{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T20:54:35Z","timestamp":1760820875065,"version":"3.40.5"},"reference-count":35,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["ejso.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Surgical Oncology (EJSO)"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.ejso.2017.02.010","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T19:31:40Z","timestamp":1488223900000},"page":"1365-1371","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Is less also better? A single-institution experience on treatment of early stage Malignant Pleural Mesothelioma"],"prefix":"10.1016","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6267-0099","authenticated-orcid":false,"given":"P.","family":"Bertoglio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.C.","family":"Ambrogi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Chella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Aprile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Dini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Korasidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Fanucchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mussi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"14","key":"10.1016\/j.ejso.2017.02.010_bib1","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1200\/JCO.2003.11.136","article-title":"Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma","volume":"21","author":"Vogelzang","year":"2003","journal-title":"J\u00a0Clin Oncol"},{"issue":"6","key":"10.1016\/j.ejso.2017.02.010_bib2","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1586\/17476348.2016.1171147","article-title":"The role of thoracic surgery in the management of mesothelioma: an expert opinion on the limited evidence","volume":"10","author":"Bertoglio","year":"2016","journal-title":"Expert Rev Respir Med"},{"issue":"3","key":"10.1016\/j.ejso.2017.02.010_bib3","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.jtcvs.2007.10.054","article-title":"Extrapleural pneumonectomy versus pleurectomy\/decortication in the surgical management of malignant pleural mesothelioma: results in 663 patients","volume":"135","author":"Flores","year":"2008","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"1","key":"10.1016\/j.ejso.2017.02.010_bib4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0169-5002(95)00508-0","article-title":"A\u00a0proposed new international TNM staging system for malignant pleural mesothelioma from the International Mesothelioma Interest Group","volume":"14","author":"Rusch","year":"1996","journal-title":"Lung Cancer"},{"issue":"Suppl. 2","key":"10.1016\/j.ejso.2017.02.010_bib5","first-page":"S238","article-title":"Management of malignant pleural mesothelioma-The European experience","volume":"6","author":"Opitz","year":"2014","journal-title":"J\u00a0Thorac Dis"},{"issue":"11","key":"10.1016\/j.ejso.2017.02.010_bib6","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1097\/JTO.0b013e31826915f1","article-title":"Initial analysis of the international association for the study of lung cancer mesothelioma database","volume":"7","author":"Rusch","year":"2012","journal-title":"J\u00a0Thorac Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2017.02.010_bib7","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S1556-0864(15)31536-7","article-title":"Macroscopic complete resection: the goal of primary surgery in multimodality therapy for pleural mesothelioma","volume":"1","author":"Sugarbaker","year":"2006","journal-title":"J\u00a0Thorac Oncol"},{"issue":"1","key":"10.1016\/j.ejso.2017.02.010_bib8","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/ejcts\/ezv039","article-title":"Pleural recurrence of thymoma: surgical resection followed by hyperthermic intrathoracic perfusion chemotherapy\u2020","volume":"49","author":"Ambrogi","year":"2016","journal-title":"Eur J Cardiothorac Surg"},{"year":"2010","series-title":"Common Terminology Criteria for Adverse Events version 4.03","author":"Institute, U.D.o.H.a.H.S.N.I.o.H.N.C","key":"10.1016\/j.ejso.2017.02.010_bib9"},{"issue":"4","key":"10.1016\/j.ejso.2017.02.010_bib10","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1080\/00015458.2014.11681020","article-title":"Malignant pleural mesothelioma: rationale for a new TNM classification","volume":"114","author":"De Laet","year":"2014","journal-title":"Acta Chir Belg"},{"issue":"8","key":"10.1016\/j.ejso.2017.02.010_bib11","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S1470-2045(11)70149-8","article-title":"Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study","volume":"12","author":"Treasure","year":"2011","journal-title":"Lancet Oncol"},{"issue":"12","key":"10.1016\/j.ejso.2017.02.010_bib12","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S1470-2045(11)70307-2","article-title":"The MARS feasibility trial: conclusions not supported by data","volume":"12","author":"Weder","year":"2011","journal-title":"Lancet Oncol"},{"issue":"28","key":"10.1016\/j.ejso.2017.02.010_bib13","doi-asserted-by":"crossref","first-page":"6881","DOI":"10.1200\/JCO.20005.14.589","volume":"23","author":"van Meerbeeck","year":"2005","journal-title":"J\u00a0Clin Oncol"},{"issue":"6","key":"10.1016\/j.ejso.2017.02.010_bib14","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1093\/ejcts\/ezv436","article-title":"The staging of malignant pleural mesothelioma: are we any nearer to squaring the circle?","volume":"49","author":"Waller","year":"2016","journal-title":"Eur J Cardiothorac Surg"},{"issue":"3","key":"10.1016\/j.ejso.2017.02.010_bib15","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.thorsurg.2016.04.003","article-title":"Current treatment of mesothelioma: extrapleural pneumonectomy versus pleurectomy\/decortication","volume":"26","author":"Wolf","year":"2016","journal-title":"Thorac Surg Clin"},{"issue":"10","key":"10.1016\/j.ejso.2017.02.010_bib16","doi-asserted-by":"crossref","first-page":"1692","DOI":"10.1097\/JTO.0b013e3181ed0489","article-title":"A\u00a0systematic review of extrapleural pneumonectomy for malignant pleural mesothelioma","volume":"5","author":"Cao","year":"2010","journal-title":"J\u00a0Thorac Oncol"},{"issue":"2","key":"10.1016\/j.ejso.2017.02.010_bib17","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1258\/jrsm.2010.100345","article-title":"A\u00a0systematic review of lung-sparing extirpative surgery for pleural mesothelioma","volume":"104","author":"Teh","year":"2011","journal-title":"J\u00a0R Soc Med"},{"issue":"3","key":"10.1016\/j.ejso.2017.02.010_bib18","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.lungcan.2013.04.024","article-title":"Systematic review of pleurectomy in the treatment of malignant pleural mesothelioma","volume":"81","author":"Cao","year":"2013","journal-title":"Lung Cancer"},{"issue":"4","key":"10.1016\/j.ejso.2017.02.010_bib19","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.jtcvs.2012.12.037","article-title":"Hyperthermic intraoperative pleural cisplatin chemotherapy extends interval to recurrence and survival among low-risk patients with malignant pleural mesothelioma undergoing surgical macroscopic complete resection","volume":"145","author":"Sugarbaker","year":"2013","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"24 Suppl.","key":"10.1016\/j.ejso.2017.02.010_bib20","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2217\/fon.15.286","article-title":"Pleurectomy\/decortication and hyperthermic intrapleural chemotherapy for malignant pleural mesothelioma: initial experience","volume":"11","author":"Migliore","year":"2015","journal-title":"Future Oncol"},{"issue":"4","key":"10.1016\/j.ejso.2017.02.010_bib21","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1093\/ejcts\/ezs418","article-title":"Cytoreductive surgery and hyperthermic intrathoracic chemotherapy perfusion for malignant pleural tumours: perioperative management and clinical experience","volume":"43","author":"Ried","year":"2013","journal-title":"Eur J Cardiothorac Surg"},{"issue":"3","key":"10.1016\/j.ejso.2017.02.010_bib22","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/ejcts\/ezu217","article-title":"Assessment of cisplatin concentration and depth of penetration in human lung tissue after hyperthermic exposure","volume":"47","author":"Ried","year":"2015","journal-title":"Eur J Cardiothorac Surg"},{"issue":"4","key":"10.1016\/j.ejso.2017.02.010_bib23","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0022-5223(99)70297-7","article-title":"Pleural space perfusion with cisplatin in the multimodality treatment of malignant mesothelioma: a feasibility and pharmacokinetic study","volume":"117","author":"Ratto","year":"1999","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"2","key":"10.1016\/j.ejso.2017.02.010_bib24","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.jtcvs.2012.10.042","article-title":"Intraoperative hyperthermic chemotherapy perfusion for malignant pleural mesothelioma: an in\u00a0vitro evaluation","volume":"145","author":"Cameron","year":"2013","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"1","key":"10.1016\/j.ejso.2017.02.010_bib25","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.lungcan.2011.12.009","article-title":"Extrapleural pneumonectomy for early stage malignant pleural mesothelioma: a harmful procedure","volume":"77","author":"Rena","year":"2012","journal-title":"Lung Cancer"},{"issue":"3","key":"10.1016\/j.ejso.2017.02.010_bib26","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1002\/jso.21261","article-title":"Symptomatic and quality of life changes after extrapleural pneumonectomy for malignant pleural mesothelioma","volume":"100","author":"Ambrogi","year":"2009","journal-title":"J\u00a0Surg Oncol"},{"issue":"9","key":"10.1016\/j.ejso.2017.02.010_bib27","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1002\/1097-0142(19941101)74:9<2460::AID-CNCR2820740912>3.0.CO;2-N","article-title":"Intrapleural treatment with recombinant gamma-interferon in early stage malignant pleural mesothelioma","volume":"74","author":"Boutin","year":"1994","journal-title":"Cancer"},{"issue":"1","key":"10.1016\/j.ejso.2017.02.010_bib28","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.lungcan.2009.08.019","article-title":"Survival after trimodality therapy for malignant pleural mesothelioma: radical pleurectomy, chemotherapy with Cisplatin\/Pemetrexed and radiotherapy","volume":"71","author":"B\u00f6l\u00fckbas","year":"2011","journal-title":"Lung Cancer"},{"issue":"3","key":"10.1016\/j.ejso.2017.02.010_bib29","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1097\/JTO.0000000000000064","article-title":"Does surgery improve survival of patients with malignant pleural mesothelioma?: a multicenter retrospective analysis of 1365 consecutive patients","volume":"9","author":"Bovolato","year":"2014","journal-title":"J\u00a0Thorac Oncol"},{"issue":"4","key":"10.1016\/j.ejso.2017.02.010_bib30","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1016\/j.athoracsur.2014.11.050","article-title":"Persistent lung expansion after pleural talc poudrage in non-surgically resected malignant pleural mesothelioma","volume":"99","author":"Rena","year":"2015","journal-title":"Ann Thorac Surg"},{"issue":"6","key":"10.1016\/j.ejso.2017.02.010_bib31","first-page":"E254","article-title":"Guidelines for the diagnosis and treatment of malignant pleural mesothelioma","volume":"5","author":"van Zandwijk","year":"2013","journal-title":"J\u00a0Thorac Dis"},{"issue":"11","key":"10.1016\/j.ejso.2017.02.010_bib32","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1097\/JTO.0000000000000661","article-title":"A\u00a0new prognostic score supporting treatment allocation for multimodality therapy for malignant pleural mesothelioma: a review of 12 years' experience","volume":"10","author":"Opitz","year":"2015","journal-title":"J\u00a0Thorac Oncol"},{"issue":"4","key":"10.1016\/j.ejso.2017.02.010_bib33","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.ijrobp.2005.03.041","article-title":"Hemithoracic radiation therapy after pleurectomy\/decortication for malignant pleural mesothelioma","volume":"63","author":"Gupta","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"1","key":"10.1016\/j.ejso.2017.02.010_bib34","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.lungcan.2013.10.013","article-title":"Radical pleurectomy\/decortication followed by high dose of radiation therapy for malignant pleural mesothelioma. Final results with long-term follow-up","volume":"83","author":"Minatel","year":"2014","journal-title":"Lung Cancer"},{"issue":"1","key":"10.1016\/j.ejso.2017.02.010_bib35","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.ijrobp.2014.08.343","article-title":"Hemithoracic intensity modulated radiation therapy after pleurectomy\/decortication for malignant pleural mesothelioma: toxicity, patterns of failure, and a matched survival analysis","volume":"91","author":"Chance","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["European Journal of Surgical Oncology (EJSO)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798317303566?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0748798317303566?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T00:43:46Z","timestamp":1568853826000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0748798317303566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["S0748798317303566"],"URL":"https:\/\/doi.org\/10.1016\/j.ejso.2017.02.010","relation":{},"ISSN":["0748-7983"],"issn-type":[{"type":"print","value":"0748-7983"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is less also better? A single-institution experience on treatment of early stage Malignant Pleural Mesothelioma","name":"articletitle","label":"Article Title"},{"value":"European Journal of Surgical Oncology (EJSO)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ejso.2017.02.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.","name":"copyright","label":"Copyright"}]}}