{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:04:52Z","timestamp":1790233492034,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100020756","name":"Sichuan University West China Hospital of Stomatology","doi-asserted-by":"publisher","award":["LCYJ-QN-202512"],"award-info":[{"award-number":["LCYJ-QN-202512"]}],"id":[{"id":"10.13039\/100020756","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejradiology.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.ejrad.2026.113126","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T15:43:25Z","timestamp":1785944605000},"page":"113126","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Characterization of parotid lesions with dual-energy CT: Can virtual unenhanced images permit selective omission of true unenhanced acquisition?"],"prefix":"10.1016","volume":"204","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5709-0949","authenticated-orcid":false,"given":"Hongying","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyang","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranhui","family":"Xi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"You","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ejrad.2026.113126_b0005","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1148\/radiol.2015142631","article-title":"Dual- and multi-energy CT: principles, technical approaches, and clinical applications","volume":"276","author":"McCollough","year":"2015","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2026.113126_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcrc.2026.155589","article-title":"Dual-energy and photon-counting computed tomography in critical care","volume":"94","author":"Freed","year":"2026","journal-title":"J. Crit. Care"},{"issue":"3","key":"10.1016\/j.ejrad.2026.113126_b0015","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1148\/radiol.2021192448","article-title":"Virtual unenhanced dual-energy CT images obtained with a multimaterial decomposition algorithm: diagnostic value for renal mass and urinary stone evaluation","volume":"298","author":"Xiao","year":"2021","journal-title":"Radiology"},{"issue":"8","key":"10.1016\/j.ejrad.2026.113126_b0020","doi-asserted-by":"crossref","first-page":"2596","DOI":"10.1007\/s00261-023-03914-0","article-title":"Dual-energy CT of the pancreas: comparison between virtual non-contrast images and true non-contrast images in the detection of pancreatic lesion","volume":"48","author":"Liang","year":"2023","journal-title":"Abdom. Radiol. (NY)"},{"issue":"6","key":"10.1016\/j.ejrad.2026.113126_b0025","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.2214\/AJR.19.21299","article-title":"Dual-source dual-energy CT in submandibular sialolithiasis: reliability and radiation burden","volume":"213","author":"Pulickal","year":"2019","journal-title":"AJR Am. J. Roentgenol."},{"issue":"4","key":"10.1016\/j.ejrad.2026.113126_b0030","first-page":"711","article-title":"Feasibility study of using virtual non-contrast images derived from dual-energy CT to replace true non-contrast images in patients diagnosed with papillary thyroid carcinoma","volume":"29","author":"Zhou","year":"2021","journal-title":"J. Xray Sci. Technol."},{"issue":"3","key":"10.1016\/j.ejrad.2026.113126_b0035","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.ejrad.2008.01.027","article-title":"Imaging of salivary gland tumours","volume":"66","author":"Lee","year":"2008","journal-title":"Eur. J. Radiol."},{"issue":"10","key":"10.1016\/j.ejrad.2026.113126_b0040","doi-asserted-by":"crossref","first-page":"6801","DOI":"10.21037\/qims-23-467","article-title":"The evolution and current situation in the application of dual-energy computed tomography: a bibliometric study","volume":"13","author":"Wang","year":"2023","journal-title":"Quant. Imaging Med. Surg."},{"issue":"5","key":"10.1016\/j.ejrad.2026.113126_b0045","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1016\/j.acra.2023.08.024","article-title":"Evaluation of quantitative dual-energy computed tomography parameters for differentiation of parotid gland tumors","volume":"31","author":"Wang","year":"2024","journal-title":"Acad. Radiol."},{"key":"10.1016\/j.ejrad.2026.113126_b0050","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2025.1505385","article-title":"Nomogram combining dual-energy computed tomography features and radiomics for differentiating parotid warthin tumor from pleomorphic adenoma: a retrospective study","volume":"15","author":"Gong","year":"2025","journal-title":"Front. Oncol."},{"issue":"7","key":"10.1016\/j.ejrad.2026.113126_b0055","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1093\/dmfr\/twaf059","article-title":"Diagnostic performance of quantitative parameters derived from twin-beam dual-energy CT for differentiating benign and malignant salivary gland tumors of the palate","volume":"54","author":"Jo","year":"2025","journal-title":"Dentomaxillofac. Radiol."},{"issue":"4","key":"10.1016\/j.ejrad.2026.113126_b0060","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1148\/rg.2016150220","article-title":"Material separation using dual-energy CT: current and emerging applications","volume":"36","author":"Patino","year":"2016","journal-title":"Radiographics"},{"issue":"3","key":"10.1016\/j.ejrad.2026.113126_b0065","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1007\/s00261-016-0991-5","article-title":"Comparison of true unenhanced and virtual unenhanced (VUE) attenuation values in abdominopelvic single-source rapid kilovoltage-switching spectral CT","volume":"42","author":"Borhani","year":"2017","journal-title":"Abdom Radiol (NY)"},{"issue":"1","key":"10.1016\/j.ejrad.2026.113126_b0070","doi-asserted-by":"crossref","first-page":"81.e21","DOI":"10.1016\/j.crad.2020.08.026","article-title":"Replacing true unenhanced imaging in renal carcinoma with virtual unenhanced images in dual-energy spectral CT: a feasibility study","volume":"76","author":"Ma","year":"2021","journal-title":"Clin. Radiol."},{"issue":"5","key":"10.1016\/j.ejrad.2026.113126_b0075","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.2214\/AJR.11.7711","article-title":"Dual-source dual-energy CT evaluation of complex cystic renal masses","volume":"199","author":"Ascenti","year":"2012","journal-title":"AJR Am. J. Roentgenol."},{"issue":"11","key":"10.1016\/j.ejrad.2026.113126_b0080","doi-asserted-by":"crossref","first-page":"11512","DOI":"10.21037\/qims-2024-2524","article-title":"Dual-layer spectral detector computed tomography-derived virtual non-contrast images in breast cancer patients: a promising alternative to true non-contrast images","volume":"15","author":"Chen","year":"2025","journal-title":"Quant. Imaging Med. Surg."},{"issue":"5","key":"10.1016\/j.ejrad.2026.113126_b0085","doi-asserted-by":"crossref","first-page":"3950","DOI":"10.1007\/s00330-025-12191-y","article-title":"Replacing true non-contrast imaging with DECT in GI bleeding demonstrates non-inferior diagnostic performance, reading time and confidence","volume":"36","author":"Oberparleiter","year":"2026","journal-title":"Eur. Radiol."},{"issue":"8","key":"10.1016\/j.ejrad.2026.113126_b0090","article-title":"Can virtual non-contrast imaging replace true non-contrast imaging in multiphase scanning of the neck region?","volume":"12","author":"Al-Difaie","year":"2023","journal-title":"Acta Radiol. Open"},{"issue":"10","key":"10.1016\/j.ejrad.2026.113126_b0095","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1016\/j.ejrad.2014.06.017","article-title":"Incidental adrenal lesions detected on enhanced abdominal dual-energy CT: can the diagnostic workup be shortened by the implementation of virtual unenhanced images?","volume":"83","author":"Botsikas","year":"2014","journal-title":"Eur. J. Radiol."},{"issue":"9","key":"10.1016\/j.ejrad.2026.113126_b0100","doi-asserted-by":"crossref","first-page":"4345","DOI":"10.1007\/s00261-021-03062-3","article-title":"Dual-layer dual-energy CT for characterization of adrenal nodules: can virtual unenhanced images replace true unenhanced acquisitions?","volume":"46","author":"Cao","year":"2021","journal-title":"Abdom. Radiol. (NY)"},{"key":"10.1016\/j.ejrad.2026.113126_b0105","doi-asserted-by":"crossref","unstructured":"P. Bernard, C. Nelles, P. Fervers, J. Schwan, K. Dankov, D. Maintz, D. Zopfs, N. Gro\u00dfe Hokamp, T. Persigehl, S. Lennartz, Adrenal lesion classification revisited: validation and adjustment of dual-energy CT derived virtual unenhanced attenuation thresholds, Abdom Radiol (NY) 50(11) (2025) 5283-5291. Doi: 10.1007\/s00261-025-04939-3.","DOI":"10.1007\/s00261-025-04939-3"},{"key":"10.1016\/j.ejrad.2026.113126_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2024.111328","article-title":"Detection of moderate hepatic steatosis on contrast-enhanced dual-source dual-energy CT: Role and accuracy of virtual non-contrast CT","volume":"172","author":"Catania","year":"2024","journal-title":"Eur. J. Radiol."},{"issue":"6","key":"10.1016\/j.ejrad.2026.113126_b0115","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1007\/s00261-022-03482-9","article-title":"Detection of fatty liver using virtual non-contrast dual-energy CT","volume":"47","author":"Zhang","year":"2022","journal-title":"Abdom. Radiol. (NY)"},{"issue":"6","key":"10.1016\/j.ejrad.2026.113126_b0120","doi-asserted-by":"crossref","first-page":"594.e7","DOI":"10.1016\/j.crad.2018.01.018","article-title":"Single-energy non-contrast hepatic steatosis criteria applied to virtual non-contrast images: is it still highly specific and positively predictive?","volume":"73","author":"Haji-Momenian","year":"2018","journal-title":"Clin. Radiol."},{"issue":"1","key":"10.1016\/j.ejrad.2026.113126_b0125","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s00261-016-0842-4","article-title":"Comparison of virtual unenhanced CT images of the abdomen under different iodine flow rates","volume":"42","author":"Li","year":"2017","journal-title":"Abdom Radiol (NY)"},{"issue":"9","key":"10.1016\/j.ejrad.2026.113126_b0130","article-title":"Obesity-related pitfalls of virtual versus true non-contrast imaging-an intraindividual comparison in 253 oncologic patients","volume":"13","author":"Huflage","year":"2023","journal-title":"Diagnostics (basel)"},{"issue":"1","key":"10.1016\/j.ejrad.2026.113126_b0135","doi-asserted-by":"crossref","first-page":"986","DOI":"10.21037\/qims-23-1092","article-title":"Experimental study on the effects of different exposure conditions and contrast agent concentrations on spectral computed tomography virtual non-contrast images","volume":"14","author":"Zhao","year":"2024","journal-title":"Quant. Imaging Med. Surg."},{"key":"10.1016\/j.ejrad.2026.113126_b0140","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/8874100","article-title":"The clinical characteristics and CT findings of parotid and submandibular gland tumours","volume":"2021","author":"Zuo","year":"2021","journal-title":"J. Oncol."},{"issue":"20","key":"10.1016\/j.ejrad.2026.113126_b0145","doi-asserted-by":"crossref","first-page":"6487","DOI":"10.3390\/jcm12206487","article-title":"Three signs to help detect Sj\u00f6gren\u2019s syndrome: incidental findings on magnetic resonance imaging and computed tomography","volume":"12","author":"Takagi","year":"2023","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.ejrad.2026.113126_b0150","doi-asserted-by":"crossref","unstructured":"M. Bonatti, F. Lombardo, G.A. Zamboni, P. Pernter, R. Pozzi Mucelli, G. Bonatti, Dual-energy CT of the brain: Comparison between DECT angiography-derived virtual unenhanced images and true unenhanced images in the detection of intracranial haemorrhage, Eur Radiol 27(7) (2017) 2690-2697. Doi: 10.1007\/s00330-016-4658-y.","DOI":"10.1007\/s00330-016-4658-y"},{"issue":"11","key":"10.1016\/j.ejrad.2026.113126_b0155","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1007\/s00234-016-1736-4","article-title":"Detection of parathyroid adenomas using a monophasic dual-energy computed tomography acquisition: diagnostic performance and potential radiation dose reduction","volume":"58","author":"Leiva-Salinas","year":"2016","journal-title":"Neuroradiology"},{"issue":"4","key":"10.1016\/j.ejrad.2026.113126_b0160","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1053\/j.sult.2022.03.004","article-title":"Virtual non-contrast imaging in the abdomen and the pelvis: an overview","volume":"43","author":"Virarkar","year":"2022","journal-title":"Semin. Ultrasound CT MR"},{"issue":"14","key":"10.1016\/j.ejrad.2026.113126_b0165","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12144718","article-title":"Virtual non-contrast spectral CT in renal masses: is it time to discard conventional unenhanced phase?","volume":"12","author":"Bucolo","year":"2023","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.ejrad.2026.113126_b0170","doi-asserted-by":"crossref","unstructured":"United Nations Scientific Committee on the Effects of Atomic Radiation, Sources and Effects of Ionizing Radiation: UNSCEAR 2008 Report to the General Assembly, with Scientific Annexes. Volume I: Sources, United Nations, New York, 2010. https:\/\/www.unscear.org\/unscear\/en\/publications\/2008_1.html.","DOI":"10.18356\/9b8f628f-en"},{"issue":"1","key":"10.1016\/j.ejrad.2026.113126_b0175","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1148\/radiol.2481071451","article-title":"Effective doses in radiology and diagnostic nuclear medicine: a catalog","volume":"248","author":"Mettler","year":"2008","journal-title":"Radiology"},{"key":"10.1016\/j.ejrad.2026.113126_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2023.111031","article-title":"Dedicated virtual non-contrast images adapted for liver tissue in clinical photon counting CT improve virtual non-contrast imaging in various organs beyond the liver","volume":"167","author":"Schoenbeck","year":"2023","journal-title":"Eur. J. Radiol."},{"key":"10.1016\/j.ejrad.2026.113126_b0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2022.110185","article-title":"Assessment of hepatic steatosis based on virtual non-contrast computed tomography: initial experiences with a photon counting scanner approved for clinical use","volume":"149","author":"Niehoff","year":"2022","journal-title":"Eur. J. Radiol."},{"issue":"1","key":"10.1016\/j.ejrad.2026.113126_b0190","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1186\/s12880-024-01419-w","article-title":"The reliability of virtual non-contrast reconstructions of photon-counting detector CT scans in assessing abdominal organs","volume":"24","author":"Dud\u00e1s","year":"2024","journal-title":"BMC Med. Imaging"},{"issue":"12","key":"10.1016\/j.ejrad.2026.113126_b0195","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0316099","article-title":"Generation of deep learning based virtual non-contrast CT using dual-layer dual-energy CT and its application to planning CT for radiotherapy","volume":"19","author":"Kim","year":"2024","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.ejrad.2026.113126_b0200","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1007\/s11548-021-02468-0","article-title":"Spectral augmentation for heart chambers segmentation on conventional contrasted and unenhanced CT scans: an in-depth study","volume":"16","author":"Lartaud","year":"2021","journal-title":"Int. J. Comput. Assist. Radiol. Surg."},{"issue":"6","key":"10.1016\/j.ejrad.2026.113126_b0205","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1007\/s11604-014-0308-y","article-title":"Can virtual non-enhanced CT be used to replace true non-enhanced CT for the detection of palpable cervical lymph nodes? a preliminary study","volume":"32","author":"Yang","year":"2014","journal-title":"Jpn J. Radiol."}],"container-title":["European Journal of Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X26004742?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0720048X26004742?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:46:43Z","timestamp":1790232403000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0720048X26004742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":41,"alternative-id":["S0720048X26004742"],"URL":"https:\/\/doi.org\/10.1016\/j.ejrad.2026.113126","relation":{},"ISSN":["0720-048X"],"issn-type":[{"value":"0720-048X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of parotid lesions with dual-energy CT: Can virtual unenhanced images permit selective omission of true unenhanced acquisition?","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejrad.2026.113126","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"113126"}}