{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:24:46Z","timestamp":1785795886475,"version":"3.56.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejradiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.ejrad.2025.112164","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T23:16:13Z","timestamp":1746832573000},"page":"112164","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Brain pulsation demonstrated by CSF flow artifacts on FLAIR images might be associated with brain function"],"prefix":"10.1016","volume":"189","author":[{"given":"Toshio","family":"Imaizumi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoya","family":"Sakashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riku","family":"Ohwada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoichi","family":"Komura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoaki","family":"Tamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ejrad.2025.112164_b0005","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202000895","article-title":"Biomaterial based strategies for engineering new lymphatic vasculature","volume":"9","author":"Campbell","year":"2020","journal-title":"Adv. Healthcare Mater."},{"key":"10.1016\/j.ejrad.2025.112164_b0010","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1161\/ATVBAHA.119.312396","article-title":"Cardiac lymphatic dysfunction causes drug-eluting stent-induced coronary hyperconstricting responses in pigs in vivo","volume":"39","author":"Amamizu","year":"2019","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ejrad.2025.112164_b0015","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/S1474-4422(18)30318-1","article-title":"The glymphatic pathway in neurological disorders","volume":"17","author":"Rasmussen","year":"2018","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.ejrad.2025.112164_b0020","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nrneurol.2015.119","article-title":"Clearance systems in the brain-implications for Alzheimer disease","volume":"11","author":"Tarasoff-Conway","year":"2015","journal-title":"Nat. Rev. Neurol."},{"key":"10.1016\/j.ejrad.2025.112164_b0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2022.119362","article-title":"Cerebrovascular activity is a major factor in the cerebrospinal fluid flow dynamics","volume":"258","author":"Wang","year":"2022","journal-title":"Neuroimage"},{"key":"10.1016\/j.ejrad.2025.112164_b0030","doi-asserted-by":"crossref","first-page":"18190","DOI":"10.1523\/JNEUROSCI.1592-13.2013","article-title":"Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brain","volume":"33","author":"Iliff","year":"2013","journal-title":"Neuroscience"},{"key":"10.1016\/j.ejrad.2025.112164_b0035","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1177\/0271678X17737984","article-title":"Paravascular spaces at the brain surface: Low resistance pathways for cerebrospinal fluid flow","volume":"38","author":"Bedussi","year":"2018","journal-title":"J. Cerebral Blood Flow Metab."},{"key":"10.1016\/j.ejrad.2025.112164_b0040","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1007\/s12031-020-01752-z","article-title":"L-3-n-butylphthalide effectively improves the glymphatic clearance and reduce amyloid-\u03b2 deposition in Alzheimer\u2019s transgenic mice","volume":"71","author":"Zhang","year":"2021","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.ejrad.2025.112164_b0045","article-title":"Impaired glymphatic function and pulsation alterations in a mouse model of vascular cognitive impairment","volume":"13","author":"Li","year":"2021","journal-title":"Front. Aging Neurosci."},{"issue":"9","key":"10.1016\/j.ejrad.2025.112164_b0050","doi-asserted-by":"crossref","first-page":"4878","DOI":"10.1038\/s41467-018-07318-3","article-title":"Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension","volume":"19","author":"Mestre","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ejrad.2025.112164_b0055","doi-asserted-by":"crossref","first-page":"10102","DOI":"10.1038\/s41598-020-66887-w","article-title":"Arterial pulsations drive oscillatory flow of CSF but not directional pumping","volume":"10","author":"Kedarasetti","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ejrad.2025.112164_b0060","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.brainres.2009.07.078","article-title":"Chronic cerebral hypoperfusion accelerates amyloid beta deposition in APPSwInd transgenic mice","volume":"1294","author":"Kitaguchi","year":"2009","journal-title":"Brain Res."},{"key":"10.1016\/j.ejrad.2025.112164_b0065","doi-asserted-by":"crossref","first-page":"311","DOI":"10.2174\/1567202620666221024123117","article-title":"CSF flow artifacts are associated with brain pulsation in patients with severe carotid artery stenoses","volume":"19","author":"Imaizumi","year":"2022","journal-title":"Curr. Neurovasc. Res."},{"key":"10.1016\/j.ejrad.2025.112164_b0070","doi-asserted-by":"crossref","first-page":"58","DOI":"10.7887\/jcns.33.58","article-title":"Moyamoya disease with changed cerebrospinal fluid flow artifact on fluid attenuated inversion recovery image after revascularization: A case report","volume":"33","author":"Suzuki","year":"2024","journal-title":"Japan. J. Neurosurg."},{"key":"10.1016\/j.ejrad.2025.112164_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2022.119293","article-title":"Measurement ofCSFpulsation from EPI-based human fMRI","volume":"257","author":"Kim","year":"2022","journal-title":"Neuroimage"},{"key":"10.1016\/j.ejrad.2025.112164_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2022.118888","article-title":"Autonomic arousals contribute to brain fluid pulsations during sleep","volume":"249","author":"Picchioni","year":"2022","journal-title":"Neuroimage"},{"key":"10.1016\/j.ejrad.2025.112164_b0085","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.2967\/jnumed.116.187211","article-title":"Cerebrospinal fluid clearance in Alzheimer disease measured with dynamic PET","volume":"58","author":"de Leon","year":"2017","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.ejrad.2025.112164_b0090","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/jnc.14283","article-title":"Cerebrovascular and Alzheimer disease: fellow travelers or partners in crime?","volume":"144","author":"Nucera","year":"2018","journal-title":"J. Neurochem."},{"key":"10.1016\/j.ejrad.2025.112164_b0095","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2214\/ajr.149.2.351","article-title":"MR signal abnormalities at 1.5 T in Alzheimer\u2019s dementia and normal aging","volume":"149","author":"Fazekas","year":"1987","journal-title":"Am. J. Roentgenol."},{"key":"10.1016\/j.ejrad.2025.112164_b0100","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1212\/WNL.0b013e3181c34a7d","article-title":"The microbleed anatomical rating scale (MARS): reliability of a tool to map brain microbleeds","volume":"73","author":"Gregoire","year":"2009","journal-title":"Neurology"},{"key":"10.1016\/j.ejrad.2025.112164_b0105","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.2337\/diacare.20.7.1183","article-title":"Report of the expert committee on the diagnostic classification of diabetes","volume":"20","author":"National Diabetes Data Group","year":"1997","journal-title":"Diabetes Care"},{"key":"10.1016\/j.ejrad.2025.112164_b0110","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1093\/cercor\/bhaa283","article-title":"Neurofunctional components of simple calculation: A magnetoencephalography study","volume":"31","author":"Salillas","year":"2021","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.ejrad.2025.112164_b0115","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.ejrad.2017.07.013","article-title":"The Evans' index revisited. New cut-off levels for use in radiological assessment of ventricular enlargement in the elderly","volume":"95","author":"Brix","year":"2017","journal-title":"Eur. J. Radiol."},{"key":"10.1016\/j.ejrad.2025.112164_b0120","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2218782120","article-title":"Country-level gender inequality is associated with structural differences in the brains of omen and men","volume":"120","author":"Zugman","year":"2023","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ejrad.2025.112164_b0125","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1056\/NEJM199811123392002","article-title":"Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators","volume":"339","author":"Barnett","year":"1998","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ejrad.2025.112164_b0130","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1126\/science.1241224","article-title":"Sleep drives metabolite clearance from the adult brain","volume":"342","author":"Xie","year":"2013","journal-title":"Science"}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X25002505?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X25002505?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T18:56:47Z","timestamp":1749322607000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X25002505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":26,"alternative-id":["S0720048X25002505"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2025.112164","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Brain pulsation demonstrated by CSF flow artifacts on FLAIR images might be associated with brain function","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2025.112164","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112164"}}