{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T19:19:51Z","timestamp":1790968791435,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","ejradiology.com","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.ejrad.2024.111845","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T07:51:12Z","timestamp":1732607472000},"page":"111845","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Heterogeneous development of liver fibrosis in chronic hepatitis C patients; assessment by extracellular volume fraction map generated from routine clinical CT data"],"prefix":"10.1016","volume":"182","author":[{"given":"Eiko","family":"Hisatomi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinji","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nahoko","family":"Goto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Murayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisatomi","family":"Arima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihisa","family":"Takayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8530-2849","authenticated-orcid":false,"given":"Kengo","family":"Yoshimitsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2024.111845_b0005","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1148\/radiol.10100468","article-title":"Selective atrophy of the middle hepatic venous drainage area in hepatitis C-related cirrhotic liver: morphometric study by using multidetector CT","volume":"257","author":"Ozaki","year":"2010","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2024.111845_b0010","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20150896","article-title":"Morphometric changes in liver cirrhosis: aetiological differences correlated with progression","volume":"89","author":"Ozaki","year":"2016","journal-title":"BJR"},{"issue":"9","key":"10.1016\/j.ejrad.2024.111845_b0015","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/s11604-020-00978-6","article-title":"Morphometric changes and imaging findings of diffuse liver disease in relation to intrahepatic hemodynamics","volume":"38","author":"Ozaki","year":"2020","journal-title":"Jpn. J. Radiol."},{"key":"10.1016\/j.ejrad.2024.111845_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2021.110033","article-title":"Assessing the progression of segmental fibrosis in chronic liver disease using extracellular volume fractions","volume":"145","author":"Ozaki","year":"2021","journal-title":"EJR."},{"key":"10.1016\/j.ejrad.2024.111845_b0025","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1148\/radiology.211.3.r99ma31723","article-title":"Expanded gallbladder fossa: simple MR imaging sign of cirrhosis","volume":"211","author":"Ito","year":"1999","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2024.111845_b0030","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1002\/(SICI)1522-2586(200002)11:2<136::AID-JMRI9>3.0.CO;2-B","article-title":"Enlargement of hilar periportal space: a sign of early cirrhosis at MR imaging","volume":"11","author":"Ito","year":"2000","journal-title":"J. Magn. Reason Imaging"},{"key":"10.1016\/j.ejrad.2024.111845_b0035","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1148\/radiol.2243011495","article-title":"Cirrhosis: modified caudate-right lobe ratio","volume":"224","author":"Awaya","year":"2002","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2024.111845_b0040","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1002\/jmri.10387","article-title":"Right posterior hepatic notch sign: a simple diagnostic MRI finding of cirrhosis","volume":"18","author":"Ito","year":"2003","journal-title":"J. Magn. Reason Imaging"},{"key":"10.1016\/j.ejrad.2024.111845_b0045","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1159\/000078465","article-title":"Imaging diagnosis of cirrhosis and chronic hepatitis","volume":"47","author":"Ito","year":"2004","journal-title":"Intervirology"},{"issue":"4","key":"10.1016\/j.ejrad.2024.111845_b0050","first-page":"231","article-title":"ROmbouts K Liver fibrosis: from the bench to clinical targets, dig liver","volume":"36","author":"Pinzani","year":"2004","journal-title":"Dis."},{"key":"10.1016\/j.ejrad.2024.111845_b0055","unstructured":"QIBA profile: magnetic resonance elastography of the liver. https:\/\/qibawiki.rsna.org\/images\/6\/66\/MRE-QIBA_Profile-2021-06-22-CONSENSUS-maintenance.pdf Lastly accessed on Feb.7, 2022."},{"key":"10.1016\/j.ejrad.2024.111845_b0060","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.mric.2014.05.001","article-title":"Magnetic resonance elastography of liver","volume":"22","author":"Venkatesh","year":"2014","journal-title":"Magn. Reson Imaging Clin. N Am."},{"key":"10.1016\/j.ejrad.2024.111845_b0065","doi-asserted-by":"crossref","first-page":"22","DOI":"10.2214\/AJR.15.14552","article-title":"Ultrasound elastography and MR elastography of assessing liver fibrosis: part1 principles and techniques","author":"Tang","year":"2015","journal-title":"AJR"},{"key":"10.1016\/j.ejrad.2024.111845_b0070","doi-asserted-by":"crossref","first-page":"33","DOI":"10.2214\/AJR.15.14553","article-title":"Ultrasound elastography and MR elastography for assessing liver fibrosis: part2 diagnostic performance, confounders, and future directions","volume":"205","author":"Tang","year":"2015","journal-title":"AJR"},{"key":"10.1016\/j.ejrad.2024.111845_b0075","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1007\/s00330-015-3863-4","article-title":"MR elastography of the liver at 3.0 T in diagnosing liver fibrosis grades: preliminary clinical experience","volume":"26","author":"Yoshimitsu","year":"2016","journal-title":"Eur. Radiol."},{"key":"10.1016\/j.ejrad.2024.111845_b0080","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1148\/radiol.12112452","article-title":"Hepatic fibrosis: evaluation with semiquantitative contrast-enhanced CT","volume":"266","author":"Varenika","year":"2013","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2024.111845_b0085","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.2214\/AJR.12.10039","article-title":"Contrast-enhanced CT quantification of the hepatic fractional extracellular space: correlation with diffuse liver disease severity","volume":"201","author":"Zissen","year":"2013","journal-title":"AJR"},{"key":"10.1016\/j.ejrad.2024.111845_b0090","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1148\/radiol.14141435","article-title":"Equilibrium Contrast-enhanced CT imaging to evaluate hepatic fibrosis: initial validation by comparison with histopathologic analysis","volume":"275","author":"Bandula","year":"2015","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2024.111845_b0095","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1097\/RLI.0000000000000123","article-title":"Estimation of hepatic extracellular volume fraction using multiphasic liver computed tomography for hepatic fibrosis grading","volume":"50","author":"Yoon","year":"2015","journal-title":"Invest. Radiol."},{"key":"10.1016\/j.ejrad.2024.111845_b0100","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.ejrad.2018.04.012","article-title":"Usefulness of new subtraction algorithm in estimating degree of liver fibrosis by calculating extracellular volume fraction obtained from routine liver CT protocol equilibrium phase data: preliminary experience","volume":"103","author":"Shinagawa","year":"2018","journal-title":"EJR"},{"key":"10.1016\/j.ejrad.2024.111845_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2021.109924","article-title":"Importance of extracellular volume fraction of the spleen as a predictive biomarker for high-risk esophago-gastric varices in patients with chronic liver diseases: a preliminary report","volume":"143","author":"Tani","year":"2021","journal-title":"Eur. J. Radiol."},{"key":"10.1016\/j.ejrad.2024.111845_b0110","first-page":"365","article-title":"Usefulness of iodine-blood material density images in estimating degree of liver fibrosis by calculating extracellular volume fraction obtained from routine dual-energy liver CT protocol equilibrium phase data: preliminary experience","volume":"38","author":"Ito","year":"2020","journal-title":"JJR"},{"key":"10.1016\/j.ejrad.2024.111845_b0115","unstructured":"Centers for Disease Control and Prevention (CDC): MMWR Morb Mortal Wkly Rep. 2013;62(18):362-5, https:\/\/www.cdc.gov\/mmwr\/preview\/mmwrhtml\/mm6218a5.htm, lastly accessed on May 1, 2024."},{"key":"10.1016\/j.ejrad.2024.111845_b0120","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1159\/000488778","article-title":"Validation of modified ALBI grade for more detailed assessment of hepatic function in hepatocellular carcinoma patients: a multicenter analysis","volume":"8","author":"Hiraoka","year":"2019","journal-title":"Liver Cancer."},{"key":"10.1016\/j.ejrad.2024.111845_b0125","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1148\/radiol.2411051102","article-title":"Atrophy-hypertrophy complex in patients with cavernous transformation of the portal vein: CT evaluation","volume":"241","author":"Vilgrain","year":"2006","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2024.111845_b0130","first-page":"179","article-title":"Pathomorphologic comparison of hepatitis C virus-related and hepatitis B virus-related cirrhosis bearing hepatocellular carcinoma","volume":"25","author":"Kojiro","year":"1995","journal-title":"Princess Takamatsu Symp."},{"key":"10.1016\/j.ejrad.2024.111845_b0135","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jvir.2017.12.002","article-title":"Isolated arteries originating from the intrahepatic arteries: anatomy, function, and importance in intervention","volume":"29","author":"Yoshida","year":"2018","journal-title":"JVIR"},{"key":"10.1016\/j.ejrad.2024.111845_b0140","doi-asserted-by":"crossref","DOI":"10.35772\/ghm.2023.01085","article-title":"Gallbladder fossa nodularity in the liver as observed in alcoholic liver disease patients: analysis based on hepatobiliary phase signal intensity on gadoxetate-enhanced MRI and extracellular volume fraction calculated from routine CT data","author":"Sato","year":"2024","journal-title":"Global Health & Medicine"},{"key":"10.1016\/j.ejrad.2024.111845_b0145","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1177\/2050640618791053","article-title":"Short-term histological evaluations after achieving a sustained virologic response to direct-acting antiviral treatment for chronic hepatitis C","volume":"6","author":"Enomoto","year":"2018","journal-title":"United European Gastroenterol. J."}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X24005618?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X24005618?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T16:37:04Z","timestamp":1734021424000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X24005618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":29,"alternative-id":["S0720048X24005618"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2024.111845","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Heterogeneous development of liver fibrosis in chronic hepatitis C patients; assessment by extracellular volume fraction map generated from routine clinical CT data","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2024.111845","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111845"}}