{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T11:44:43Z","timestamp":1773056683260,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,16]],"date-time":"2021-04-16T00:00:00Z","timestamp":1618531200000},"content-version":"vor","delay-in-days":105,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ejropen.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Radiology Open"],"published-print":{"date-parts":[[2021]]},"DOI":"10.1016\/j.ejro.2021.100347","type":"journal-article","created":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T15:01:33Z","timestamp":1619190093000},"page":"100347","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Diagnostic accuracy of the attenuation value in abdominal contrast enhanced dynamic multi-detector-row computed tomography for esophageal varices in patients with liver cirrhosis"],"prefix":"10.1016","volume":"8","author":[{"given":"Yasuhiro","family":"Inokuchi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Uematsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuneyuki","family":"Takashina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"36","key":"10.1016\/j.ejro.2021.100347_bib0005","doi-asserted-by":"crossref","first-page":"5853","DOI":"10.3748\/wjg.v12.i36.5853","article-title":"Doppler study of hepatic vein cirrhotic patients: correlation with liver dysfunction and hepatic hemodynamics","volume":"12","author":"Sudhamshu","year":"2006","journal-title":"World J. Gastroenterol."},{"issue":"2","key":"10.1016\/j.ejro.2021.100347_bib0010","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0950-3528(97)90045-2","article-title":"Ascites and renal functional abnormalities in cirrhosis: pathogenesis and treatment","volume":"11","author":"Gines","year":"1997","journal-title":"Baillieres Clin. Gastroenterol."},{"issue":"8","key":"10.1016\/j.ejro.2021.100347_bib0015","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1111\/j.1478-3231.2010.02272.x","article-title":"Refractory ascites: pathogenesis, definition and therapy of a severe complication in patients with cirrhosis","volume":"30","author":"Salerno","year":"2010","journal-title":"Liver Int."},{"issue":"1","key":"10.1016\/j.ejro.2021.100347_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0889-8553(21)00175-8","article-title":"Pathophysiology of portal hypertension","volume":"21","author":"Bosch","year":"1992","journal-title":"Gastroenterol. Clin. North Am."},{"issue":"53","key":"10.1016\/j.ejro.2021.100347_bib0025","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.jhep.2010.06.004","article-title":"Revising consensus in portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension","author":"de Franchis","year":"2010","journal-title":"J. Hepatol."},{"issue":"2","key":"10.1016\/j.ejro.2021.100347_bib0030","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1053\/jhep.2003.50050","article-title":"Endoscopic screening for esophageal varices in cirrhosis: is it ever cost effective?","volume":"37","author":"Spiegel","year":"2003","journal-title":"Hepatology"},{"issue":"10","key":"10.1016\/j.ejro.2021.100347_bib0035","doi-asserted-by":"crossref","first-page":"3039","DOI":"10.1111\/j.1572-0241.2001.04692.x","article-title":"Screening for esophageal varices among patients with cirrhosis of the liver","volume":"96","author":"Talwalkar","year":"2001","journal-title":"Am. J. Gastroenterol."},{"issue":"1","key":"10.1016\/j.ejro.2021.100347_bib0040","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/imj.12590","article-title":"Portal hypertension: pathophysiology, diagnosis and management","volume":"45","author":"Bloom","year":"2015","journal-title":"Intern. Med. J."},{"issue":"2 Suppl. 1","key":"10.1016\/j.ejro.2021.100347_bib0045","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/hep.20993","article-title":"The hyperdynamic circulation of chronic liver diseases: from the patient to the molecule","volume":"43","author":"Iwakiri","year":"2006","journal-title":"Hepatology"},{"issue":"8","key":"10.1016\/j.ejro.2021.100347_bib0050","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1136\/gut.52.8.1188","article-title":"Liver microbubble transit time compared with histology and Child-Pugh score in diffuse liver disease: a cross sectional study","volume":"52","author":"Blomely","year":"2003","journal-title":"Gut"},{"issue":"9164","key":"10.1016\/j.ejro.2021.100347_bib0055","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1016\/S0140-6736(98)06373-9","article-title":"Non-invasive diagnosis of hepatic cirrhosis by transit-time analysis of an ultrasound contrast agent","volume":"353","author":"Albrecht","year":"1999","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.ejro.2021.100347_bib0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0121601","article-title":"Severe portal hypertension in cirrhosis: evaluation of perfusion parameters with contrast enhanced ultrasonography","volume":"10","author":"Jeong","year":"2015","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.ejro.2021.100347_bib0065","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.ejrad.2010.07.026","article-title":"Detection of hepatocellular carcinoma by Gd-EOB-DTPA-enhanced liver MRI: comparison with triple phase 64 detector row helical CT","volume":"80","author":"Akai","year":"2011","journal-title":"Eur. J. Radiol."},{"issue":"3","key":"10.1016\/j.ejro.2021.100347_bib0070","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1080\/00325481.2017.1241664","article-title":"Computed tomography for the diagnosis of varices in liver cirrhosis: a systematic review and meta-analysis of observational studies","volume":"129","author":"Deng","year":"2017","journal-title":"Postgrad. Med."},{"issue":"3","key":"10.1016\/j.ejro.2021.100347_bib0075","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.acra.2014.10.001","article-title":"Quantitative imaging: quantification of liver shape on CT using the statistical shape model to evaluate hepatic fibrosis","volume":"22","author":"Hori","year":"2015","journal-title":"Acad. Radiol."},{"issue":"1","key":"10.1016\/j.ejro.2021.100347_bib0080","first-page":"13","article-title":"Basic knowledge to achieve optimal enhancement of CT","volume":"56","author":"Awai","year":"2011","journal-title":"Nichidoku-Iho"},{"issue":"1","key":"10.1016\/j.ejro.2021.100347_bib0085","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1148\/radiol.10090908","article-title":"Intravenous contrast medium administration and scan timing at CT: considerations and approaches","volume":"256","author":"Bae","year":"2010","journal-title":"Radiology"},{"issue":"5","key":"10.1016\/j.ejro.2021.100347_bib0090","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.2214\/ajr.173.5.10541087","article-title":"Cirrhotic liver enhancement on dual-phase helical CT: comparison with noncirrhotic livers in 146 patients","volume":"173","author":"Vignaux","year":"1999","journal-title":"AJR Am. J. Roentgenol."},{"issue":"9","key":"10.1016\/j.ejro.2021.100347_bib0095","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.1016\/j.ultrasmedbio.2019.05.028","article-title":"A novel non-invasive method for predicting liver fibrosis by quantifying the hepatic vein waveform","volume":"45","author":"Soroida","year":"2019","journal-title":"J. Ultrasound Med. Biol."},{"issue":"2","key":"10.1016\/j.ejro.2021.100347_bib0100","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1006005","article-title":"A multiscale modelling approach to assess the impact of metabolic zonation and microperfusion on the hepatic carbohydrate metabolism","volume":"14","author":"Berndt","year":"2018","journal-title":"PLoS Comput. Biol."},{"issue":"25","key":"10.1016\/j.ejro.2021.100347_bib0105","doi-asserted-by":"crossref","first-page":"8005","DOI":"10.3748\/wjg.v20.i25.8005","article-title":"Peculiar characteristics of portal-hepatic hemodynamics of alcoholic cirrhosis","volume":"220","author":"Bolognesi","year":"2014","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.ejro.2021.100347_bib0110","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1007\/s00261-001-0095-7","article-title":"Hepatofugal portal flow in advanced liver cirrhosis with spontaneous portosystemic shunts: effects on parenchymal hepatic enhancement at dual-phase helical CT","volume":"27","author":"Vignaux","year":"2002","journal-title":"Abdom. Imaging"},{"issue":"1","key":"10.1016\/j.ejro.2021.100347_bib0115","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1148\/radiol.12112452","article-title":"Hepatic fibrosis: evaluation with semiquantitative contrast-enhanced CT","volume":"266","author":"Varenika","year":"2013","journal-title":"Radiology"},{"issue":"1","key":"10.1016\/j.ejro.2021.100347_bib0120","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1148\/radiol.14141435","article-title":"Equilibrium contrast-enhanced CT imaging to evaluate hepatic fibrosis: initial validation by comparison with histopathologic sampling","volume":"275","author":"Bandula","year":"2015","journal-title":"Radiology"},{"issue":"3","key":"10.1016\/j.ejro.2021.100347_bib0125","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1148\/radiology.216.3.r00se26718","article-title":"Abdominal helical CT: evaluation of optimal doses of intravenous contrast material a prospective randomized study","volume":"216","author":"Yamashita","year":"2000","journal-title":"Radiology"},{"issue":"9","key":"10.1016\/j.ejro.2021.100347_bib0130","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1007\/s00330-003-1904-x","article-title":"Effect of contrast injection protocol with dose tailored to patient weight and fixed injection duration on aortic and hepatic enhancement at multidetector-row helical CT","volume":"13","author":"Awai","year":"2003","journal-title":"Eur. Radiol."},{"issue":"2","key":"10.1016\/j.ejro.2021.100347_bib0135","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.ejrad.2005.11.037","article-title":"Multiphasic contrast-enhanced multidetector-row CT of liver: contrast-enhancement theory and practical scan protocol with a combination of fixed injection duration and patients\u2019 body-weight-tailored dose of contrast material","volume":"58","author":"Ichikawa","year":"2006","journal-title":"Eur. J. Radiol."},{"issue":"10","key":"10.1016\/j.ejro.2021.100347_bib0140","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.crad.2015.06.077","article-title":"Portal hypertension: a review of portosystemic collateral pathways and endovascular interventions","volume":"70","author":"Pillai","year":"2015","journal-title":"Clin. Radiol."},{"issue":"3","key":"10.1016\/j.ejro.2021.100347_bib0145","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/s11604-006-0111-5","article-title":"Enhancement of the liver on dynamic MDCT: investigation among three groups consisting of noncirrhotic patients and cirrhotic patients with and without a large portosystemic shunt","volume":"25","author":"Naruo","year":"2007","journal-title":"Radiat. Med."},{"issue":"12:2","key":"10.1016\/j.ejro.2021.100347_bib0150","article-title":"Validation of the FIB4 in a Japanese nonalcoholic fatty liver disease population","volume":"5","author":"Sumida","year":"2012","journal-title":"BMC Gastroenterol."},{"issue":"42","key":"10.1016\/j.ejro.2021.100347_bib0155","doi-asserted-by":"crossref","first-page":"e1795","DOI":"10.1097\/MD.0000000000001795","article-title":"Diagnostic accuracy of APRI, AAR, FIB-4, FI, king, lok, forns, and FibroIndex scores in predicting the presence of esophageal varices in liver cirrhosis: a systematic review and meta-analysis","volume":"94","author":"Han","year":"2015","journal-title":"Medicine (Baltimore)"},{"issue":"26","key":"10.1016\/j.ejro.2021.100347_bib0160","first-page":"4806","article-title":"Predictors of esophageal varices and first variceal bleeding in liver cirrhosis patients","volume":"23","author":"Bledar","year":"2015","journal-title":"World J. Gastroenterol."},{"issue":"5","key":"10.1016\/j.ejro.2021.100347_bib0165","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/RMR.0000000000000177","article-title":"Magnetic resonance elastography of liver: current update","volume":"27","author":"Hoodeshenas","year":"2018","journal-title":"Top. Magn. Reson. Imaging"},{"issue":"4","key":"10.1016\/j.ejro.2021.100347_bib0170","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.jhep.2010.07.033","article-title":"Elastography for the diagnosis of severity of fibrosis in chronic liver disease: a meta-analysis of diagnostic accuracy","volume":"54","author":"Tsochatzis","year":"2011","journal-title":"J. Hepatol."},{"key":"10.1016\/j.ejro.2021.100347_bib0175","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.ejrad.2018.04.012","article-title":"Usefulness of new subtraction algorithm in estimating degree of liver fibrosis by calculating extracellular volume fraction obtained from routine liver CT protocol equilibrium phase data: preliminary experience","volume":"103","author":"Shinagawa","year":"2018","journal-title":"Eur. J. Radiol."}],"container-title":["European Journal of Radiology Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352047721000277?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352047721000277?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:54:02Z","timestamp":1762433642000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2352047721000277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":35,"alternative-id":["S2352047721000277"],"URL":"https:\/\/doi.org\/10.1016\/j.ejro.2021.100347","relation":{},"ISSN":["2352-0477"],"issn-type":[{"value":"2352-0477","type":"print"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic accuracy of the attenuation value in abdominal contrast enhanced dynamic multi-detector-row computed tomography for esophageal varices in patients with liver cirrhosis","name":"articletitle","label":"Article Title"},{"value":"European Journal of Radiology Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejro.2021.100347","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100347"}}