{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T04:22:07Z","timestamp":1745986927751,"version":"3.40.4"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","ejradiology.com","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.ejrad.2025.111924","type":"journal-article","created":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:36:21Z","timestamp":1736555781000},"page":"111924","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["The added value of b0-DWI analysis in the diagnosis of cavitating lacunes when T2-weighted spin-echo is unavailable"],"prefix":"10.1016","volume":"183","author":[{"given":"C\u00e9line","family":"Leung Kune Chong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreea","family":"Aignatoaie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Salem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Canan","family":"Ozsancak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Magni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gr\u00e9goire","family":"Boulouis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9lo\u00efse","family":"Ifergan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Philippe","family":"Cottier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Pasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Auzou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilles","family":"Metrard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8200-2784","authenticated-orcid":false,"given":"Clara","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2025.111924_b0005","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S1474-4422(13)70124-8","article-title":"Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration","volume":"12","author":"Wardlaw","year":"2013","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.ejrad.2025.111924_b0010","doi-asserted-by":"crossref","first-page":"365","DOI":"10.6061\/clinics\/2013(03)OA13","article-title":"The 'silence\u2019 of silent brain infarctions may be related to chronic ischemic preconditioning and nonstrategic locations rather than to a small infarction size","volume":"68","author":"Feng","year":"2013","journal-title":"Clinics"},{"key":"10.1016\/j.ejrad.2025.111924_b0015","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1161\/STROKEAHA.112.660076","article-title":"Cavitation of deep lacunar infarcts in patients with first-ever lacunar stroke: a 2-year follow-up study with MR","volume":"43","author":"Loos","year":"2012","journal-title":"Stroke"},{"key":"10.1016\/j.ejrad.2025.111924_b0020","first-page":"3705","article-title":"Cavitation of symptomatic acute single small subcortical infarctions","volume":"41","author":"Zhang","year":"2020","journal-title":"Neurol. Sci. Off. J. Ital. Neurol. Soc. Ital. Soc. Clin. Neurophysiol."},{"key":"10.1016\/j.ejrad.2025.111924_b0025","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/S1474-4422(23)00131-X","article-title":"Neuroimaging standards for research into small vessel disease\u2014advances since 2013","volume":"22","author":"Duering","year":"2023","journal-title":"Lancet Neurol."},{"doi-asserted-by":"crossref","unstructured":"J.M. Wardlaw, H. Benveniste, M. Nedergaard, B.V. Zlokovic, H. Mestre, H. Lee, F.N. Doubal, R. Brown, J. Ramirez, B.J. MacIntosh, A. Tannenbaum, L. Ballerini, R.L. Rungta, D. Boido, M. Sweeney, A. Montagne, S. Charpak, A. Joutel, K.J. Smith, S.E. Black, colleagues from the Fondation Leducq Transatlantic Network of Excellence on the Role of the Perivascular Space in Cerebral Small Vessel Disease, Perivascular spaces in the brain: anatomy, physiology and pathology, Nat. Rev. Neurol. 16 (2020) 137\u2013153. doi: 10.1038\/s41582-020-0312-z.","key":"10.1016\/j.ejrad.2025.111924_b0030","DOI":"10.1038\/s41582-020-0312-z"},{"key":"10.1016\/j.ejrad.2025.111924_b0035","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.neurol.2017.03.005","article-title":"Diffusion magnetic resonance imaging in cerebral small vessel disease","volume":"173","author":"Lyoubi-Idrissi","year":"2017","journal-title":"Rev. Neurol. (Paris)"},{"key":"10.1016\/j.ejrad.2025.111924_b0040","doi-asserted-by":"crossref","first-page":"33","DOI":"10.5334\/jbsr.2352","article-title":"MRI in early onset of Creutzfeldt Jakob disease","volume":"105","author":"Lorent","year":"2021","journal-title":"J. Belg. Soc. Radiol."},{"doi-asserted-by":"crossref","unstructured":"PICASSO investigators, H.S. Kwon, A.-H. Cho, M.H. Lee, D. Lee, D.-E. Jeong, C. Choi, J. Jang, S. Yu, J.-H. Park, S.H. Heo, J.-S. Lee, S.U. Kwon, Evolution of acute lacunar lesions in terms of size and shape: a PICASSO sub-study, J. Neurol. 266 (2019) 766\u2013772. doi: 10.1007\/s00415-019-09201-7.","key":"10.1016\/j.ejrad.2025.111924_b0045","DOI":"10.1007\/s00415-019-09201-7"},{"key":"10.1016\/j.ejrad.2025.111924_b0050","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1161\/STROKEAHA.111.647859","article-title":"Cavitation after acute symptomatic lacunar stroke depends on time, location, and MRI sequence","volume":"43","author":"Moreau","year":"2012","journal-title":"Stroke"},{"doi-asserted-by":"crossref","unstructured":"S.P.R. Luijten, N.A.M. van der Ende, S.A.P. Cornelissen, L. Kluijtmans, A. van Hattem, G. Lycklama A Nijeholt, A.A. Postma, R.P.H. Bokkers, L. Thomassen, U. Waje-Andreassen, N. Logallo, S. Bracard, B. Gory, B. Roozenbeek, D.W.J. Dippel, A. van der Lugt, Comparison of diffusion weighted imaging b0 with T2*-weighted gradient echo or susceptibility weighted imaging for intracranial hemorrhage detection after reperfusion therapy for ischemic stroke, Neuroradiology 65 (2023) 1649\u20131655. doi: 10.1007\/s00234-023-03180-3.","key":"10.1016\/j.ejrad.2025.111924_b0055","DOI":"10.1007\/s00234-023-03180-3"},{"key":"10.1016\/j.ejrad.2025.111924_b0060","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.neurad.2023.12.001","article-title":"Energy consumption in MRI: determinants and management options","volume":"51","author":"Chodorowski","year":"2024","journal-title":"J. Neuroradiol."},{"key":"10.1016\/j.ejrad.2025.111924_b0065","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-012799","article-title":"STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration","volume":"6","author":"Cohen","year":"2016","journal-title":"BMJ Open"},{"key":"10.1016\/j.ejrad.2025.111924_b0070","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.1161\/STROKEAHA.120.030686","article-title":"Covert brain infarction: towards precision medicine in research, diagnosis, and therapy for a silent pandemic","volume":"51","author":"Meinel","year":"2020","journal-title":"Stroke"},{"key":"10.1016\/j.ejrad.2025.111924_b0075","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1161\/STROKEAHA.121.034347","article-title":"Phenotypes of chronic covert brain infarction in patients with first-ever ischemic stroke: a cohort study","volume":"53","author":"Vynckier","year":"2022","journal-title":"Stroke"},{"key":"10.1016\/j.ejrad.2025.111924_b0080","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1161\/01.STR.32.6.1318","article-title":"A new rating scale for age-related white matter changes applicable to MRI and CT","volume":"32","author":"Wahlund","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.ejrad.2025.111924_b0085","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1007\/s12975-019-00741-8","article-title":"Predictors of lesion cavitation after recent small subcortical stroke","volume":"11","author":"Gattringer","year":"2020","journal-title":"Transl. Stroke Res."},{"key":"10.1016\/j.ejrad.2025.111924_b0090","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1161\/STROKEAHA.115.011889","article-title":"Silent brain infarction and risk of future stroke: a systematic review and meta-analysis","volume":"47","author":"Gupta","year":"2016","journal-title":"Stroke"},{"key":"10.1016\/j.ejrad.2025.111924_b0095","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1177\/23969873231187444","article-title":"Management of covert brain infarction survey: a call to care for and trial this neglected population","volume":"8","author":"Meinel","year":"2023","journal-title":"Eur. Stroke J."},{"key":"10.1016\/j.ejrad.2025.111924_b0100","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1161\/STROKEAHA.115.011501","article-title":"Does b1000\u2013b0 mismatch challenge diffusion-weighted imaging\u2013fluid attenuated inversion recovery mismatch in stroke?","volume":"47","author":"Geraldo","year":"2016","journal-title":"Stroke"},{"key":"10.1016\/j.ejrad.2025.111924_b0105","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1148\/radiol.211394","article-title":"Synthetic FLAIR as a substitute for FLAIR sequence in acute ischemic stroke","volume":"303","author":"Benzakoun","year":"2022","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2025.111924_b0110","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1177\/17474930221091879","article-title":"Advanced MRI in cerebral small vessel disease","volume":"18","author":"Van Den Brink","year":"2023","journal-title":"Int. J. Stroke"},{"key":"10.1016\/j.ejrad.2025.111924_b0115","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.clinimag.2018.05.017","article-title":"Comparing lesion detection of infratentorial multiple sclerosis lesions between T2-weighted spin-echo, 2D-FLAIR, and 3D-FLAIR sequences","volume":"51","author":"Wang","year":"2018","journal-title":"Clin. Imaging"},{"key":"10.1016\/j.ejrad.2025.111924_b0120","doi-asserted-by":"crossref","DOI":"10.1177\/23969873211012132","article-title":"ESO Guideline on covert cerebral small vessel disease","volume":"6","author":"Wardlaw","year":"2021","journal-title":"Eur. Stroke J."},{"key":"10.1016\/j.ejrad.2025.111924_b0125","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1161\/STROKEAHA.119.024150","article-title":"New treatment approaches to modify the course of cerebral small vessel diseases","volume":"51","author":"Smith","year":"2020","journal-title":"Stroke"},{"key":"10.1016\/j.ejrad.2025.111924_b0130","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1161\/STROKEAHA.123.045664","article-title":"Effect of the blood pressure and antihypertensive drugs on cerebral small vessel disease: a Mendelian randomization study","volume":"55","author":"Ma","year":"2024","journal-title":"Stroke"},{"key":"10.1016\/j.ejrad.2025.111924_b0135","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1177\/17474930221144911","article-title":"Cerebral small vessel disease: recent advances and future directions","volume":"18","author":"Markus","year":"2023","journal-title":"Int. J. Stroke"},{"doi-asserted-by":"crossref","unstructured":"J.M. Wardlaw, L.J. Woodhouse, I.I. Mhlanga, K. Oatey, A.K. Heye, J. Bamford, V. Cvoro, F.N. Doubal, T. England, A. Hassan, A. Montgomery, J.T. O\u2019Brien, C. Roffe, N. Sprigg, D.J. Werring, P.M. Bath, Lacunar Intervention Trial-2 (LACI-2) Investigator Group, C. Baigent, G. Ford, J. Emberson, A. Murray, A.R. Naylor, K. Krishnan, J. Dawson, C. Patterson, G. Guzman Gutierrez, S. Makin, U. Khan, L. Sztriha, T. Booth, A. Kirthivasan, A. Ijaz, K. Harkness, S. Ispoglou, N. Smyth, A. Sivagnanaratnam, D. Cohen, L. Sekaran, D. Chadha, N. Ahmad, P. Rana, M. Hussain, N. Weir, T. Harrison, S. Elyas, Isosorbide Mononitrate and Cilostazol Treatment in Patients With Symptomatic Cerebral Small Vessel Disease: The Lacunar Intervention Trial-2 (LACI-2) Randomized Clinical Trial, JAMA Neurol. 80 (2023) 682. doi: 10.1001\/jamaneurol.2023.1526.","key":"10.1016\/j.ejrad.2025.111924_b0140","DOI":"10.1001\/jamaneurol.2023.1526"},{"key":"10.1016\/j.ejrad.2025.111924_b0145","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1159\/000508732","article-title":"Lacune and large perivascular space: two kinds of cavities are of different risk factors and stroke risk","volume":"49","author":"Zhang","year":"2020","journal-title":"Cerebrovasc. Dis."}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X25000105?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X25000105?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T20:01:20Z","timestamp":1745956880000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X25000105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":29,"alternative-id":["S0720048X25000105"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2025.111924","relation":{},"ISSN":["0720-048X"],"issn-type":[{"type":"print","value":"0720-048X"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The added value of b0-DWI analysis in the diagnosis of cavitating lacunes when T2-weighted spin-echo is unavailable","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2025.111924","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"111924"}}