.ejrad.2023.111263_b0015","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1016\/j.ejca.2013.05.029","article-title":"Preoperative chemo(radio)therapy versus primary surgery for gastroesophageal adenocarcinoma: systematic review with meta-analysis combining individual patient and aggregate data","volume":"49","author":"Ronellenfitsch","year":"1990","journal-title":"Eur J Cancer Oxf Engl"},{"issue":"5","key":"10.1016\/j.ejrad.2023.111263_b0020","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1097\/SLA.0000000000005617","article-title":"CROSS Versus FLOT Regimens in Esophageal and Esophagogastric Junction Adenocarcinoma: A Propensity-Matched Comparison","volume":"276","author":"Donlon","year":"2022","journal-title":"Ann Surg."},{"key":"10.1016\/j.ejrad.2023.111263_b0025","doi-asserted-by":"crossref","unstructured":"Eyck BM, Van Lanschot JJB, Hulshof MCCM, Van Der Wilk BJ, Shapiro J, Van Hagen P, et al. Ten-Year Outcome of Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer: The Randomized Controlled CROSS Trial. J Clin Oncol. 20 juin 2021;39(18):1995\u20132004.","DOI":"10.1200\/JCO.20.03614"},{"issue":"10","key":"10.1016\/j.ejrad.2023.111263_b0030","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.annonc.2022.07.003","article-title":"Oesophageal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up","volume":"33","author":"Obermannov\u00e1","year":"2022","journal-title":"Ann Oncol off J Eur Soc Med Oncol."},{"issue":"9","key":"10.1016\/j.ejrad.2023.111263_b0035","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1007\/s00330-013-2844-8","article-title":"Accuracy of multidetector-row CT for restaging after neoadjuvant treatment in patients with oesophageal cancer","volume":"23","author":"Konieczny","year":"2013","journal-title":"Eur Radiol. Sept"},{"issue":"8","key":"10.1016\/j.ejrad.2023.111263_b0040","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1111\/dote.12274","article-title":"Staging accuracy of endoscopic ultrasound for esophageal cancer after neoadjuvant chemotherapy: a meta-analysis and systematic review","volume":"28","author":"Sun","year":"2015","journal-title":"Dis Esophagus off J Int Soc Dis Esophagus."},{"issue":"2","key":"10.1016\/j.ejrad.2023.111263_b0045","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/S0016-5107(98)70157-9","article-title":"Endoscopic ultrasound in restaging of esophageal cancer after neoadjuvant chemoradiation","volume":"48","author":"Isenberg","year":"1998","journal-title":"Gastrointest Endosc. Ao\u00fbt"},{"issue":"3","key":"10.1016\/j.ejrad.2023.111263_b0050","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1038\/sj.bjc.6604200","article-title":"Staging investigations for oesophageal cancer: a meta-analysis","volume":"98","author":"Van Vliet","year":"2008","journal-title":"Br J Cancer. F\u00e9vr"},{"issue":"2","key":"10.1016\/j.ejrad.2023.111263_b0055","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s00428-017-2232-x","article-title":"Tumor regression grading of gastrointestinal cancers after neoadjuvant therapy","volume":"472","author":"Langer","year":"2018","journal-title":"Virchows Arch Int J Pathol. F\u00e9vr"},{"key":"10.1016\/j.ejrad.2023.111263_b0060","doi-asserted-by":"crossref","unstructured":"Patel UB, Taylor F, Blomqvist L, George C, Evans H, Tekkis P, et al. Magnetic resonance imaging-detected tumor response for locally advanced rectal cancer predicts survival outcomes: MERCURY experience. J Clin Oncol Off J Am Soc Clin Oncol. 1 oct 2011;29(28):3753\u201360.","DOI":"10.1200\/JCO.2011.34.9068"},{"issue":"11","key":"10.1016\/j.ejrad.2023.111263_b0065","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1002\/bjs.11233","article-title":"Early MRI predictors of disease-free survival in locally advanced rectal cancer from the GRECCAR 4 trial","volume":"106","author":"Nougaret","year":"2019","journal-title":"Br J Surg."},{"issue":"9","key":"10.1016\/j.ejrad.2023.111263_b0070","first-page":"1065","article-title":"Prognostic Value of Tumor Regression Grade on MR in Rectal Cancer: A Large-Scale","volume":"21","author":"Yoen","year":"2020","journal-title":"Single-Center Experience. Korean J Radiol. Sept"},{"key":"10.1016\/j.ejrad.2023.111263_b0075","doi-asserted-by":"crossref","unstructured":"Glynne-Jones R, Wyrwicz L, Tiret E, Brown G, R\u00f6del C, Cervantes A, et al. Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol Off J Eur Soc Med Oncol. 1 oct 2018;29(Suppl 4):iv263.","DOI":"10.1093\/annonc\/mdy161"},{"issue":"2","key":"10.1016\/j.ejrad.2023.111263_b0080","first-page":"367","article-title":"MRI of Rectal Cancer: Tumor Staging","volume":"39","author":"Horvat","year":"2019","journal-title":"Imaging Techniques, and Management. Radiographics. Mars"},{"issue":"3","key":"10.1016\/j.ejrad.2023.111263_b0085","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1148\/radiol.2021202857","article-title":"Diagnostic Performance of MRI for Esophageal Carcinoma: A Systematic Review and Meta-Analysis","volume":"299","author":"Lee","year":"2021","journal-title":"Radiology. Juin"},{"issue":"8","key":"10.1016\/j.ejrad.2023.111263_b0090","doi-asserted-by":"crossref","first-page":"399","DOI":"10.5732\/cjc.011.10406","article-title":"The predictive value of histological tumor regression grading (TRG) for therapeutic evaluation in locally advanced esophageal carcinoma treated with neoadjuvant chemotherapy","volume":"31","author":"Guo","year":"2012","journal-title":"Chin J Cancer. Ao\u00fbt"},{"issue":"1","key":"10.1016\/j.ejrad.2023.111263_b0095","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.athoracsur.2011.05.021","article-title":"Does the Timing of Esophagectomy After Chemoradiation Affect Outcome?","volume":"93","author":"Kim","year":"2012","journal-title":"Ann Thorac Surg. Janv"},{"issue":"10","key":"10.1016\/j.ejrad.2023.111263_b0100","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1245\/s10434-008-9892-3","article-title":"An Interval >7 Weeks between Neoadjuvant Therapy and Surgery Improves Pathologic Complete Response and Disease-Free Survival in Patients with Locally Advanced Rectal Cancer","volume":"15","author":"Tulchinsky","year":"2008","journal-title":"Ann Surg Oncol."},{"key":"10.1016\/j.ejrad.2023.111263_b0105","doi-asserted-by":"crossref","unstructured":"Mandard AM, Dalibard F, Mandard JC, Marnay J, Henry-Amar M, Petiot JF, et al. Pathologic assessment of tumor regression after preoperative chemoradiotherapy of esophageal carcinoma. Clinicopathologic correlations. Cancer. 1 juin 1994;73(11):2680\u20136.","DOI":"10.1002\/1097-0142(19940601)73:11<2680::AID-CNCR2820731105>3.0.CO;2-C"},{"key":"10.1016\/j.ejrad.2023.111263_b0110","doi-asserted-by":"crossref","unstructured":"Becker K, Mueller JD, Schulmacher C, Ott K, Fink U, Busch R, et al. Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy. Cancer. 1 oct 2003;98(7):1521\u201330.","DOI":"10.1002\/cncr.11660"},{"issue":"7","key":"10.1016\/j.ejrad.2023.111263_b0115","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.3348\/kjr.2018.0611","article-title":"Response Assessment with MRI after Chemoradiotherapy in Rectal Cancer: Current Evidences","volume":"20","author":"Seo","year":"2019","journal-title":"Korean J Radiol. Juill"},{"issue":"1","key":"10.1016\/j.ejrad.2023.111263_b0120","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2307\/2529310","article-title":"The measurement of observer agreement for categorical data","volume":"33","author":"Landis","year":"1977","journal-title":"Biometrics. Mars"},{"issue":"3","key":"10.1016\/j.ejrad.2023.111263_b0125","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1159\/000351435","article-title":"Diffusion-Weighted Magnetic Resonance Imaging for Predicting and Detecting the Early Response to Chemoradiotherapy of Advanced Esophageal Squamous Cell Carcinoma","volume":"30","author":"Imanishi","year":"2013","journal-title":"Dig Surg."},{"issue":"4","key":"10.1016\/j.ejrad.2023.111263_b0130","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1159\/000328770","article-title":"Apparent Diffusion Coefficient Values Measured by Diffusion-Weighted Imaging Predict Chemoradiotherapeutic Effect for Advanced Esophageal Cancer","volume":"28","author":"Aoyagi","year":"2011","journal-title":"Dig Surg."},{"issue":"2","key":"10.1016\/j.ejrad.2023.111263_b0135","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.radonc.2015.04.027","article-title":"Diffusion-weighted magnetic resonance imaging for the prediction of pathologic response to neoadjuvant chemoradiotherapy in esophageal cancer","volume":"115","author":"van Rossum","year":"2015","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol. Mai"},{"key":"10.1016\/j.ejrad.2023.111263_b0140","article-title":"Evaluation of a multiparametric MRI scoring system for histopathologic treatment response following preoperative chemoradiotherapy for rectal cancer","volume":"138","author":"Khwaja","year":"2021","journal-title":"Eur J Radiol. Mai"},{"issue":"5","key":"10.1016\/j.ejrad.2023.111263_b0145","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.ijrobp.2019.12.038","article-title":"Preoperative Prediction of Pathologic Response to Neoadjuvant Chemoradiotherapy in Patients With Esophageal Cancer Using 18F-FDG PET\/CT and DW-MRI: A Prospective Multicenter Study","volume":"106","author":"Borggreve","year":"2020","journal-title":"Int J Radiat Oncol. Avr"},{"issue":"1","key":"10.1016\/j.ejrad.2023.111263_b0150","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1186\/s13014-021-01852-z","article-title":"Diffusion-weighted MRI and 18F-FDG PET\/CT in assessing the response to neoadjuvant chemoradiotherapy in locally advanced esophageal squamous cell carcinoma","volume":"16","author":"Xu","year":"2021","journal-title":"Radiat Oncol. D\u00e9c"},{"issue":"9","key":"10.1016\/j.ejrad.2023.111263_b0155","article-title":"Connection and distinction of tumor regression grading systems of gastrointestinal cancer","volume":"216","author":"Tong","year":"2020","journal-title":"Pathol - Res Pract. Sept"},{"key":"10.1016\/j.ejrad.2023.111263_b0160","doi-asserted-by":"crossref","unstructured":"Bott RK, Beckmann K, Zylstra J, Wilkinson MJ, Knight WRC, Baker CR, et al. Adjuvant therapy following neoadjuvant chemotherapy and surgery for oesophageal adenocarcinoma in patients with clear resection margins. Acta Oncol. 4 mai 2021;60(5):672\u201380.","DOI":"10.1080\/0284186X.2021.1885057"},{"issue":"5","key":"10.1016\/j.ejrad.2023.111263_b0165","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1097\/01.sla.0000254367.15810.38","article-title":"Long-term outcomes following neoadjuvant chemoradiotherapy for esophageal cancer","volume":"245","author":"Reynolds","year":"2007","journal-title":"Ann Surg. Mai"},{"issue":"8","key":"10.1016\/j.ejrad.2023.111263_b0170","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1177\/1066896919869477","article-title":"Pathological Tumor Regression Grade Classifications in Gastrointestinal Cancers: Role on Patients\u2019 Prognosis","volume":"27","author":"Fanelli","year":"2019","journal-title":"Int J Surg Pathol. D\u00e9c"},{"key":"10.1016\/j.ejrad.2023.111263_b0175","doi-asserted-by":"crossref","unstructured":"Hipp J, Nagavci B, Schmoor C, Meerpohl J, Hoeppner J, Schmucker C. Post-Neoadjuvant Surveillance and Surgery as Needed Compared with Post-Neoadjuvant Surgery on Principle in Multimodal Treatment for Esophageal Cancer: A Scoping Review. Cancers. 23 janv 2021;13(3):429.","DOI":"10.3390\/cancers13030429"},{"issue":"9","key":"10.1016\/j.ejrad.2023.111263_b0180","doi-asserted-by":"crossref","first-page":"5123","DOI":"10.21873\/anticanres.13707","article-title":"A Randomized Phase III Trial on the Role of Esophagectomy in Complete Responders to Preoperative Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (ESOPRESSO)","volume":"39","author":"Park","year":"2019","journal-title":"Anticancer Res. Sept"},{"key":"10.1016\/j.ejrad.2023.111263_b0185","doi-asserted-by":"crossref","unstructured":"Stahl M, Stuschke M, Lehmann N, Meyer HJ, Walz MK, Seeber S, et al. Chemoradiation With and Without Surgery in Patients With Locally Advanced Squamous Cell Carcinoma of the Esophagus. J Clin Oncol. 1 avr 2005;23(10):2310\u20137.","DOI":"10.1200\/JCO.2005.00.034"},{"issue":"6","key":"10.1016\/j.ejrad.2023.111263_b0190","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1097\/SLA.0000000000003636","article-title":"Active Surveillance Versus Immediate Surgery in Clinically Complete Responders After Neoadjuvant Chemoradiotherapy for Esophageal Cancer: A Multicenter Propensity Matched Study","volume":"274","author":"Van Der Wille","year":"2021","journal-title":"Ann Surg. D\u00e9c"},{"issue":"16","key":"10.1016\/j.ejrad.2023.111263_b0195","doi-asserted-by":"crossref","first-page":"5881","DOI":"10.1002\/cam4.3273","article-title":"Clinical response to chemoradiotherapy in esophageal carcinoma is associated with survival and benefit of consolidation chemotherapy","volume":"9","author":"Zhao","year":"2020","journal-title":"Cancer Med. Ao\u00fbt"},{"issue":"7","key":"10.1016\/j.ejrad.2023.111263_b0200","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/jso.24601","article-title":"The role of adjuvant platinum-based chemotherapy in esophagogastric cancer patients who received neoadjuvant chemotherapy prior to definitive surgery","volume":"115","author":"Saunders","year":"2017","journal-title":"J Surg Oncol. Juin"}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X23005776?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X23005776?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T11:44:16Z","timestamp":1733053456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X23005776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":40,"alternative-id":["S0720048X23005776"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2023.111263","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prospective evaluation of MR-TRG (Tumor Regression Grade) in esophageal cancer after neo-adjuvant therapy: Preliminary results","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2023.111263","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"111263"}}